KEGG   Felis catus (domestic cat): 101086207
Entry
101086207         CDS       T02385                                 
Name
(RefSeq) cytochrome b-245 heavy chain
  KO
K21421  NADPH oxidase 2 [EC:1.-.-.-]
Organism
fca  Felis catus (domestic cat)
Pathway
fca04066  HIF-1 signaling pathway
fca04145  Phagosome
fca04216  Ferroptosis
fca04217  Necroptosis
fca04613  Neutrophil extracellular trap formation
fca04621  NOD-like receptor signaling pathway
fca04670  Leukocyte transendothelial migration
fca04933  AGE-RAGE signaling pathway in diabetic complications
fca05010  Alzheimer disease
fca05020  Prion disease
fca05022  Pathways of neurodegeneration - multiple diseases
fca05140  Leishmaniasis
fca05171  Coronavirus disease - COVID-19
fca05415  Diabetic cardiomyopathy
fca05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    101086207
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    101086207
  09143 Cell growth and death
   04216 Ferroptosis
    101086207
   04217 Necroptosis
    101086207
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    101086207
   04621 NOD-like receptor signaling pathway
    101086207
   04670 Leukocyte transendothelial migration
    101086207
 09160 Human Diseases
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    101086207
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    101086207
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101086207
   05020 Prion disease
    101086207
   05022 Pathways of neurodegeneration - multiple diseases
    101086207
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101086207
   05415 Diabetic cardiomyopathy
    101086207
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101086207
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    101086207
Enzymes [BR:fca01000]
 1. Oxidoreductases
  1.-  
   1.-.-
    1.-.-.-
     101086207
Membrane trafficking [BR:fca04131]
 Others
  NADPH oxidases (Nox) and associated proteins
   NADPH oxidases
    101086207
SSDB
Motif
Pfam: NAD_binding_6 Ferric_reduct FAD_binding_8 FAD_binding_6 NAD_binding_1
Other DBs
NCBI-GeneID: 101086207
NCBI-ProteinID: XP_004000443
Ensembl: ENSFCAG00000003145
UniProt: M3VZS9
LinkDB
Position
X:33385703..33419837
AA seq 570 aa
MGNWVENEGLSIFVVLIWLGMNVFLFVWYYRIYALRRTFFYTQKLLGIALPLARAPAACL
NFNCMLILLPVCRNLLSFLRGSSACCSTRIRRQLDRNLTFHKMVAWMIALHTAIHTIAHL
FNVEWCVDARSNNSDPYLIALSDLGDNPNETYLNFARKRFKNPEGGLYVAVTRLAGITGI
VITLCLILIITSSTKTIRRSYFELFWYTHHLFVIFFIGLAIHGAERIVRGQTPQSLDEHH
HEICEKRISEWGKIKECPIPQFSGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVVITKV
VTHPFKTIELQMKKKGFKMEVGQYIFVKCPKVSRLEWHPFTLTSAPEEDFFSIHIRIVGD
WTEGLFNACGCDKQEFQDAWKLPKIAVDGPFGTASEDVFSYEVVMLVGAGIGVTPFASIL
KSVWYKYCNNATNLRLKKIYFYWLCRDTHAFEWFADLLQLLETQMLERNNAGFLSYNIYL
TGWDESQANHFAVHHDEEKDVITGLKQKTLYGRPNWDNEFKTIASQHPNTRIGVFLCGPE
ALAETLNKQCISNSESGPRGVHFIFNKENF
NT seq 1713 nt   +upstreamnt  +downstreamnt
atggggaactgggttgaaaatgagggactctccatctttgtcgttctaatatggctgggg
atgaacgtcttcctctttgtctggtactacagaatctatgcgttgagaaggacattcttt
tacactcaaaaacttctggggatcgcactgccattggccagggcccctgcagcctgcctg
aatttcaactgcatgctgattctgctgccagtctgtcgaaatctgctctccttcctcagg
ggttccagtgcgtgctgctcgacaagaattcgaagacaactggacaggaacctcaccttt
cataaaatggtggcatggatgatcgcacttcacactgcgattcatactattgcacatctg
tttaatgtggagtggtgtgtggatgcccgatccaacaattctgatccttatttaatagca
ctctctgaccttggagataatcctaatgaaacttacctcaattttgctcgaaagagattc
aagaatcctgaaggaggcctatatgtggctgtgactcggttggcaggcatcactggtatt
gtcatcacactgtgcctcatattaattatcacctcctccaccaaaaccatccggagatct
