Embiotoca jacksoni (black perch): 138199813 Help Entry 138199813         CDS       T10523                                  Name (RefSeq) ryanodine receptor 3-like   KO K04963   ryanodine receptor 3 Organism eja  Embiotoca jacksoni (black perch) Pathway eja04020   Calcium signaling pathway eja04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:eja00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     138199813    04020 Calcium signaling pathway     138199813  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:eja04040]     138199813 Ion channels [BR:eja04040]  Voltage-gated cation channels   Ryanodine receptor    138199813 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  138199813 NCBI-ProteinID:  XP_069008131 LinkDB All DBs Position Unknown AA seq 4890 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCVACIQKENRKFCLAAEGLGNRLCYLEPTSEAKYVPP DLCICTFVLEQSLSVRALQEMLAKSGQNSEGRLIRKAAHSGGHKTLLYGHAILLRHSFSS MYLACLKTSRSQTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVS SERYLHLSISNGNIQVDASFMQTLWNVHPICSGSNIEEGYLLGGHVMRFFHGHDEVVTIP GSDQSEEQQRIVNYETGKAGAKARSLWRLEPLRISWSGSHIRWGQPLRLRHLTTGHYLAL TDDRGLVLQDRERSDTVATAFCFRASKEKLEQSPKRDIEGMGVAEIKYGDSLCFIMHVAT GLWLSYQAPDVKSSRLGPLKRRACLHSEGHMDDGLTLQRCQHEESCAARIIRNTTLLFNR FIRDLDCLGVKNRALVALPVEEVLQTLNDLITYFQLPDAELEHEERQIKLRSLKNRQNLF KQEGMLTLVSNCIDRLNVYNSAAHFGECAGPEAGAAWKDILNLLYELLAALIRGNRNNCT QFSNNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKSIISLLYKHGRNHK ILDVLCSLCVCNGVAVRTNQNLICDHLLPKRDLLLQTQLVNDVQSMRPNIFLGVSEGSAQ YKKWYYELMIDQVDHFVTSEPSHLRVGWANTKGYAPYPGGGEGWGGNGVGDDLYSYGFDG LHLWSGRIPRAVASMNQHILTSEDVVSCCLDLGAPSISFRINGQPVQGMFENFNTDGLFF PVVSFSAGVKVRFLLGGRHGDFKFLPPSSYAPCYEALLPKEKMKVEPVKEYKRDVEGVRD LLGTTQFMSQASFIPTPVETSQIVMPPHLEKVRDKLAENIHELWGMNKIELGWSYGKIRD DNKRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCRVVQVNPNAEESLKKIKLPKN YMMSNGYKPSPLDLSDIKLTPGQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKSKRN PRLVPYVLLDERTKKSNRDSLREAIRTLIGYGYNIEPSDQESGQVVERLSIDKIRFFRVE RTYAVTTGKWYFEFEAVTGGDMRVGWARPGCKPDLELGTDELAFVFDGYRGHCLNMGSRL FGRCWHAGDVVGCMINMEDKSMIFTLNGEILITTKGSELCFTDFETEDGFIPVCSMGLSQ VGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPKDHNHIAVT RIDGTIDSPPCLKVTHKTFGTQNSNADMVFCRLSMPVEFHSFFKLSPVVDMNGVHEEDIL KVKHRYPLRSVRHSDESRRVDYSSITTYYHSVRVFAGQDPACVWVGWVTPDYHYYSNNFN LSKNRAVTVTLGDERGRVHESVRRSNCYMVWGGDVTSAAHTSSRSNVDLEIGCMIDLATG LVTFTVNGKETSTSYQVEPNTKLFPAVFVRPTSPNLFQLELAKIKNAMPLSSAIFKSEHK NPVPQCPPRLDVQTINAVLWSRMPNTFLKVETARVNERHGWVVQCVEPLQMLAVHIPEEN RCVDIMELSEQEDMRTFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSG MLREGFYNVLISIHLETAKEARLMMKDEFIIPVTAETRSIRLFSDASKKHLPPGVGLSTS LKPRLNFAPPCFISIKREHLFSPQIPLDSLKEKSILMLTEAVQGGGHHIRDPVGGGVEYQ FVPILKLISTLLTMGVLVSEDVHKILLLIDPNVFREAHEEGATGATDKEGLTGSEDKAVE AGEEEAAKEAKQPMKGLLEKRLPEPVKRQMCELLHYFCDCELKHRIEAIVSFSDNFVSKL QYNQKFRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLTFSMGEDCPCPTDIQEELY DFHNQLQLHCGIPMEEDEDEQDSSIKGRLLILVNKIKGQSHKAEEPTEKEQAAPSNLKEL ISQTMVSWAQECHIQDSELVRKMFSLLRRQYDSIGELLRAMRKTYTISGVSVQDTINLLA ALGQIRSLLSVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRILGMHETVMEVMVNVLGG DKSQEIAFPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLD VAASSVMDNNGLALALEEPDLDKVVTYLAGCGLQSCPMLLAKGYPDIGWNPIEGERYLSF LRFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMKEAIKISETPALDL PGSVQGVGSDVFSTVRSADGDDEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGE ALRIRAILRSLVPTEDLVGIISILLKMPIVNKDGSVTEPDMSASFCPDHKAPMVLFLDRV YGIEDQSFLLHLLEVGFLPDLRAAASLDTEGLCTTETALAMNRYIGSAMLPLLTRCAPLF AGTEHYATLIDSTLHTIYRLSKGRSLTKAQRDAIEECLLSVCKHLRPSMLQQLLHRLVFD VPLLTDYCKMPLRLLTNHYEQNWKYYCLPSGWGSFGTASEDELLLTKKIFWGVFDSLSQR KYDPELFKMAMPCLSAIAGALPPDYVDASITTTVEKPVSVDAQGNFDPKPINTANIALPE KLEHFANKYAEHSHEKWSAEKVLLGWKYGDCVDEKMKIHPQLRTYKGLTEKEKEIYRWPI RESVKSMLAMGWSIDRTKDGESMSQQRESEKMRKISQSSQANGFNPSPIDTSNVVISREL QGMVEVVAENHHNIWAKKKKSDLGSRGGGTHPLLVPYDTLTAKEKARDREKAQDLFRFLL INGYSITRGLKDLEHDSSSMEKRFAYKFLKKLLKYVDSAQEFISHLEAMAASGKTDRSPH EQEIKFFAKVLLPLIDQYFKNHSLYFLSSPNKNLSSSGYASNKEKEMVTSLFCKLAALVR HRISLFGSDSTTMVSCLHILAHTLDTRTVMKSGSELVRVGLRTFFENAAEDLEKTFENLK LGKFSHSRSQMKGVSQNINYTTVALLPILTALFEHITQHHFGVDLLLDDVQVSCYRILTS LYALGTGKNIYVERQLPALGQCLATLAGAMPVAFLEPLLNSYNPCSVFNTKSARERAILR IPDSVEEMCPGMPRLDGLVKDINDMAESGARYTEMPHVIEVVLPMLCNYLSYWWERGPEN QPASGGSICCTTVTSEHLSLILGNILKILNNNLGIDEASWMKRIAVYVQPIISKARADLL KSHFLPTLEKLKKKTVKVVAEEELLKADSKGDTQEAELLILDEFAVLCRDLYAFYPMLIR YVDNNRSRWLKEPDSDSNELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDN KTKMSKSGGQDQERKHKKRRGEFYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTR YLLKDTDDEVKDHIHQNLHLREKSEDPAVRWQLNLYKDIVMRTDWPPDPERVVDRIQRIS AAVFNLEQVEQPLRSKKCVWQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLLAYQRI WIETEEYSFEEKLVQDLAKTQPKEEEEEEEEIRKQPDPLHQLILHFSHNALTECSSLEED PLYIAYADMMAKSCDEGEEEEEEEGKEKTFEEKEMEKQKMLYQQARLHDRGAAEMVLQMI SASKGRLDAIVTFTLKLGISVLNGGNILVQQKMLDYLKEKRDVGFFKSLSGLMMSCSVLD LNAFERQNKAEGLGMVTEEGSINVSERGSKVLQNDEFTTDLFRFLQLLCEGHNNDFQNFL RTQTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVIDEAGQRNFSKALAVAKQVFN SLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDM IVMMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDSFKEYDPE SKGVISKKDFQKSMENQKQYSQSEIEFLLSCAEADENDMFNYEQFVERFHEPAKDIGFNV AVLLTNLSEHMPHDGRLATFLDLAESVLSYFEPYLGRIEIMGGAKRIERVYFEISESSRT QWEKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASLISEPDPVERPEED EDDKQNVVEKQEEEEDENIMMESSSAFTIACISMRKSLCHFRQLLTLKSMRRQYRKFRKM SVREMVRGFFSFFWMIITGLFHFVYSLVWGFFHILWTTMFGGGLVEGAKNMKVTDILGNM PDPTQFGIHGDVLETEKMEANDASVLAEMAQMAQGEAAEADLMAELLNIQPKREGKHGAE PGLGDVSEVVVGDAPSIASAVKQKKAQMAAKKSVTNGDYKSDSEKGDSEDGEKKDHDKSK DETPPERSVEGKKVPKKRLGPKKEPPEVFMASFFAGLEVYQTKMLNYLARNFYNLRFLAL FVAFAINFILLFYKVTGDYSDDEDPWNGQGRAGEEEDDGALEYFVLQESTGYMAPTLRCL AILHTIISFLCVVGYYYLKVPLVVFKREKEIARKLEFAGLYITEQPSDDDIKGQWDRLVI NTPSFPNNYWDKFVKRKVIKKYGDLYGAERIAELLGLDKSALDFNPTEETVAKEASLVSW LSSIDAKYHIWKMGVVFTDNSFLYLVWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTIL SSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHM YVGVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQ EQVKEDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQE SYVWKMYQERLWDFFPAGDCFRKQYEDQLG NT seq 14673 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagaaggagaggatgaaattcagttcctccgaactgatgatgaagtg gtgcttcagtgcgtggcctgcatccagaaggagaatcgcaagttctgcctggctgctgag gggctgggcaaccggctgtgttacctggagcccacatccgaggcgaagtatgttcctcca gacctctgcatctgtacctttgtactggaacagtctctgtctgtgcgggccctgcaggag atgctggctaagagcggacagaacagcgaagggaggctcataaggaaggcagcgcacagc ggcggacacaagaccctactgtatggacacgccatcctcctgcggcattccttcagctct atgtacctggcctgtttgaagacatcaaggtcacagacagataaactgtcctttgatgtc ggcctgcaggaggattcaacaggtgaggcgtgctggtggacgatccaccctgcctccaaa cagagatctgaaggagagaaagtgcgcatcggtgatgacctcatcctcgtcagcgtgtcc tcagagcgataccttcacttatccatctccaatggcaacatccaagtggatgcgtccttc atgcagactctgtggaacgtccatcccatctgctccgggagcaacatagaagaaggctac ttgttgggtggtcacgtgatgcggttcttccatggacatgacgaggtggtgaccatccca ggatcagaccagagtgaagagcagcagaggatagtcaactatgagacgggtaaagccggt gccaaggcgaggtccttgtggaggctggagcctctccgaatcagctggagcgggagccac atccgctggggtcagcccctccgactacggcacctaaccaccggtcactacctggccctg actgatgacagggggctggtgctgcaggaccgggagaggtccgacaccgtcgccacagcc ttctgctttagagcctccaaggagaagctggagcagagccccaagcgggacattgagggc atgggggtggcggagattaaatacggggactcgctctgcttcatcatgcacgtggccaca ggtctctggctctcctaccaggcacctgatgtcaaatcgtctcgtctgggtcccctcaag agaagagcatgcctacactctgaaggtcacatggatgacggcttgaccctccagcgctgt caacatgaagagtcctgcgctgcgcggatcatccgcaacaccacgctgctctttaatcga ttcatcagagacctggactgtctgggtgttaaaaatagggcactggttgcgctgcctgtc gaggaggtgctccaaaccctcaacgacctcatcacctatttccagctccctgatgctgag ctggagcacgaggagaggcagatcaagctgcgctcactcaagaacaggcagaaccttttc aaacaagaaggcatgctgactctggtgtccaactgcatcgaccgtctgaacgtctacaac agcgcggcccacttcggggagtgtgccgggcctgaggccggagccgcctggaaggacatc ctcaacctgctgtacgagctgctggcggcattaatccgagggaaccggaacaactgcacc cagttctccaacaacttggactggctggtgagcaagctggagagactggagtcttcctca ggcatcctggaagttctgcactgcattctaattgagagcccagaggcgctcaacatcatc cagagaggacacattaagtccatcatatcgctgctctacaagcatggacgcaaccacaag