KEGG   Felis catus (domestic cat): 101085388
Entry
101085388         CDS       T02385                                 
Symbol
ERBB3
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3 precursor
  KO
K05084  receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]
Organism
fca  Felis catus (domestic cat)
Pathway
fca01521  EGFR tyrosine kinase inhibitor resistance
fca04010  MAPK signaling pathway
fca04012  ErbB signaling pathway
fca04020  Calcium signaling pathway
fca04151  PI3K-Akt signaling pathway
fca05205  Proteoglycans in cancer
fca05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101085388 (ERBB3)
   04012 ErbB signaling pathway
    101085388 (ERBB3)
   04020 Calcium signaling pathway
    101085388 (ERBB3)
   04151 PI3K-Akt signaling pathway
    101085388 (ERBB3)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    101085388 (ERBB3)
   05205 Proteoglycans in cancer
    101085388 (ERBB3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101085388 (ERBB3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:fca01001]
    101085388 (ERBB3)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101085388 (ERBB3)
Protein kinases [BR:fca01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   101085388 (ERBB3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Furin-like Pkinase Kinase-like DUF4381
Other DBs
NCBI-GeneID: 101085388
NCBI-ProteinID: NP_001306203
Ensembl: ENSFCAG00000014859
UniProt: M3WLH4
LinkDB
Position
B4:84715119..84733137
AA seq 1339 aa
MRANGALQVLGFFLSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLHKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG
KSCPPCHEACKGRCWGPRLEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCFACRLFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNITSLGLRSLKEISAGRIYISANRQLCYHHSLNWTRLLRGPPEE
RLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFAHEAECFSCHPECQPMEGSATCNGSGSDACAQCAHFRDGPHCVSSCPYGVLGAKGPI
YKYPDSQNECRPCHENCTQGCKGPELQDCLGQTPALISKTHLAMGLTVVVGLAVVFLILG
GTFLYLRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVF
GTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQDVTDHMLAIGSLDHAHIVRLLGLCPG
SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
VWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRESGPGIPPGAEPPALTNKELEEVELEPELELDLDLESEED
GLAATLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGEACQESAVCGGSERCPRP
VSLHPLPRGRLASESSEGHVTGSEAELQEKVSMCRSRSRSPRPRGDSAYHSQRHSLLTPV
TPLSPPGLEEEDVNGYVMPDAHLKGTPSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRR
RRRSPPRPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLNPVPIMATAGTTPDEDYEYM
NRRHGGGAPGGDYAAMGACPAAEQGYEEMRAFQGPGHHAPHVHCARLKTLRSLEATDSAF
DNPDYWHSRLFPKANAQRT
NT seq 4020 nt   +upstreamnt  +downstreamnt
atgagggcgaatggggctctgcaggtgctgggcttctttctcagcttggcccggggctcc
gaggtgggcaactcgcaggcagtctgtcccgggactctgaatgggctgagcgtgactggc
gatgccgagaaccagtaccagacgttgcacaagctctacgagaggtgtgaggtggtgatg
gggaaccttgagattgtgctcacaggacacaatgctgatctctccttcctgcagtggatc
cgagaagtgaccggctatgtcctcgtggccatgaatgagttctctacactgccactaccc
aacctccgggtggtgcgggggacccaggtctacgatgggaagtttgccatctttgtcatg
ttgaactataacaccaactctagccatgctctgcgccagctccgctttactcagctcacc
gagattctgtcagggggtgtttatattgagaagaatgataaactttgtcacatggacaca
atcgactggagggacatcgtgagggaccgagatgccgagatagtggtgaaggacaatggc
aagagctgtcccccctgtcatgaggcctgcaaggggcgctgctggggtcctagactggaa
gactgccagacattgaccaagaccatctgtgcccctcagtgtaatggtcactgctttggg
cccaaccccaaccagtgctgccatgatgagtgtgcagggggctgctcaggccctcaggat
acagactgctttgcctgtcgactcttcaatgacagtggggcgtgtgtacgccagtgtcca
