Embiotoca jacksoni (black perch): 138205650 Help Entry 138205650         CDS       T10523                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism eja  Embiotoca jacksoni (black perch) Pathway eja04020   Calcium signaling pathway eja04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:eja00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     138205650 (ryr3)    04020 Calcium signaling pathway     138205650 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:eja04040]     138205650 (ryr3) Ion channels [BR:eja04040]  Voltage-gated cation channels   Ryanodine receptor    138205650 (ryr3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 Mis12 EF-hand_8 MliC Motif Other DBs NCBI-GeneID:  138205650 NCBI-ProteinID:  XP_069017865 LinkDB All DBs Position Unknown AA seq 4859 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSAASIQKEHRKFCLAAEGLGNRLCYLESTSEAKHVPP DLCICNFVLEQSLSVRALQEMLANTGQSSEGSADHEKWRLIKKAGQGGGHRTLLYGHAIL LRHSFSGMYLTCLKTSRSLTDKLSFDVGLQEDSIGEACWWTIHPASKQRSEGEKVRIGDD LILVSVSTERYLHLSISNGNIQVDASFMQTLWNVQPTCSSGNMAVGFLIGGHVMRLCHGH DESLTIPGADKSEEEQRIVNYEAGKGASRARSLWRLEPLRISWSGSHIRWGQAFRLRHLA TGHYLALTEDRGLVLQDREKSDTSATAFCFRASKEKGDSGPKKDIEGMAVPEIKYGDSVC FIMHLETGLWLSYQAPDAKSSRLGPLKRRACLHSEGHMDDGLTLQRCQHEESRAARIIRN STFLFTNFIKALDRTADGESTAVAGYVEEVLQTLNDLIEYFKQPDLELEHEEKQCLLRSL IKRQDLFKEEGMLSLLSKCIDRMNVYNSAAHFGEMAGEEAGAAWKDILNLLYELLASLIR GNRNNCTQFSRNLDWLVSKLERLESSSGILEVLHCILVESPEALNIIQKGHIKSIISLLY KHGRNHKILDVLCSLCVCNGVAVRTNQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLG MAEGSAQYKKWYFELVIDQVDHFVTGGPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDL YSYSFDGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDF NTDGFFFPVVSFSAGVKARFLLGGRHGDFKFLPPTGYSPCYEALLPKEKMHVEPVKDYKR DIEGVRDLLGTTKFLSQASFIPTPVDTSQIVLPPHLDNIRDKLAENIHELWGMNKIELGW TYGKVRDDNKRQHPCLVDFTKLPETERNYNLQMSSETLKTLLALGCHVAQVNVNAEDDLK KIKLPKDYMMSNGYKPAPLELSDVKLNAGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQ DLKTRRNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYNIDPPDQEALHTSDDQSIET IRFFRVEQTYAVKTGKWYFEFEALSGGDMRVGWARPGCRPDMALGVDDQAFVFDGLRGRR MHAGSRYFGLPWKEGDVVGCMINMEDKSMIFTLNGELMITGKGSELCFADFETEDGFIPV CSLGMSQIGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNRDITMWFSKRLPTFFNVPQD HVHIEVTRIDGTVDSPPCLKVTHKTYGTQNSNSDMVYCRLSMPVEFYSADKLLDESLKLS HPPKEDGGVNYGSITTYYHSVRVFAGQEPASVWVGWVTPDYHYYSKNFSLNKTRTVTVTL GDERGRVHESVQRSNCYMVCGADAVGPSSSSRSNSDLEIGCLIDLATGLVSFTANGKELP TTYQVEPNTKLFPAVFVRPTSANLFQLEFVKIKDAMPLSSAIFKSEHRNPVPQCPPRLDV QTIVAVMWSRMPNTFLSVETARVSERHGWVVQCLEPLEMMAVHIPEENRCLDILELSEHE DLRKFHYHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYNVLIS