KEGG   Eublepharis macularius (Leopard gecko): 129336255
Entry
129336255         CDS       T09084                                 
Symbol
CAD
Name
(RefSeq) LOW QUALITY PROTEIN: CAD protein
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
emc  Eublepharis macularius (Leopard gecko)
Pathway
emc00220  Arginine biosynthesis
emc00240  Pyrimidine metabolism
emc00250  Alanine, aspartate and glutamate metabolism
emc01100  Metabolic pathways
emc01240  Biosynthesis of cofactors
Module
emc_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:emc00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    129336255 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    129336255 (CAD)
   00220 Arginine biosynthesis
    129336255 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:emc01002]
    129336255 (CAD)
Enzymes [BR:emc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     129336255 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     129336255 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     129336255 (CAD)
Peptidases and inhibitors [BR:emc01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   129336255 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   129336255 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 MGS Dala_Dala_lig_C ATP-grasp ATPgrasp_Ter DHOase Amidohydro_1 ATP-grasp_3 GARS_A Peptidase_C26 GSH-S_ATP Xre-like-HTH
Other DBs
NCBI-GeneID: 129336255
NCBI-ProteinID: XP_054845335
UniProt: A0AA97JTZ5
LinkDB
Position
1:224766021..224818352
AA seq 2240 aa
MGSLVLEDGTVLRGRFFGAAGAAAAGEVVFQTGMVGYPEALTDPSYKSQILVLTYPLIGN
YGVPPDELDQCGLSRWFESSRIHVAALIVGECSRSSSHWSATRSLDQWLQENGIPGLEGV
DTRALTKRIREKGTLLGKLVPDGIHNQSLPFEDPNKRHLVKEVSLKAPQVFNSGGSVRIT
AVDCGLKYNQIRCLCQRGAAVTVVPWDHPLDSAEFDGLFISNGPGDPVLCQATVANLRHV
LELQTPKPVFGICLGHQLLALAIGAKTYKMKYGNRGHNQPCLYEGSQRCFITSQNHGFAV
DPASLPAGWSPLFTNANDRSNEGLVHDSKPFFSVQFHPEHNAGPMDLECLFDVFLETVRD
LVAGGQNSKTVHERLQNYLRSAEAPLASDVSRPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEESIQTVLINPNIATVQTSKGLADKVYFLPITPDYVTQVIKNERPDGILLTFGGQT
ALNCGVELTKAGVLERYHVRVLGTPVASIEMTEDRKVFVEKMEEIGEHVAPSEAACSVEQ
AQAAAERLGYPVLMRSAYALGGLGSGFANGREELTALVSQAFAHTSQVLVDKSLKGWKEI
EYEVVRDAYDNCITVCNMENLDPLGIHTGESIVVAPSQTLNDREYNLLRTTAIKVVRHLG
IIGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPVLRN
SVTNSTTACFEPSLDYCVVKIPRWDLSKFLRVSTKIGSSMKSVGEVMAIGRSFEEAFQKA
LRMVDENCVGFDHTVKPVSDMELETPTDKRIFVLAAALRAGYSIERLYELTKIDRWFLHK
MKNIADHALCLESYRQAEPGAMPAAVLKLAKQLGFSDKQVAQAVLSTELAVRKMRHDLKI
LPVVKQIDTVAAEWPAQTNYLYLSYNGTDHDLAFREPHVMVIGSGVYRIGSSVEFDWCAV
GCIQELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEMSFEVVMDIYELENPEGVILSMG
GQLPNNIAMALHRQQCRILGTSPEAIDSAENRFKFSRLLDTINISQPLWKELSDMESAKQ
FCCKVGYPCVVRPSYVLSGAAMNVAYSDSDLERFLSNAVAVSKEQPVVISKFIQEAKEID
VDAVACDGVVVAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAIGQELQVT
GPFNLQLIAKHDQLKVIECNVRVSRSFPFVSKTLGVDLVALATQVIVGEEVEPVGLMAGT
GIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRCEAYLKAMLSTGFKIPKKNIL
LTIGSYKNKSELLPTVRTLESLGYNLYASLGTADFYTEHGIKVRAVDWHFEEADGSEIPG
KDTQQRSILDYLAENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRLAVDYSVPLIIDIKC
TKLFVEALGQIGGPPPLKMHVDCMTSQKLIRLPGLIDVHVHLREPGATHKEDFASGTAAA
LAGGITMVCAMPNTTPAVIDAASFALVQKLAETGARCDFALYVGASSDNAGSLGPVAGLA
AGLKMYLNDTFSDLKMDNVSLWMEHFEKWPKHLPIMAHAEKQTVAAILMVAQLYQRPVHI
CHVAHKEEILIIKAAKQKGIEVTCEVAPHHLFLCQEDLGRIGEGRGQVRPMLGTREDMEA
LWDNLDTIDCFATDHAPHTLEEKLGKDPPPGFPGLETMLPLLLTAVSEGRLTVEDIVKRL
YENPRRIFGLPVQEDTYIEVDLEQEWLVPTYTAFSKSRWTPFEGMRVKGTVRRVILRGEV
AYIDGQVLVPPGYGQDVRKWPTGTVVPHPAPTKEILKTPERPRPTVQAEALRSRASSPRR
AGPVGDARFHLPPRIHRASDPGLPAEDLREKAVKKATEPDLTMIQDGSLYLAGPLPRQTS
PQSLPHPQTSPLLHPLVGQHVLSVKQFTKDQMSHLFNVAHNLRMMVQKERSIDILKGKVM
ASMFYEASTRTSSSFAAAMYRLGGSVLTFSEATSSCQKGESLADSVQTMSCYSDVLVLRH
PQPGAVELAAKHCRKPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGR
TVHSLACLLTQYRVSLRYVTPRNLRMPSDVFHFVASKGIKQEEFENIEEALPDTDVLYMT
RIQKERFSSIQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFR
QAENGMYIRMALLATVLGRY
NT seq 6723 nt   +upstreamnt  +downstreamnt
atgggcagcctggtgctggaggacgggacggtgctgcgcgggcgcttcttcggggccgcg
ggggccgccgctgccggggaagtggtcttccagacgggcatggtgggatatcccgaagca
ctgacggatccctcctacaaatcccagatcttggtactaacgtatcctctcattgggaac
tatggcgttcctcctgatgaattggaccagtgtggactcagccggtggtttgagtccagt
cgcatccatgtggccgcgctgattgtgggcgagtgctctcgcagctccagccactggagt
gccacacgctcgcttgaccagtggctacaggagaatggaattcctggcctggaaggagtg
gacacacgagcactgactaagaggattcgggaaaaggggacattgctgggcaaattggta
ccagatggcatccataaccagagcctgccctttgaggatccaaacaagaggcacctggtg
aaggaagtctcattgaaggcaccccaggtattcaattctggtggttcagtgcgaatcaca
gctgtggactgtggcttgaagtacaaccagatccggtgtttgtgtcaacgtggtgcagct
gtgactgtagtgccttgggatcacccactggacagtgcagaatttgatgggctttttatc
agcaatgggcccggggacccagtgttatgccaagctactgttgccaacctgcgccatgtt
ttggaactgcagacccctaagcctgtctttggcatctgcttgggccatcagctgctagca
ttggccattggggctaagacctacaagatgaagtatgggaaccgtggacacaaccaacca
tgcctttacgagggctctcagcgctgttttatcacctcccagaaccatggctttgcagtg
gaccctgctagcttgccggctggctggtcacctctcttcacaaatgccaacgaccgctct
aatgagggccttgtgcatgattcaaagcccttcttcagtgttcagttccacccagagcac
aatgctggcccaatggaccttgagtgtctttttgatgtcttcctggagaccgtgcgtgac
ctggttgctggagggcagaattccaagacagtgcatgagaggctgcagaactacctgcga
tctgcagaagccccgcttgccagcgatgtgtcccggccccgtaaggtgttaattctgggc
tctgggggcctttcgatagggcaggcgggtgagtttgactactctggctcccaggctatc
aaagccctgaaggaagaaagtatccagactgtgctgatcaaccccaacattgccacggtg
cagacctccaagggcctggctgacaaggtctacttcttgcccatcacccctgactatgtc
acccaggtgataaagaatgagcgtccagatggtatcctgctgacctttggaggacagact
