Felis catus (domestic cat): 100499544
Help
Entry
100499544 CDS
T02385
Symbol
AKT2
Name
(RefSeq) RAC-beta serine/threonine-protein kinase isoform X4
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca01522
Endocrine resistance
fca01524
Platinum drug resistance
fca04010
MAPK signaling pathway
fca04012
ErbB signaling pathway
fca04014
Ras signaling pathway
fca04015
Rap1 signaling pathway
fca04022
cGMP-PKG signaling pathway
fca04024
cAMP signaling pathway
fca04062
Chemokine signaling pathway
fca04066
HIF-1 signaling pathway
fca04068
FoxO signaling pathway
fca04071
Sphingolipid signaling pathway
fca04072
Phospholipase D signaling pathway
fca04140
Autophagy - animal
fca04150
mTOR signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04152
AMPK signaling pathway
fca04210
Apoptosis
fca04211
Longevity regulating pathway
fca04213
Longevity regulating pathway - multiple species
fca04218
Cellular senescence
fca04261
Adrenergic signaling in cardiomyocytes
fca04370
VEGF signaling pathway
fca04371
Apelin signaling pathway
fca04380
Osteoclast differentiation
fca04510
Focal adhesion
fca04550
Signaling pathways regulating pluripotency of stem cells
fca04611
Platelet activation
fca04613
Neutrophil extracellular trap formation
fca04620
Toll-like receptor signaling pathway
fca04625
C-type lectin receptor signaling pathway
fca04630
JAK-STAT signaling pathway
fca04660
T cell receptor signaling pathway
fca04662
B cell receptor signaling pathway
fca04664
Fc epsilon RI signaling pathway
fca04666
Fc gamma R-mediated phagocytosis
fca04668
TNF signaling pathway
fca04722
Neurotrophin signaling pathway
fca04725
Cholinergic synapse
fca04728
Dopaminergic synapse
fca04810
Regulation of actin cytoskeleton
fca04910
Insulin signaling pathway
fca04914
Progesterone-mediated oocyte maturation
fca04915
Estrogen signaling pathway
fca04917
Prolactin signaling pathway
fca04919
Thyroid hormone signaling pathway
fca04920
Adipocytokine signaling pathway
fca04922
Glucagon signaling pathway
fca04923
Regulation of lipolysis in adipocytes
fca04926
Relaxin signaling pathway
fca04929
GnRH secretion
fca04931
Insulin resistance
fca04932
Non-alcoholic fatty liver disease
fca04933
AGE-RAGE signaling pathway in diabetic complications
fca04935
Growth hormone synthesis, secretion and action
fca04936
Alcoholic liver disease
fca04973
Carbohydrate digestion and absorption
fca05010
Alzheimer disease
fca05017
Spinocerebellar ataxia
fca05132
Salmonella infection
fca05135
Yersinia infection
fca05142
Chagas disease
fca05145
Toxoplasmosis
fca05152
Tuberculosis
fca05160
Hepatitis C
fca05161
Hepatitis B
fca05162
Measles
fca05163
Human cytomegalovirus infection
fca05164
Influenza A
fca05165
Human papillomavirus infection
fca05166
Human T-cell leukemia virus 1 infection
fca05167
Kaposi sarcoma-associated herpesvirus infection
fca05168
Herpes simplex virus 1 infection
fca05169
Epstein-Barr virus infection
fca05170
Human immunodeficiency virus 1 infection
fca05200
Pathways in cancer
fca05205
Proteoglycans in cancer
fca05207
Chemical carcinogenesis - receptor activation
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05210
Colorectal cancer
fca05211
Renal cell carcinoma
fca05212
Pancreatic cancer
fca05213
Endometrial cancer
fca05214
Glioma
fca05215
Prostate cancer
fca05218
Melanoma
fca05220
Chronic myeloid leukemia
fca05221
Acute myeloid leukemia
fca05222
Small cell lung cancer
fca05223
Non-small cell lung cancer
fca05224
Breast cancer
fca05225
Hepatocellular carcinoma
fca05226
Gastric cancer
fca05230
Central carbon metabolism in cancer
fca05231
Choline metabolism in cancer
fca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
fca05415
Diabetic cardiomyopathy
fca05417
Lipid and atherosclerosis
fca05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100499544 (AKT2)
04012 ErbB signaling pathway
100499544 (AKT2)
04014 Ras signaling pathway
100499544 (AKT2)
04015 Rap1 signaling pathway
100499544 (AKT2)
04370 VEGF signaling pathway
100499544 (AKT2)
04371 Apelin signaling pathway
100499544 (AKT2)
04630 JAK-STAT signaling pathway
100499544 (AKT2)
04668 TNF signaling pathway
100499544 (AKT2)
04066 HIF-1 signaling pathway
100499544 (AKT2)
04068 FoxO signaling pathway
100499544 (AKT2)
04072 Phospholipase D signaling pathway
100499544 (AKT2)
04071 Sphingolipid signaling pathway
100499544 (AKT2)
04024 cAMP signaling pathway
100499544 (AKT2)
04022 cGMP-PKG signaling pathway
100499544 (AKT2)
04151 PI3K-Akt signaling pathway
100499544 (AKT2)
04152 AMPK signaling pathway
100499544 (AKT2)
04150 mTOR signaling pathway
100499544 (AKT2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100499544 (AKT2)
09143 Cell growth and death
04210 Apoptosis
100499544 (AKT2)
04218 Cellular senescence
100499544 (AKT2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100499544 (AKT2)
04550 Signaling pathways regulating pluripotency of stem cells
100499544 (AKT2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100499544 (AKT2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100499544 (AKT2)
04613 Neutrophil extracellular trap formation
100499544 (AKT2)
04620 Toll-like receptor signaling pathway
100499544 (AKT2)
04625 C-type lectin receptor signaling pathway
100499544 (AKT2)
04660 T cell receptor signaling pathway
100499544 (AKT2)
04662 B cell receptor signaling pathway
100499544 (AKT2)
04664 Fc epsilon RI signaling pathway
100499544 (AKT2)
04666 Fc gamma R-mediated phagocytosis
100499544 (AKT2)
04062 Chemokine signaling pathway
100499544 (AKT2)
09152 Endocrine system
04910 Insulin signaling pathway
100499544 (AKT2)
04922 Glucagon signaling pathway
100499544 (AKT2)
04923 Regulation of lipolysis in adipocytes
100499544 (AKT2)
04920 Adipocytokine signaling pathway
100499544 (AKT2)
04929 GnRH secretion
100499544 (AKT2)
04915 Estrogen signaling pathway
100499544 (AKT2)
04914 Progesterone-mediated oocyte maturation
100499544 (AKT2)
04917 Prolactin signaling pathway
100499544 (AKT2)
04926 Relaxin signaling pathway
100499544 (AKT2)
04935 Growth hormone synthesis, secretion and action
100499544 (AKT2)
04919 Thyroid hormone signaling pathway
100499544 (AKT2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100499544 (AKT2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100499544 (AKT2)
09156 Nervous system
04725 Cholinergic synapse
100499544 (AKT2)
04728 Dopaminergic synapse
100499544 (AKT2)
04722 Neurotrophin signaling pathway
100499544 (AKT2)
09158 Development and regeneration
04380 Osteoclast differentiation
100499544 (AKT2)
09149 Aging
04211 Longevity regulating pathway
100499544 (AKT2)
04213 Longevity regulating pathway - multiple species
100499544 (AKT2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100499544 (AKT2)
05205 Proteoglycans in cancer
100499544 (AKT2)
05207 Chemical carcinogenesis - receptor activation
100499544 (AKT2)
05208 Chemical carcinogenesis - reactive oxygen species
100499544 (AKT2)
05230 Central carbon metabolism in cancer
100499544 (AKT2)
05231 Choline metabolism in cancer
100499544 (AKT2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100499544 (AKT2)
09162 Cancer: specific types
05210 Colorectal cancer
100499544 (AKT2)
05212 Pancreatic cancer
100499544 (AKT2)
05225 Hepatocellular carcinoma
100499544 (AKT2)
05226 Gastric cancer
100499544 (AKT2)
05214 Glioma
100499544 (AKT2)
05221 Acute myeloid leukemia
100499544 (AKT2)
05220 Chronic myeloid leukemia
100499544 (AKT2)
05218 Melanoma
100499544 (AKT2)
05211 Renal cell carcinoma
100499544 (AKT2)
05215 Prostate cancer
100499544 (AKT2)
05213 Endometrial cancer
100499544 (AKT2)
05224 Breast cancer
100499544 (AKT2)
05222 Small cell lung cancer
100499544 (AKT2)
05223 Non-small cell lung cancer
100499544 (AKT2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100499544 (AKT2)
05170 Human immunodeficiency virus 1 infection
100499544 (AKT2)
05161 Hepatitis B
100499544 (AKT2)
05160 Hepatitis C
100499544 (AKT2)
05164 Influenza A
100499544 (AKT2)
05162 Measles
100499544 (AKT2)
05168 Herpes simplex virus 1 infection
100499544 (AKT2)
05163 Human cytomegalovirus infection
100499544 (AKT2)
05167 Kaposi sarcoma-associated herpesvirus infection
100499544 (AKT2)
05169 Epstein-Barr virus infection
100499544 (AKT2)
05165 Human papillomavirus infection
100499544 (AKT2)
09171 Infectious disease: bacterial
05132 Salmonella infection
100499544 (AKT2)
05135 Yersinia infection
100499544 (AKT2)
05152 Tuberculosis
100499544 (AKT2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100499544 (AKT2)
05142 Chagas disease
100499544 (AKT2)
09164 Neurodegenerative disease
05010 Alzheimer disease
100499544 (AKT2)
05017 Spinocerebellar ataxia
100499544 (AKT2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100499544 (AKT2)