cagcctctcgtttacaacaagctaactttccaactggaacccaatccccacaccaagtat
cagtatggtggagtttgtgtagccagctgtccccataactttgtggtagatcaaacatct
tgtgtccgggcctgtcctcctgacaagatggaagtagataaaaatggactcaagatgtgt
gaaccttgtggggggctgtgccctaaagcctgtgaggggacgggctccgggagccgcttc
cagactgtggactctagcaacattgatgggtttgtgaactgcaccaagatcctgggcaac
ctggactttcttatcactggcctcaatggcgacccctggcacaagatccctgccctggac
cctgagaagctcaatgtcttccggacagtacgggagatcacaggttacctgaacatccaa
tcctggcctccccacatgcacaacttcagtgtcttttccaacctgacaaccattgggggc
aggagcctctacaaccggggcttctctttgttgatcatgaagaacttgaatataacatca
ttgggcctccgatctttgaaagaaatcagtgccgggcgtatctacataagcgccaatagg
cagctgtgctaccaccattctctgaactggacccggctgctgcgggggcctccggaagag
agactagacatcaaacataaccggccccgcagagactgtgtggcagagggcaaagtatgt
gatcccctgtgctcctctgggggatgctggggcccaggtcctggtcagtgcctatcctgt
cgaaactacagccgaggcggtgtctgtgtgacccactgcaactttctgaatggggagcct
cgtgagtttgcccatgaggctgaatgcttctcctgtcacccggagtgccaacccatggag
ggtagtgccacgtgcaatggctcgggctctgatgcatgtgctcagtgtgcccattttcga
gatgggcctcactgtgtgagcagctgcccctatggagtccttggtgccaagggccccatc
tacaagtacccagattctcagaatgaatgtcggccctgccatgagaactgcacccagggg
tgtaagggaccagagctacaagactgtttaggccaaacaccagcactgatcagcaaaacc
catctggcaatgggtttaacagtggtagtaggattggcagtggttttcctgatcctggga
ggcacttttctctatttgcgtgggcgccggattcagaataagagggctatgaggcgctac
ttggaacggggtgagagcatagaacctctggatcccagtgagaaggctaacaaagtcttg
gccagaatcttcaaagaaacagagctgaggaagcttaaagtgcttggctcgggcgtcttt
ggaactgtgcacaaaggagtgtggattcctgagggtgaatcaatcaagattccagtctgc
attaaagtcattgaggataagagtggacggcaaagttttcaagatgtgacagaccacatg
ctggccattggcagcctagaccatgcccacattgtacggctgctgggactgtgcccaggg
tcatctctgcagcttgtcactcagtacttgcctctgggctccctgctggaccacgtgaga
caacaccgtggagcactggggccccagctgctgctcaactggggagtacagattgccaag
ggtatgtactaccttgaggagcatggtatggtgcataggaacttggctgcccgaaatgtg
ctactgaagtcacccagtcaggttcaggtggcagattttggggtggcggacctgctgccc
cctgacgataagcagctactacacagtgaggccaagactccaattaagtggatggccctc
gagagtatccattttgggaaatacacacaccagagtgacgtctggagctatggagtgaca
gtttgggagctgatgacctttggggcagagccctatgctgggctacgactggctgaagta
ccagacctgctagagaagggggagcgattggcgcagcctcagatctgtaccattgatgtg
tacatggtcatggtcaagtgttggatgattgatgagaatattcgcccaacctttaaagaa
ctagccaatgagtttaccaggatggcccgagacccaccacggtatctggtcataaagaga
gaaagtgggcctggaataccccctggagcagaaccccctgctctgacaaacaaggaactg
gaggaagtggagctggagccagaacttgagctggacctggacttggaatcagaggaggat
ggcctggcagccacactaggctctgctctcagcctgccagttggaacacttaatcggccc
cgtgggagccagagccttttaagcccatcatctggctatatgcctatgaaccagggtaat
cttggggaggcctgccaggagtctgcagtctgtgggggtagtgagcggtgtccccgtcca
gtctccctgcacccactgccacggggacgcctggcatcagagtcttcagaaggccatgtg
acaggctctgaggctgagctccaggagaaggtgtcaatgtgtaggagccggagccggagc
ccacggccacgtggagacagtgcctaccattcccagcgccacagcctgctcactcctgtc
accccactctccccaccaggattagaggaagaggatgtcaatggatatgtcatgccagat
gcacacctcaaaggtactccctcctcccgggagggcaccctttcttcagtgggcctcagt
tctgtcctgggtactgaagaagaagatgaagatgaggaatatgaatacatgaaccggaga
agaaggcgcagtccgcctcgtccccctaggcctagctctcttgaggagctgggttatgag
tacatggatgtgggatcagacctcagcgcttccctgggcagcacacagagttgcccactc
aaccctgtgccaatcatggccactgctggcacaaccccggatgaggactatgaatatatg
aatcggcgacatggtgggggagctcctgggggagattacgcagctatgggggcctgccca
gcagctgaacaagggtatgaagagatgagagctttccaggggcctggacaccatgccccc
catgtccactgtgcccgcctcaaaactctacgtagtttagaagccactgactccgctttt
gataaccctgattactggcacagcaggcttttccccaaggctaatgctcagagaacataa

KEGG   Felis catus (domestic cat): 101100073
Entry
101100073         CDS       T02385                                 
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4 isoform X2
  KO
