Electrophorus electricus (electric eel): 113571324 Help Entry 113571324         CDS       T05787                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism eee  Electrophorus electricus (electric eel) Pathway eee04020   Calcium signaling pathway eee04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:eee00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     113571324    04020 Calcium signaling pathway     113571324  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:eee04040]     113571324 Ion channels [BR:eee04040]  Voltage-gated cation channels   Ryanodine receptor    113571324 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 Ago_Mid Motif Other DBs NCBI-GeneID:  113571324 NCBI-ProteinID:  XP_026855983 LinkDB All DBs Position Unknown AA seq 4881 aa AA seqDB search MAMAEGEGEDEIQFLRTDDEVVLQCVACIQKENRKFCLSAEGFGNRLCYLEPTSEAKYIP PDLCICNFVLEQSLSVRALQEMLAKTGQSNDAAHGGGHRTLLYGHAILLRHSLSGMYLTC LKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYL HLSLSNGSVQVDASFMQTLWNVHPTCSGSSVEEGYLLGGHVIRLFHGHDEVLTIPASDQS EEQQRIVNYESGKVGVKARSLWRLEPLRISWCGSHIRWGQPFRLRHLTTGQYLALSDDSG LLLQDREQSDTASTAFCFRASKEKLEQSPRRDIEGMGVAEIKYGDSLCFVLHVATGLWLS YQAPDVKSARLGSLKRRAYLHAEGHMDDGFTLQRCQHEESRAARIIRNTTRLFSRFIRDL DGLTGKNRMAVLLPIQEVLQTLKDLITYFQLPDAELEHEEKQIKLRSLKNRQNLFKQEGM LTLVSDCIDRLSVYNSAAHFSECAGEEAGLAWKDILHLLYALLAALIRGNRNNCTQFSHN LDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIIALLYKHGRNHKILDVL CSLCVCNGVAVRANQNLICDHLLPKRDLLLQTRLVNDVQSMRPNIFLGVRESSAQYKKWY FELMIDQVEHFVTSEPSHLRVGWASTKGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWS GRIPRRVASVNQHILTSDDVVSCCLDLTAPSISFRINGQPVQGMFESFNTDGLFFPVVSF SAGVRVRFLLGGRHGEFKFLPPSGYAPCYEALLPKEKMRVEPVKEYKRDMDGVRDLLGTT QFLSQASFIPTPVDTSQIVMPPHLEKVRDRLAENIHELWAMNKIEMGWSYGKMRDDNKRQ HPCLVDFSKLPETERNYNLQMSTETLKTLLAVGCHIVQVHVSIEEELQKVKLPKNYMMSN GYKPTPLDLSDVKLTSGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDVKSKRNPRLVP YSLLDERTKKSNRDSLREAIRTLIGYGYNIEPPDQEGGHVVERLSIDKIRFFRLERTYAV RKGKWYFEFETVTGGDMRVGWARPGLRPDVELGTDDQAYVFDGYRGHRLHQGSRLFGRCW RAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFTDFETEDGFIPVCSLGLSQVGRMN LGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPKDHCHIEVTRIDGT VDGPPCLKVTHKTFGTQNSNADMVFLRLSMPVEFHPTIRSSASTDVNGVHDEEPLKLRHR HPVKSLKHTEDMRRSDYSSITSYYHSVRVFAGQDPSCVWVGWVTPDYHYYSNLFNLSKNR TVTVTLGDERGRVHESVKRSNCYMVWGGDIFSVNHSSSRSNVDLEIGCLIDLATGLVAFI VNGKELATSYQVEPNTKLFPAVFVRPTSPNLFQFELTKIKNTMPLSSAIFKSEHKNPVPQ CPPRLDVQTIKAVLWSRMPNTFLKVETARVSERHGWQVQCLEPLQMLAVHIPEENRCVDI MELSEQEDLRKFHYHTLKLYCALCALGNTRIAHALCSHLDQSQLLYTIDNQYLSGMLREG FYNVLISIHLETAKAARLMMNNEFIIPVTAETRSIRLFPDASKRHQPPGVGLSTSLKPRL SFAPPCFITTKRDQHLYSPEIPLDVLREKAISMLTEAVQGGGDHIRDPVGGSVEYQFVPI