attctggacgtgctgtgctctctgtgtgtgtgtaacggtgtggctgtgcgaaccaatcag aacctcatctgcgatcacctgctgcccaagagagatctgctgctgcaaacccagctggtc aacgatgtccagagcatgagaccgaacatcttcctgggggtgagcgagggctccgctcag tataagaagtggtactacgagctgatgatcgaccaggtggaccacttcgtgaccagcgag ccctcccacctgagagtgggctgggccaacactaaaggatacgccccctaccctggagga ggagagggctgggggggcaacggagtcggggatgacctctactcgtatggttttgatgga ctccacctctggtcaggtcgtatcccacgggcggttgcgtccatgaaccagcacatcttg acctcggaggatgtggtgagctgctgtctggacctcggagcgccgagcatctcgttcagg atcaacggacagcccgtccaaggcatgtttgaaaatttcaacacagacgggctcttcttc cccgtcgtcagcttctccgcgggggtcaaggtacgcttcctgttgggtggccgacacggc gactttaagttccttcctccatcaagttacgctccgtgttacgaggctctgctacccaaa gagaaaatgaaggtggagccagtgaaagagtacaagagagatgtggaaggagtccgagat ctgctgggcaccacccagttcatgtctcaggcctccttcatccccacacctgtggaaacc agccagattgtcatgccacctcatttggagaaggttcgggacaagctggctgagaacatc catgaactgtggggcatgaataagattgagctgggatggtcatacggcaagataagggat gataataagcggcagcatccgtgcctggtggatttctccaagctgccagagacggaaaag aactacaatttgcagatgtcaacagaaactctcaagaccctgctggcgttgggttgccgt gtagttcaagtgaatccgaacgctgaggaatccctcaaaaagataaaactcccgaagaac tacatgatgtccaatggttataagccatcccctctggacctgtctgacatcaaactgact ccaggtcaggaactgttggtggacaaactagcggagaatgcacacaatgtgtgggccaag gaccgcatcaaacagggatggacgtacggcattcagcaggatctgaagagtaagcgtaac ccccgcctggttccttatgttctgctggatgagaggaccaagaagtcgaacagggacagc ctgcgggaggctattcgcactctgattggctacggatacaacatcgagccctcagaccag gaaagcggacaagtggttgagcggctcagcatcgataagatccgcttcttcagggtagag aggacgtacgcagtgacgaccgggaaatggtactttgaattcgaggccgtcacgggagga gacatgcgagtgggctgggccagacctggatgcaagcccgatctggagctcggcacagat gagctcgctttcgtctttgatggatacaggggccactgtctgaacatgggcagccggttg ttcgggcgctgctggcacgccggggatgtggtgggctgtatgatcaacatggaggacaag tccatgatcttcactctgaacggggagattctcatcaccaccaagggctctgaactctgc ttcaccgactttgaaactgaggatgggtttattccagtgtgtagtatgggcctttctcag gtgggacgtatgaacctggggaaggatgctagcaccttcaagtactacaccatgtgcggc ctgcaggaaggatttgaaccctttgctgtcaacatgaaccgtgaggtcacgatgtggttc agcaagcgtctgccgactttcgtcaacgtaccgaaggaccacaaccacatcgcagtaacc aggattgacggcaccatcgacagccccccgtgtcttaaagtcacccacaagacgtttggc acccagaacagtaatgctgacatggtgttttgtcgtctcagcatgccggtcgagttccac tccttcttcaagctcagtcctgtcgtcgacatgaacggagtgcacgaggaagatatcctg aaagttaaacacagatatcctttgagatctgtgaggcacagtgatgaaagcagacgcgtt gactacagcagcatcactacgtactaccactcagtgagggtcttcgcaggtcaggacccc gcctgtgtgtgggtcggatgggttacccccgactaccattactatagcaacaacttcaac ctcagcaaaaaccgagcagtgactgtaaccctcggggatgaacgaggacgagtccacgag agcgtgaggagaagtaactgctacatggtgtggggcggtgatgtgaccagcgctgcccac acctccagtcgcagcaacgtggacctggagatcggctgcatgatcgacctggccaccggc ctggtgacattcaccgtcaacggcaaggagacatccacgtcctaccaggtggaaccaaac