Electrophorus electricus (electric eel): 113570521 Help Entry 113570521         CDS       T05787                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism eee  Electrophorus electricus (electric eel) Pathway eee04020   Calcium signaling pathway eee04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:eee00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     113570521 (ryr3)    04020 Calcium signaling pathway     113570521 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:eee04040]     113570521 (ryr3) Ion channels [BR:eee04040]  Voltage-gated cation channels   Ryanodine receptor    113570521 (ryr3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 Ins145_P3_rec SPRY MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 DUF2207_C EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  113570521 NCBI-ProteinID:  XP_026854758 LinkDB All DBs Position Unknown AA seq 4960 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVATIQKENRKFCLSAEGLGNRLCYLEPTSEAKYVPP DLCICTFVLEQSLSVRALQEMLATVVQNGEGLPDHERWRFLRRAGQGGGHRTLLYGHAIL LRHSFSGMYLACLKTSRSLTDKLSFDVGLQEESTGEACWWTIHPASKQRSEGEKVRIGDD LILVSVSSERYLHLSISNGNIQVDASFMQTLWNVQPTCSGSNVAVGYLLGGQVMRLFRGH DESLTIPGSDKSEEQQRIVNYEAGKGGSRARSLWRVEPLRISWSGSHIRWGQPFRLRHLS TGHYLGQTDDRGLVLLDREKSDTTATAFCFRPSKEKVDSGPKRDIDGMGVAEIKYGDSVC FIMHAATGLWLSYQAPDAKSSRLGPLKRRAFLYPEGHMDDGVILQLCQHEESRAARIIRN TTHLFTQFIRGLDELKGEKASEVNLPVVEVLQNLNDLITYFQQPDSELDHEEKQRQLRSL IKRQDLFKEEGMLTLLSICIDRLNVYNSAAEFEEVAGEEAGEAWKDILNLLYELLAALIR GNRPNCTQFSRRLDWLVSKLERLESSSGILEALHCILTESPEALNIIQKDHIKSIISLLY KHGRNHKILDILCSLCVCNGVAVRANQNFICDHLLPRRDLLLQTRLVNDVQSMRPNIYLG MSEGSAQYKKWYFELMIDQVDHFMTGEATHLRVGWATTKGYAPYPGGGEGWGGNGVGDDL YSYGFDGLHLWSGRIPRAVASINQHLLNPDDVVSCCLDLGAPSMSFRINGQPVQGMFEDF NTDGFFFPVVSFSAGVKVRFLLGGRHGDFKFLPPAGYAPCYEALLPKEKMRVEPVKEYKR DAEGVRDLLGTTQFLSQASFIPIPVNTSQIVLPPHLDNVRDKLAENIHELWGMNKIELGW IYGKVRDDNKRQHPCLVDFSKLPETEKNYNLQMSTETIKTLLSLGCHVVQVNVNAEDDLK KLKLPKDYVMSNGYKPSPLDLSDVKLTSGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQ DLKSRRNPRLVPYALLDERTKKSNRDSLREAIRTLVGYGYNIDPPDQEAAHVVEKQSVEN IRFFRVEKTYAVQSGKWYFEFEAVTGGEMCVGWARPGCRPNVELGMDDQAYVFDGYRGRR VHMGSHFFGRTWNKGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFTDFETEDGFIPV CSLGLSQIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPED HEHIEVTRIDGTVDTPPCLKVTHKTFGTQASNSDMIYCRLSMPVEFYPGPRKITNINEVI ADDQKSKKDDSGKIDYGSITKYFHSVRVFAGQDPASVWVGWVTPDYHYYSKNFNLSKVRT VTVTLGDERGRVHESVRRSNCYMVCVGDITSGSSGRNNIDLEIGCHIDLVSGLVSFTANG KELPTVYQVESNTKLFPAVFVLPTSPNLFQFEFPKIQDAMPLSSAIFKSLQRNPEPQCPP RLDVQTIAAVLWSRMPNSFLSVEAARVSERHGWVVQCLEPLQMMAVHIPEENRCIDIMEL SENEGLRQFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGQLREGFYN VLISIHLETAKEARLMMKDEFIIPITDETCGIRLFCDDNKRHSLPGVGLSTSLVPHLNFA