Eulemur rufifrons (Bennett's brown lemur): 138393376
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Entry
138393376 CDS
T11398
Name
(RefSeq) calpain-2 catalytic subunit
KO
K03853
calpain-2 [EC:
3.4.22.53
]
Organism
eruf Eulemur rufifrons (Bennett's brown lemur)
Pathway
eruf04141
Protein processing in endoplasmic reticulum
eruf04210
Apoptosis
eruf04217
Necroptosis
eruf04218
Cellular senescence
eruf04510
Focal adhesion
eruf05010
Alzheimer disease
eruf05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
eruf00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
138393376
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
138393376
04217 Necroptosis
138393376
04218 Cellular senescence
138393376
09144 Cellular community - eukaryotes
04510 Focal adhesion
138393376
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
138393376
05022 Pathways of neurodegeneration - multiple diseases
138393376
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
eruf01002
]
138393376
Enzymes [BR:
eruf01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.53 calpain-2
138393376
Peptidases and inhibitors [BR:
eruf01002
]
Cysteine peptidases
Family C2: calpain family
138393376
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NCBI-GeneID:
138393376
NCBI-ProteinID:
XP_069340600
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Position
11:1291668..1328265
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AA seq
700 aa
AA seq
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MAGIAAKLARDREAAEGLGSHERAVKYLNQDYGALRDECLEAGTLFQDPAFPAIASSLGF
KELGPYSSKTRGIEWKRPTELCADPQFIVGGATRTDICQGALGDCWLLAAIASLTLNEEV
LARVVPLDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL
LEKAYAKVNGCYEALSGGATTEGFEDFTGGIAEWYELQKPPANLFRIIQKALQKGSLLGC
SIDITSAADSEAVTFQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGEVEWTGRWNDN
CPNWNTVDPEVRERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK
MDGSWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDQEDGESGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEELSGQTNIHLGKKFFLTTRARERSDTFINLREVLNRFKLPPG
EYILVPSTFEPHKDGDFCVRVFSEKKADYQAVDDEIEADLEEVDVSEDDIEDGFRKLFSQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLREFYIL
WTKIQKYQKIYREIDVDRSGTMNSYEMRRALEEAGFRLPCQLHQVIVARFADEELIIDFD
NFVRCLVRLETMFKIFKQLDPENTGTIELNLISWLCFSVL
NT seq
2103 nt
NT seq
+upstream
nt +downstream
nt
atggcgggcatcgcggccaagctggcgcgggaccgggaggcggccgaggggctgggctcg
cacgagagggccgtcaagtacctgaaccaggactacggggcgctgcgggacgagtgcctg
gaggccgggacgctctttcaggaccccgccttccccgccatcgcgtcgtccctgggcttc
aaggagctgggaccctactccagcaaaacccggggcatcgagtggaagcgacccacggag
ctctgcgctgacccccagtttattgtcggaggagccacccgcacagacatctgccaagga
gccctgggtgactgctggctgctggcggccatcgcctccctcaccttgaacgaagaagtc
ctggctcgagtggtccccttggaccagagcttccaggaaaactacgcagggatcttccac
ttccagttctggcagtacggcgagtgggtggaggtggtcgtggacgacaggctgcccacc
aaggacggggagctgctctttgtgcattcggccgagggcagcgagttctggagcgccctg
ctggagaaggcctacgccaaggtcaacggatgctacgaagcgctctcggggggtgccacc
accgagggcttcgaggacttcaccggaggcatcgccgagtggtacgagctgcagaagccc
cctgccaacctgttcaggatcatccagaaggctctgcagaaaggctcgctcctcggctgc
tccatcgacatcaccagcgccgcggactcggaggccgtcacgttccagaagctggtgaag
ggacacgcgtactccgtcaccggcgccgaggaggttgaaagcagcggaagcctgcagaag
ctgatccgcatccgcaacccctggggagaagtggagtggacgggcaggtggaatgacaac
tgcccaaactggaacacggtagacccggaggtgagggaaaggctgaccagacgccatgaa
gacggggagttctggatgtctttcagtgacttcctgcgtcactattcccgcctggagatc
tgcaacctgacccccgacaccctcaccagcgacacctacaagaagtggaaactcaccaag
atggacgggagctggaggcgcggctccaccgcgggcggctgcaggaactacccgaacact
ttctggatgaaccctcagtacctgatcaagctggaggaggaggacgaggaccaggaggac
ggcgagagcggctgcaccttcctggtggggctcatccagaagcaccggcggcggcagagg
aagatgggcgaggacatgcacaccatcggcttcggcatctacgaggtcccggaggagttg
tccgggcagaccaacatccacctgggcaagaagttcttcctgaccacgcgcgcccgcgag
cgctccgacaccttcatcaacctccgcgaggtgctgaaccgcttcaagctgccgccgggg
gagtacatcctcgtgccctccaccttcgagccccacaaggacggcgacttctgcgtccgc
gtcttctccgaaaagaaagccgactaccaagccgtcgatgatgaaatcgaggccgacctt
gaagaggtcgacgtcagcgaggacgacatcgaggacgggttcaggaagctgttcagccag
ttggcaggggaggacgccgagatctctgccttcgaactgcagaccatcctgaggagagtt
ctagcaaagcgccaagatatcaaatcagacggcttcagcatcgagacctgcaaaatcatg
gtcgacatgctggactcggacggcagcggcaagctggggctgagggagttctacattctc
tggacgaagattcaaaagtaccaaaaaatttaccgggaaatcgacgtagacaggtctggt
accatgaattcctacgaaatgcggagagcgttagaagaagcaggtttcaggctgccctgc
cagctccaccaggtcatcgtggcccggtttgcagacgaggagctcatcatcgacttcgac
aatttcgttcgctgtctggttcggctggaaacgatgttcaagatattcaagcagctggac
cccgaaaacaccgggaccatagagctcaacctcatctcctggctctgtttttcagtactt
tga
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