LRLICTLLTMGVLASQDVHKILLLIEPSVFGEQREDMVGEAMEKEGVTGAEEKAVEAGEE EAKDTKPPIRGLLQKKLPESVKRQMCELLHYFCDCELRHRIEAIVSFSDGFVSKLQYNQK FRYNELMQALNMSAAVTAKKTKEFRSPPQEQINMLLNFSMGEDCPCPEDIQDELYDFHDE LRLHCGIPMEEEEEEQDTSIKGRLLALVYKIKGQPHKERPLEKEQAAPSNLKELISQTMV SWAQESHIQDPELVRVMFSLLRRQYDSIGELLRAMRKSYTISAASVHDTIHLLASLGQIR SLLSVRMGEEEERLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGGKSQEI AFPNMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPSMRGSTPLDVAASSV MDNNSLALALEEPDLDKVVTYLAGCGLQSCPMLLSKGYPDIGWNPIEGERYLSFLRFAVF VNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISEMPALDLPSSTQG LTSDASTEDGEEDEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEAVRIRAILRSL VPIEDLVGIISIPLQMPVVNKDGSVTEPDMSASFCPDHKAPMVLFLDRVYGIEDQSFLLH LLEVGFLSDLRAAASLDTDTLRTTETALAMNRYIGTAMLPLLTRCAPHFASTEHHATLID STLHTIYRLSKGSALTKAQRDAIEECLLAVCRHLRPSMLQQLLRRLVFDVPLLSEYCKMA LKLLTNHYEQNWKYYCLPSGWGSYGMASEEELLLTKKIFWGIFDSLSQKKYDQELFKMAM PCLSALAGALPPDYIDCSICTALEKPVSVDAQGSFDPRPISTANISLPEKLDYIANKYAE HSHEKWSSEKVVLGWRYGDAMDEKGRTHPMLRSYKSLTEKVFRTTVHHHESLRSMLAMGW NIDRTKEGETMFQQREKEKMRNISQTSQGSGFNPSPVDMSNVLLSRELQAMVEVLAENYH NIWAKRKKNDLGTKGGGTHPLLVPYDTLTAKEKSRDREKAQELFRFLQINGYAITRGIKD MEQDSFSMEKRFAYKFLRKLLKYVDSAQEFIAHLEAMASSGKNDRSPHEQEIKFFAKVLL PLIDQYFKNHSLYFLSSPSKNLSSSGYASNKEKEMVTSLFCKLAALVRHRISLFGSDSAT MVSCLHILAHTLDTRTVMKSGSELVKAGLRTFFENAAEDLEKTLENLKLGKFTHSRSQMK GVSQNINYTTVALLPILTALFEHITEHQFGTDLLLDDVQVSCYRILTSLYSLGTGKNIYV ERQLPALGECLATLAGAMPVAFLEPDLNSYNPCSVFNTKTARERAILGMPDAVEEMCTEV PRLDRLMKDINDMSESGARYTDMPHVIEVVLPMLCNYLSYWWERGPESHPASTGTACSTT VTSEHLSVILGNILKILNSNLGIDEASWMKRIAVYAQPIISKARADLLKTHFLPTLEKLK KKTVKVVVEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKE PDADSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDTKTKMSKLFLPKV GGQDQERKHKKRRGELYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKMRYGLKDTD EEVKEHLKQNMHLQEKSEDPAVRWQLNLYKDVVVKNEGPPDPQRTVERLQTISAAVFHLE QVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHKTNAYFLNAYRHFWLEEMHG SADYDSLLSMLTRTQRKGEEEEEEVAEVQPDPLHQLILHFSHNALTERSSLEEDPLYIAY ADMMAKSCAEDEEEEEEGKEKTFEEKEMEKQKTLYQQARLHDRGAAEMVLQMISASKGRL GAMVTFTLKLGISILNGGNILVQQKMLDYLKDKRDAGFFKSLSGLMQSCSVLDLNAFERH NKAEGLGMVTEEGSINVRERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNT TTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDEAGQHNFSKALAVAKQIFNSLTEYIQ GPCVGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDMIVMLLSL LEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTSSDSFKEHDSESKGVISK REFQKSMENQKQYSQSEIEFLLSCAEADENDMFNYVEFVKRFHEPAKDIGFNVAVLLTNL SEHMPHDSRLATFLNLAESVLNYFESFLGRIEIMGGAKRIERVYFEISESSRTQWEKPQV KESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASLISEPDATERAEEDEDYWQSV GEEPEEEEEECTRESSSAFAAACVSARRSLCGLQKLLTLRSMRRQYKKFRKMSMRETVRG FFSFFWMIFTGLLHFLRNLVWGFFHILWSTMFGGGLVEGAKNMKVTDILGNMPDPTQFGI HGDVLETEKLEASEASLVAEIGQMVQGEQGDMDLMSELLIIQPKKEGGKHGTEPGLGDVS EVVGADSPSLVAAVRQKKAQEAASKKAVDTESKTEFEKADTEDGEKKDQDKGKEESTIEL PSDEEKRPTKRRHGQKKEQPEAFMASFFAGLDIYQTKILNYLARNFYNLRFLALFVAFAI NFILLFYKVTGEESEEVDPWTRRGDEEEEGVVEYFVLQESTGYMAPTLRFLAVLHTIISC LCVLGYYYLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINTPSFPNNY WDKFIKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEETVSKAASLASWLSSIDTKYH IWKMGVVFTDNSFLYLVWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQ LVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGG IGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMET KCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQE RCWDFFPAGDCFRKQYEDQLG NT seq 14646 nt NT seq  +upstreamnt  +downstreamnt atggccatggctgaaggcgaaggggaagatgagatacagttcttacggacagatgatgag gtggtcctgcagtgtgtggcgtgcatccagaaggagaatcgcaagttctgcctctctgct gagggattcggcaatcggctatgctacctggaacccacctcagaggccaagtatattcct ccagacctgtgcatctgtaactttgtgttggagcagtcactttctgtaagggcactgcag gagatgctggccaaaactgggcaaagtaatgatgcagcccatggaggcggacacagaaca ctgctgtatggacacgccatcctcctccgacactccctcagtggaatgtacctgacttgt ctgaagacgtccaggtctctgacagataagttgtcttttgatgtgggccttcaggaggac tccacaggtgaggcgtgttggtggactatccaccctgcctctaagcagagatccgaaggg gagaaagtacgtatcggtgatgacctgatcctcgtcagtgtgtcatctgaacgctacctt cacctgtccctctctaatggcagtgttcaggtagatgcgtccttcatgcagacactgtgg aatgtccatccaacatgctcgggcagcagcgtggaggaaggatatctccttggtggtcat gtgatacgcttgttccatgggcatgatgaggtcctgacgatcccagcttcagatcagagc gaagagcagcagagaatagtcaactacgagtcaggcaaagtgggagtcaaggcccggtct ctatggagattggaacctctacggatcagttggtgtggcagtcacatccgctgggggcag ccgttccgtctacgccatctcaccactggccagtacctggccctgtctgatgactcaggc ctactactgcaggacagagagcagtcggacacggcctccaccgccttctgcttccgtgcc tccaaggagaagctggagcagagccccaggcgggacatagagggcatgggtgtggctgag atcaagtacggcgactcgctctgcttcgtcctgcacgtagctacgggcctatggctctcc taccaggcacctgacgtgaagtctgcccgtctgggctccctcaagagacgagcctacctc cacgcagaagggcacatggacgatggcttcaccctccagcgctgtcagcatgaggagtca cgcgccgcccgcatcatacggaacacaaccagactcttcagccgcttcatcagggatctg gacgggctaactgggaagaaccgcatggctgtgctgctccccatccaggaagttctccag acactcaaggacctcatcacctacttccagctacccgatgctgaactggagcatgaggag aagcagattaagcttcgatcgctcaagaaccggcagaacctctttaaacaggaggggatg ctgacgctggtgtcagactgcatcgatcgactgagcgtgtacaatagcgcggcacacttc agtgagtgtgcgggggaggaggcaggactggcctggaaggacattcttcaccttctctat gcgctgctggctgctctgattcgagggaacaggaacaattgcacacagttctcccacaac ctggactggttggtcagtaagctggagagactggagtcatcctcaggaattctcgaggtc ctgcactgcatcctgattgagagcccggaggcgctcaatatcatccagagagggcacatc