IHLETAKEARLMMNNEFIIPVTDETRSIKLFSDESKRHSLPGVGLSTSLKPRVNFSPVGI ISTKRHQFLYSPQIPLTNLKEKAISMLTEAVQGGGLHIRDPVGGSVEYQFVPILKLIGTL LIMGVLTSDEVRLILLLIAPIVFGEAKEGEEEKGDEAAAREKEEVSKNEEKAVEAGEEET KESKPPVKGLLKKSLPESVKRQMCELLHYFCDCELKHRIESIVSFSDSFVSKLQYNQKFR YNELMLAFNMSAAVTAKKTKEFRSPPHEQINILLNFSAGEDCPCPEEIQEELNSFHEELR LHCGIPVEEEEQEHDTSIKGRLLALLYKIKGPPQKTEEEPTETEQAVPTNLKELISQTIT SWAQESHIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDAINLLVSLGQIR SLLSVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEI AFPKMVASCCRFLCYFCRISRQNQKAMFDHLGYLLENSSVGLASEAMRGSTPLDVAASSV MDNNGLALALEEPDLEKVVTYLAACGLQSCAMLVAKGYPDIGWNPIEGERYLSFLRFVVF CNGESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAGMKEAIKIAEDPALDLPETPAG VPTGSGEEGGEVIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPT TDLVGIISITLKTPVANKDGTVTEPDMSACFCPDHKAPIVLFLDRVYGIEDQSFLLQMLE VGFLPDLRASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAHLFANTEHYVQLVDSTL QTIYRLSKGRSLTKAQRDSIEECLLAICKYIRPSMMQQLLRRLVFDVPMLTEYCNIPLKL LTNHYEQNWKYYCLPSGMGIFGTASEEELLLTKKLFWGIFDSLSQKKYDAKLFEMAKSCL CAIAGALPPDFVDASLGATLEKQASVDAQGNFDPKPINTANISLPEKLDYIAHKYAEHSH DKWSSEKMSAGWKHGDSVDEHAKTHPLLKPYKALSEKERETYRWPVKESLKSMLTMDWNI ERTKEGEAMFQQRESEKQRKISESQVNGFSPTPMDLHNVTLSRELQGMVEVVAENYHNIW AKKKKSELVSKGGGTHPLLVPYDTLTAKEKYRDREKAQDLFKFLQISGYVITRGLKDIEQ DSSSMEKRFAYKFLKRLLKYVDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLS DQTFKNQCLYFLSTPSKNLSSCGCASNKEKEMITSLFCKLAALVRHRISLFGSDSAMMVS CLHILAHSLDTRTVMKSGSELVKAGVRTFFESAAEDLEKLLEMLKLGKFMQSRAQMKSVT QSINYVTVALLPILSALFEHIRTYEFAMDLLLDDVQLSCYRILTCFYSLGTGKNVFVERH LPALGESLATLVAAMPVAFLEPHLNAHNPLSVFNTKTPRERAILSMPDTVEEMCPEMPRL DRLLKDVSDVSESGARYSDMPQVIEVILPMLCNYLSNWWEKGPENSLSDAQCCTMVTSEH HSIILGNILRILNNNLGIDDAPWMKRIAVYSQPIICKAGGALLRTHFLPTLDKLKKKTVK VVSEEELLKADAKSDNQEAELLILDEFSVLCRDLYAFYPMLIQYVDNNRSRWLKGPDADS TELFRMVAEIFILWCKSHNFKREEQNFVVQNEINNLGFLTGEGKTKMSKSGGDQERKHKR RRGEYYSVQTSLIIAALKKMLPIGLNMCTPGDQELISVAKIRYSLKDTDDEVKEHLRQNL HLQDKSDDPAVQWQLNLYKDVVVKSEEPADSEHTVDRVQSISAAVFYLEQVEQPLRNKKA VMHKLLSKQRKRAVVACFRMAPLYNLPRHRAINFFIPAYQRLWIEAEEYSFEEKLVQDLA KTPMKIVEEEEEEVAEIQPDPLHQLILHFSHNALTERSYLEEDPLYIAYADMMAKSCAED EEEEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLKLG IAILNGGNVQVQQKMLGYLKEKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMVTE EGSIHTQRGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTVDY LLRLQESISDFYWYYSGKDVIDETGKINFSKALSVAKQIFNSLTEYIQGPCIGNQQSLAH SRLWDAVVGFLHVFANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGTIGK QMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDNFREYDPECKGIISKKDFQKSMENQKQ YNQSEIEFLLSCAEADENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPYDSRLAT FLDLAESVLSYFEPYLGRIEIMGSAKRIERIYFEISESSREQWEKPQVKESKREFIFAVV