accaaactcttcccggctgtgtttgtgcgacccaccagcccgaacctcttccagcttgaa ctggctaaaataaagaatgccatgcctctgtcgtcagccatctttaagagtgaacacaag aacccggtgccccagtgtcccccccgactggatgtgcagaccattaacgcggtgctgtgg agccgcatgcccaacaccttcctcaaagtggaaacggctcgggtgaacgagaggcacggc tgggtggtccagtgtgtggagcccctgcagatgttggcggtgcacatacccgaggagaac cggtgcgtcgacattatggagctgtcggagcaggaggacatgaggacgtttcactaccac accttgaagctgtactgtgccctctgcgctctgggaaacacccgtgtggctcacgccctc tgcagtcacttggaccagtcgcagctcttatacaccatcgacaatcagtacctgtccggc atgctgcgtgagggcttctacaacgttctgatcagcatccacctggagacggccaaggag gcccgactcatgatgaaagatgagttcatcattcccgtcacggcggagacgcgctccatc cgtcttttttctgatgcctctaaaaagcacctcccgccgggggtggggcttagcacttct ctcaaaccccgcctcaactttgctccgccctgtttcatcagcatcaaacgggagcacctg tttagtccccaaatcccactggattcgctgaaggagaagtcaatattaatgttgacggag gctgttcaaggtggagggcaccacatccgagatcctgtgggaggaggtgtggagtaccag tttgtgcccatcttgaagctcatcagcaccttgctcacgatgggtgtgttagtgagtgag gacgttcataagattctcctgctcattgacccgaacgttttcagagaggcgcatgaggag ggagcgacgggggccacggacaaagaaggactgacggggagcgaggacaaggcagtggaa gctggagaagaggaggcagccaaagaggccaaacagccaatgaaaggactgctggagaag aggctgccggagcccgtcaaacgacagatgtgcgagctgcttcactatttctgcgactgc gagctgaagcaccgcatcgaggccatcgtgtccttttccgacaacttcgtctccaagctg cagtacaaccagaagttccgctacaacgagctgatgctcgccctcaatatgtccgccgcc gttacggcaaagaagaccaaagagttcagatcgcctcctcaagagcagatcaacatgctg ctgaccttcagtatgggcgaagactgtccgtgtcctacagacatccaggaggaactctat gatttccacaaccagctgcagctccactgtggaatccctatggaggaagacgaagacgag caagattcgtctattaaaggtcgcctcctaatactagtgaacaagatcaaaggccagtcg cacaaagcagaggagcccacggagaaggagcaggcggcaccatccaatctgaaggagctc atctcccagacgatggtcagctgggctcaggagtgtcacatccaggattcggagctcgtc cgcaagatgttcagcctgctgaggaggcagtacgacagcatcggggagctgctccgggcc atgaggaagacgtacaccatcagtggcgtctcggtccaggacaccatcaacctcctggcc gccctcggtcagatcagatctctgctgtctgttcgtatgggaaaggaggaggagaagctc atgattgatgggttgggtgacatcatgaacaacaaggttttctaccagcatccgaacttg atgagaattctgggcatgcacgagacggtcatggaggtcatggtcaatgtgctcggagga gacaagtcccaggaaattgccttccccaagatggtggccagctgttgtcgcttcctgtgt tacttctgtcggatcagccgtcagaaccagaaagccatgtttgaccacctcagctacctg ttggagaacagcagtgtgggcctcgcttcaccagcgatgagaggctccacgcctctagat gtggctgcttcctctgtaatggacaacaacggcctggctctggcgctggaagaaccggat ctggacaaggtggtcacctacctggctggctgcggtcttcagagctgtccgatgctgctg gcgaaaggttatccagacatcggctggaaccccatcgagggagagcgttacctctccttc ctgcgctttgctgtctttgtcaacggagagagtgtggaggagaactccagcgttgtggtc aaacttctcatccgtcgtccggagtgtttcggacctgccctgagaggagagggcgggaac gggctgctggctgccatgaaggaagccattaagatctccgagacgccggctctggacctg ccgggctccgtccagggagtcggctcggacgtgttttccaccgtgaggtctgctgacggg gatgatgaggaggaggtggtccacatgggcaacgccatcatgtcattctactctgcgctc