Escherichia marmotae: C1192_12540
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Entry
C1192_12540 CDS
T05353
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ema
Escherichia marmotae
Pathway
ema00300
Lysine biosynthesis
ema00550
Peptidoglycan biosynthesis
ema01100
Metabolic pathways
ema01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ema00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C1192_12540
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C1192_12540
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C1192_12540
Enzymes [BR:
ema01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C1192_12540
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AUT27842
LinkDB
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Position
complement(2429282..2430640)
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AA seq
452 aa
AA seq
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MISVTLSQLANILNGELKGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVNDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFTGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKTGLANLQAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESDACHLQVGEAAKAAGIDRVLSVGKQSHAISTASGAGEHFADKSALITRLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagtgtaacccttagccaactggcgaatattctcaacggcgaactgaaaggggct
gatatcacccttgacgccgtaaccaccgatacccgtaaattgacgcctggctgtctgttc
gtcgccctgaaaggcgaacgtttcgatgcccatgattttgccgaccaggcgaaagctgga
ggggcgggcgcgctgctggttagccgtccgctggatatcgacctgccacagttaatcgtt
aacgatacgcgtctggcatttggtgaactggcagcatgggttcgtcagcaagttcctgct
cgtgtggttgccctgaccggttcctccggtaaaacctccgtgaaagagatgaccgcggcg
attttaagtcagtgtggcaacacgctttatacggctggcaatctcaacaacgacatcggc
gtgccaatgacgctgctgcgtttaacgccggaatacgattacgcggtcattgagcttggc
gctaaccatcagggcgaaattgcctggactgttagcctgacccgtccggaagccgcactg
gtcaacaatctggcggctgcgcatctggaaggtttcggctcgcttgcgggtgtcgcgaaa
gcgaaaggcgaaatctttaccggcctgccagaaaacggtatcgctatcatgaatgccgat
aacaacgactggctgaactggcagagtgtgattggctcacgcaaagtgtggcgtttttcg
ccaaatgccgccaacagcgattttaccgctaccaatatccatgtgacttcacatggtact
gaatttacgctgcaaaccccaacaggtagcgtcgatgttctgctgccgctgccggggcgt
cacaatatcgcaaatgcgttggctgccgcggcgctctccatgtccgtgggtgcaacgctt
gatgccatcaaaacgggactggcaaatctgcaagctgttcctggtcgtcttttccccatt
caactggcggaaaaccagttgctgctcgacgactcctataacgccaatgttggctcaatg
accgccgcagttcaggtactggctgaaatgccgggttatcgcgtgctggtggttggtgat
atggccgagctgggtgctgaaagtgatgcctgtcatctccaagtgggggaagcggcgaag
gcggctggtattgaccgcgtgttaagcgtgggcaagcaaagccatgctatcagcaccgcc
agcggtgctggcgaacattttgctgataaatccgcgttgattacgcgtcttaaatcactg
attgcagagcaacaggtgattacgattttagttaagggttcacgtagtgctgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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