NEGGESEKMEMFVNFCEDTIFEMQLASQISDSDMVEQPEEEEEEEGHSLLDELEGEEEDA LESASAFTTACRSVKTKIAHVRQIFSVKNVRKQFKKIKKLSLKEIITGFFSFFWMLFTGF FKGIYGLIFGFFHLIWSSMFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDVIEGEKVEA TESLGSPDTAMAPAGDIAEVDMMDMLTMPKKEGGKHVEPGLGDISELTAESSATDHKKKA AANPVETPENGTEKADTENQEKEDKPKQEEVKEPVVEEKPKARLSQPKEHAPTFMSNVFA VLDVYKNKMLNYLARNFYNLRFLALFMCFSINFILLFYKVTGETDEETDADNSWDGAEED EEDENTFFDMDEFVLQESSGYMLPTLRFLAIFHTVISMLCLVGYYCLKVPLVIFKREKEI ARKLEFDGLYITEQPTDEDIKGQWDRLVINTPSFPNNYWDKFIKRKVINKYGDMYGAERI AELLGLDKSALDFDPTVETVEKEASLLSWLSSIDTKYHIWKLGVVLTDNSFLYLIWYTTM SIFGHFNNFFFAAHLLDIAMCFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNF FRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDI TFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETH TLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPTGDCFRKQYEDQLG NT seq 14580 nt NT seq  +upstreamnt  +downstreamnt atggctgagggtggagaaggggaagatgagatccagttcttgagaactgatgacgaggtg gtgctgcagagtgcggccagcatccagaaggagcatcgcaagttctgcctggccgccgag ggactcggaaaccgcctgtgttacctggaatccacgtctgaagctaagcatgttcctcca gacctgtgcatctgtaactttgtgttggagcagtccctgtcagtgcgagccctgcaggag atgctggcgaacaccgggcagagcagcgaggggagtgctgaccatgaaaaatggaggttg attaaaaaggcgggtcagggcggtggacaccggacgctgctctacggccacgccatcctc ctacgccactccttcagtggcatgtacttgacctgtctgaagacatcgaggtctctgaca gacaagctgtcatttgatgtcggactacaagaggattcaataggagaggcctgctggtgg accattcaccctgcgtccaagcagagatccgagggagagaaagtccgtatcggagacgac ctgattctcgtcagcgtgtcgacggagagatacctgcatctctccatctccaacggcaac attcaggttgacgcctccttcatgcagaccctgtggaacgtccagccgacctgttcatcg gggaacatggctgtagggtttttgattggtggacatgtgatgcgtctctgtcatgggcac gatgagagtttgaccatccccggagcagacaagagtgaggaggagcagaggatagtcaac tatgaggcgggtaagggagcgtcgagggcccgctcactgtggcgactggagcctctccgg atcagctggagcggcagccacatccggtggggccaggccttccgactgcgccatctcgcc accggccactatctggccctgaccgaagaccgtggactggtcctgcaggacagagagaag tccgacacctcggccaccgctttctgtttcagggcctcgaaggaaaagggggactctggc ccaaagaaggacattgaaggtatggcagtgccggagatcaagtacggagactctgtctgc ttcatcatgcacttggagacaggactgtggctgtcctaccaggcgcctgacgccaaatcg tctcgtcttggtcccctgaaaagaagggcctgcctacattctgagggccacatggacgac gggctcaccctccagcgctgtcagcatgaggagtctcgggccgcgcgcatcatccgtaac tccacgttcctcttcaccaacttcatcaaggctttggacagaactgccgacggcgagtcc acggcggtggccgggtacgtcgaagaggtgctgcagacgctgaacgacttgatcgagtac tttaagcagcccgatttagagctggagcacgaggagaaacagtgtctcctccgttcactc atcaaacggcaggacctcttcaaagaggagggtatgctgagtctcttgtccaaatgcatt gaccggatgaacgtgtacaacagtgcagcccacttcggagagatggccggggaggaggcg ggcgcggcgtggaaggacatcctcaatctcctctatgaactgctggcgtcactgattcgt ggaaacaggaacaactgcacccagttttctcgcaacttggactggttggtcagcaaactg