KEGG   Escherichia coli O9 HS (commensal): EcHS_A2811
Entry
EcHS_A2811        CDS       T00591                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase, alpha subunit
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
ecx  Escherichia coli O9 HS (commensal)
Pathway
ecx00230  Purine metabolism
ecx00240  Pyrimidine metabolism
ecx01100  Metabolic pathways
ecx01232  Nucleotide metabolism
Module
ecx_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
ecx_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ecx00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    EcHS_A2811 (nrdE)
   00240 Pyrimidine metabolism
    EcHS_A2811 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ecx03400]
    EcHS_A2811 (nrdE)
Enzymes [BR:ecx01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     EcHS_A2811 (nrdE)
DNA repair and recombination proteins [BR:ecx03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    EcHS_A2811 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC RNR_N Ribonuc_red_lgN
Other DBs
NCBI-ProteinID: ABV07061
LinkDB
Position
2818791..2820935
AA seq 714 aa
MATTTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFIATHVRPNSVTFSSQQ
QRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHTSGFRFQTFLGAWKFYTSYTLKTFDGK
RYLEDFADRVTMVALTLAQGDETLALQLTDEMLSGRFQPATPTFLNCGKQQRGELVSCFL
LRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLED
AFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLA
KENAQMALFSPYDVERVYGKPFADVAISQHYDELVADERIRKKYLNARDFFQRLAEIQFE
SGYPYIMYEDTVNRANPIAGRINMSNLCSEILQVNSASEYDENLDYTRTGHDISCNLGSL
NIAHTMDSPDFARTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAR
EGIAYGSPEALDFTNLYFYAITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQG
NWQPKTAKVGELFTRSGITLPTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATS
SIHPIVAKVEIRKEGKTGRVYYPAPFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQG
LSLTLFFPDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL
NT seq 2145 nt   +upstreamnt  +downstreamnt
ttggcaacgacaaccgcagaatgcctgacgcaggaaacgatggattaccacgcgctgaat
gcgatgcttaacctctacgatagcgcaggtcgcattcagttcgataaagaccgccaggcc
gttgacgcctttattgcgacgcatgtgcgtccgaacagtgtgaccttcagtagccagcag
cagcgcctgaactggctggtcaacgaaggttactatgatgaaagcgttcttaatcgctac
tctcgcgactttgtcattacgctgtttgcccacgcacacaccagcggttttcgtttccag
acattcctcggggcatggaagttttacaccagctatacgttgaagacattcgacggtaaa
cgttatctggaagattttgccgatcgagtcacgatggtggcgctgacgctggcacaaggc
gatgagacgctggcgttgcaactgacagatgaaatgctgtcaggacgctttcagccagcc
acgccaacattcctcaactgcggtaagcagcagcgcggcgaactggtttcctgttttttg
ctgcgtattgaagacaatatggagtcgattggtcgggcggtaaattccgcactgcaactg
tcgaaacgcggcggcggcgtagcatttttgctgtcgaatctgcgagaagcgggcgcgcca
attaaacgtattgaaaatcaatcttctggcgtaattccggtgatgaaaatgctggaagac
gcattttcctatgccaaccaactcggcgctcgtcagggggctggtgcagtctatttacat
gctcatcatcccgatattctgcgttttctcgacacgaaacgggaaaatgccgacgaaaaa
atccgcattaaaacactgtcgcttggcgtggtgatcccggatatcactttccatctggca
aaagagaatgcgcagatggcgctgttttcgccttatgacgtagagcgagtttatggcaag
ccgtttgccgatgtggccatcagccaacactatgacgaactggttgccgatgaacgcatt
cgcaaaaaatacctcaacgcccgtgatttcttccagcgactggcagaaatccagtttgag
tccggctatccctacatcatgtatgaagacacggtaaaccgtgctaaccctatcgccggg
cgcataaatatgagtaatctctgctcagaaattttgcaggttaacagcgcctcagagtat
gacgagaatctcgactatacccgcacaggccatgatatttcctgcaatttaggttcgttg
aatattgcgcacaccatggattcccccgattttgcccgcacggtagagactgccgtgcgc
ggtttaacggcagtatcagatatgagtcatatccgcagcgtgccgtccatcgaagccgga
aatgccgcctcgcacgccatcggactggggcagatgaatttacacggctatctggcgcga
gaaggcatcgcttatggttcgccggaagcactggatttcaccaatctctatttctatgcc
atcacctggcatgcactgcgtacctcgatgttgctggcacgcgaacgcggtgaaaccttc
gccgggttcaaacagtcacgctatgccagtggtgaatattttagccaatatctgcaaggg
aactggcagccgaaaacggcgaaagttggcgaactgtttacccgtagcggtattacgtta
cctacccgtgagatgtgggcgcagctgcgcgacgacgtgatgcgctacggcatatacaac
cagaatcttcaggcggtgccgccaaccggttctatctcttatatcaaccatgctacgtcg
agtattcatccgattgtggcgaaagtagagatacgcaaagagggcaaaacaggacgcgtt
tactaccctgccccgtttatgactaacgagaatctggcgctgtatcaggacgcttacgaa
attggcgcagaaaagatcatcgacacctacgcggaagcgactcgccatgtcgatcagggg
ctgtcgctgacgctttttttccccgataccgccaccactcgcgatatcaacaaagcgcag
atttacgcctggcgcaagggtatcaaaacgctctattacatccgcctgcgtcagatggcg
ctggaaggcactgaaattgaaggctgcgtctcctgtgcactttaa

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