KEGG   Epinephelus fuscoguttatus (brown-marbled grouper): 125894060
Entry
125894060         CDS       T08419                                 
Symbol
wnk2
Name
(RefSeq) serine/threonine-protein kinase WNK2 isoform X1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
efo  Epinephelus fuscoguttatus (brown-marbled grouper)
Brite
KEGG Orthology (KO) [BR:efo00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:efo01001]
    125894060 (wnk2)
   01009 Protein phosphatases and associated proteins [BR:efo01009]
    125894060 (wnk2)
Enzymes [BR:efo01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     125894060 (wnk2)
Protein kinases [BR:efo01001]
 Serine/threonine kinases: Other
  Wnk family
   125894060 (wnk2)
Protein phosphatases and associated proteins [BR:efo01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     125894060 (wnk2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C
Other DBs
NCBI-GeneID: 125894060
NCBI-ProteinID: XP_049441125
LinkDB
Position
LG1:complement(25835398..25873960)
AA seq 2311 aa
MDSADQSSKDPPLGSTFSSAPNLDSDINANARRPVYQNGTDHNVNIHIAALRGASDPSAY
PSTDYPALVRQRFIRRSLWVSDTDEQQPVDTPECVNSSPVPHIDLRTIVDRSRTRVLHGA
RLGLNETSDTESQVGLKDSVTESVSAEEVKGDKREAEPKVEVTPSDVTGKAGSDENEEEP
GMKAVSTSPGGRFLKFDIELGRGSFKTVYKGLDTDTWVEVAWCELQERKLSKAERQRFKE
EAEMLKALQHPNIVRFYDFWESPVKGKKCIVLVTELMTSGTLKTYLKRFKVMKPKVLRSW
CRQILKGLHFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTP
EFMAPEMYEEHYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGVKPASYSKV
SDPEIKEIIGECICHRREERYSIKDLLNHAFFAEDTGVRVELNEDDDGKKSSIALKLWVE
DTKKLKGKYKDTGAIEFSFDLVNEVPEVVAQEMVESGFFLDCDVKIVGKSIRDRVALIKW
RRERTFSSANGDVAVKKPQQNLLQVPGAVVPQAPTLVTTDYEEQEGEQQTLICTVPVTMT
ATSDSGVSSTMQLDDLNNQQNGTYQSLPEPISSAHVIYSPPDPQLHQGPYQQPTAQASHE
NYTQASTPLHQGAYQQPAGQLHPGAYHQPAAQLHQGPYQSQTTVSAPATPAPIVHQSRQT
AQSFPAAAPTLQPQLTAQSSQEQCPLQPAAVLPQLLSADQPTTHLSPPDISTSFPQSVSS
APPPLLPLQISTQFPSPYPVTQTGGLMPSPFPPAPLPCAYSSSGPSTSSSHFSPSPHHPS
LPLTPHAALPSVPSLSTPQTPLSTPQHVPSVALPIPLLAMSSAVSQQKGSPFTSQTNLGS
FHTTHPLPFSQVQPTPYPAPYPEQELSQPPFQVQMIAPQGNLGDFPLLAPAHPVLPTPLW
GSGVDAETSAASRDLTVAPTVPASVPAPVSDPASISATAQAETQASAQTPASTSVSAPTS
APIQVPTAAQAISSVPVQAPVSASGLAFESPKGSSTSSDTSSATGKPKLSVPGLGSAPIP
VTLPAPAPVAASVPAPVLQPAGIQTAVSVSECASLATTQQNLESTSASSTLQQEPCGEDV
LQDKPVSLRSYTYDSLNSDVASGKETSDGYDSLASGGKGDGKPRKHHRKSARTRSRQEKT
SKPKLSMLNVCNTGDKMVECQLETHNHKMVTFKFDLDGDAPEEIATYMVENGFILLLEKE
IFIDQLKDIVDKAEDMLNEDMEGERATALSCSPEQGQISEGLVGESQQPGASQPVYQQNV
LHTGKRWFIICPVEETPTSSQETPSDGTATQSPGSSATTQPADTGTARPSTSREEGSSST
MSGGSGGFTYDVYGFCSPPIMSNTDPLLLATLSPPVSAPPTLQSVTSVEPAGGSVQPSVH
QAQPARAQTLPPSSPHTSFPVDESRGSPLGSISPIDSAQQMPDVTCPVSVADEVPCCPLV
MPLSLDVSGLQSGSPLTPLPLQEPGSAKEPLSVSYTSSARSEHPQQPVVLHQPFSSVGGT