gagagactcgaatcttcatcaggaatcctggaagtcctccattgtatcttggtagaaagc ccagaggctctgaacatcatccagaaagggcacattaaatccatcatctctctgctctac aagcacggacgcaatcacaagattctggacgtcctgtgctccctctgtgtctgcaacggg gtggcggtgagaaccaatcagaacctgatctgtgacaacctgcttcccaagagggacctg ctgcttcagactcgactggtcaatgacgttcagagtatgaggcccaacatcttcctgggc atggctgaaggctcggctcagtataagaagtggtatttcgagctggtcatcgaccaggtg gaccactttgtgaccggagggccgacccacctgagggtcggctgggccaacacgaagggc tacgctccgtaccccggtggaggagaggggtgggggggcaacggcgtcggggacgacctg tactcctacagctttgatgggcttcatttgtggtcaggccgaatcccgagggccgtggcc tccattaaccagcacctgctgaactcggacgacgtggtcagctgctgtctggatctggga gctcccagcatgtccttcaggatcaacgggcagccggtccagggcatgttcgaggacttc aacaccgacgggttcttcttccccgtcgtcagcttctcagcaggtgtcaaagcccgtttc ctgttgggcggacgccacggagatttcaagtttttgccgcccaccggttactctccgtgc tatgaggcgctgctgccaaaggagaagatgcacgtggagcctgtgaaggactacaagagg gacatcgagggggtccgtgatctgctgggaaccaccaagttcctctctcaggcctctttc atccccacccctgtcgacaccagccagatcgttctgccccctcacctggacaacatccgg gacaagctggcagaaaacatccacgaactgtgggggatgaacaagattgaactgggctgg acctacggcaaggttcgtgatgacaacaagaggcagcacccttgccttgtggacttcacc aagctgcctgaaactgaaaggaactacaacctgcagatgtcgagtgaaacacttaagacc ctgttggctctgggatgccacgttgcccaggtcaacgttaatgctgaagatgatctgaag aaaatcaaattacccaaagactacatgatgtctaacgggtacaagcctgcgccactggaa ctgtctgacgtgaaactgaatgcaggtcaggaggttctagttgataaactggccgaaaat gcacacaatgtgtgggccaaagacagaattaaacaaggatggacctatggcatccagcag gatttgaagaccaggcgtaatcctcgcttggtgccgtatgctttactggacgaacgcacc aaaaaatctaacagagatagtctgcgagaggccatcaggactatggttggatacggatat aacatcgaccctccagaccaggaggccttgcacacgtccgatgatcagagcattgagacc atccgcttcttccgcgtggagcagacgtacgcggtgaagacagggaagtggtactttgag tttgaggcccttagtggaggagacatgagggtcggctgggcccgaccgggctgcagacct gacatggcgctgggagtggacgaccaagccttcgtctttgatggattaaggggtcgacgt atgcatgcaggcagccgctactttggacttccgtggaaggagggcgacgtggttggttgc atgatcaacatggaggacaaatccatgattttcaccctgaacggagagctcatgatcact ggcaaagggtctgagctttgcttcgctgactttgagacggaggacggtttcatcccggtg tgcagtctcggcatgtctcagatcggccgcatgaacctgggcaaggacgccagcaccttt aagtattacaccatgtgtggtctccaggaaggtttcgagccgtttgccgtcaacatgaac agagacatcaccatgtggttcagcaagcgcctgcccaccttcttcaacgtacctcaggac cacgtgcatattgaggtgacgaggatcgacggaacagtggacagccctccctgccttaag gtcacccacaagacttacggcacccagaacagcaacagtgacatggtctactgccgactg agcatgcctgtggagttctactctgcagacaagctgctggacgaatcactgaaactcagc caccctccgaaggaagatggaggtgtcaactacggaagcatcacaacttactaccactca gtgcgagtgtttgctggacaggaaccggcctcggtgtgggtgggctgggtcacacccgac tatcattactacagcaagaacttcagcctcaacaagacgcgtacagtcaccgtcaccctg ggagacgagaggggccgcgtccatgagagcgttcagaggagtaactgctacatggtgtgt ggagcagacgccgtcggcccgtcttcctccagccgctccaactctgacctggagatcggc