gcactgaactgtggtgtagaactgaccaaggctggcgtgctggaacggtaccatgtccgt
gtcctgggcacccctgtggcctccattgagatgactgaggaccgcaaggtctttgtggag
aagatggaggagattggagaacatgtggcacccagcgaagctgcctgctccgttgaacag
gctcaagcagcggctgaacggctcggctacccagtgctcatgcgttcggcctatgcgctg
ggtgggctgggctctggcttcgccaatggcagagaggaactgacggctcttgtgagccag
gccttcgcccacacctcacaggtgctggtggacaaatcgctcaaaggatggaaagagata
gagtatgaagtggttcgagatgcctatgacaactgcatcacggtgtgtaatatggagaac
ttggatccgctgggcatccacactggggaatctatcgtggtagcccccagccagacacta
aatgaccgggagtacaacctgctgcgcaccacagccatcaaggtggttcggcacctgggg
attattggcgaatgcaacatccagtatgcactgaaccctgagtctgagcagtactacatc
atcgaggtgaacgcccggctctcgcggagttctgcattggcaagcaaagccaccggctat
cccttggcctacgttgctgccaagctggctttgggcatccctttgcctgtactgaggaat
tctgtcaccaactccaccacagcctgctttgaacccagcctggattactgtgttgtcaag
attccacgctgggatctcagcaaatttctgcgtgtcagcaccaagattggcagctcaatg
aagagtgtgggtgaggttatggccattggtaggagctttgaggaggccttccagaaggca
ctgcgcatggtggatgagaactgtgtagggtttgaccacacagtgaaaccggtctctgac
atggagctggagactcctactgacaagcggatcttcgtcctggctgctgccctgagggcc
ggctactccatcgagcgcctttatgagctcaccaagattgaccgctggttcctgcacaag
atgaagaacatcgctgaccacgccctgtgcctggagtcgtaccgccaggctgagccgggt
gccatgccagctgcagtgctgaagctggcaaagcagctgggcttctcagacaagcaggtg
gctcaagctgtgctcagtacagaattagctgtgaggaagatgcggcatgacctgaagatc
ctgccggtggtgaaacagattgacacagtggcggccgagtggccggcccagaccaactac
ctctacctcagctacaacggaactgaccacgacctggccttccgtgagccgcacgtcatg
gtcattggctctggtgtctaccgcattggcagtagcgtcgagttcgactggtgtgctgtt
gggtgtatccaggagctgcgcaagatgggctacaaaactatcatggtgaactacaaccct
gagacagtgagcacagactacgacatgtgtgaccgtctctacttcgatgagatgtccttc
gaggtagtgatggatatctatgagctagagaaccccgagggtgtgatcctgtccatggga
gggcagctgcccaataacattgccatggcactgcaccggcagcaatgcagaatcctgggc
acttcccctgaggctatcgactctgctgaaaaccgtttcaagttctcccgccttctggac
accatcaatatcagccagcccctctggaaggagctgtcggacatggagtcagccaaacag
ttctgctgcaaggtggggtatccctgtgtggtgcgcccctcctatgtgctcagtggtgct
gccatgaatgtggcctactcagacagtgacttggagaggttcctcagcaatgccgttgcc
gtctccaaggagcagccagttgtcatctctaagttcatccaggaggccaaggagattgat
gtagatgctgtggcctgcgatggggtggtagtggccattgcgatctctgagcacgtggag
aatgctggcgtgcactcgggggatgccacactggtgacgcctccacaggacatcacacca
aagaccctggagcggatcaaggccattgtgcatgccattgggcaagaactgcaggttacg
gggcccttcaatctccagctcattgccaagcatgaccagctgaaggtgatcgagtgcaac
gtgcgtgtatcccgctccttcccctttgtctctaagacgctgggtgtcgatctggtagct
cttgccacacaggtgatcgtaggagaggaggtagagcctgtggggctcatggcaggcacc
ggcatcgttggtgtcaaggtaccccagttttcattctcacggctggcgggtgctgatgtt
gtgctgggcgtggagatgaccagcacgggtgaggtagcctgctttggcgagaaccgttgt
gaggcctacctcaaagccatgttgagcactggcttcaagatccccaagaagaacattctg
ctgaccattgggagctacaagaacaagagcgagctcctgcccacggtgcgcaccttggag
agcctaggctacaacttgtatgccagcctgggtactgctgacttctacacagagcatggc