aagtccatcatcgcgctgctgtacaaacatggtcgcaaccacaagatcctcgatgtgctc tgttctctctgtgtctgcaatggagtagcagtaagagccaatcaaaacctcatctgtgat cacttgctcccaaagagagacctgttactccagacaagactggtcaatgatgtccaaagt atgagacccaacatctttctgggcgttagggaaagttctgctcagtataagaagtggtac tttgaactgatgatcgaccaggtggagcactttgtgaccagcgagccctctcacctgcgg gtggggtgggcctccaccaaaggctatgccccctaccccggtggtggagaaggctggggg ggcaatggggttggggatgacctctattcctacggcttcgatggacttcacttgtggtca gggaggatccctcgacgcgtggcctcggtgaaccagcacatactcacatcagacgacgtg gtcagctgctgcctagacctgactgcccccagcatttccttcaggattaatgggcagcct gtgcagggcatgttcgagagcttcaacacggacggcctcttcttccccgtggtcagcttc tcagccggggtcagggtgcgcttcctcctgggtggtcgtcacggagaattcaagttcttg ccgccgtcaggctatgccccgtgttacgaggctcttctgcccaaggagaagatgcgtgtg gagcctgtgaaggagtacaagagggacatggacggagtgagggacctgctgggcaccaca cagttcctttcacaggcgtcattcatacccacacccgtggacacctctcagattgtcatg cctcctcacctggagaaagtgcgtgacagactggctgaaaacatccacgagctctgggcc atgaacaagatcgaaatgggctggtcttacggcaagatgagggatgataataagagacag catccctgccttgtggatttctccaaactacctgaaacagagaggaattacaacctgcag atgtcaacggagaccttgaagaccctgctggcagtgggatgccacattgttcaggtccat gtcagcattgaggaagagctacagaaagtcaaactccccaagaactacatgatgtcaaat ggctacaaacccactccgctggacttgtctgacgtgaagctgacctctggccaagagctc ctggtggacaagcttgcggagaacgctcacaacgtttgggccaaagaccggatcaagcag ggctggacctatggcattcagcaggatgtgaaaagcaagcgtaatcctcgcctggtgccg tattctttgcttgatgagcgcacaaagaagtcaaaccgggacagtctccgtgaggccatc cgcacgcttattggatatggctataacattgagcctcctgaccaggagggtggccatgtt gtggagaggctgagcatcgacaagatccgcttcttccgcttggagaggacatacgcagtg agaaagggcaagtggtactttgagttcgagacagtgaccggcggagacatgagggtgggc tgggctcggccgggcctgcggcccgatgtggagctgggcactgatgaccaggcttacgtc ttcgatggctacaggggccaccgcctccaccagggtagccggctgtttggccgctgctgg cgcgctggggacgtggtgggctgcatgatcaacatggaggacaagtccatgatcttcacg ctcaatggagagatccttatcaccaacaagggctcagagctttgtttcactgactttgag actgaggatggctttattccggtctgcagcttggggctttcacaggtgggtcggatgaac ctgggcaaggatgccagcacgttcaagtactacaccatgtgtggcctgcaggagggcttc gaacctttcgctgtcaacatgaacagagaagtcaccatgtggttcagcaagcgtttgcct acttttgtcaatgttccaaaggatcactgtcatattgaggttacacggatcgacggcact gtggacggcccgccttgtctgaaagtgacacacaagacatttggaacacagaacagcaat gctgacatggtttttctccgcctgagcatgcctgtggagttccaccccaccatcaggagc agcgccagcactgatgtgaacggcgtgcacgatgaggagccgctcaaactccgacatagg catcctgtgaaatctctgaaacatacagaggacatgaggagaagtgactatagtagcata acctcttactaccactcggtcagggtgtttgctggtcaagatccctcctgcgtgtgggtt ggctgggtcacccctgactaccattactacagtaacctgttcaacctcagcaagaaccgg actgtgaccgttacactgggggacgagcgaggccgggtccatgagagtgtaaagaggagt aactgctatatggtgtggggaggggacatctttagtgtgaaccattcctccagccgcagt aatgtggatttagagatcggttgcctaatcgatttggctactggcttggtggcctttatt