tgcctgatcgacctggccaccggcctcgtctccttcactgccaacggcaaggagctgccc accacgtatcaggtggagccaaataccaaactcttcccagctgtgtttgtacgccccacc agtgcaaacctcttccagttagaatttgtcaagatcaaggatgccatgccgctctcgtcg gccatctttaagagcgagcacaggaacccggtgccacagtgtccgccacgactggatgtg cagaccatcgtggccgtgatgtggagccggatgccgaataccttcctcagtgtggagaca gctcgggtcagtgaaaggcacggctgggtggtccagtgcctggaacctctggagatgatg gctgttcatataccggaggagaacaggtgtttggatattctggagttatccgagcatgaa gacctacggaagttccactaccacacgctgaagctgtattgcgccctctgtgctctggga aacacgcgcgtagctcacgccctctgcagccatttggaccaatcacagctgctctacacc atcgacaaccaatacctctccggcatgctgagggagggcttctacaacgtcctcatcagc atccatcttgagacagcgaaggaggctcgcctaatgatgaacaacgagttcattatcccc gtgacggacgagacgaggtccatcaagctcttctccgacgagtccaagcgacactcgctg cccggcgttggcctgagcacctccctcaaacctcgggtcaacttctcgcccgtcggcatc atcagcacaaagcgccaccagttcctttacagcccccagatccccctgaccaatctgaaa gagaaggccatcagcatgcttacagaggccgtgcagggcggagggctccacatccgagac ccggtgggcgggagcgtcgagtaccagtttgttcccatcctgaagctgatcggaacactg ctgatcatgggagtcctaaccagcgacgaggtgaggctgatcctcctcctcatcgccccc atcgtgttcggcgaggccaaggagggcgaggaggagaagggggacgaggcggcggcgagg gagaaggaggaggtgagcaagaacgaggagaaggccgtggaggcgggcgaggaggagacc aaagagagcaaaccgcccgttaaaggcctgctgaagaagtcgctgcccgagtccgtcaaa cgccagatgtgcgagctgctgcactacttctgcgactgcgagctgaagcatcgcatcgaa tccatcgtctctttctccgactccttcgtctccaagctgcagtacaatcagaagtttcgc tacaatgagctgatgctggctttcaacatgtccgccgccgtcaccgccaagaagaccaaa gagtttcgctcgcccccacatgagcagatcaacatcctgttgaacttcagtgccggggag gactgtccctgccccgaggagatccaggaagaactcaactctttccatgaagagttgcga ctgcactgtggaattccagtggaggaggaagagcaagagcatgacacttcgataaaaggc cgcctcctcgctttgctctacaagatcaagggcccacctcagaagacagaagaggaaccc accgagacggaacaggctgttccaaccaacctgaaggagctgatctcccaaaccataacc agctgggctcaggagtctcacatccaggaccccgagctggtccgggtgatgttcagccta ctgaggaggcagtatgacggcatcggggagctgctccgggccatgaagaaatcctacacc atcagtgccgcgtccgtgcaggatgccatcaacctgttggtgtctctgggtcagatcagg tctctgctgtcggtgcgcatgggcaaggaggaggaaaaactcatgatcgacggactcggt gacatcatgaacaacaaggtattctaccagcatcccaatctgatgagagtgctgggcatg cacgagacagtcatggaagtcatggtcaacgtgctgggaggagacaagtcccaggagatt gccttccccaagatggtggccagctgttgtcgtttcttgtgctatttctgtcgcattagc cgccagaaccagaaagccatgtttgaccacctgggctacctgctggagaacagcagcgtc ggactggcctctgaagccatgcggggctccactccgctggatgtggcagcatcttcagtg atggacaacaacggcctggctctggccctggaggagcccgatctggagaaggtggtgacg tacctggccgcctgtggtcttcagagctgtgccatgctggttgccaagggttaccccgac atcggctggaaccccatcgaaggagagcgctacctatcgttcctcaggttcgtcgtcttc tgcaacggtgagagcgtggaggaaaatgccaacgtggtggtgaagctgctgatcagacgc ccggagtgtttcggccccgcgctgaggggagagggaggtcagggtctgctggctggcatg aaggaggccatcaagatcgctgaggatcctgccctcgacctgcccgagacccctgctgga gtccccactgggtctggtgaggagggaggagaagtgattcacatgggcaacgccatcatg