atcaaggtgagggccgtggactggcactttgaggaggccgacggcagcgagataccaggc
aaggatacgcagcagcgcagcattttggactacttggctgagaatcactttgacttggtg
atcaacctgtccatgcgcaactcgggtgggcgccggctctcctccttcgtcaccaaagga
taccgcacccggcgcttggctgtggactactctgtgcccctcatcattgatatcaagtgc
accaagctctttgtcgaggcattgggccagatcgggggccctcctccactgaagatgcac
gtggactgcatgacctcacagaagctcatccgcttgccaggactgatagatgttcatgtg
catttgcgtgagccaggggccacccacaaagaagactttgcctctggcacagctgctgcc
ctggctggaggcatcaccatggtgtgtgccatgcccaataccactcctgctgtcatcgat
gcggcatcctttgccctggtgcagaagttggcagagacaggggcccgctgtgactttgca
ctgtatgtgggagcctcttctgacaatgctggctctctggggcctgtggccggactcgct
gctggcctcaagatgtatctgaatgacaccttctctgacctcaagatggataacgtttct
ttgtggatggagcattttgaaaaatggcccaagcaccttccaattatggcacacgctgag
aaacaaacagtggctgccatactgatggtagcccagctgtaccagcgccctgtccatatc
tgccatgtggcccacaaagaggagatcttgatcatcaaggctgcaaagcagaagggcatt
gaggtgacatgtgaggtggcccctcatcacctcttcctgtgccaggaggacctagggcgc
attggagaaggccggggacaggtacggcccatgctgggcacccgcgaagacatggaagca
ctctgggacaacctggacaccattgactgttttgccacagaccatgctccacacacactg
gaggagaagcttgggaaggaccctcctcctggcttcccaggactggagaccatgcttccc
ctcttgctgacagctgtgtctgaggggcgcctcactgtggaagatattgtcaagcgcctg
tatgagaacccccggcggatctttggcctgcctgtgcaggaggacacctacattgaggtg
gatctggaacaggagtggctggtgcccacctacacagccttcagcaagtcccggtggaca
ccattcgaaggaatgcgggtgaaggggactgtccggcgtgttatcctacgtggagaggtg
gcctacatcgatgggcaggtccttgtacccccaggctatgggcaggatgtgcgaaaatgg
ccaacgggcacagtagttcctcatccagctccaaccaaggagatcctgaagacccctgaa
cgcccccgccccactgtgcaagcagaggccttgcgcagccgagcatcaagtccccgccga
gcaggcccggtgggagatgcacgcttccatctgccaccccgcatccaccgtgcctcagac
cctgggctaccagctgaagatctcagggaaaaagctgtcaagaaagcaactgagcctgac
ttgaccatgatccaagatggctcactttacctggcaggccccttgcccagacagacgtcc
ccccagagcctgccgcacccacagacctcaccattgcttcaccctcttgtcgggcagcat
gtgctgtcagtcaaacagttcacaaaagatcagatgtctcacctgttcaatgttgcacac
aacctgcgcatgatggtgcagaaggagcgcagcatcgacatcctaaaggggaaggtgatg
gcgtcgatgttctatgaagccagcacacgtaccagcagctcctttgctgcagccatgtac
cgcttgggtggttctgtgctcaccttctctgaagccacttcatcttgccagaaaggagag
tcgctggctgactcggtccagaccatgagctgctactcagatgtccttgtgctgagacac
ccccagccaggtgcagtagagctggctgccaagcactgccgcaaacctgtgatcaatgct
ggcgatggagttggggagcatccaacacaagccctgttggacatcttcaccatccgcgag
gaactgggcaccgtcaatggcatgacaataaccatggtgggtgacctgaaacacgggcgc
acagtccactctttggcctgtctgctgacccagtaccgtgtcagcttgcgctacgtcact
cctcgtaacctgcgcatgccatctgatgtcttccattttgtggcctccaaagggatcaag
caggaggagtttgagaacattgaggaggcccttcctgatactgatgtgctctacatgacc
cgcatccagaaggagcgcttttcctccatccaggagtatgaggcatgttttgggcagttc
atcctgaccccacacatcatgaccagggccaagaagaagatggtggtgatgcacccaatg
ccccgagtcaacgagatcagcgtggaggtggattcggacccccgggcagcctacttccgg
caggcagagaatggcatgtacatccgcatggcactgttggccacggtgcttggccggtac
tga

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