gtcaatggcaaagagctggcaacctcatatcaggtggaacccaacacaaagcttttccct gctgtgtttgtacgacccaccagtccgaatctgttccagtttgagctaaccaagatcaag aacaccatgcctttatcatcagcaatcttcaagagcgagcacaagaacccggtcccgcag tgcccaccgcggctggacgtccagaccatcaaggcagtgctgtggagccggatgcccaac actttcctgaaggtggaaacagcccgcgtgagcgagaggcatggctggcaggtgcagtgc ctggaacccctgcagatgctggccgtgcatataccagaggagaaccggtgtgtggacatc atggagctctctgagcaggaagacctccgcaagttccattaccacacactaaagctctat tgcgcactctgtgccctcggcaacactcgcatagcccacgcactttgtagccacctggac caatcccagctcctctacaccattgacaaccaatacttgtcggggatgctgcgcgaaggg ttctacaacgtgctcatcagcatccacctggagacagccaaagctgccagactcatgatg aacaatgagttcatcatcccagtcactgcagagacccgtagcatccggctttttccggat gcctccaagcgccaccagcctccgggtgtgggactgagcacatccctaaaacccagactc agttttgctccaccttgcttcatcaccaccaaacgtgaccagcacctctacagtcctgaa atccccttggatgttctgagggagaaagcaattagcatgctaacagaggctgtccaagga ggaggggaccacatccgggacccggttgggggcagtgtggagtaccagtttgtgcccatt ctacggctcatttgcacactactgaccatgggtgtgctagccagtcaggacgttcacaag atcctgctcctgattgagccaagtgtatttggagagcagagggaggacatggtgggtgag gccatggagaaggagggtgtgacgggggcagaggagaaggccgtggaggccggggaggag gaagccaaagacacaaagccaccaatcagaggtctgctgcagaagaagctgccagagtca gtcaaacggcagatgtgtgaacttcttcactacttctgtgactgtgagctaagacaccgc attgaagccatcgtgtccttctctgatggcttcgtatcaaagctacaatacaaccagaag ttccgatacaacgagctaatgcaagctctcaacatgtcagctgctgtcaccgccaagaag accaaagagttccggtcacctccgcaggagcagatcaacatgttgctgaacttcagtatg ggagaggactgtccatgcccggaagacatacaggacgagctctatgactttcatgatgag ctccgtctacactgtggtattcctatggaagaggaggaagaggagcaggacacatccatc aaaggccgcctgctagccctggtctacaagatcaagggacagccacacaaagagagaccg ctggagaaagagcaagccgccccatccaacctgaaggagctgatctcccagaccatggtg agctgggctcaggagagccacatccaggacccggagctggtgcgtgtcatgttcagcctg ctgcgtcggcagtacgacagcattggtgagctgctgcgtgccatgcgtaagagctacacc atcagcgccgcctctgtgcacgacacaatccacctgctggcttcgctgggccagatccgc tcactactcagcgtgcgcatgggtgaggaggaggagcggctcatgatcgatggcctgggt gacatcatgaacaacaaggtgttctaccagcaccccaacctgatgagggtactgggcatg cacgagactgtaatggaagttatggtgaacgtattggggggtggcaaatctcaggaaatt gcctttcctaacatggtggcaagctgctgccgattcctgtgctacttctgccgaatcagc cgccagaaccagaaggccatgtttgaccacctgagctacctgctggagaacagcagtgtg gggctggcgtctccatccatgagaggctccacacctctggatgtagctgcttcctctgtg atggacaataacagtcttgcacttgcactcgaggagcccgaccttgacaaggtggtcacc tatctagcaggatgtggactgcagagctgtcccatgctgctctccaaaggctatccggac ataggctggaaccccatcgagggggagcgctatctctccttcctgcgctttgctgtcttc gtcaatggtgagagcgtggaggagaactctagcgtggtggtgaagctgttgattcgtcga cctgagtgctttggccccgccctccgtggagagggcgggaatggactgctggcggccatg aaagaggccattaaaatatcggagatgccggcactggacctgcccagcagcacccagggt ctcacatcagatgcgtccactgaggatggtgaggaggatgaggtcgtccacatgggcaat