Escherichia coli W: ECW_m4131
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Entry
ECW_m4131 CDS
T02002
Symbol
metE
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
elw
Escherichia coli W
Pathway
elw00270
Cysteine and methionine metabolism
elw00450
Selenocompound metabolism
elw01100
Metabolic pathways
elw01110
Biosynthesis of secondary metabolites
elw01230
Biosynthesis of amino acids
Module
elw_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
elw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ECW_m4131 (metE)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
ECW_m4131 (metE)
Enzymes [BR:
elw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
ECW_m4131 (metE)
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Gene cluster
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Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
ADT77449
UniProt:
E0J3W6
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Position
4237585..4239846
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AA seq
753 aa
AA seq
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MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELRARHWDQQKQAGIDLLP
VGDFAWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFN
TNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHNVKPVLLGPVTYLWLGKVKGEQFDR
LSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLL
TTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRAD
LTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLR
DALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRAR
FKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVL
VHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYA
QSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDE
PALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDAD
VITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERL
WVNPDCGLKTRGWPETRAALANMVQAAQNLRLG
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atgacaattcttaatcacaccctcggtttccctcgcgttggcctgcgtcgcgagctgaaa
aaagcgcaagaaagttattgggcggggaactccacgcgtgaagaactgctgacagtaggg
cgtgaactgcgtgctcgtcactgggatcaacaaaagcaagcgggtatcgacctgctgccg
gtgggcgattttgcctggtacgatcatgttctgaccaccagtctgctgctgggtaatgtt
ccgccacgtcatcagaacaaagacggttcggtagatatcgacaccctgttccgtattggt
cgtggacgtgcgccgactggcgaacctgcggcggcagcggaaatgaccaaatggtttaac
accaactatcactacatggtgccggaattcgttaaaggccaacagttcaaactgacctgg
acgcagctgctggaggaagtggacgaggcgctggcgctgggccacaacgttaagcctgtg
ctgctggggccggttacttacctgtggctggggaaagtgaaaggtgaacagtttgaccgc
cttagcctgctgaacgacattctgccggtttatcagcaagtgctggcagaactggcgaaa
cgcggcatcgagtgggtacagattgatgaacccgcgctggtactggaactaccacaggcg
tggctggacgcatacaaacccgcttacgacgcgctccagggacaggtgaaactgctgctg
accacctattttgaaggcgtaacgccaaatctcgacacgattactgcgctgcctgttcag
ggtctgcatgttgacctcgtacatggtaaagatgacgttgctgaactgcacaagcgcctg
ccttctgactggttgctgtctgcgggtctgatcaatggtcgtaacgtctggcgcgccgat
cttaccgagaaatatgcgcaaattaaggacattgtcggcaaacgtgatttgtgggtggca
tcttcctgctcgttgctgcacagccccatcgacctgagcgtggaaacgcgtcttgatgca
gaagtgaaaagctggtttgccttcgccctacaaaaatgccatgaactggcactgctgcgc
gatgcgctgaacagtggtgacacggcagctctggcagagtggagcgccccgattcaggca
cgtcgtcactctacccgcgtacataatccggcggtagaaaagcgtctggcggcgatcacc
gcccaggacagccagcgtgcgaatgtctatgaagtgcgtgccgaagcccagcgtgcgcgt
tttaaactgccagcgtggccgaccaccacgattggttctttcccgcaaaccacggaaatt
cgtaccctgcgtctggatttcaaaaagggcaatctcgacgccaataactaccgcacgggc
attgcggaacatatcaggcaggccattgttgaacaggaacgtttgggactggatgtgctg
gtacatggcgaggccgagcgtaatgacatggtggaatactttggcgagcacctcgacggg
tttgtctttacgcaaaacggttgggtacagagctacggttcccgctgcgtgaagccaccg
attgttattggtgacgttagtcgcccggcaccgattaccgtggagtgggcgaagtatgcg
caatcgctgaccgacaaaccggtgaaagggatgctgacggggccggtgaccatactctgc
tggtcgttcccgcgtgaagatgtcagccgtgaaaccatcgccaaacagattgcgctggcg
ctgcgtgatgaggtggccgatctggaagcggcagggattggtatcatccagattgacgaa
ccggcgctgcgcgaaggtttaccactgcgtcgtagcgactgggacgcctatctccagtgg
ggcgtagaggccttccgtatcaacgccgccgtggcgaaagatgacacacaaatccacact
cacatgtgttattgcgagttcaacgacatcatggattccattgcggcgctggatgcagac
gtcatcaccatcgaaacctcgcgttccgacatggagttgctggagtcgtttgaagagttt
gattatccgaatgaaatcggtccaggcgtctatgacattcactcgccaaacgtaccgagc
gtggaatggattgaagccctgctgaagaaagcggcaaaacgcattccggcagagcgcctg
tgggtcaacccagactgtggcctgaaaacgcgcggctggccagaaacccgcgcggcactg
gcgaacatggtgcaggcggcgcagaatttgcgtctggggtaa
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