PQCFIRTKREFRYSPEIPLGILKEKAISMLTEAVQGGGTHIRDPVGGSVEYQFVPILKLI DTLLIMGALSSEEVRLILLLIEPNVFGDGKEEEVQPAAVQEVVEKEKEEASCNEEKAVEA GEEETKEPKQPPKGLLQKSLPESVKRQMCELLHYFCDCELKQRIEAIVAFSDGFVAKLQY NQKFRYNELMQALNMSAAVTAKKTKEFRSPPQEQINMLLNFSAGDDCPCPEEIQEELHTF HHDLRLHCGIPMEEEEEEQDTSIKGRLLTLLYKIKGRPQKTEEQPSEQEQAAPTNLKELI SQTMVSWAQECSIQDPELVRSMFSLLRRQYDGIGELLRAMRKSYTISARSVQDAIHLLAS LGQIRSLLSVRMGEEEGQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMQVMVNVLGGD KSKEVAFPKMVASCCRFLCYFCRISRENQKAMFEHLSYLLENSSVGLACPAMRGSTPLDV AASSVMDNNSLALALEEPDLEKVVTYLAGCGLQSCPMLIVKGYPDIGWNPIEGERYLSFL RFAVFVNGESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMQEAIKISEDPTLDLP SLPEGGVSAAGEEGEEEEMAHMGNSIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAI LRSLVPTKDLVGIISIPLKLPVVNKDGSVTEPDMNASFCPEHKAPMVLFLDRVYGIEDQS FLLNLLEVGFLPDLRASASLDTEVLSTTETALAMNRYIGSAVLPLLTRCASLFTHTEHYA MLVDSTLHTIYRLSKGRSLTKAQRDSIEECLLAICRHLRPSMLQQLLRRLVFDVPQLTEY CKMPIKLLTNHYEQNWKYYCLPSGLGSYGMASEEELHLTKKLFWGLFDALSQKKYDAELF KMAMPCLSAIAGALPPDYVDMSPGSTLVKQVSVDAEGNFDPKPISTANISLPEKLDYISN KYAEHCHEKWSQEKLALGWTAGEKVDDQAKTHPLLKPYKALSEKERETYRYPIKESLKSM LALGWNIERTKEGEAMFHQRETEKQHKISESSQGDGFTPTPVDLDNVILSRELQGMVEIV AENYHNIWAKKKKLELNSKGGGTHPLLVPYDTLTAKEKFRDREKAQELFKFLQLNGYAIR RGLKDMEQDSSSMEKRIAYKFLKRLLGYVDSAQEFIAHLEAMATSGKTDKSPHEQEIKFF AKVLLPLIDQYFKNHCLYFLSSPSINLSSSGYASNKEKEMITSLFCKLASLVRHRISLFG SDSATMVSCLHILAHSLDFRTVMKSGSELVKAGVRTFFENAAEDLEKTVENLKLGKLGQS RTQMKGVAQIINYTSVALLPILTALFQHITQHQFGVDLLLDDVQLSCYRILTSLYSLGTG KNIYVEKQLPALGECLATLVGAMPVAFLEPHLNMHNPCSVFNTKTSRERAILSMPDTVEE MCPEMPRLDGLMKDIHDVSESGARYTEMPHVIEVILPMLCNYLSYWWAKGPENTVDGVSC CTTVTSEHLSLILGNIVKILNNNLGIDEASWMKRIAVYTQPIISKAGVDLLRSHFLPTLE KLKKKTVKVAAEEELLRADSRADTQEAELQILDEFAVLCRDLYAFYPMLIRYVDNHRSKW LKNPDADSTELFKMVSEIFILWCKSHNFKREEQNFVVQNEISNLAFLTGDCKTKMSKSGG QDQERRGKKKRRELYSVQTSLIVAAHKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDEE VKDHLRQNLHLQEKTEDPAVQWQLNLYRDVVVKSGAPDPERSLERLQRISAAVFHLEQVE QPLRNKKLVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLMGYQKLWIVAEEYSFE EKLVQDLAVSIGLALALPCVPCVPAGVLSAAVCPAASTLPTEKRERIPARLVSASWPVFG SSGCVAYYRQRCSRQALHEFRLSLRPHHLSRAVCLSSAVKTPMVVEKDEEETEAEVQPDP LNQLILHFSHNALTERSFLEEDPLYIAYADMMAKSCAEDEEEEEEGKEKTFEEKEMEKQK TLYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKLGISILNGGNVAVQQKMLDYLKE KRDAGFFKSLSGLMQSCSVLDLNAFERQKKAESLGMVTEEGSVNVSERGSKVLQNDEFTK DLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDV MDEHGQLNFSKALEVAKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMK LSQDSSQIELLKELLDLQKDMVVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFF DMFLKLKDLTTSDNFKEYDPEGKGIISKKEFQKSMESQKQYTQSEIEFLLSCAEADENDM FNYVEFVERFHEPAKDIGFNMAVLLTNLSEHMPHDSRLATFLDLAESVLSYFEPYLGRIE IMGGAKRIERVYFEISESSREQWEKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTI FEMQLASQISEPDTAERPEEEDEEELQSLLEELAEGEDGSHESASAFTVACTSVKKKMSN CRQMLTFKNMRKQFKKLKKLTIKEIIIGFFSLFWMLFTGFFKSIFSLIFGFFHIIWSSMF GGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVMEPEKAESGDLVVSMEMVQMTAAGEKLE PDAIIDLISPPTKREGKHGSEPGLGDVSEFKTEASPPIEKKKSQKVATEESEPEKADTEN REKEDMAKEEKPEEPVAEEKPAPRKQHGAPKEQPPALMASVFAGLEVYKTKMLNYLARNF YNLRLLALFVAFAINFILLFYKVTGEADDEEEEGLWGGDDDDDDDDDEGGMEFYVLQENT GYMAPTLTFLAILHTIISLLCVVGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPSEDD IKGQWDRLVIATPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFDPTEEA VVKEASLVSWLSSIDTKYYIWKMGVVLTDNSFLYLIWYTTMSILGHYNNFFFAAHLLDIA MGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCD DMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEIYRILFDITFFFFVIVILLAIIQGLII DAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLIN KDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14883 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggcggagaaggggaagatgaaattcagttcttacgaactgatgacgaggtg gtgctccagtgtgttgctaccattcagaaggagaaccgcaaattctgcctctctgctgag ggcctcggaaatcgactgtgctacctagaaccaacctcagaagccaagtatgttcctcct gatttgtgcatctgtacgtttgtgctggagcagtcactctctgtgcgggccctgcaggaa atgctggctaccgtagtacagaatggtgaagggcttcctgatcatgaacgatggaggttt ttaaggcgggcagggcagggcggtggacatcggacactgctgtacggtcacgccatccta ctgagacattcctttagtggaatgtacttggcctgtttaaagacgtcacggtctctgact gataagctgtcatttgacgttggcttacaagaggaatccacaggggaagcttgttggtgg accatccacccggcctcgaagcagaggtctgagggtgagaaggttcgtattggtgatgat ctcatcttggtcagtgtgtcttcagagaggtatttgcacctgtctatctccaatggaaat atccaagtggatgcttctttcatgcaaacactgtggaatgtgcagcctacctgctctggc agcaatgtggcagtgggatatttattgggaggacaagtgatgcgcttgttccgtgggcat gatgagagcctcaccataccaggatctgacaaatctgaagagcagcagaggatagtgaac tatgaggctgggaagggtgggtcccgggccaggtctctgtggagggtggagccacttcgc ataagctggagtggaagccacattcggtggggtcagcccttccgcttgcgccacctgtcc actggtcattacctgggccagacggatgaccgcggcctggtgctgctcgacagagagaag tccgacaccactgctaccgccttctgcttcaggccaagcaaggagaaagtggactctggg ccaaagcgggacatcgacggcatgggggtggcggagatcaagtacggcgactcggtctgc ttcatcatgcatgctgccacgggcctgtggctgtcctaccaggcacccgacgcaaaatct tcccgcttggggccactgaagagaagggccttcctttacccagagggccacatggacgac ggcgtcatcctacagctctgccagcatgaggaatccagagcggcccgcatcatccgcaac accacacaccttttcacccagttcatcagaggcctggatgaactgaagggtgagaaggcc tctgaggtgaatctgcccgtggttgaggtcctgcagaacctcaacgacctcattacctac tttcagcagcccgactcagaactggatcatgaggagaagcagaggcagctccgctcgctc atcaaacggcaggacctcttcaaagaggagggaatgctcacactgctctcgatctgcatt gaccgcctcaacgtgtacaacagtgctgcagagtttgaggaggtggcaggcgaggaggca ggggaggcctggaaggacattctcaacctcctttatgagctgctggctgccctgatccga ggaaataggcccaactgcactcagttctcccgcagactggactggttggtcagcaaattg