05418 Fluid shear stress and atherosclerosis
100499544 (AKT2)
05415 Diabetic cardiomyopathy
100499544 (AKT2)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
100499544 (AKT2)
04932 Non-alcoholic fatty liver disease
100499544 (AKT2)
04931 Insulin resistance
100499544 (AKT2)
04933 AGE-RAGE signaling pathway in diabetic complications
100499544 (AKT2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100499544 (AKT2)
01524 Platinum drug resistance
100499544 (AKT2)
01522 Endocrine resistance
100499544 (AKT2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
100499544 (AKT2)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100499544 (AKT2)
Protein kinases [BR:
fca01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
100499544 (AKT2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_20
PH_11
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
100499544
NCBI-ProteinID:
XP_023101825
LinkDB
All DBs
Position
E2:14258501..14310349
Genome browser
AA seq
481 aa
AA seq
DB search
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPDAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQMVANSLKQRGPGEDPM
DYKCGSPSDPSAAEEMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKASGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFH
LSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAREVMEHRFFLSVNWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaatgaggtgtctgtcatcaaagaaggctggctccacaagcgtggtgaatacatcaag
acctggaggccccggtacttcctgctgaagagtgacggctccttcattggatacaaggag
cggcctgatgccccagaccagaccctgcccccgctaaacaacttctctgtcgcagagtgc
cagctgatgaagactgagagaccacggcccaacaccttcgtcatacgctgcctacagtgg
accactgtcatcgagaggaccttccacgtagactctccagacgagagggaggagtggatg
cgggccattcagatggttgccaacagccttaagcagcggggcccaggtgaggaccccatg
gactataagtgtggctcccccagtgacccttctgcggccgaggagatggaagtggcagtt
agcaaggctcgggccaaggtgaccatgaatgacttcgactatctcaaacttctgggcaag
ggcacctttggcaaagtgattctagtgcgggagaaagccagcggccgctactacgccatg
aagatcctgcggaaggaagttatcattgccaaggatgaagttgcccacacggtcaccgag
agccgggtccttcagaacaccaggcacccattcctcactgcactgaagtatgccttccag
acccacgaccgcctgtgcttcgtgatggaatacgccaacggtggtgagctgtttttccac
ctgtcccgggaacgagtcttcacggaggagcgagcccgcttctatggtgcagagatcgtc
tctgcccttgagtatttgcattcgcgggacgtggtgtaccgcgacatcaagctggaaaac
ctcatgctggacaaagatggccacatcaagatcactgacttcggactgtgcaaagagggc
atcagtgacggggctaccatgaaaaccttctgtgggacgcccgagtacctggcacccgag
gtgctggaggacaacgactacggccgcgcggtggactggtgggggctgggcgtggtcatg
tacgagatgatgtgcggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag
ctcatcctcatggaggagatccgtttcccacgcacactgagccctgaggccaagtccctg
cttgctgggctgcttaagaaggaccccaagcagaggctcggcggggggcccagcgatgcc
agggaggtcatggagcacaggttcttcctcagcgtcaactggcaggacgtggtgcagaag
aagctcctgccacccttcaaacctcaggtcacctctgaggttgacacaaggtactttgac
gacgagttcaccgcccagtccattacaatcacgcccccggaccgctatgacagcctgggc
tccctcgaactggaccagcggacccacttcccccagttctcctactcagccagcatccgc
gagtga
Felis catus (domestic cat): 101087931
Help
Entry
101087931 CDS
T02385
Symbol
AKT1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca01522
Endocrine resistance
fca01524
Platinum drug resistance
fca04010
MAPK signaling pathway
fca04012
ErbB signaling pathway
fca04014
Ras signaling pathway
fca04015
Rap1 signaling pathway
fca04022
cGMP-PKG signaling pathway
fca04024
cAMP signaling pathway
fca04062
Chemokine signaling pathway
fca04066
HIF-1 signaling pathway
fca04068
FoxO signaling pathway
fca04071
Sphingolipid signaling pathway
fca04072
Phospholipase D signaling pathway
fca04140
Autophagy - animal
fca04150
mTOR signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04152
AMPK signaling pathway
fca04210
Apoptosis
fca04211
Longevity regulating pathway
fca04213
Longevity regulating pathway - multiple species
fca04218
Cellular senescence
fca04261
Adrenergic signaling in cardiomyocytes
fca04370
VEGF signaling pathway
fca04371
Apelin signaling pathway
fca04380
Osteoclast differentiation
fca04510
Focal adhesion
fca04550
Signaling pathways regulating pluripotency of stem cells
fca04611
Platelet activation
fca04613
Neutrophil extracellular trap formation
fca04620
Toll-like receptor signaling pathway
fca04625
C-type lectin receptor signaling pathway
fca04630
JAK-STAT signaling pathway
fca04660
T cell receptor signaling pathway
fca04662
B cell receptor signaling pathway
fca04664
Fc epsilon RI signaling pathway
fca04666
Fc gamma R-mediated phagocytosis