gccatcatgtcgttctactctgccctcatcgacctgctgggacgctgtgcgcctgagatg cacctgattaataagggcaaaggggaggctgttcgaatccgtgccatcctgcgttctctt gtgcccatcgaagacctggttggcatcatcagcatcccgctccaaatgcctgtcgttaat aaagatggcagtgtgactgagcctgacatgtctgcctctttctgcccggaccacaaggca cccatggtgttgtttttggaccgggtttatggcatagaggaccagagcttccttctgcac ctgctggaggtgggcttcctctccgacctgcgtgccgcagcttctctggacacggacaca ctgaggaccactgagacagctctagcaatgaaccgctacattggcacagccatgctgccg ctgctcactcgctgtgccccccactttgccagcactgagcaccatgccacgctcatcgac tccaccctccacaccatctaccggctgtccaagggctctgcactcaccaaagctcagaga gacgccattgaggaatgcctgcttgctgtctgtaggcatttgagaccctccatgcttcag cagctgctccgtcgcctggtgtttgacgtgcctctgctgtctgagtactgtaaaatggct ctcaagcttttaacaaaccactatgagcagaactggaagtactactgccttccatctggt tggggcagctatggtatggcttctgaggaagagctgctcctcaccaagaagatcttctgg gggatcttcgattcactctcccaaaagaagtatgaccaggagctatttaagatggccatg ccatgtctgagtgctctagctggtgcgctgcctccagactacattgactgctctatctgc actgcactggagaagccagtctcagtggatgcacagggcagcttcgaccctaggcccatc agcaccgccaacatctccctcccagagaagctggattacattgctaataagtatgctgag cactctcatgaaaaatggtcctcggagaaggtagttctgggctggaggtatggagatgcc atggatgagaaaggaaggactcatcccatgctgagatcttataagtcactcacagaaaag gtattcagaacaacagtacatcatcatgagtctttgaggagtatgctagccatgggctgg aacattgacaggaccaaagagggagaaaccatgtttcagcaacgggagaaagagaaaatg cgtaacatttcccaaacctctcagggcagtggcttcaacccgagcccagtcgacatgagc aacgtgctgctgtcccgagaactgcaggctatggtggaggtgctggctgaaaactaccac aatatttgggccaaaaggaaaaagaatgacttgggcacgaaaggtggaggaacacatcct ttgttggtgccatatgacacccttacagccaaagagaaatccagagaccgagagaaggca caggaactgttccgcttcctgcagattaatggctatgccattactagaggtataaaagac atggagcaggactctttctcaatggaaaaaaggtttgcctataaattcctcaggaagctg ctgaagtatgtggattctgcacaggagttcattgctcacctggaggccatggctagcagt ggaaagaatgacaggtcacctcatgagcaagaaatcaagttctttgccaaggttcttctt cctctgatagaccagtacttcaagaaccactctctctatttcctgtcctcacccagcaag aacctaagcagcagtggctatgcttccaacaaggagaaagagatggttaccagccttttc tgtaagctggcagctcttgttagacacaggatctctctctttggaagcgattcagccaca atggtgagctgccttcatatcctggcacacacacttgacaccaggacagtgatgaagtca ggctcagagctggtgaaggcgggcctaagaacattctttgagaacgcagcggaggactta gagaagaccctagagaacctgaagctaggcaagttcacgcactcccgcagccagatgaag ggtgtgtcgcagaacatcaactacactacagtggccctactacccatcctcactgccctg ttcgagcacatcaccgagcaccagttcggcacagacctgctgctggatgatgtccaggtg tcatgctataggatcttgaccagcctgtactcactgggaactggcaagaacatctacgtg gaaagacagcttccggctctgggggagtgtttggccacccttgctggagccatgccagta gcatttctggagcctgatctcaactcatacaacccctgctctgtgttcaacaccaagaca gcgcgggaacgtgccatccttggcatgccagacgccgtggaagagatgtgtactgaggtg cctcgcctggaccgcctgatgaaggacatcaacgacatgtccgagtcgggcgcccgctat acagacatgccccatgtcattgaggtggtgctgccaatgctgtgcaactacttgtcctac tggtgggagagagggcctgagagccaccctgcaagcacaggcaccgcgtgcagcaccacc