tactttgaactgttttggtacacacaccatctctttgtgatcttcttcatcgggctcgcc
atccacggagctgagcgcattgtacgtgggcagaccccacagagtttagacgaacaccat
cacgaaatttgtgagaaaaggatctcagaatggggaaaaataaaggaatgcccaatccca
cagttttctgggaaccctcctatgacttggaaatggattgttggtcccatgtttctgtat
ctctgtgagaggttggtacggttttggcgatctcaacagaaagtggtcatcaccaaggtg
gtcactcaccctttcaaaaccattgagctacagatgaagaagaagggattcaagatggag
gtgggacaatacattttcgtcaagtgccccaaggtgtccaggctggagtggcaccctttc
acgctgacctccgcccctgaggaagacttctttagcatccatattcgtatcgttggggac
tggacagaaggacttttcaatgcttgtggctgtgataaacaagagtttcaagatgcttgg
aaactacctaagatagctgttgatgggccctttggcaccgccagtgaagacgtgttcagt
tatgaggtggtgatgttggtgggagcagggatcggggtcacacccttcgcatccattctc
aagtccgtctggtacaaatattgcaataatgccaccaatctgaggctcaaaaagatatac
ttctactggctctgccgggacacgcacgcctttgagtggtttgccgacttgctgcagctg
ctggagacccagatgctggagaggaataacgctggcttcctcagctataacatctacctc
accggctgggatgagtctcaggccaatcactttgctgtgcatcacgatgaggagaaagac
gtgatcacaggcctgaaacaaaagaccttgtatggacggcccaactgggataatgaattc
aagacaattgcgagtcaacacccaaataccagaataggagttttcctctgcggacctgaa
gccttggcggaaaccctcaataaacagtgcatctccaactctgagtctggccctcgggga
gtgcatttcattttcaacaaggaaaacttctaa

KEGG   Felis catus (domestic cat): 101086376
Entry
101086376         CDS       T02385                                 
Symbol
NOX1
Name
(RefSeq) LOW QUALITY PROTEIN: NADPH oxidase 1
  KO
K08008  NADPH oxidase 1
Organism
fca  Felis catus (domestic cat)
Pathway
fca04380  Osteoclast differentiation
fca04933  AGE-RAGE signaling pathway in diabetic complications
fca05010  Alzheimer disease
fca05022  Pathways of neurodegeneration - multiple diseases
fca05208  Chemical carcinogenesis - reactive oxygen species
fca05417  Lipid and atherosclerosis
fca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101086376 (NOX1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101086376 (NOX1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101086376 (NOX1)
   05022 Pathways of neurodegeneration - multiple diseases
    101086376 (NOX1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101086376 (NOX1)
   05418 Fluid shear stress and atherosclerosis
    101086376 (NOX1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101086376 (NOX1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    101086376 (NOX1)
Membrane trafficking [BR:fca04131]
 Others
  NADPH oxidases (Nox) and associated proteins
   NADPH oxidases
    101086376 (NOX1)
SSDB
Motif
Pfam: NAD_binding_6 Ferric_reduct FAD_binding_8 FAD_binding_6 NAD_binding_1
Other DBs
NCBI-GeneID: 101086376
NCBI-ProteinID: XP_004000753
Ensembl: ENSFCAG00000007001
LinkDB
Position
X:complement(83147161..83171283)
AA seq 567 aa
MGNWVVNHWFSVLFLATWLGLNVFLFVHAFLSYEKADKYFYTREILGSALAWARASARCL
NFNSTLILLPVCRNLLSFLRGTCSFCRHALRKQLDHNLAFHKLVAYMICLHTATHIIAHL
FNFEHYSRSRWATDGSLASILSTLSQQERDEDSWINPIQSPNMTVEYVTFTSITGVTGVI
ITIALVLMVTSAMEFIRRSYFEVFWYTHRIFIVYFIGLGIHGIGGIVRGQTEESLNESHP
HRCAEFFEQWSCDHDHDSHCKHPRFEGLPAESWKWILAPGILYIFERILRFYRSKQKVVI
TKVVMHPSKVLELQMSKRGFIMEVGQYIFVNCPSISYLEWHPFTLTSAPEEDFFSIHIRA
VGDWTENLIRAFEQQHSPIPRIEVDGPFGTVSEDVFQYEVAVLVGAGIGVTPFASILKSI
WYKFRHADHNLKTQTIYFFWICRETGAFAWFSDLLASLEHEMEELGKVDFLNYHLFLTGW
DTNIAGHAALNFDKATDILTGLKQKTSFGRPMWDNEFSTIANAHPKSVVGVFLCGPQTLA
KSLSKCCHQYSSLDPRKVQFYFNKEDF
NT seq 1704 nt   +upstreamnt  +downstreamnt
atgggcaactgggtggttaaccactggttctcagttttgtttctggctacttggttgggg
ctgaatgttttcctgtttgtgcatgccttcctgtcatatgaaaaagccgataagtacttc
tatacaagagaaatcctggggtcggcgttggcctgggcccgagcctctgctcgctgcctg