fca04668
TNF signaling pathway
fca04722
Neurotrophin signaling pathway
fca04725
Cholinergic synapse
fca04728
Dopaminergic synapse
fca04810
Regulation of actin cytoskeleton
fca04910
Insulin signaling pathway
fca04914
Progesterone-mediated oocyte maturation
fca04915
Estrogen signaling pathway
fca04917
Prolactin signaling pathway
fca04919
Thyroid hormone signaling pathway
fca04920
Adipocytokine signaling pathway
fca04922
Glucagon signaling pathway
fca04923
Regulation of lipolysis in adipocytes
fca04926
Relaxin signaling pathway
fca04929
GnRH secretion
fca04931
Insulin resistance
fca04932
Non-alcoholic fatty liver disease
fca04933
AGE-RAGE signaling pathway in diabetic complications
fca04935
Growth hormone synthesis, secretion and action
fca04936
Alcoholic liver disease
fca04973
Carbohydrate digestion and absorption
fca05010
Alzheimer disease
fca05017
Spinocerebellar ataxia
fca05132
Salmonella infection
fca05135
Yersinia infection
fca05142
Chagas disease
fca05145
Toxoplasmosis
fca05152
Tuberculosis
fca05160
Hepatitis C
fca05161
Hepatitis B
fca05162
Measles
fca05163
Human cytomegalovirus infection
fca05164
Influenza A
fca05165
Human papillomavirus infection
fca05166
Human T-cell leukemia virus 1 infection
fca05167
Kaposi sarcoma-associated herpesvirus infection
fca05168
Herpes simplex virus 1 infection
fca05169
Epstein-Barr virus infection
fca05170
Human immunodeficiency virus 1 infection
fca05200
Pathways in cancer
fca05205
Proteoglycans in cancer
fca05207
Chemical carcinogenesis - receptor activation
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05210
Colorectal cancer
fca05211
Renal cell carcinoma
fca05212
Pancreatic cancer
fca05213
Endometrial cancer
fca05214
Glioma
fca05215
Prostate cancer
fca05218
Melanoma
fca05220
Chronic myeloid leukemia
fca05221
Acute myeloid leukemia
fca05222
Small cell lung cancer
fca05223
Non-small cell lung cancer
fca05224
Breast cancer
fca05225
Hepatocellular carcinoma
fca05226
Gastric cancer
fca05230
Central carbon metabolism in cancer
fca05231
Choline metabolism in cancer
fca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
fca05415
Diabetic cardiomyopathy
fca05417
Lipid and atherosclerosis
fca05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101087931 (AKT1)
04012 ErbB signaling pathway
101087931 (AKT1)
04014 Ras signaling pathway
101087931 (AKT1)
04015 Rap1 signaling pathway
101087931 (AKT1)
04370 VEGF signaling pathway
101087931 (AKT1)
04371 Apelin signaling pathway
101087931 (AKT1)
04630 JAK-STAT signaling pathway
101087931 (AKT1)
04668 TNF signaling pathway
101087931 (AKT1)
04066 HIF-1 signaling pathway
101087931 (AKT1)
04068 FoxO signaling pathway
101087931 (AKT1)
04072 Phospholipase D signaling pathway
101087931 (AKT1)
04071 Sphingolipid signaling pathway
101087931 (AKT1)
04024 cAMP signaling pathway
101087931 (AKT1)
04022 cGMP-PKG signaling pathway
101087931 (AKT1)
04151 PI3K-Akt signaling pathway
101087931 (AKT1)
04152 AMPK signaling pathway
101087931 (AKT1)
04150 mTOR signaling pathway
101087931 (AKT1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101087931 (AKT1)
09143 Cell growth and death
04210 Apoptosis
101087931 (AKT1)
04218 Cellular senescence
101087931 (AKT1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101087931 (AKT1)
04550 Signaling pathways regulating pluripotency of stem cells
101087931 (AKT1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101087931 (AKT1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101087931 (AKT1)
04613 Neutrophil extracellular trap formation
101087931 (AKT1)
04620 Toll-like receptor signaling pathway
101087931 (AKT1)
04625 C-type lectin receptor signaling pathway
101087931 (AKT1)
04660 T cell receptor signaling pathway
101087931 (AKT1)
04662 B cell receptor signaling pathway
101087931 (AKT1)
04664 Fc epsilon RI signaling pathway
101087931 (AKT1)
04666 Fc gamma R-mediated phagocytosis
101087931 (AKT1)
04062 Chemokine signaling pathway
101087931 (AKT1)
09152 Endocrine system
04910 Insulin signaling pathway
101087931 (AKT1)
04922 Glucagon signaling pathway
101087931 (AKT1)
04923 Regulation of lipolysis in adipocytes
101087931 (AKT1)
04920 Adipocytokine signaling pathway
101087931 (AKT1)
04929 GnRH secretion
101087931 (AKT1)
04915 Estrogen signaling pathway
101087931 (AKT1)
04914 Progesterone-mediated oocyte maturation
101087931 (AKT1)