attgacctgctgggacgttgtgcccctgagatgcatctcatcaacaaggggaaaggagaa gctctgcgtattcgtgccatcctgcgctctctggtgccaactgaggatctcgtgggaatc atcagcatactgctcaaaatgcccatcgtcaacaaagatgggtcggtgacagagccggac atgtccgccagcttttgtccggaccacaaggcgcccatggtgctgtttttagacagggtg tatggtatcgaagaccaaagctttctgcttcacctgctcgaagtgggcttcctccccgac ctgagggctgctgcctctctggacacggagggtctgtgcaccacagagacggccctggct atgaaccgctacatcggctcagccatgctgcccctcctcacccgctgcgctcctctcttc gccggcaccgagcactacgccaccctcatcgactccaccctgcacaccatctaccgcctc tccaagggacgctcgctgaccaaggcgcagagagacgccatcgaagagtgcttgctgtct gtttgcaagcacctccgtccctccatgctgcagcagctcctacaccgcctcgtctttgat gtgcccttgctcactgattactgcaagatgcctctaaggctgctaaccaaccactatgag cagaactggaagtactactgcctcccatcgggctggggcagcttcggcacggcatccgag gacgaactgctactcaccaagaagattttctggggagtgttcgactctctttctcagagg aagtatgacccagagctgttcaagatggccatgccttgcctcagtgccatagctggagct ttgccaccagactatgttgatgcctcgattactaccactgtggaaaaacctgtttctgtg gatgctcagggcaactttgaccccaaaccgatcaatactgctaacattgctcttccagag aagcttgagcattttgccaacaaatatgccgagcactcccatgagaaatggtctgcagag aaggtgttgctggggtggaaatacggagactgtgtggatgagaagatgaagattcaccct cagctcaggacctacaaaggcctgacagagaaggaaaaggagatttacagatggccaatt agagagtccgtgaagagcatgctggcaatgggttggagcatcgacaggaccaaggatgga gagagcatgtctcaacagagggagagtgagaaaatgagaaagatctctcagtcttcgcag gccaatggtttcaacccaagcccgatagacaccagcaatgtagttatatccagagaactg caggggatggtggaggtggtggctgaaaatcaccataacatctgggccaagaagaaaaaa agcgaccttggaagcagaggtgggggaacgcaccctctgctggtgccctacgacacgctg acggccaaggagaaggcccgcgaccgagagaaggctcaggacctttttcgcttcctgctt atcaatggctacagcatcacaagaggtctgaaggatttagagcacgattcctcctccatg gagaaaaggtttgcctataaattcctcaagaagctgctcaagtatgtcgactcagcccag gaattcatttcccacttggaggccatggccgccagcggaaaaacagacaggtcacctcat gaacaggaaatcaagttttttgccaaagtacttctccctctcatcgaccaatacttcaag aaccactccctgtacttcctctcctcccccaataagaacctgagcagcagtggttacgcc tccaacaaggagaaggagatggtcaccagcctgttttgtaaactggcagctcttgtcaga cataggatttcactatttgggagtgactccaccaccatggtcagctgtctgcatatcctg gcacacactctggacaccaggacggtgatgaagtcgggctcggagctggtgagggtgggg ctgaggacgttctttgagaacgctgcagaggacctggagaaaaccttcgagaacctgaag ctggggaagttcagtcactcccgctcgcagatgaaaggagtgtcacagaacatcaactac accaccgtggctctgctccccatcctaacggctctgtttgaacacattactcaacaccac tttggagtcgacctgcttttggatgatgtccaagtgtcctgctatcgaatcctgactagc ctctatgcactgggcactgggaaaaacatctacgtagaaagacagctgccagctctcggt cagtgtctggccactctggccggggcgatgcctgtagccttcctggagccgctgctcaac tcgtacaacccctgctccgtctttaataccaagagtgccagagaacgggccatcctgaga ataccagactcggtggaggagatgtgtccggggatgccgcggctggacggcctggtgaag gacatcaatgacatggctgagtctggagcccggtacacagagatgccccatgtgatcgag gtggtgctgcccatgctgtgtaactatctgtcctactggtgggagaggggtcctgaaaac