Escherichia coli O17 K52 H18 UMN026 (ExPEC): ECUMN_3854
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Entry
ECUMN_3854 CDS
T00831
Symbol
mrcA
Name
(GenBank) fused penicillin-binding protein 1a: murein transglycosylase; murein transpeptidase
KO
K05366
penicillin-binding protein 1A [EC:
2.4.99.28
3.4.16.4
]
Organism
eum
Escherichia coli O17:K52:H18 UMN026 (ExPEC)
Pathway
eum00550
Peptidoglycan biosynthesis
eum01100
Metabolic pathways
eum01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
eum00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECUMN_3854 (mrcA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
ECUMN_3854 (mrcA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
eum01003
]
ECUMN_3854 (mrcA)
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
eum01011
]
ECUMN_3854 (mrcA)
Enzymes [BR:
eum01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.99 Transferring other glycosyl groups
2.4.99.28 peptidoglycan glycosyltransferase
ECUMN_3854 (mrcA)
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
ECUMN_3854 (mrcA)
Glycosyltransferases [BR:
eum01003
]
Polysaccharide
Bacterial polysaccharide (excluding LPS)
ECUMN_3854 (mrcA)
Peptidoglycan biosynthesis and degradation proteins [BR:
eum01011
]
Peptidoglycan biosynthesis and degradation
Glycosyltransferase/DD-Transpeptidase (Class A PBP)
ECUMN_3854 (mrcA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transgly
PCB_OB
Transpeptidase
DUF3502
Motif
Other DBs
NCBI-ProteinID:
CAR15000
UniProt:
B7NE00
LinkDB
All DBs
Position
3948686..3951238
Genome browser
AA seq
850 aa
AA seq
DB search
MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQ
YGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGAST
ITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAA
QVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF
DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQ
QAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQ
EATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTDVLQTGQQIWVRQVGDAWWLA
QVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL
TLASMLNDVPISRWDAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDY
AAEYLQRFGFPAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQG
GVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQA
LVAKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTT
NSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAY
MKAVLEGVPEQPLTPPPGIVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTI
IDNGEAQELF
NT seq
2553 nt
NT seq
+upstream
nt +downstream
nt
gtgaagttcgtaaagtattttttgatccttgcagtctgttgcattctgctgggagcaggc
tcgatttatggcctataccgctacatcgagccacaactgccggatgtggcgacattaaaa
gatgttcgcctgcaaattccgatgcagatttacagcgccgatggcgagctgattgctcaa
tacggtgagaaacgtcgtattccggttacgttggatcaaatcccgccggagatggtgaaa
gcctttatcgcgacggaagacagccgcttctacgagcatcacggcgttgacccggtgggg
atcttccgtgcggcaagcgtggcgctgttctccggtcacgcgtcacaaggggcgagtacc
attacccagcagctggcgagaaacttcttcctcagtccagaacgcacgctgatgcgtaag
attaaggaagtcttcctcgcgattcgcattgaacagttgctgacgaaagacgagatcctc
gagctttatctgaacaagatttacctcggttaccgcgcctatggtgtcggtgctgcggca
caagtctatttcggtaaaacggtcgaccaactgacgctgaacgaaatggcggtgatagcc
gggctgccgaaagcgccttccaccttcaacccgctctactcaatggatcgtgccgtcgcg
cggcgtaacgtcgtgctgtcgcggatgctggatgaagggtatatcacccaacaacagttc
gatcagacacgcactgaggcgattaacgctaactatcacgcgccggagattgctttctct
gcgccgtacctgagcgaaatggtgcgccaggagatgtataaccgttatggcgaaagtgcc
tatgaagacggttatcgcatttacaccaccatcacccgcaaagtacagcaggccgcacag
caggcagtacgtaataacgtgctggactacgacatgcgccacggctatcgcggcccggca
aatgtgctgtggaaagtgggcgaatcggcgtgggacaacaacaaaattaccgatacgctg
aaggcgctgccgacctatggtccgctgctgcctgccgcagtcaccagcgccaatcctcag
gaagcgacggcgatgctggcggacgggtcgaccgtcgcattgagtatggaaggcgttcgc
tgggcgcgtccttaccgttcggatactcagcagggaccgacgccgcgtaaagtgaccgat
gttctgcaaacgggtcagcaaatctgggttcgtcaggttggcgatgcatggtggctggca
caagtgccggaagtgaactcggcattggtgtcgatcaatccgcaaaacggtgccgttatg
gcgctggtcggtggctttgatttcaatcagagcaagtttaaccgcgccacccaggcactg
cgtcaggtaggttccaacatcaaaccgttcctctacaccgcggcgatggataaaggtctg
acgctggcaagtatgttgaacgatgtgccaatttcccgctgggatgcaggtgccggttct
gactggcagccgaagaactcaccaccgcagtatgccggcccaattcgcttacgtcaggga
ctgggccagtcgaaaaacgtggtgatggtacgcgcaatgcgggcgatgggcgtcgactac
gctgcagaatatctgcaacgcttcggcttcccggcacaaaacattgtccacaccgaatcg
ctggcgctgggttcagcgtccttcaccccaatgcaggtggcgcgcggctacgcggtcatg
gcgaacggcggcttcctggtggacccgtggtttatcagcaaaattgaaaacgatcagggc
ggcgtgattttcgaagcgaaaccgaaagtagcctgcccggaatgcgatattccggtgatt
tacggtgatacgcagaaatcgaacgtgctggaaaataacgatgttgaagatgtcgctatc
tcccgcgagcagcagaatgtttctgtgccaatgccgcagctggagcaggcaaatcaggcg
ttagtggcgaagactggcgcacaggagtacgcgccgcacgtcatcaacactccgctggca
ttcctgattaagagtgctttgaacaccaatatctttggtgagccaggctggcagggtact
ggctggcgtgcaggtcgtgatttgcagcgtcgcgatatcggcgggaaaaccggtaccact
aacagttcgaaagatgcgtggttttcgggttacggtccgggcgttgtgacctcggtctgg
attggctttgatgatcaccgtcgtaatctcggtcatacaacggcttccggagcgattaaa
gatcagatctcaggttacgaaggcggtgccaagagtgcccagcctgcatgggacgcttat
atgaaagccgttcttgaaggtgtgccggagcagccgctgacgccgccgccgggtattgtg
acggtgaatatcgatcgcagcaccgggcagttagctaatggtggcaacagccgcgaagag
tatttcatcgaaggtacgcagccgacacaacaggcggtgcacgaggtgggaacgaccatt
atcgataatggcgaggcacaggaattgttctga
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