04917 Prolactin signaling pathway
101087931 (AKT1)
04926 Relaxin signaling pathway
101087931 (AKT1)
04935 Growth hormone synthesis, secretion and action
101087931 (AKT1)
04919 Thyroid hormone signaling pathway
101087931 (AKT1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101087931 (AKT1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
101087931 (AKT1)
09156 Nervous system
04725 Cholinergic synapse
101087931 (AKT1)
04728 Dopaminergic synapse
101087931 (AKT1)
04722 Neurotrophin signaling pathway
101087931 (AKT1)
09158 Development and regeneration
04380 Osteoclast differentiation
101087931 (AKT1)
09149 Aging
04211 Longevity regulating pathway
101087931 (AKT1)
04213 Longevity regulating pathway - multiple species
101087931 (AKT1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101087931 (AKT1)
05205 Proteoglycans in cancer
101087931 (AKT1)
05207 Chemical carcinogenesis - receptor activation
101087931 (AKT1)
05208 Chemical carcinogenesis - reactive oxygen species
101087931 (AKT1)
05230 Central carbon metabolism in cancer
101087931 (AKT1)
05231 Choline metabolism in cancer
101087931 (AKT1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101087931 (AKT1)
09162 Cancer: specific types
05210 Colorectal cancer
101087931 (AKT1)
05212 Pancreatic cancer
101087931 (AKT1)
05225 Hepatocellular carcinoma
101087931 (AKT1)
05226 Gastric cancer
101087931 (AKT1)
05214 Glioma
101087931 (AKT1)
05221 Acute myeloid leukemia
101087931 (AKT1)
05220 Chronic myeloid leukemia
101087931 (AKT1)
05218 Melanoma
101087931 (AKT1)
05211 Renal cell carcinoma
101087931 (AKT1)
05215 Prostate cancer
101087931 (AKT1)
05213 Endometrial cancer
101087931 (AKT1)
05224 Breast cancer
101087931 (AKT1)
05222 Small cell lung cancer
101087931 (AKT1)
05223 Non-small cell lung cancer
101087931 (AKT1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101087931 (AKT1)
05170 Human immunodeficiency virus 1 infection
101087931 (AKT1)
05161 Hepatitis B
101087931 (AKT1)
05160 Hepatitis C
101087931 (AKT1)
05164 Influenza A
101087931 (AKT1)
05162 Measles
101087931 (AKT1)
05168 Herpes simplex virus 1 infection
101087931 (AKT1)
05163 Human cytomegalovirus infection
101087931 (AKT1)
05167 Kaposi sarcoma-associated herpesvirus infection
101087931 (AKT1)
05169 Epstein-Barr virus infection
101087931 (AKT1)
05165 Human papillomavirus infection
101087931 (AKT1)
09171 Infectious disease: bacterial
05132 Salmonella infection
101087931 (AKT1)
05135 Yersinia infection
101087931 (AKT1)
05152 Tuberculosis
101087931 (AKT1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101087931 (AKT1)
05142 Chagas disease
101087931 (AKT1)
09164 Neurodegenerative disease
05010 Alzheimer disease
101087931 (AKT1)
05017 Spinocerebellar ataxia
101087931 (AKT1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101087931 (AKT1)
05418 Fluid shear stress and atherosclerosis
101087931 (AKT1)
05415 Diabetic cardiomyopathy
101087931 (AKT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101087931 (AKT1)
04932 Non-alcoholic fatty liver disease
101087931 (AKT1)
04931 Insulin resistance
101087931 (AKT1)
04933 AGE-RAGE signaling pathway in diabetic complications
101087931 (AKT1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101087931 (AKT1)
01524 Platinum drug resistance
101087931 (AKT1)
01522 Endocrine resistance
101087931 (AKT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101087931 (AKT1)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101087931 (AKT1)
Protein kinases [BR:
fca01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
101087931 (AKT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_20
PH_11
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
101087931
NCBI-ProteinID:
NP_001309364
UniProt:
A0A143RHU3
LinkDB
All DBs
Position
B3:complement(146095795..146116673)
Genome browser
AA seq
480 aa
AA seq
DB search
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEEMMDF
RSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFPEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMLCGRLPFYNQDHEKLFEL
ILMEELRFPRTLSPEAKSLLSGLLKKDPKQRLGGGAEDAKEIMQHRFFASIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQGDSVEGEDSERRPHFPQFSYSASGTA
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgaacgacgtggccatcgtgaaggagggttggctgcacaagagaggggaatacatcaag
acctggaggccccggtacttcctcctcaagaacgacggcaccttcatcggctacaaggag