gtcacctctgagcacctcagtgtcatcctgggcaatatcctaaagatcctcaacagtaac ctaggcatcgacgaggcttcttggatgaagaggatagcagtgtatgcccagccaattatc agtaaggcaagggcagaccttttgaagacgcatttcctgcctacactggaaaagctgaag aagaagactgtgaaggtagtggtggaggaggagcttctaaaagctgacagcaagggtgac acccaggaggcggagcttctcatcctggatgagtttgcagtactgtgcagggatctgtat gccttctatcccatgctcatccgctatgtggataacaataggtcacgctggctgaaagag cctgatgctgactccaatgagctctttaggatggtggcagaaatcttcatcctctggtgc aagtcacataactttaagagagaggagcagaactttgtcgtgcagaacgagatcaacaac ctctccttcctcaccggggacaccaagaccaagatgtccaagttgtttctgccgaaggta ggaggacaggaccaagagaggaagcacaagaagcgacgtggcgagttatactccattcag acctccctcatagtggccgccctgaagaagatgctgcccattggcctcaacatgtgcacg cctggtgaccaggagctcatctcattggctaagatgcgctacggcctgaaagatacagat gaagaggtaaaggagcacttgaaacagaatatgcacctgcaagagaaatcggaggaccct gctgtgaggtggcagcttaacctgtataaggacgtagtggtgaagaacgaggggcctccc gacccacagcgaacagtggagcgcctccagaccatctcagctgctgtgttccacctcgag caggtggagcagccgttgaggtctaagaagtgtgtgtggcaaaagctactgtccaaacaa cggaagcgggcagtagtcgcctgcttccgcatggcccccctgtacaacctacccaggcac aaaactaatgcctacttcctgaatgcctaccgacacttttggctggaagaaatgcatggg agtgcagattatgacagtctgctctccatgctaacgaggacacagcgtaaaggggaggag gaggaggaggaggtagctgaagtgcagccagaccctcttcatcagctcattctgcacttt agtcataatgctctgacagagagaagctcactagaagaggatccactgtacatagcatat gcagacatgatggccaagagctgtgctgaagatgaagaagaggaggaagaaggaaaagaa aaaacttttgaggaaaaggagatggaaaaacagaagacactgtatcagcaggcaagatta catgacagaggggctgctgagatggttttacagatgataagtgccagcaaaggtcgacta ggtgccatggtaaccttcactctcaagttgggtatctccattctcaacgggggcaacatt ttagtccagcagaaaatgctggactatctaaaggacaagcgagatgctggctttttcaag agtctgtctgggctgatgcagtcatgcagtgtgctggacctgaatgcatttgagagacat aacaaagctgaaggactgggcatggtaactgaggaaggctcaatcaacgtgagggagcgg ggttccaaggtgctccagaatgatgagttcactaaagaccttttcaggttcttgcagcta ctctgcgagggccacaacaatgacttccagaactttctgagaactcagactggaaacaca actactgttaatattattataagcacagtggactatcttcttcgactacaggagtccatc agtgatttttactggtattattcgggcaaagatgtcatggatgaggctggacagcataat ttctccaaggccttggctgtagccaagcagatctttaattccctcactgaatatatccag ggtccatgtgtcggcaaccagcagagtctggcccacagcaggttatgggatgcagtggta gggtttctgcacgtctttgccaacatgcagatgaaactgtcacaggactccagccagatt gagttactgaaggagctgctggatctgcagaaggacatgatagtcatgttgctttccctt ctggaaggtaatgttgtaaatggaaccatcggcaaacagatggtggacaccttggtggag tcctccagcaatgtggagatgatcctcaaatttttcgatatgtttctcaaactcaaggac ctcacctcttctgacagtttcaaagagcatgactctgaaagcaagggagtcatttccaaa agagaattccagaagtcaatggaaaaccagaagcagtactctcagtctgagattgagttc ctgctttcttgtgctgaagcagatgagaatgacatgttcaactatgtggagtttgtgaag cgtttccatgagccagccaaggacattggtttcaatgtagccgtattgctcaccaacctg tccgaacacatgccccacgattcccgtctggccaccttcctgaacctggctgagagtgtc