tccttctactcggctctcattgacctgctgggacgctgcgcccccgagatgcatctcatc aacgcaggtaaaggtgaggcgctgcgcatcagagccatcctgcgctctctggttcccact acagacctggtgggcatcatcagcatcaccctcaaaacgcctgtggctaataaagatggc acagtgacagaacccgacatgtccgcttgcttctgtccggaccacaaggcccccatagtg ctcttcctggaccgagtgtacggcatcgaggaccagagcttcctgctccagatgttggaa gtcggcttcctgcctgacctccgagcctcggcgtcactggacacagaggtgctgagcacc acggagacggcgctggccatgaacaggtacatcggctcggcgctgctgccgctgctgacc cgctgcgcccacctcttcgccaacacggagcactacgtgcagctggtcgactccacgctg cagaccatctaccggctgtccaaaggccgctcgctcaccaaagcccagagggactccatc gaggaatgtctgctggctatctgcaagtatattcgtccctctatgatgcagcagctgctc agacgtctggtgttcgacgttcctatgctcaccgaatactgcaatataccgctgaagctg ctaaccaaccactatgagcagaactggaaatactactgtctgccgtcagggatgggcatc ttcggcacagcctccgaggaggagctccttctcaccaagaaactcttctgggggatcttt gactcactctctcagaagaagtatgatgctaaacttttcgaaatggccaagtcgtgcctg tgtgccatcgcgggagcgctgcctccggacttcgtggatgccagtttaggggcaacgctg gagaaacaggcttcagtggatgcgcagggaaactttgaccccaaacccatcaatactgcc aacatctcccttcctgaaaaacttgactacattgcccataaatatgcagagcattcccat gacaagtggtcctcagagaagatgtcggcaggctggaaacatggagacagtgtggatgag catgccaaaacccatccgctgctgaagccatacaaagctttgagtgagaaggagagagaa acgtaccgctggccagtaaaggagtccctgaagagcatgttgacgatggactggaacatc gagaggaccaaggagggagaagccatgttccaacaacgagagagcgaaaagcaacgaaag atctcagagtctcaggttaatggattctctccgactccaatggacctgcacaatgtcact ttgtctagagagttacagggcatggtggaggtggttgcagaaaattatcacaacatctgg gccaagaagaagaagtctgaactcgttagcaaaggaggagggacccacccgctgctggtt ccctatgacaccctgactgctaaagagaagtacagagacagagagaaggcccaggatctc ttcaagttcttgcagattagcggctatgttatcacgagaggtctgaaggacatagagcag gactcatcctccatggaaaagcgtttcgcctataagttcctcaagaggctgctgaagtac gtcgactctgcgcaggagttcatagctcatctcgaggccatggccaccagtgggaagaca gacaaatctcctcatgaccaggaaatcaagttcttcgccaaggtgctgcttcctctgtct gatcaaacctttaagaaccaatgcctctacttcctgtcgacgcccagcaagaacctgagc agctgtggctgtgcctccaacaaagagaaggagatgatcaccagcctgttctgtaagctg gcagctcttgtcagacacaggatttctctctttggaagtgattcggcgatgatggtgagc tgcctgcacatcctcgctcactcactcgacaccagaacagtgatgaagtccggctcggag ctggtcaaagccggggtcaggactttctttgagagcgcagccgaggatctggagaagctg ctggagatgctgaaactgggaaagttcatgcagtcccgcgctcagatgaagagcgtcacc cagagcatcaactacgtgacggtggcgctgctgcccatcctctccgccctctttgaacac atcagaacatacgagtttgcaatggacctgcttctggatgatgtgcagctgtcctgctac cgaatcctgacgtgtttctactctttggggacgggaaagaatgtctttgtggagcggcat ctgcctgcgctgggggagagcctggcgacgctggtggcagccatgcctgtagcgttcctg gagcctcatctaaacgcccacaacccactctccgtcttcaacaccaagacccctcgagag cgagccatcctgagtatgcccgacaccgtggaggagatgtgtccggagatgcctcgtctc gacaggctgctgaaagatgtcagcgatgtctctgagtctggtgctcgctacagtgacatg cctcaggtcatcgaggtgatcctccccatgctgtgtaactatctgtccaactggtgggag