gagcgtctggagtcatcctcaggcatcctcgaggcactgcactgcatcctaaccgagagt cccgaggctctgaatatcatccagaaggaccacatcaagtccatcatctccctgctctac aagcatggccgtaaccacaagattctggatatcctctgttctctctgcgtctgcaatgga gtggcagtcagagccaatcagaacttcatctgtgatcacctgcttcctaggagggatctg cttctccaaacaagattagtcaatgatgtgcagagcatgagaccaaacatctacctgggc atgagtgagggttcggctcagtataagaagtggtactttgagctgatgattgaccaagtg gaccacttcatgactggagaggccacgcacctccgtgtaggctgggccaccaccaaaggc tatgccccctaccctggaggtggtgagggctggggaggcaatggagtgggcgatgatctc tactcctatggcttcgatgggctgcatctctggtcagggcgaatcccacgagctgtggcc tctattaaccagcatctgctgaacccggatgatgtggtgagctgctgcctggacctcggt gcccccagcatgtcctttcgcatcaatgggcagcctgtccagggcatgttcgaggacttc aacacggacggcttcttcttccccgtggtcagcttctcggcaggggtcaaggttcgcttt ctgttggggggtcgccacggagactttaagttcctgccgccagcaggctatgcaccctgt tatgaggccctgctcccaaaagagaagatgcgtgtggagcctgtgaaggagtataagaga gatgctgagggtgtgagggacctgctggggaccacccagtttctttctcaggcatccttc atccccatacctgtcaataccagccagattgtcctgcctccacatcttgacaatgtgcgt gacaagctggctgagaacatccatgaactctggggtatgaacaaaattgagcttggctgg atctatggcaaggtacgagatgacaacaaaagacagcacccttgcctggttgacttctcc aagctgcctgaaactgaaaagaattataacctgcagatgtcaacagagaccataaagacc ttactatctttgggatgccatgttgtacaagtcaatgttaatgctgaggatgatctgaag aaactgaaacttcccaaggactatgtgatgtcaaatggttataaaccttcgccactagac ctttctgatgtgaaactgacatctggtcaggaggttctggttgataaactggctgaaaat gctcacaacgtttgggccaaagatcgcatcaagcaaggatggacctatggtattcagcag gatttgaaaagcaggcgcaatcctcggctggtgccatatgctttgttagatgaacgcaca aagaagtccaaccgagacagtcttcgggaggccatccgaacactggtcggctatggatac aatatagaccctcctgaccaagaggctgcccatgtggtggagaagcagagtgttgaaaac attcgcttcttccgtgtggagaagacctacgcagtgcagtcagggaagtggtattttgag tttgaggctgtgacgggaggggaaatgtgtgtgggctgggcccggcctggctgcagacct aacgtggagctaggcatggatgatcaggcttacgtatttgatggttacagaggccgccgc gtacacatgggcagtcacttttttgggcggacttggaacaaaggcgatgtggtggggtgc atgattaacatggaggacaaatccatgatcttcactctcaatggggagatcctcatcacc aataaaggctcagagctctgcttcacggactttgagactgaagatggattcatccctgtc tgcagcctgggactttcccagattggccgcatgaacttgggcaaagacgccagcaccttt aagtactacaccatgtgtggcctgcaggagggctttgagccttttgctgtcaacatgaac agagaggtcaccatgtggttcagcaaacgccttcccacgtttgtcaatgtgccagaggac cacgagcacattgaggtgacaaggatcgatggcacagtggacaccccaccgtgtctgaag gtcacccataagacctttgggacgcaggcgagcaacagcgacatgatctactgccgcctg agcatgcctgtagagttttatccaggtcccaggaaaatcacaaacatcaatgaggtgatc gctgatgaccaaaaatccaagaaagatgacagtggaaagatagattatgggagcattaca aagtatttccattcagtgagagtgtttgcaggccaggaccctgcctcagtgtgggtgggc tgggtcaccccagactaccactactacagcaagaacttcaatctcagcaaagtccgcaca gtgaccgtcactctgggggatgagcggggtcgcgtgcatgagagtgtgaggaggagtaat tgctacatggtgtgtgttggagacataaccagtggctcttctggacgcaataatattgat ctggaaatcggttgccacattgacctggtgtctggcctagtctcattcactgccaatggc