cttaattattttgagtcattcctaggccgcattgagatcatgggtggtgccaagcgaatt gagagggtctacttcgagatcagcgagtccagcaggacccagtgggagaagccacaagtc aaggagtccaagcggcaattcatattcgatgtagtcaatgaaggcggtgagtcagagaag atggagctctttgtcaacttctgcgaggacaccattttcgagatgcagctggcctcactc atctctgagccagacgccaccgagcgggcagaggaggacgaggattactggcagagtgtg ggtgaagagcctgaggaggaggaggaggagtgcacacgggagtcctcctcagcatttgct gcagcctgtgtctcagccaggaggagtctctgtggcctgcagaagctgctcaccctgcgg agcatgcgaaggcagtacaagaagttccggaagatgagcatgagggagacagtacgtggg ttcttctcctttttctggatgatcttcacggggctgctccacttccttcgcaacctcgtg tggggcttcttccacatactgtggtccaccatgtttggcgggggcctggtggaaggcgca aagaacatgaaggtgacagacatcctcggcaacatgcctgaccccacgcagttcggcatc catggggacgtcctggagacagagaagctggaggcgagtgaggcttccttggtggcagag atcggccaaatggtgcagggcgagcagggcgacatggacctcatgtcggagctgctgatc atccagcccaagaaagaggggggaaagcatgggactgagcctggcctgggagatgtctct gaagtggttggggcagactctccatccctagttgctgctgtgcggcagaaaaaggcccag gaagctgcaagcaagaaggcagtagacactgaatcaaaaacagaatttgaaaaagcagac acagaggatggcgagaagaaagaccaagacaaaggcaaggaagagtctaccatcgaactc ccatcagatgaagagaagaggccaactaagaggagacatggacagaagaaggaacagcca gaggccttcatggccagcttttttgctggcctggacatctaccagaccaagattttaaat tacctggcacgaaacttctacaacctacgattcctggccctgtttgtggcatttgccatc aacttcatcctgcttttctataaggtcactggtgaggagtctgaggaggtggacccttgg accaggagaggtgatgaggaagaggaaggtgttgtggagtattttgtgctacaggagagc actggctatatggcacctacgttacgctttctagctgtactacacactatcatctcctgc ctctgtgtgctggggtactactatctgaaggtgcccctggtggtatttaagcgggagaag gaaattgccagaaaacttgaatttgatggtctttatatcactgagcagccttctgatgat gacatcaaagggcaatgggacagacttgtgattaatacgccatccttcccaaataactac tgggataagttcatcaaacgcaaggtgatcaataaatatggtgacttgtatggggcggag cggattgctgagctgctcggtctggacaagagtgctctggacttcaaccccactgaggag actgtaagcaaagcggcctccttggcatcctggttaagttctatcgacaccaaatatcat atctggaaaatgggcgtggtgttcacagacaattctttcctgtatttagtgtggtacacc accatgtccgtcctcggccactacaacaacttcttctttgctgctcacctgctggacatc gccatgggcttcaagacactgaggaccatcctctcctcagtcacccacaatggcaaacag ctggtactaactgtaggactgctggctgtagtagtctatctttacactgtagtggccttc aacttcttccgaaagttctacaacaagagtgaagacgaggacgagccagacatgaaatgt gacgatatgatgacctgttatctgttccacatgtatgtgggtgtgcgtgccggtggtgga ataggggatgagatcgaggacccagctggagacccctacgaactttaccgcatcctcttc gacatcaccttcttcttctttgtcatcgtcatcctcctggccatcatacagggtttgata attgatgcatttggagaattgagagaccagcaggagcaggtcaaagaagacatggagacc aaatgcttcatctgtggcattggaaatgactactttgacaccactccacatggctttgag acacacactttacaagagcacaacttggccaactacctgttctttctcatgtatctcatc aacaaggatgagactgagcacacaggccaggagtcctacgtgtggaagatgtaccaggag cggtgctgggacttcttcccggctggagactgcttccgcaagcagtacgaagaccagctg ggctag

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