aaaggtccggagaactccctctcagatgcccagtgctgcaccatggtgacctctgagcac cacagcatcattctgggaaacatcctcaggatcctcaacaacaacctgggcattgatgac gccccctggatgaagaggatcgcagtctactctcagccaatcatctgcaaagccggagga gctctgctgaggacccacttcttgcccacactggacaaactgaagaagaagacagtgaag gtggtgtctgaagaggagctgctgaaggccgatgctaaaagtgacaaccaggaggcggag ctgctcatcctggatgagttctctgtgctctgcagggacctctacgctttctaccccatg ctcattcaatacgtggacaacaacaggtcgaggtggttaaaggggccggatgcagactcc actgagctcttcaggatggtggcggagatcttcatcctctggtgcaagtcacataacttt aaacgtgaggagcaaaactttgtggttcagaatgagatcaacaatttgggtttcctaacc ggtgaaggcaagacaaagatgtccaagtcgggtggagaccaggagaggaaacacaagcgc cgtcgtggtgaatattactccgtccagacgtctctgatcatagctgccctgaagaagatg ctgcccatcggcctcaacatgtgcaccccaggagaccaggagctcatctctgtggccaag atacgctacagtctgaaagacacagatgatgaggtgaaggagcacttgcgtcagaatcta catctccaggacaagtccgatgacccggcggtccagtggcagttgaacctgtacaaagac gtcgtggtgaagagcgaagaaccggcagactctgagcacacagtggaccgagtccagagc atctctgctgccgtcttctacctggagcaggtggagcaacctctgaggaacaagaaggct gttatgcataagctgctgtccaaacagcgtaagcgtgccgtggtggcgtgtttccgcatg gctccgctctacaatctacccaggcatcgtgctatcaacttcttcatcccggcctatcag agactttggatagaggcagaggagtactcctttgaggagaagctagttcaggatctggca aaaacccccatgaagattgtggaggaggaggaagaggaggtggctgagatccagcctgac cccctccaccaactcatcctccacttcagccacaacgctctgacagagagaagttacttg gaagaagatcctttgtatattgcgtatgcagacatgatggcaaagagctgtgcagaggat gaggaagaagaggaagaagggaaagagaagacatttgaggaaaaggagatggaaaagcag aagattctgtatcagcaggcgaggctgcatgctcgtggggcagcagagatggtgctgcag atgatcagcgccagtaaaggtcgtttgggccccatggtgacctgcaccctcaaactgggt atcgccatcttaaatggaggaaatgtgcaagttcagcagaaaatgcttggttacttgaaa gaaaaaagagatgcaggctttttcaagagtctctcaggactgatgcagtcctgcagtgtc ctggatttgaatgcgtttgagaggcagaacaaagcagaaggacttggcatggtgacagag gaaggttcaatccacactcagcggggctccaaggtactacagaacgatgagtttactaaa gatctgttccgctttttgcaacttctctgcgaggggcacaacggagatttccagaacttc ctaagaactcaaacaggaaacacaaccacagtcaacatcattatcagcaccgtggactat ctgctccgtctgcaggaatccatcagcgacttctactggtactactctggcaaagacgtc atcgatgaaacgggaaaaatcaacttctccaaagctttatctgtagccaagcagatattc aactcactcactgagtacattcagggcccgtgtattggcaaccagcagagtttagctcac agcagactgtgggatgcagtggtgggattcttgcacgtgtttgcaaacatgcaaatgaaa ctatcccaggatgccagtcagatcgagctattgaaggagctgatggacttacagaaggac atggttgtcatgttgctgtctctgcttgagggtaatgtggtgaatggaaccattggaaag cagatggtcgacacgctggtggagtcttccagcaatgtggagatgatcctcaagttcttc gacatgttcctcaagctgaaggatctcaccacctcggacaacttcagggagtatgacccc gagtgtaagggcattatttcgaagaaggacttccagaagtccatggagaaccagaagcag tacaaccagtcggagatcgagttcctgctctcgtgcgcggaggccgatgagaacgacatg ttcaactacaaggagttcgtggagcgattccacgagccggccaaagacatcggcttcaac gtggccgtgctgctgaccaacctgtctgagcacatgccctacgactcgcgcctcgccacc