aaggagctgcccactgtatatcaggttgagtccaacacaaaactgttccctgccgtattt gttctgcccacaagccccaacctgtttcagtttgaatttccaaagatccaggacgccatg cccctgtcttcagccatcttcaagagtttgcaaagaaacccagaaccccagtgcccacca cgtctggatgtgcagaccattgcagctgttctgtggagcaggatgcccaactccttcctg tcagtggaggctgcccgtgtcagtgagaggcatggctgggtggtgcagtgtttggagccg ctgcagatgatggcagtacacattcctgaagaaaacaggtgcatagacatcatggagcta tcagagaacgaaggcctgcggcaattccactaccataccctcaagctctactgtgccttg tgtgctctgggaaacactcgtgtggcccatgccctctgcagccaccttgaccaatcacag ctcctctacaccattgacaaccagtacctgtctgggcagctgcgggagggcttctataac gtgcttatcagcatccacctggagacagccaaggaggcacgcctcatgatgaaggatgag ttcatcatccccatcacagacgagacttgtggcatccggctcttctgtgatgacaacaag cgtcactcactcccgggtgtgggtctgagcacgtcactcgtgccccatctcaacttcgct ccacagtgcttcatcagaaccaaacgggagttccgctacagccctgagatcccactgggc atcctcaaggagaaggccatcagcatgctcacggaggcagtgcagggcggcggcacccac atccgtgaccccgtagggggcagcgtggagtaccagtttgttcccatcctcaaactgatc gacacgctgctgatcatgggagcgttgagcagtgaagaggtccgtctcatcctgctcctc atcgagcccaacgtgtttggggatggcaaggaggaagaggtgcagccggcagcggtgcag gaggtggtggagaaggagaaagaggaggcaagctgtaatgaggagaaggctgtagaggca ggggaggaagagaccaaggagccaaagcagccacccaagggacttctgcagaagagcctg ccggagtctgtcaaacgtcagatgtgtgaactactgcactatttctgcgactgtgagctg aaacagcgcatcgaggccattgttgccttctctgatggctttgtggccaaactgcagtac aaccagaaattccgctacaatgaactcatgcaagccctcaacatgtctgccgctgtcaca gcaaagaagactaaggaattccgttctcctccccaagagcagattaacatgctgctgaac ttcagtgctggggatgactgcccctgccctgaggagatccaagaagagcttcacaccttc caccatgacctgagactgcactgtggaattcccatggaggaggaagaggaggagcaggat acatctatcaagggtcgtctgctcaccctcttatacaaaatcaaagggcgtccacagaaa actgaggaacaaccatcagagcaagagcaggcagctccaaccaacctgaaggagctgatc tcccagacgatggtgagctgggcgcaggagtgtagcatccaggatccggagctggtgcgc agcatgttcagcctgctgcgccggcagtatgatggcatcggcgagctcctgcgcgccatg cgcaagagctacaccatcagtgccaggtccgtgcaggatgccatccacctgctggcctca ctgggccagattcgctcattgctcagcgtgcgcatgggtgaggaggagggacagctcatg atcgatggactgggggacatcatgaacaacaaagtgttctatcagcatccaaatctgatg cgtgttctgggcatgcatgagaccgtcatgcaggtcatggtgaacgtactcgggggtgac aagtctaaggaggttgcattccctaaaatggtcgccagttgctgccgtttcctgtgttac ttctgccgtatcagccgtgagaatcagaaagccatgtttgagcacctgagctatctatta gagaacagcagcgtgggactggcttgtccggccatgaggggctcgactccactggacgtg gctgcttcgtcagtgatggacaacaatagtctggccctggctttagaggagccagacctg gaaaaggtagtgacatacttggctggttgtggactgcagagctgcccgatgctgatagtc aaaggataccctgacatcggatggaaccccatcgaaggagagcgctatctgtccttcctc cgatttgctgtctttgtcaatggtgagagtgtggaggagaacgccaatgtggtggtaaaa ctgctcatcaggcgtcccgagtgcttcggcccagctctgagaggagaggggggccagggc ctactggctgccatgcaggaggctattaaaatctctgaggatcccaccctggacctgccc agccttcctgagggaggagtatctgcggctggagaggaaggtgaggaggaggagatggca cacatgggcaactccattatgtccttctactcagctctcattgacctgctgggacgatgc gccccagagatgcatttaatcaacgcagggaagggtgaagctctgcgtatccgtgccatt