K05085  receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
Organism
fca  Felis catus (domestic cat)
Pathway
fca04010  MAPK signaling pathway
fca04012  ErbB signaling pathway
fca04020  Calcium signaling pathway
fca04151  PI3K-Akt signaling pathway
fca05014  Amyotrophic lateral sclerosis
fca05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101100073 (ERBB4)
   04012 ErbB signaling pathway
    101100073 (ERBB4)
   04020 Calcium signaling pathway
    101100073 (ERBB4)
   04151 PI3K-Akt signaling pathway
    101100073 (ERBB4)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101100073 (ERBB4)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101100073 (ERBB4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:fca01001]
    101100073 (ERBB4)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101100073 (ERBB4)
Protein kinases [BR:fca01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   101100073 (ERBB4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like Haspin_kinase Kinase-like APH DUF3951 ABC1
Other DBs
NCBI-GeneID: 101100073
NCBI-ProteinID: XP_003991158
UniProt: A0A337S8Z7
LinkDB
Position
C1:complement(197223232..198363892)
AA seq 1308 aa
MKLATGLWVWVSLLLAAGTVQPNASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAVF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVST
NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
INQRIVIRDNRKAENCTAAGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRSCIESCNLYD
GEFREFENGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGA
NSFIFKYADQDRECHPCHPNCTQGCSGPTSHDCIYYPWTGHSTLPQHARTPLIAAGVIGG
LFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKR
VKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHL
VRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLV
HRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQ
SDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMID
ADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAE
EYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVPVP
YRATTSTIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVPEDSSTQRYSADPTVFAPERS
PRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAED
EYVNEPLYLNTFANALGNAGYLKNNVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQ
EYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq 3927 nt   +upstreamnt  +downstreamnt
atgaagctggcgacaggactgtgggtctgggtgagccttctcctggcggcggggaccgtc
cagcccaacgcttctcagtcagtgtgtgcagggacagagaacaagctgagctctctctct
gacctggagcagcagtatcgagccttgcgcaaatactatgagaactgtgaggtggtcatg
ggcaacctggagataaccagcattgagcacaaccgggacctctcctttctgcggtctatt
cgagaagttacaggctacgtgttagtggcacttaatcagtttcgctacctgcctctggag
aatttacgcattatccgtggaacaaaactttatgaggatcgatatgccttggcagtattt
ttaaactacagaaaagatgggaactttggacttcaagaacttgggctaaagaacttgaca
gaaatccttaatggtggagtctatgtagaccagaacaaatttctttgttacacagacaca
attcattggcaagatattgttcggaatccgtggccttccaacttgactctcgtgtcaaca
aacggtagctcaggatgtggacgttgccataagtcctgtactggccgatgctggggaccc
acagaaaatcattgccagacgttgacaaggacggtgtgtgcagaacagtgtgacggcagg
tgctatggaccctacgtcagtgactgctgtcatagagaatgtgctggaggttgctcagga
ccaaaagacacggactgctttgcctgcatgaatttcaatgacagtggagcgtgtgttact
caatgtccccaaacttttgtctacaatccaaccacctttcagctggaacataacttcaat
gcaaagtatacatatggagcattttgtgtcaagaaatgcccacataactttgtggtggat
tccagttcttgtgtgcgtgcttgccctagttccaagatggaagtagaagaaaatgggatt
aaaatgtgtaaaccttgcactgatatttgcccaaaagcttgtgatggcattggcacagga
tcactgatgtcagctcagaccgtggattccagtaacatcgacaaattcataaactgcacc
aaaatcaatgggaatttgatcttccttgtcactggtattcatggggacccttacaatgca