cggccacaggacgtggagcagagagagtccccgctcaacaacttctctgtggcgcagtgt
cagctgatgaagacggagcggcccaggcccaacaccttcatcatccgctgcctgcagtgg
accacggtcatcgagcgcaccttccacgtggagacccccgaggagcgggaggagtggacc
accgccatccagacagtggccgacgggctcaagaggcaggaggaggaaatgatggacttc
cggtcgggctcgcccagcgacaactcgggggccgaggagatggaggtgtccctggccaag
cccaagcaccgcgtgaccatgaacgagtttgagtacctgaagctgctggggaaaggcacg
ttcgggaaggtaatcctggtgaaggagaaggccacgggccgctactacgccatgaagatc
ctcaagaaggaggtcatcgtggccaaggatgaggtggcccacacgctcacagagaaccgc
gttctccagaactctcggcaccctttcctgacggccctgaagtactccttccagacccac
gaccgtctctgcttcgtcatggagtatgccaacgggggcgagctcttcttccacttgtcc
cgggagcgggtcttccccgaggaccgtgcgcgcttctacggcgccgagatcgtgtccgcg
ctggactacctgcactccgagaagaacgtggtctaccgcgacctcaagctggagaacctc
atgctggacaaggacgggcacatcaagatcaccgacttcggcctgtgcaaggagggcatc
aaggacggtgccaccatgaagaccttctgtgggacgcccgagtacctggcccccgaggtg
ctggaggacaacgactacggccgcgcggtcgactggtgggggctgggcgtggtcatgtac
gagatgctgtgcggccgcctgcccttctacaaccaggaccacgagaagctcttcgagctc
atcctcatggaggagctccgcttcccgcgcacgctcagccccgaggccaagtccctgctg
tcggggctgctcaagaaggaccctaagcagaggctgggagggggcgccgaggacgccaag
gagatcatgcagcaccgctttttcgccagcatcgtgtggcaggacgtgtacgagaagaag
ctcagtccgcccttcaagccccaggtcacctcagagacggacaccaggtattttgatgag
gagttcacggcccagatgatcaccatcacgccccccgaccaaggcgacagcgtggagggc
gaggacagcgagcggaggccccacttcccacagttctcctactccgccagcggcacggcc
tga
Felis catus (domestic cat): 101092818
Help
Entry
101092818 CDS
T02385
Symbol
AKT3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X4
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01521
EGFR tyrosine kinase inhibitor resistance
fca01522
Endocrine resistance
fca01524
Platinum drug resistance
fca04010
MAPK signaling pathway
fca04012
ErbB signaling pathway
fca04014
Ras signaling pathway
fca04015
Rap1 signaling pathway
fca04022
cGMP-PKG signaling pathway
fca04024
cAMP signaling pathway
fca04062
Chemokine signaling pathway
fca04066
HIF-1 signaling pathway
fca04068
FoxO signaling pathway
fca04071
Sphingolipid signaling pathway
fca04072
Phospholipase D signaling pathway
fca04140
Autophagy - animal
fca04150
mTOR signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04152
AMPK signaling pathway
fca04210
Apoptosis
fca04211
Longevity regulating pathway
fca04213
Longevity regulating pathway - multiple species
fca04218
Cellular senescence
fca04261
Adrenergic signaling in cardiomyocytes
fca04370
VEGF signaling pathway
fca04371
Apelin signaling pathway
fca04380
Osteoclast differentiation
fca04510
Focal adhesion
fca04550
Signaling pathways regulating pluripotency of stem cells
fca04611
Platelet activation
fca04613
Neutrophil extracellular trap formation
fca04620
Toll-like receptor signaling pathway
fca04625
C-type lectin receptor signaling pathway
fca04630
JAK-STAT signaling pathway
fca04660
T cell receptor signaling pathway
fca04662
B cell receptor signaling pathway
fca04664
Fc epsilon RI signaling pathway
fca04666
Fc gamma R-mediated phagocytosis
fca04668
TNF signaling pathway
fca04722
Neurotrophin signaling pathway
fca04725
Cholinergic synapse
fca04728
Dopaminergic synapse
fca04810
Regulation of actin cytoskeleton
fca04910
Insulin signaling pathway
fca04914
Progesterone-mediated oocyte maturation
fca04915
Estrogen signaling pathway
fca04917
Prolactin signaling pathway
fca04919
Thyroid hormone signaling pathway
fca04920
Adipocytokine signaling pathway
fca04922
Glucagon signaling pathway
fca04923
Regulation of lipolysis in adipocytes
fca04926
Relaxin signaling pathway
fca04929
GnRH secretion
fca04931
Insulin resistance
fca04932
Non-alcoholic fatty liver disease
fca04933
AGE-RAGE signaling pathway in diabetic complications
fca04935
Growth hormone synthesis, secretion and action
fca04936
Alcoholic liver disease
fca04973
Carbohydrate digestion and absorption
fca05010
Alzheimer disease
fca05017
Spinocerebellar ataxia
fca05132
Salmonella infection
fca05135
Yersinia infection
fca05142
Chagas disease
fca05145
Toxoplasmosis
fca05152
Tuberculosis
fca05160
Hepatitis C
fca05161
Hepatitis B
fca05162
Measles
fca05163
Human cytomegalovirus infection
fca05164
Influenza A
fca05165
Human papillomavirus infection
fca05166
Human T-cell leukemia virus 1 infection
fca05167
Kaposi sarcoma-associated herpesvirus infection
fca05168
Herpes simplex virus 1 infection
fca05169
Epstein-Barr virus infection
fca05170
Human immunodeficiency virus 1 infection