ctacgctctctggtgcctaccaaagacctggtgggcatcatcagcatacctctcaaactg ccagtggtcaacaaagatggcagcgtgacggagccagacatgaatgctagcttctgtccc gagcacaaggcgcctatggtgctcttcctggaccgcgtctatggtatcgaggaccaaagc ttcctgttgaacctgctggaggtgggcttcctgcctgacctgcgtgcctccgcctcgttg gacacggaggtgctaagcaccacagagacagccctggccatgaaccggtacattggctca gctgtgctcccactgctgacccgctgcgcctctctcttcacccatactgagcactatgcc atgctcgtggactccaccctccacactatctacaggctgtccaagggccgttcgcttacc aaggcccagagggactccatcgaggagtgcttgcttgccatctgcaggcacctgcggccc tccatgctccagcaactcctgcgtcgcctggtctttgacgtgccacagctcacagagtac tgcaaaatgcccatcaagcttttgaccaatcactatgagcagaattggaaatattactgc ctgccttcaggcctgggcagctatggcatggcctctgaggaggagctccacctcacaaaa aaacttttctggggccttttcgacgcactctctcagaagaaatatgatgcagagctgttc aagatggccatgccttgcctgagtgccatagctggagccctcccacctgactatgtagac atgagtccaggctctactctggttaagcaggtctctgtggacgctgagggcaactttgac cccaagcccatcagcacagccaacatttccctgcctgaaaaactggattacatttctaac aagtatgctgagcactgccacgagaaatggtcacaagaaaagcttgcactaggctggaca gcaggggagaaggtggatgaccaagccaaaacccaccctctactgaaaccgtacaaagca ctcagtgaaaaggaaagggagacctaccgatacccgatcaaggagtccctgaagagcatg ctggcattaggctggaacattgagaggaccaaagagggagaggccatgttccatcagcgg gagacagagaaacagcacaagatctcagagtcttcgcagggagatggatttactccaact cctgtggatttagataacgtaatcctctcgagagagttacagggcatggtagagattgta gcagagaattaccacaatatttgggcaaagaagaagaaactggaactaaatagcaaagga ggtggaactcacccactgctggtgccatatgacactctgacagctaaagaaaagttcaga gaccgggagaaggctcaggagctctttaaatttctgcaactcaatggatatgcaataaga agaggactgaaggatatggaacaggattcctcgtctatggaaaagaggattgcctacaag ttccttaagcggctgctaggttatgtagattctgcccaggaattcatagcccatcttgag gcgatggcaaccagtgggaaaacagacaaatctcctcatgaacaagagattaagttcttt gcaaaggtcctgctgcctttgattgatcagtactttaagaaccactgcctgtacttcctg tcctctcccagtattaacctgagcagcagtgggtatgcctccaacaaagagaaggagatg attaccagtctcttctgtaagttggcctctcttgtcagacacagaatttctctctttggg agtgactctgccacaatggtgagctgtctacacatcttggcacattcactggacttcagg acagtgatgaagtctggctcagagctcgtgaaggctggagtcaggacattctttgagaat gcagcagaagacctggagaagaccgtggagaacctgaagttgggcaaattgggccagtcg cgcacacagatgaaaggagtagctcagatcatcaactacacctcagtggccctgcttccc attcttacagctctcttccagcacatcacccagcaccagtttggggtggacctgctgctg gatgatgttcaactgtcatgctatcgcattctgaccagcctctactctctgggaaccggc aagaacatctatgttgaaaaacagcttcctgcactgggtgagtgcttggccaccctggtg ggagccatgccagtagccttcctggaacctcatctgaacatgcacaacccttgctctgtc ttcaacactaagacatctcgagagagagcaattctgagcatgcccgacacggtggaggag atgtgtcctgaaatgccccgcctggatggcctgatgaaggacattcatgatgtctctgag tctggggcacgctacactgaaatgccacacgtcattgaggtcatcctgcctatgctgtgt aattatctttcttactggtgggctaaaggccctgagaacacagtggatggtgtaagctgc tgtaccacggtcacgtctgagcacctcagcctcatccttggcaacattgttaaaattctc aacaacaacctgggcatcgatgaagcttcctggatgaagcggattgcagtgtacacccag