attgaagccatagacccagagaaactgaatgtctttcggaccgttcgagagataacaggt
ttcttgaacatacagtcatggcctccaaacatgactgacttcagtgttttttctaacctg
gtgaccattggtggaagagtactctacagtggcctctccttgcttatcctcaaacaacag
ggcatcacttctctacaattccagtccctgaaggaaatcagtgcaggaaacatctatatt
actgacaacagcaacctatgttattatcataccattaattggacaacactcttcagcact
atcaaccaaagaatagtgatccgggacaacagaaaagctgaaaactgtactgctgcagga
atggtgtgcaaccatctgtgttcaagtgatggctgctggggacctggcccagaccaatgt
ctgtcctgccgtcgcttcagcagaggaaggagctgcatagagtcttgtaacctctatgat
ggtgaatttcgagagtttgagaatggctccatctgtgtggagtgtgacccccagtgcgag
aagatggaagacggcatcctcacatgccatggaccgggacctgataactgcacaaagtgt
tcccattttaaggatggcccgaactgtgtggaaaaatgtccagatggcttgcagggggca
aacagtttcattttcaagtatgctgatcaggatcgagagtgccatccatgccatccaaac
tgcacccaagggtgtagcggccccactagtcatgactgcatttactatccttggacgggc
cattccactttaccacaacatgctagaactcctctaattgcagctggagtcatcggcggg
ctcttcatcctggtcatcgtgggtctaacatttgcagtttatgttagaaggaagagtatc
aaaaagaaaagagccctgagaagatttctggaaacagagttggtagaacccttaactccc
agtggcacagcacccaatcaagctcaactgcgtattttaaaagaaactgagctcaaaaga
gtgaaagtacttggctcgggagcttttggaacagtgtataaaggtatttgggtacctgaa
ggagaaacagtaaagattcctgtggctattaagattcttaatgaaacaactggtcccaaa
gccaatgtggagttcatggatgaagctttgatcatggcaagtatggaccatccacactta
gtccggttattgggtgtgtgtctgagcccaaccattcaactggttacacagcttatgccc
catggctgcctgttggattatgtccatgaacataaggataacattggatcccagctactg
cttaactggtgtgtccaaatagctaagggaatgatgtacctggaggaaagacggcttgtt
catcgggatttggcagcccgaaatgtcttagtgaaatctccaaaccatgtgaaaatcaca
gattttggactagctaggctcttagaaggagatgaaaaagagtataatgctgatggagga
aagatgccaattaaatggatggctctggagtgtatacactacaggaagtttacccatcag
agtgatgtttggagttatggagttaccatatgggaactgatgacctttggaggaaaaccc
tatgatggaattccaaccagagaaatcccggatttattagagaaaggagaacgtttgccc
cagcctcctatctgcactattgacgtttacatggtcatggtcaaatgctggatgattgat
gcagacagtagacctaaatttaaggaactggctgctgaattttcgaggatggctcgagac
cctcaaagatatctagttattcagggtgatgatcgcatgaagcttcccagtccaaatgac
agcaagttctttcagaatctcttggatgaagaggacctggaagatatgatggatgctgag
gaatacctggtccctcaggctttcaacatcccacctcccatctatacttccagagcaaga
attgactcaaataggagtgaaattggacacagccctcctcctgcctacacccccatgtca
ggaaaccagtttgtataccgagacggagggtttgctgcagagcaaggagtgcctgtgccg
tacagagccacgaccagcacaatcccagaagctccagttgctcagggggctacagctgag
atttttgatgactcctgctgcaacggcaccctacgcaagccagtggcaccccatgttcca
gaggatagcagcacccagaggtacagcgccgaccccacggtgtttgccccagaacggagc
ccacgaggagagctggatgaagaaggttacatgacccctatgcgagataaacctaaacaa
gaatacctgaaccctgtggaagaaaacccttttgtttctcggagaaaaaatggagacctt
caagctttggataatcccgaatatcacaatgcttccaacggtcctcccaaggcagaggat
gagtatgtgaatgagccactgtacctcaacacctttgccaacgcgttggggaatgccggg
tacctgaagaacaatgtactgtctgtgccagagaaggccaagaaagcattcgacaaccct
gactactggaaccacagcctgccaccccggagcacccttcagcacccagactacctgcag
gagtacagcacaaaatatttttataaacaaaatggacggatccggcctattgtggcagag
aatcctgaatacctctctgagttctcgctgaagccaggcaccgtgctgcctcctccaccc
tacagacaccgaaacactgtggtgtaa

KEGG   Felis catus (domestic cat): 751824
Entry
751824            CDS       T02385                                 
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 precursor
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
fca  Felis catus (domestic cat)
Pathway
fca01521  EGFR tyrosine kinase inhibitor resistance
fca01522  Endocrine resistance
fca01524  Platinum drug resistance
fca04010  MAPK signaling pathway
fca04012  ErbB signaling pathway
fca04020  Calcium signaling pathway
fca04066  HIF-1 signaling pathway
fca04151  PI3K-Akt signaling pathway
fca04510  Focal adhesion
fca04520  Adherens junction
fca04530  Tight junction
fca05200  Pathways in cancer