fca05200
Pathways in cancer
fca05205
Proteoglycans in cancer
fca05207
Chemical carcinogenesis - receptor activation
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05210
Colorectal cancer
fca05211
Renal cell carcinoma
fca05212
Pancreatic cancer
fca05213
Endometrial cancer
fca05214
Glioma
fca05215
Prostate cancer
fca05218
Melanoma
fca05220
Chronic myeloid leukemia
fca05221
Acute myeloid leukemia
fca05222
Small cell lung cancer
fca05223
Non-small cell lung cancer
fca05224
Breast cancer
fca05225
Hepatocellular carcinoma
fca05226
Gastric cancer
fca05230
Central carbon metabolism in cancer
fca05231
Choline metabolism in cancer
fca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
fca05415
Diabetic cardiomyopathy
fca05417
Lipid and atherosclerosis
fca05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101092818 (AKT3)
04012 ErbB signaling pathway
101092818 (AKT3)
04014 Ras signaling pathway
101092818 (AKT3)
04015 Rap1 signaling pathway
101092818 (AKT3)
04370 VEGF signaling pathway
101092818 (AKT3)
04371 Apelin signaling pathway
101092818 (AKT3)
04630 JAK-STAT signaling pathway
101092818 (AKT3)
04668 TNF signaling pathway
101092818 (AKT3)
04066 HIF-1 signaling pathway
101092818 (AKT3)
04068 FoxO signaling pathway
101092818 (AKT3)
04072 Phospholipase D signaling pathway
101092818 (AKT3)
04071 Sphingolipid signaling pathway
101092818 (AKT3)
04024 cAMP signaling pathway
101092818 (AKT3)
04022 cGMP-PKG signaling pathway
101092818 (AKT3)
04151 PI3K-Akt signaling pathway
101092818 (AKT3)
04152 AMPK signaling pathway
101092818 (AKT3)
04150 mTOR signaling pathway
101092818 (AKT3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101092818 (AKT3)
09143 Cell growth and death
04210 Apoptosis
101092818 (AKT3)
04218 Cellular senescence
101092818 (AKT3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101092818 (AKT3)
04550 Signaling pathways regulating pluripotency of stem cells
101092818 (AKT3)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101092818 (AKT3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101092818 (AKT3)
04613 Neutrophil extracellular trap formation
101092818 (AKT3)
04620 Toll-like receptor signaling pathway
101092818 (AKT3)
04625 C-type lectin receptor signaling pathway
101092818 (AKT3)
04660 T cell receptor signaling pathway
101092818 (AKT3)
04662 B cell receptor signaling pathway
101092818 (AKT3)
04664 Fc epsilon RI signaling pathway
101092818 (AKT3)
04666 Fc gamma R-mediated phagocytosis
101092818 (AKT3)
04062 Chemokine signaling pathway
101092818 (AKT3)
09152 Endocrine system
04910 Insulin signaling pathway
101092818 (AKT3)
04922 Glucagon signaling pathway
101092818 (AKT3)
04923 Regulation of lipolysis in adipocytes
101092818 (AKT3)
04920 Adipocytokine signaling pathway
101092818 (AKT3)
04929 GnRH secretion
101092818 (AKT3)
04915 Estrogen signaling pathway
101092818 (AKT3)
04914 Progesterone-mediated oocyte maturation
101092818 (AKT3)
04917 Prolactin signaling pathway
101092818 (AKT3)
04926 Relaxin signaling pathway
101092818 (AKT3)
04935 Growth hormone synthesis, secretion and action
101092818 (AKT3)
04919 Thyroid hormone signaling pathway
101092818 (AKT3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101092818 (AKT3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
101092818 (AKT3)
09156 Nervous system
04725 Cholinergic synapse
101092818 (AKT3)
04728 Dopaminergic synapse
101092818 (AKT3)
04722 Neurotrophin signaling pathway
101092818 (AKT3)
09158 Development and regeneration
04380 Osteoclast differentiation
101092818 (AKT3)
09149 Aging
04211 Longevity regulating pathway
101092818 (AKT3)
04213 Longevity regulating pathway - multiple species
101092818 (AKT3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101092818 (AKT3)
05205 Proteoglycans in cancer
101092818 (AKT3)
05207 Chemical carcinogenesis - receptor activation
101092818 (AKT3)
05208 Chemical carcinogenesis - reactive oxygen species
101092818 (AKT3)
05230 Central carbon metabolism in cancer
101092818 (AKT3)
05231 Choline metabolism in cancer
101092818 (AKT3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101092818 (AKT3)
09162 Cancer: specific types
05210 Colorectal cancer
101092818 (AKT3)
05212 Pancreatic cancer
101092818 (AKT3)
05225 Hepatocellular carcinoma
101092818 (AKT3)
05226 Gastric cancer
101092818 (AKT3)
05214 Glioma
101092818 (AKT3)