cagccagcgagcggggggagcatctgctgcaccaccgtcacctcagagcacctcagcctc attcttggcaacatccttaagatcctcaacaacaacctgggcatcgacgaggcctcctgg atgaagagaattgcagtttatgtacagcccatcatcagcaaggcccgtgcagatctgctg aagagccacttcctgcccacgctggagaaactaaagaagaagacggtgaaggtggtggct gaggaggagcttctcaaggcggacagtaaaggagacacccaggaggccgagctgctcatt ctggacgagttcgccgtcctctgcagggacctgtacgccttttaccccatgctcatccgc tacgtagacaacaacaggtccaggtggttgaaagaacccgattcggactctaatgagctc ttcagaatggtcgctgagatatttatcctgtggtgcaagtcacataatttcaaaagagaa gagcagaactttgtggttcagaatgaaatcaacaacctctccttcttgactggagataat aaaacaaagatgtcgaagtcgggaggacaagaccaggagcggaaacacaagaagaggcgc ggggagttctactccatccagacctcgctgatcgtcgctgctctgaagaagatgctgccg atcggtctcaacatgtgcaccccgggcgatcaggagcttatctcactcgccaagacccgc tacctcctgaaagatacggatgacgaggttaaagaccacattcatcaaaatctgcacctc agagaaaaatcggaggaccccgccgtgaggtggcagctgaacctgtacaaggacatcgtg atgaggactgactggcctccggatcctgaacgagtggtagatcgtatccagaggatctcg gctgcagtcttcaacctggagcaggtggagcagccactgagatccaaaaaatgtgtttgg cagaagttgctgtccaagcagaggaagcgagcagttgttgcctgcttccgaatggctccg ctctataacctgccaaggcatcgctctattaacctcttcctcctggcctatcagagaata tggatagaaacagaggagtactcttttgaggagaagctagtgcaggaccttgcaaaaaca cagcccaaagaggaggaagaggaagaggaggagatcagaaagcagccagacccccttcat cagcttattctgcatttcagccacaacgctctgactgaatgcagttctctggaagaggat cctttgtatattgcctacgcggatatgatggcaaagagttgtgatgaaggtgaagaagag gaagaggaggaaggaaaagagaaaacatttgaggaaaaggaaatggaaaaacaaaagatg ctgtatcagcaggccagactgcatgaccgtggagctgcagagatggtgctgcagatgatc agtgccagcaaaggtcgacttgatgctatcgtgactttcaccctcaaactgggcatctcc gttctcaacgggggaaacatactggtgcagcagaaaatgctggactatctgaaggaaaaa agagacgttggcttttttaaaagtttgtctggactgatgatgtcatgcagtgtcctggac ttgaatgcttttgagaggcaaaacaaagccgaaggtctggggatggttaccgaagaggga tcaatcaacgtgagtgagcggggttccaaggtgctgcaaaacgatgagttcactacggat ctctttaggtttctgcagcttctctgtgagggccacaacaatgattttcagaacttcctg aggacccaaacaggaaacacaaccacagtcaacatcatcattagcactgtagactatctg ctaagactccaggaatccatcagtgatttctactggtactactccggtaaggatgtgatt gatgaggccggtcagaggaacttctccaaagcgctggcagtggccaaacaggtgttcaac tctttaacagagtatatacagggtccatgtatcgggaaccagcagagtctggctcacagc aggctgtgggatgcagtggtgggattcttgcatgtgtttgccaacatgcagatgaagttg tcccaggactccagtcagattgaattactgaaggagctgctggacctgcagaaggacatg atcgtcatgatgctctctcttctcgaaggtaacgtagtcaacggaacgattggcaaacaa atggtggacactttggtggagtcttctagcaatgtggagatgatcctgaaattcttcgac atgttcctcaagttgaaagacttgaccacctccgacagcttcaaggagtacgaccccgag agcaaaggggtgatctcgaagaaggatttccagaagtcaatggagaaccagaagcagtat tctcagtcggagatcgagtttcttctctcctgcgccgaagccgatgagaacgacatgttc aactacgagcagtttgtggagagatttcacgaaccggcaaaagacatcggtttcaacgtg gccgtgttactgaccaacctatcggagcatatgccccacgacggtcgcctggcaaccttc