KVSSLPQSPAPSQHGAGPGESDTEGRLGRGGFVDSTIKTLDEKLRNLLYQEYAPMYPSGS
AAETPGSGTEYIQSPPGPDSATGGSGNSTPGPMGEGRYRAGEQLPQIPERMDSLSTLSDS
AVCASLSRRHVPNSASCSGTRGRFKIISVPPEVANRRDVKQRSWSSAASPAHPTGYSEDH
VQAETMTASTTIGRFSVVSTEDDITQRTRCSRYSAPPDFYLDTPPSMAKRGSLPRANTSN
SVSVDVTVHARFLSSDSGAESSPAKLTPATPSQHTRSERRGSDLMKRAVAFLRRSGRSSS
VQSSDSPSRHGGVHGSAYASSDNDSEMEDSDMKKELQRLREKHLREISELQAHQRGEVEL
LYRRLGKAPPSGLGLSHVAPHAGRRKRSGKHRLKPGKLLSPLVQQFRNVTTKTCDSSKSS
TAAGTGEPTVSLNGSPAKRPFPTHGRARSCTSHLPSSTTEPVQTQQPCSLKGSLSSDNIY
AGLHGDGTSTHAPPGQGWSNYPQTSERVTYKSSSKPRARFLSGPVSLSIWTTLKRLCLGK
ERGSRSGAGPGAFNQPQQQPPGATPPSHQPVMGLAQAQANNSNNKTGTYTGSSMSANENN
LPEDLQRLMEDWAQEVLIVSHRPRTNSLSISGQQLWNQVVPQTRGRLDSASDVSWTVPGP
EACNRPLSWPDSPGSTVMTSPSMGPRPSYQLHSSAPFRALPSPLSVSQWPGLLSPLPSGV
FAFPAVPSAQDAPSPILAPSYQPSDPKARTL
NT seq 6936 nt   +upstreamnt  +downstreamnt
atggattcggcggatcagtcgagcaaagatccgccacttggatccacgttttcctcagca
cctaatttagactcggacattaatgcaaatgcacgtaggcctgtttaccagaatgggaca
gaccacaatgtcaacatccacatcgcagctctgcgaggagcgagtgaccccagcgcgtac
ccgtccacagactacccggcgctggtgcgccagaggttcatccggcggagtttgtgggtg
tcagacaccgacgagcagcagccggtggacacaccggagtgtgtcaacagcagcccggtg
ccacacattgacctgcggaccatcgttgatcggagtcggacccgggttctgcacggagcc
cgcctgggcctcaatgagacctcggacacagagagccaggtggggctgaaggacagcgtt
acagagagtgtgagcgctgaggaggtgaaaggagacaagagggaagccgagccaaaggta
gaggttacgccctcagatgtcacaggtaaagcaggaagtgacgagaatgaagaggagccc
gggatgaaggctgtgtccacttcaccaggggggcgtttcctcaagtttgacattgagctg
ggcagagggtccttcaagaccgtctataaaggtcttgacaccgacacctgggttgaagtg
gcatggtgtgaacttcaggagcggaaactgtccaaagctgagagacagaggttcaaagag
gaggcagagatgttaaaggctcttcagcatcccaacatcgtgcggttttatgacttctgg
gaatcaccggttaaagggaagaagtgcattgttctggtgacggagctgatgacctcaggg
acactaaaaacgtatctgaagcggtttaaggtgatgaagccgaaagttttgaggagctgg
tgcaggcagattctcaaaggcctccactttctccacacaaggactcctccaatcatccac
agagatctcaagtgtgacaacatcttcatcactgggcccacaggctcggtcaagatcgga
gacctgggcctggcaacactgaagagggcctcctttgctaaaagtgttattggcactcca
gagttcatggccccagagatgtacgaggagcactatgacgaggctgtggatgtctatgcg
tttgggatgtgcatgctggagatggccacctcagaatatccctactctgagtgtcaaaac
gcggctcagatctaccgcaaagtcaccagtggggtgaaacctgccagctacagcaaagtc
agtgacccagaaattaaggaaataattggtgaatgtatctgccacagaagggaggaaagg
tactccatcaaggacctcctgaaccatgccttctttgcagaggacacaggcgtgagggtg
gagctgaatgaagacgatgatgggaagaaatcatccattgctctgaagctgtgggttgag
gatactaaaaagctgaaggggaaatacaaggacactggtgccattgagttttccttcgac
ttggtgaacgaggtcccagaggttgttgcccaagaaatggtggaatcgggttttttcctg
gactgtgatgtgaagatagtcgggaagtccatccgggaccgcgtggctctcatcaagtgg
cggagggagcggactttctcgtcagcaaatggcgatgtagctgtgaagaagccgcagcag
aacctactgcaagtgcccggtgctgttgtaccccaggcacccacattagttacgacagat
tatgaggagcaagaaggggagcagcagaccctgatctgcaccgtgccagtcaccatgact