05221 Acute myeloid leukemia
101092818 (AKT3)
05220 Chronic myeloid leukemia
101092818 (AKT3)
05218 Melanoma
101092818 (AKT3)
05211 Renal cell carcinoma
101092818 (AKT3)
05215 Prostate cancer
101092818 (AKT3)
05213 Endometrial cancer
101092818 (AKT3)
05224 Breast cancer
101092818 (AKT3)
05222 Small cell lung cancer
101092818 (AKT3)
05223 Non-small cell lung cancer
101092818 (AKT3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101092818 (AKT3)
05170 Human immunodeficiency virus 1 infection
101092818 (AKT3)
05161 Hepatitis B
101092818 (AKT3)
05160 Hepatitis C
101092818 (AKT3)
05164 Influenza A
101092818 (AKT3)
05162 Measles
101092818 (AKT3)
05168 Herpes simplex virus 1 infection
101092818 (AKT3)
05163 Human cytomegalovirus infection
101092818 (AKT3)
05167 Kaposi sarcoma-associated herpesvirus infection
101092818 (AKT3)
05169 Epstein-Barr virus infection
101092818 (AKT3)
05165 Human papillomavirus infection
101092818 (AKT3)
09171 Infectious disease: bacterial
05132 Salmonella infection
101092818 (AKT3)
05135 Yersinia infection
101092818 (AKT3)
05152 Tuberculosis
101092818 (AKT3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
101092818 (AKT3)
05142 Chagas disease
101092818 (AKT3)
09164 Neurodegenerative disease
05010 Alzheimer disease
101092818 (AKT3)
05017 Spinocerebellar ataxia
101092818 (AKT3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101092818 (AKT3)
05418 Fluid shear stress and atherosclerosis
101092818 (AKT3)
05415 Diabetic cardiomyopathy
101092818 (AKT3)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101092818 (AKT3)
04932 Non-alcoholic fatty liver disease
101092818 (AKT3)
04931 Insulin resistance
101092818 (AKT3)
04933 AGE-RAGE signaling pathway in diabetic complications
101092818 (AKT3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101092818 (AKT3)
01524 Platinum drug resistance
101092818 (AKT3)
01522 Endocrine resistance
101092818 (AKT3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101092818 (AKT3)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101092818 (AKT3)
Protein kinases [BR:
fca01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
101092818 (AKT3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
PH
FTA2
ABC1
Motif
Other DBs
NCBI-GeneID:
101092818
NCBI-ProteinID:
XP_011289140
UniProt:
A0A5F5XEI1
LinkDB
All DBs
Position
F1:6020622..6327453
Genome browser
AA seq
451 aa
AA seq
DB search
MTPTLVLHSLSRETRLCDLWRVPSSGIFSECQLMKTERPKPNTFIIRCLQWTTVIERTFH
VDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDNIGEEEMDASTTHHKRKTMNDF
DYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTRHPFL
TSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIV
YRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYGRAVD
WWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKDPNKR
LGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITP
PEKYDEDGMDGVDSERRPHFPQFSYSASGRE
NT seq
1356 nt
NT seq
+upstream
nt +downstream
nt
atgacccccactttggttctgcattcactgagcagagagacgaggctgtgcgacctgtgg
agagtcccttcttctggaatattctctgaatgccagttaatgaaaacagaacgaccaaag
ccaaacacatttattatcagatgtctccagtggaccactgttatagagagaacatttcat
gtagatactccagaggaaagggaagagtggacagaagctattcaggctgtagcagacaga
cttcagagacaagaagaggagagaatgaattgtagtccaacttcacaaattgataacata
ggggaggaagagatggacgcttccacaacccatcataaaagaaagacaatgaatgatttt
gactatttgaaactactaggtaaaggcacttttggaaaagttattttggttcgagagaag
gcaagtggaaaatactatgctatgaagattctgaagaaagaagttattattgcaaaggat
gaagtggcacacactctcactgagagcagagtgttaaagaacactagacaccccttttta
acatccttgaaatattccttccagacaaaagaccgtttgtgttttgtgatggaatatgtt
aatgggggagagctgtttttccatttgtcgagagagcgggtgttctccgaggaccgcaca
cgtttctatggtgcagaaattgtctctgccttggactatctacattccggaaagattgtg
taccgtgatctcaagttggagaatctgatgctggataaagatggccacataaaaattaca
gattttggactttgcaaagaagggattacagatgcggccaccatgaagacgttctgtgga
acaccagaatatctggcaccagaggtgttagaagacaatgactatggccgagccgtggat
tggtggggactaggggtcgtcatgtatgaaatgatgtgtgggaggttacctttctacaac
caggatcatgagaaactttttgaactaatactaatggaagacattaaatttcctcggaca
ctctcttcagatgcaaaatcattgctttcagggctcttgataaaggatccaaataaacgc
cttggtggaggaccagatgatgcaaaagaaattatgaggcacagtttcttttctggagtt
aactggcaagatgtgtatgataaaaagcttgtacctccttttaagcctcaagtaacatct
gagacagataccagatattttgatgaagaatttacagctcagactattacaataacacca
cctgaaaaatatgacgaggacggcatggatggtgtggacagcgagcggcggccacatttc
cctcagttctcctactctgccagcggccgggaataa
DBGET
integrated database retrieval system