ccaataattagcaaggcgggcgtggaccttctacgaagccacttccttcccacactggag aagctgaagaagaagacagtaaaggtggctgctgaagaggagctgctgagggcagatagc agggctgatacccaggaggccgagctgcagattctggatgagtttgctgtcctctgcagg gacttatatgccttttatccaatgctaatccgctatgtggacaaccacaggtcaaaatgg ctgaagaaccctgatgctgattcaacagagctcttcaaaatggtgtcagagattttcatc ctctggtgtaaatctcataatttcaaaagggaagagcaaaactttgtggtgcaaaatgaa atcagcaatctagccttcctcactggggattgcaagaccaaaatgtcaaagtcaggaggc caggaccaggagaggagagggaagaagaagagaagagaactgtactctgttcagacgtcc ctgattgtagcagcccacaagaagatgctgcccatcggcctgaacatgtgcacccctgga gaccaggagcttatctctctggccaagatccgctacagtctgaaagataccgatgaggag gtaaaggatcacctgaggcagaacctccatcttcaggagaagacggaagacccagcggtt cagtggcagctgaatctctacagggatgtggtggtaaagagtggcgctccagatccagaa cgctcacttgagaggctccagcgcatctcagccgccgtcttccacctggagcaggtggag cagccactgagaaataagaagttggtatggcagaagctgttgtccaaacagcgcaagcgt gctgtggttgcctgctttcgtatggcgccattatataacctccctaggcatcgctctatt aacctcttcctcatgggctatcagaaactctggatagtagcagaggagtactcctttgag gagaagctagtgcaggacctggcagtaagtatcgggctggccctggcgctgccctgtgtg ccgtgtgtgcccgctggcgtcctgtctgccgctgtttgccccgcggccagcaccttgccc accgaaaagcgggaacgcatccctgcccgcctcgtgtccgcatcctggcccgtgtttggc tcctctggttgcgtggcgtactacagacagaggtgcagcagacaggccctgcatgagttt cgcctgagcctccggccccaccacctctctagagcagtctgtctcagctcagccgtgaaa acccccatggttgtggaaaaggacgaggaagagacagaggccgaggttcagcctgaccct ctaaaccagctcatcctccattttagccataatgccctcacggagagaagtttcctggag gaagatcccttgtatattgcatatgcagatatgatggcaaagagctgtgccgaagatgaa gaggaggaagaggaaggaaaggaaaaaacatttgaagagaaagagatggagaagcagaag accttgtaccagcaggccaggctgcatgccagaggagcagcggagatggtgctgcagatg atcagtgccagcaagggtcgactaggccccatggtgacttgcactctaaaactgggaatt tctattctcaatggaggcaatgtggctgttcagcagaaaatgctggactacctgaaagaa aaaagagatgctgggtttttcaaaagtttatctggactaatgcagtcttgcagtgtactg gacttgaatgcatttgagagacaaaaaaaggcagagagccttggaatggtgactgaagaa ggatcggtcaacgtgagtgagcggggttccaaagtactacaaaatgatgaatttacgaag gatttatttaggtttttgcagcttctgtgtgagggccacaataatgatttccaaaacttc ctgagaactcagacaggaaatacaactaccgtcaacattattattagcacagtggactac ctgctgcgcttacaggaatctataagtgatttctactggtattattctggaaaagacgtc atggatgagcacggacagcttaatttctccaaagctttggaagtggctaaacagatcttc aactcactcactgagtacattcaggggccttgtattgggaatcaacaaagtctggctcat agcaggttgtgggatgctgtggttggatttttgcatgtctttgctaacatgcaaatgaaa ttatcacaggattctagccagattgagctactaaaggaattgctagatttgcagaaggat atggtggtcatgatgttatctcttttggagggtaatgtggtgaatggtacaattggtaag cagatggttgacacattagtggaatcctcaagcaatgtggaaatgatcctcaagttcttt gacatgttcctgaaattgaaggatcttactacctctgacaactttaaagaatatgatcct gaagggaaaggaattatttctaagaaggagttccagaagtctatggagagtcaaaagcaa tacacacagtcggagattgagtttcttctttcttgtgctgaggccgatgaaaatgacatg ttcaactatgtggaatttgttgaacgcttccatgagcctgctaaggatattggcttcaat