gccacatctgacagcggagtgagctctaccatgcaattagatgacctaaacaatcagcaa
aatggcacctaccagtcgcttccagagcccatttcctcagctcatgtgatctacagtcct
cctgaccctcagctgcaccaggggccctaccagcaacccacagcacaggcctctcatgaa
aactacacacaagcatccactccattacaccagggagcctaccagcaacccgcaggtcag
ctgcatcctggggcctatcatcagcccgcagcacaactgcaccaggggccttatcagtct
caaacaacagtttctgctccagctacaccagcccctattgtgcaccagagtagacagaca
gcacagagcttcccagctgcagcccccactctacagccacagcttactgcccagtccagc
caggagcagtgccctctccaaccagctgctgtcctgccccagctgttatctgctgaccag
cctacaactcacctgagtcctcctgacatatccaccagttttccacagtcagtgtccagt
gctcctcctccactcctgcccctgcagatcagcacacagtttccctcaccatatcctgtt
actcaaacagggggcctcatgccctctccctttcccccagctcctctgccatgtgcctac
agcagcagtggcccttctacatctagctcccatttctcaccttcaccccatcatccctcc
cttcctctgacccctcatgctgccttgccctctgtaccctctctcagcacccctcagaca
cctctatccacacctcagcacgtgcccagtgtggcgctccctattccacttcttgccatg
tcctctgcagtgtcccagcagaagggcagccctttcacatctcagactaacctcggtagc
ttccataccacccatcccttacctttctcccaggtacaacccaccccataccccgccccc
taccctgagcaagaattgtctcagccgcctttccaggtacagatgattgcaccacaaggt
aatctgggagattttccccttttggctccggcccacccagtcttgcctactcctctctgg
gggagcggagtcgatgcagaaacttctgcagctagccgagacttaactgtagctccaaca
gtcccagcttcggtcccagccccagtatcagacccagcctcaatctctgctacagcccaa
gctgaaactcaagcctcagcacaaactccagcttcgacctctgttagcgccccaacttca
gccccaatacaagttccaacagcagcgcaagccatatcctcagtcccagttcaagcaccg
gtctctgcatcgggtcttgcttttgaatcaccaaaaggctcatcgactagctcagataca
tcctctgcaactggtaaacccaaactctcagtcccaggcttaggctctgccccaatccct
gtcacgttgccagccccagctcctgtcgcagcttcagtcccagctccagttctgcagcct
gctggcatccagacagcagtctcagtgtctgagtgtgccagcctggctacaactcagcaa
aaccttgagtcgacatctgcatccagcacccttcaacaagagccctgtggagaggatgtg
cttcaagacaaacctgtatctttacgcagttacacctatgacagtctcaactctgatgtg
gcatctggtaaggaaacaagtgacggctatgacagcttggctagtggaggcaagggggac
ggaaaacccaggaaacaccaccgcaagtctgctcgcacacgctcccgacaagaaaagacc
agcaaacccaaactgagcatgctcaatgtttgcaacactggtgataaaatggtcgaatgc
cagctggagactcacaaccacaaaatggtgacatttaaatttgatctggatggagatgct
ccggaggagattgccacttacatggtagagaatgggtttatccttctgctagagaaggag
atcttcatcgatcagctgaaggacatagtggacaaagctgaagacatgctgaacgaagac
atggagggtgaacgggccactgccttgagttgcagtcctgaacaaggccagatttccgaa
ggactggttggagagagtcagcagcctggagcatctcagcctgtctatcagcagaatgtt
cttcacacaggaaagagatggttcataatctgccctgtagaggagacgcccacatccagt
caggagacgccatctgatggcacagcaacacagtctcctgggagctcagccactactcag
cctgctgacactgggactgcaaggccgtctacatccagagaagaggggtcatcctccaca
atgtctggtggaagtggaggcttcacctatgatgtgtatggattctgtagccccccaata
atgtccaacacagaccctctactcttagctactctgtctccacctgtgtctgctccccca
acccttcagtcagtgacatcagtggagcctgcggggggctcggtgcagcccagtgttcat
caggcccagccagccagagctcaaactttgcccccatcatccccgcatacatctttccca