fca05205  Proteoglycans in cancer
fca05206  MicroRNAs in cancer
fca05212  Pancreatic cancer
fca05213  Endometrial cancer
fca05215  Prostate cancer
fca05219  Bladder cancer
fca05223  Non-small cell lung cancer
fca05224  Breast cancer
fca05226  Gastric cancer
fca05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    751824 (ERBB2)
   04012 ErbB signaling pathway
    751824 (ERBB2)
   04066 HIF-1 signaling pathway
    751824 (ERBB2)
   04020 Calcium signaling pathway
    751824 (ERBB2)
   04151 PI3K-Akt signaling pathway
    751824 (ERBB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    751824 (ERBB2)
   04520 Adherens junction
    751824 (ERBB2)
   04530 Tight junction
    751824 (ERBB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    751824 (ERBB2)
   05206 MicroRNAs in cancer
    751824 (ERBB2)
   05205 Proteoglycans in cancer
    751824 (ERBB2)
   05230 Central carbon metabolism in cancer
    751824 (ERBB2)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    751824 (ERBB2)
   05226 Gastric cancer
    751824 (ERBB2)
   05219 Bladder cancer
    751824 (ERBB2)
   05215 Prostate cancer
    751824 (ERBB2)
   05213 Endometrial cancer
    751824 (ERBB2)
   05224 Breast cancer
    751824 (ERBB2)
   05223 Non-small cell lung cancer
    751824 (ERBB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    751824 (ERBB2)
   01524 Platinum drug resistance
    751824 (ERBB2)
   01522 Endocrine resistance
    751824 (ERBB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:fca01001]
    751824 (ERBB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    751824 (ERBB2)
   04090 CD molecules [BR:fca04090]
    751824 (ERBB2)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     751824 (ERBB2)
Protein kinases [BR:fca01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   751824 (ERBB2)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   751824 (ERBB2)
CD molecules [BR:fca04090]
 Proteins
  751824 (ERBB2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like APH Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 751824
NCBI-ProteinID: NP_001041628
Ensembl: ENSFCAG00000009903
UniProt: Q49LT4
LinkDB
Position
E1:40780250..40804241
AA seq 1260 aa
MELAAWCRWGLLLALLPSGATGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLHANASLSFLQDIQEVQGYVLIAHNQVKQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLKNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLA
LTLIDTNRSRACHPCSPMCEGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSAN
IQEFVGCKKIFGSLAFLPGSFEGDPASNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNSRLCFVHTV
PWDQLFRNPHQALLHSANRPEDECPGEGLACYPLCAHGHCWGPGPTHCVNCSQFLPGQEC
VEECRVLQGLPREYVKDRFCLPCHPECQPQNGSVTCLGSEADQCVACAHYKDPPFCVARC
SSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDEKGCPAEQRASPVTSIIAAVVG
ILLVVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDEDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLSPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPKPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGGAVENPE
YLAPRGRAAPQPHPPPAFSPAFDNLYYWDQDTSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq 3783 nt   +upstreamnt  +downstreamnt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctccggagcc
acgggcacccaagtgtgcaccggcacagacatgaagctgcggctcccagccagtcccgag
acccacctggacatgctccgccacctctaccagggctgtcaagtggtacagggcaacctg
gagctcacctacctgcatgccaatgccagcctctccttcctgcaggatatccaggaggtg
caaggctatgtgctcattgcccacaaccaagtgaaacaggtcccactgcagaggctacga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaatgga
gacccgctgaagaataccacccctgtcacaggggcctccccaggaggcctgcgggagctg
cagcttcgaagcctcacagagatcttgaaaggaggggtcttgatccagcggaacccccag
ctctgctaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggct
ctcacactgatagacaccaaccgctctcgggcctgccacccctgttctccgatgtgtgag
ggctcccgctgctggggagagagttctgaggattgtcagagcctgacgcgcactgtctgt
gccggtggctgtgcccgctgcaaggggccactgcccactgactgctgccatgagcagtgt
gctgccggctgcacgggccccaagcactctgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacagacacgtttgag
tccatgcccaatcccgagggccggtatacattcggcgccagctgtgtgactgcctgtccc
tacaactacctttctacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacagctgaggatggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctaggcatggagcacctgcgggaggcgagggcagtcaccagtgccaac
atccaagaatttgtcggctgcaagaagatctttgggagcctggcgtttctgccagggagc
tttgagggggacccagcctccaacactgcccccctgcagcctgagcagctcagagtgttt
gaggctctggaggagattacaggttacctgtacatctcagcgtggccagacagcttgcct
aacctcagtgtcttccagaacctcagagtaatccggggccgagttctgcatgacggtgct
tactcgctgacccttcaagggctgggcatcagctggctggggctgcgctcgctgcgggag
ctgggcagtgggctggccctcatccaccgcaactcccgcctctgcttcgtacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagcgccaaccggcca
gaggacgagtgcccgggtgagggcctggcctgctatccgctgtgcgcccacgggcactgc
tggggtccgggacccacccattgtgtcaactgcagccagttccttccgggccaggaatgc
gtggaggaatgccgagtactgcaggggctgccccgggagtatgtgaaggataggttctgt
ctgccatgccacccggagtgtcagccccagaatggctcagtgacctgcttgggctcggaa
gctgaccagtgtgtggcctgtgcccactacaaggaccctcctttctgtgtggctcgctgc
tccagtggggtgaaacctgacctctccttcatgcccatctggaagttcgcagatgaggag
ggcacgtgccagccatgccccatcaactgcacccactcctgtgcggacctggacgagaag
ggctgccccgccgagcagagagccagccctgtgacgtccatcattgccgctgtggtgggc
attctgctggtcgtggttgtggggctggtccttggcatcctgatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggagacggagctggtggagcccctg
acgcctagtggagccatgcccaaccaggctcagatgcgaatcctgaaagaaacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcactgtctacaagggcatctggatc
cctgacggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaatacatct
cccaaagccaacaaagaaatcttggacgaagcgtatgtgatggctggcgtgggctcccca
tatgtgtctcgccttctgggcatctgcctgacatccacggtgcagttggtgacacagctt
atgccttatggctgcctcttagaccatgtccgagaacaccgtgggcgcctaggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacttggaggatgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccacgtcaag
attacagattttgggctggctcggctgctggacattgacgagacagagtaccatgccgat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
catcagagtgacgtgtggagctacggtgtgactgtatgggaactgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
atagactctgaatgtcggccacgtttccgggagctggtggccgaattctcccgtatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggcccagcgagtcccttg
gacagcactttctaccgttcactgctggaggatgaggacatgggagacctggtggatgct
gaggagtacctggtaccccagcagggtttcttctgcccagaccctgccccaggcgctggg
ggcacagcccaccgcagacaccgcagctcatccaccaggagtggcggtggtgagctgaca
ctggggctggagccctccgaggaagagcctcccaagtctccactggcaccctcagaaggg
gctggctctgatgtgtttgatggcgacttgggaatgggggcagccaaggggctgcagagc
ctttccccacaggaccccagccctctacagcggtacagtgaggatcctaccgtaccccta
ccccctgagactgatggctacgttgcccccctgacctgcagtccccagcctgaatacgtg
aaccagccagaggtttggccaaagcccccatcgcccttagaaggccctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactctgtcccccaagactctttccccc
ggcaagaatggggttgtcaaagacgtttttgcctttgggggtgctgtggagaaccccgag
tacttggcaccccggggcagggctgcccctcagcctcaccctcctccagccttcagccca
gcctttgacaacctctattactgggaccaggacacatctgagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccccgaatacctggggctggacgtgccagtg
tga

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