atggctgtactgctaaccaacctgtctgagcacatgccacatgactcacgtctagctacc ttcctagacctagctgagagtgtgctcagttattttgagccgtacttgggccgcatcgag atcatgggtggtgccaagcgaattgaacgagtctactttgagattagcgaatccagcaga gaacagtgggagaagcctcaggtgaaggagtccaaacggcagtttatctttgatgtggtc aatgagggaggtgagagtgagaaaatggagctatttgtgaacttttgcgaggacacaatc tttgagatgcagctggcttcccagatatccgaaccagacacagcagaacgacctgaagaa gaagacgaagaggagctccagagtctgttagaggaactggccgagggagaagatggctcc catgagtcagcttcggccttcactgttgcctgcacctctgttaagaagaaaatgtccaat tgccgccaaatgctaaccttcaagaacatgcgtaaacaatttaagaagttaaagaagctg accatcaaagaaataatcatagggttcttctccttattctggatgctcttcactgggttc ttcaaaagcattttcagtttaatctttggattcttccatatcatatggtcatctatgttt ggtggcgggcttgttgagggggctaaaaacatgaaggtaacagatatcttgggcaacatg cctgatcccacacagtttggaatccatggcgatgtgatggaaccagaaaaagctgagagt ggtgatttagttgtgtctatggaaatggttcaaatgactgctgcaggggaaaaactggag cctgatgccatcatagatctcataagtccacccacaaaaagagagggaaagcatggatct gagcctggattgggagatgtctcagagtttaagacagaagccagtcctcccatcgaaaaa aagaaaagtcagaaagtggctacagaggagtcagaacctgagaaagcagacacagaaaat cgtgaaaaggaggatatggccaaagaggaaaagcctgaagagcctgtagcagaggagaag ccagctccaagaaaacagcatggcgctccaaaggagcagcctccagcattaatggccagt gtctttgctggtctagaagtctataagacaaagatgctgaactacttggctcgaaatttc tacaaccttcgtttgcttgcattgtttgtggcatttgcaatcaacttcatcctactcttc tacaaggtgactggtgaagctgatgatgaagaagaggaagggctttggggtggagatgat gatgatgatgatgatgatgatgaaggtggaatggagttctatgtactccaggagaacact ggctatatggcacccactctgactttcttggctatactacataccataatttccctccta tgtgttgtgggatattactgcctcaaggttcctttagtggtgttcaagcgagagaaagag attgcaaggaaacttgaatttgatggcttatatatcactgaacagccttctgaggacgac atcaaaggacagtgggaccgtttggttattgctactccatcatttcctaataattattgg gacaaatttgtcaagaggaaggtcatcaataaatatggggatttgtatggtgcagagcgc attgctgagctccttggactggataagagtgcacttgacttcgaccccactgaggaagct gtggtaaaggaagcctctttggtgtcctggttgagctctattgacaccaagtactacatc tggaaaatgggagttgtcctgactgacaattctttcctctacctgatctggtacaccacc atgtctatactgggacattacaataacttcttctttgctgctcacttgttggatattgct atgggcttcaagacgctgagaaccatcttgtcctctgtaactcataatggcaagcagctg gtgttgactgtgggtctgctagcagttgttgtctatttatacactgtggtggctttcaac ttcttccgcaagttctacaacaagagtgaggatgaggatgagcctgacatgaagtgtgac gatatgatgacttgctacctattccacatgtatgtgggtgttagagctggtgggggcatt ggtgatgagattgaggacccagctggggacccttacgagatttaccgcattctcttcgac atcactttcttcttctttgtcatcgtcatcctgctggcaatcattcagggtttaatcatt gatgcctttggggagttgagagaccaacaggagcaagtgaaggaggacatggagacaaaa tgtttcatctgtgggattgggaatgactactttgacaccacaccccatggttttgagacc cataccttacaagagcacaacctagccaactatctattcttcctgatgtatctcattaac aaagatgagactgaacatacaggccaggagtcatatgtgtggaagatgtatcaagaaagg tgctgggacttcttccctgctggagactgcttccgcaagcaatatgaggaccagctgggc tag

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