ttcttggatctggcagaaagtgtgctcagctactttgagccttacctgggtcgtattgaa atcatgggcagcgcgaagcgaatcgagaggatttacttcgagatcagcgagtcgagccgc gagcagtgggagaagccgcaggtcaaagagtccaagcgcgagttcatctttgccgtggtc aacgagggcggagagagcgagaagatggagatgtttgtgaacttctgcgaggacaccatc tttgagatgcagctggcctcacagatctccgactcggatatggtcgaacagcccgaagag gaggaggaggaagagggacacagcctcctggatgagctggaaggggaggaagaggacgcg ctggagtcggcctctgccttcaccactgcgtgtcgctcagtcaagacgaagatcgcgcac gtccgccagattttctctgttaaaaacgtacgcaagcagttcaagaaaataaagaagctg agcctcaaggagattatcaccggcttcttctccttcttctggatgctcttcactggcttc ttcaagggaatctacggcctcatcttcggtttcttccacctcatttggtcctccatgttc ggcggcgggctcgttgagggagccaagaacatcaaggtgacggacatcctcggaaacatg cctgacccgactcagtttggtatccacggagatgtgatagagggtgagaaagtggaggcc acagagtcattgggaagcccagacacagccatggcaccggcaggggacatcgcggaggtc gacatgatggacatgctgacgatgcctaaaaaagaaggcggaaaacacgtggagcccggc ctgggagatatttctgagctgactgccgagtcctccgccactgatcacaagaagaaagct gctgccaatcctgttgaaacccctgagaatggaacagagaaagcagacacagagaaccag gagaaggaggataagccgaagcaggaggaggtgaaggagcctgtggtggaggagaagccc aaggccagattgagtcagcctaaagagcatgcacctaccttcatgtccaacgtctttgct gtcctggacgtctataagaacaagatgctgaactacctggctcgtaacttctacaacctc cgtttcctggctctgttcatgtgcttctccatcaacttcattctgctcttctacaaggtc actggcgaaaccgatgaggaaaccgacgcggacaacagctgggatggcgctgaggaggac gaggaggacgagaacacgttcttcgacatggacgagtttgtgcttcaggagagcagcggc tacatgttgccgaccctgaggttcttggccattttccacaccgtcatctccatgctctgc ctggtcggctactactgcctgaaggttcctctggtgattttcaagagagagaaggagatc gccaggaagcttgaatttgatggcctctacatcactgagcagccgactgacgaggacatc aaaggccagtgggatcgactcgtcatcaacaccccgtccttcccaaacaactactgggac aagtttatcaagcgcaaggtgattaacaaatatggtgacatgtacggggctgaacgcatc gctgagctgttgggcctggataagagtgctctggactttgaccccacggtggagacggtc gagaaggaagcgtccctgctgtcctggttgagctccattgatacaaagtaccacatctgg aaactgggcgtggttttgactgacaactccttcctgtatctgatctggtacaccaccatg tccatctttggacacttcaacaacttcttcttcgctgctcatctgctcgacatcgccatg tgcttcaagaccctccgcaccatcctgtcgtccgtcactcacaacggcaagcagctcgtg ctgacggtgggtctgctggccgtggtcgtctatctctacaccgtggtggccttcaacttc ttcaggaagttctacaataagagcgaggacgaggacgagcccgacatgaagtgtgacgat atgatgacgtgctacctgttccacatgtacgtgggcgtgagagccggaggaggcatcgga gacgagctggaggacccggccggagatccctacgagctctaccgcatcctgtttgacatc accttcttcttcttcgtcatcgtcatcctgctggccatcattcagggtttgatcatcgac gccttcggagagctgagagaccagcaggagcaggtgaaggaggacatggagaccaaatgc ttcatctgcggaatcgggaacgactacttcgaccggacgcctcacgggttcgaaacccac accttacaagaacacaacctcgccaactacctgttcttcctgatgtacctgatcaacaag gatgagactgaacacacgggtcaggagtccttcgtgtggaagatgtaccaggagagatgc tgggacttcttcccgaccggagactgcttccgtaagcagtatgaggaccagctgggttag

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