ctcgacctggctgagagtgttctcagctacttcgagccctatttgggtcgtattgagatc atgggtggagcgaagcgcatcgagagagtctacttcgagatcagcgagtccagtcgtacg cagtgggaaaagcctcaggtgaaagagtcaaagcgtcagttcatcttcgacgtggtcaac gagggcggggagagcgagaagatggagctgttcgtcaacttctgcgaggacaccatcttt gagatgcagctggcctctctgatttcagagccggacccggtcgagcgcccggaggaagac gaagacgacaaacagaacgtggtggagaaacaagaggaggaagaggacgagaacataatg atggagtcttcctcggcgtttacgatcgcctgcatctcgatgagaaagagcctctgccac ttccgccagctgctcactctcaagagcatgaggcggcagtacaggaagttcaggaagatg agtgtgcgggagatggtgcgaggcttcttctctttcttctggatgatcatcaccggcctc ttccacttcgtctacagcctagtttggggtttcttccatatcctgtggaccaccatgttc ggtggcggcctcgtcgaaggggccaagaacatgaaggtgacggatattttgggaaacatg ccagaccccactcagtttgggatccacggggacgtgttggaaacggagaagatggaggcg aacgacgcgtcggtattggcggagatggctcagatggctcagggggaggcagcagaggcg gacttgatggctgagttgctcaacatacagcccaagagggagggcaagcacggggccgag ccaggcctgggggatgtgtcggaggtggtggtgggagatgctccatcgatcgccagcgcc gtcaagcagaagaaggcgcagatggctgcaaagaagagcgttacaaatggagactacaag tctgattcggagaaaggagattcggaagatggggagaagaaggaccacgacaagtccaaa gacgaaacccctccagagcgctcggtggaggggaagaaagtcccaaagaagaggctcggc ccgaagaaggaaccgccggaggtcttcatggccagcttcttcgctggcttggaagtctac cagactaagatgctgaactacctggccagaaatttctacaaccttcgtttcctggcactt tttgtcgcctttgccatcaacttcattcttctcttctacaaagtgactggtgattactca gatgacgaggacccgtggaacggtcaagggagggccggagaggaggaagacgacggagcg ctggagtacttcgtcctgcaggagagcacgggttacatggcaccaacgctgcgctgcctg gcgatactgcacaccatcatctccttcctgtgtgtagtgggatactattacctgaaggtg cctctggtggtgttcaaacgggagaaggagattgcgaggaagttggagtttgccggcctc tacatcaccgagcagccgtctgatgacgacatcaaaggacagtgggacagactggtcatc aacactccttcctttccaaacaactactgggataaatttgtcaagcgcaaagtgataaag aagtacggagatctgtacggagcagagaggatagcagagctgctggggttggacaagagt gccctggatttcaaccccacagaggaaactgttgccaaggaggcttcgctggtgtcatgg ttgagctcgatcgatgcaaagtaccacatctggaaaatgggggtggtgtttactgacaat tcattcctgtatctcgtttggtacaccaccatgtccatcctgggccactacaacaacttc ttcttcgctgcccatctgttggacatcgccatgggcttcaagaccctccgaaccatcctc tcttctgtcacgcataacggcaaacagctggtgttgacggtgggcctgctggcggtcgtg gtctatctctacactgtggtggccttcaacttctttaggaagttctacaacaagagtgag gacgaggatgagccggacatgaagtgtgatgacatgatgacgtgctacctgttccacatg tacgttggcgtgagagcaggagggggcatcggggatgagatcgaggacccagctggtgac ccctatgagctctaccgcatccttttcgacatcaccttcttcttcttcgtcatcgtcatc ctcctggccatcatccagggtttgatcatcgatgcctttggggagctgagggaccagcag gaacaagtcaaagaagacatggagaccaaatgtttcatttgtgggatcggcaacgattac tttgacacgacaccccacggctttgagactcacaccttacaagagcacaatctggccaac tacctatttttcctgatgtacctcatcaacaaggatgagaccgagcacaccggccaggag tcgtacgtgtggaagatgtatcaggagcgcctctgggatttcttcccagccggagattgc ttccgtaaacagtacgaagatcagctgggctag

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