gtggatgagtcacggggatccccgttgggctccatctccccgattgattcagctcaacag
atgccagacgtgacatgcccggtgtctgtggctgacgaggtgccctgctgccctctggtc
atgcccttgtctctggatgtgagcggcttacagagtgggtctcctcttactcctcttcct
ctccaggaaccaggctcagccaaagaacctttgtctgtctcctacacctcgtcagcacgt
agcgagcacccacagcagcctgtggtgctgcaccagcctttttccagtgtgggcgggacc
aaagtgtcctcactaccccagagcccagcgccgtcccagcatggcgcagggcccggtgag
tcagacactgagggacggctgggccgcgggggctttgtggacagcaccataaaaacactg
gatgagaaactgaggaacttgctctaccaggaatatgctcccatgtatccatcaggcagt
gctgcagagacaccaggctccggcacagagtacatccagtctcctcctggtccagacagc
gccacaggagggtcaggaaacagcactccagggcccatgggggagggacgctacagggca
ggggaacagctgcctcaaattccagagagaatggacagtttgagcacactgagtgactca
gctgtgtgtgcatccctgtcaagaaggcacgttcctaactctgcttcctgctctggaaca
agaggcagatttaagataatctctgtccctcctgaagtggccaacagacgagatgtgaag
cagaggagctggagcagcgctgcctcacctgcgcaccctacaggatacagtgaggaccac
gtccaggctgagaccatgactgcctccaccacaattggtcgtttctctgtggttagcacc
gaagatgacattacacagaggacacgttgcagtcgctactccgccccgcctgatttctac
ctggacacacctccgtccatggccaagcgaggctctctgcctcgtgccaatacatcaaac
tctgtctctgtggatgtcactgtccacgctcgtttcctctcctcagactcgggtgctgag
agcagtcctgcgaagctgactcctgccaccccgtctcaacatactcgctctgagcgcaga
ggaagtgacctcatgaagagggcagtggccttcctccgtcgttcagggcgcagcagcagc
gtgcagagctctgactcaccaagcaggcatggaggcgtgcatggctcggcctatgccagc
agtgataatgactcagagatggaggactcggacatgaagaaggagctacagagactgagg
gagaaacatttgagggagatctctgagctgcaggcccatcagcggggggaggtggagctg
ctgtatcgccggcttggcaaagcccctccttctggcctgggtctctcacatgttgcacca
catgccggccgtaggaagaggtccggcaagcacagactgaagcctggcaaactcctcagc
cctctggttcaacagtttagaaatgtcacaactaaaacttgtgattccagcaaatccagt
actgctgcaggtacaggtgagcccacagtgagtttaaacggctctccagccaaaaggcct
ttccccactcacggcagggcacgctcatgcaccagccaccttcccagctcaaccacagag
cccgtgcagactcagcagccctgctccctcaagggctctttgtcttctgataatatttat
gctggattacatggagacggcaccagcacacacgctccacctggacaaggctggtctaat
taccctcaaacgtctgagagagtgacctataaatcgagtagcaagcctcgagctagattt
ctcagtgggcctgtgtctttgtctatctggacaacactgaagcgcctgtgtcttggcaaa
gagcgtggcagcaggtctggagctgggccaggggctttcaatcaaccacagcagcagcct
cccggtgccacacctccttctcatcagcctgtgatgggactggcccaagctcaggccaat
aacagcaacaacaagacaggcacatacactggctcatccatgagtgccaatgaaaacaac
ctgcctgaggacttgcagcggctcatggaggactgggcccaggaggttcttatcgtcagc
cacaggccgcgcaccaactctctgagcatcagcgggcagcagctttggaatcaggttgtg
cctcaaacacgtggacggctggatagtgcttcagatgtatcatggacagttccaggtcca
gaggcctgcaatcgtcccctgtcatggcctgatagccccgggtcaacagtgatgaccagc
ccctccatggggccccggcccagttatcagctccactcttctgctccattcagggccttg
ccctctcctctctctgtcagccagtggcctgggttgctctccccccttccttcaggagtc
tttgcctttcctgctgtgccctcagcccaggacgcccccagccccattctagccccatca
tatcagccgtccgaccccaaagccaggactctctaa

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