aattttaacagcacgctgatcctgcttcctgtgtgtcgaaatctgctgtccttcctgagg
ggcacctgctcattttgcaggcatgccctgagaaagcaactggatcacaatctcgccttc
cacaaactggtagcatatatgatctgcctacacacagctactcatatcattgcacacctg
ttcaactttgaacactacagcagaagccgatgggccacagatggatcccttgcttccatt
ctctccaccctatctcaacaagagagagatgaagattcttggataaatcctatccagtcc
ccaaacatgacagtggagtatgtgacatttaccagcatcaccggtgtcactggagtgatc
atcacaatagctctggttctcatggtgacttcagctatggagtttatccggaggagttat
tttgaggtcttctggtatactcatcgtatttttatcgtctacttcattggtttagggatt
catggcattggtggaattgtccggggtcaaacagaagagagcctgaatgagagtcatcca
cacaggtgtgcagaatttttcgagcagtggtcatgtgatcatgatcatgactcccactgc
aagcatccccgatttgaagggctccctgctgagtcttggaagtggatacttgcaccaggc
attctttatatctttgaaaggattctccgattttatcgttcaaagcagaaggttgtgatt
accaaggttgtcatgcacccatccaaagttttggaattgcagatgagcaagcgtggcttc
atcatggaagtgggacagtatatttttgttaattgtccttcaatctcttacttggaatgg
catccctttactctgacctctgctccagaggaagacttcttctccattcatatcagagca
gtgggagactggacagaaaatctcataagggcttttgagcaacaacattcaccaattccc
aggattgaggtggatggtccctttggcactgtcagtgaagatgttttccagtatgaagtg
gctgtgttggttggagcaggaattggggtcaccccctttgcttccatcttaaaatctatc
tggtacaagtttcggcacgcagatcacaaccttaaaacacaaacgatctatttcttctgg
atctgcagggagacaggtgcctttgcctggttcagtgacctattggcttctctggaacat
gagatggaagaattaggcaaagtggattttctaaactaccatctctttctcaccggatgg
gacaccaacatcgctggtcatgccgcattaaactttgacaaggccactgacatcctgaca
ggtctgaaacagaaaacctcatttgggagacccatgtgggacaatgagttttctacaata
gctaatgcccaccccaagtccgtggtgggagtctttttatgtggtcctcagactttggca
aagagcctgagcaaatgctgtcaccagtactccagtctagatcctaggaaggttcaattc
tacttcaacaaagaagatttctga

KEGG   Felis catus (domestic cat): 101089891
Entry
101089891         CDS       T02385                                 
Symbol
NOX4
Name
(RefSeq) NADPH oxidase 4 isoform X1
  KO
K21423  NADPH oxidase 4 [EC:1.6.3.-]
Organism
fca  Felis catus (domestic cat)
Pathway
fca04933  AGE-RAGE signaling pathway in diabetic complications
fca04936  Alcoholic liver disease
fca05010  Alzheimer disease
fca05022  Pathways of neurodegeneration - multiple diseases
fca05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:fca00001]
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101089891 (NOX4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101089891 (NOX4)
   05022 Pathways of neurodegeneration - multiple diseases
    101089891 (NOX4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101089891 (NOX4)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101089891 (NOX4)
Enzymes [BR:fca01000]
 1. Oxidoreductases
  1.6  Acting on NADH or NADPH
   1.6.3  With oxygen as acceptor
    1.6.3.-
     101089891 (NOX4)
SSDB
Motif
Pfam: Ferric_reduct NAD_binding_6 FAD_binding_8 Ni_hydr_CYTB NAD_binding_1 Autoind_bind
Other DBs
NCBI-GeneID: 101089891
NCBI-ProteinID: XP_011284840
UniProt: M3XET3
LinkDB
Position
D1:45600697..45771264
AA seq 578 aa
MAVSWRSWLANEGVKHLCLFVWLSLNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRAS
ASVLNLNCSLILLPMCRTLLAYLRGSQKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHV
AAHLVNALNFSVNYSEDFVELNAARYPDEDPRKLLFTTVPGLTGVCMVLVLFLMITASTY
AIRVSNYDIFWYTHNLFFVFYMLLMLHVSGGLLKYQTNLDTHPPGCINLNGTHYQNIHLQ
DYLSEHFRESFPEGFAKPDELTQKRFVKICMEEPRFQANFPQTWLWISGPLCLYCAERLY
RCIRSNKPVTIISVIRHPSDVMEIRMVKENFKARPGQYIILHCPSVSALENHPFTLTMCP
TKTKATFGVHLKIVGDWTERFRDLLLPPSSQDSEILPFIQSRNYPKLYIDGPFGSPFEES
LNYEVSLCVAGGIGVTPFASILNTLLDDWEPYKLRRLYFIWVCRDIQSFRWFADLLCVLH
NKFWQENRPDYVNIQLYLSQTDGIQKIIGEKYQALNSRLFIGRPRWKLLFDEIAKCNRGK
TVGVFCCGPSSISKTLHKLSNRNNSYGTRFEYNKESFS
NT seq 1737 nt   +upstreamnt  +downstreamnt
atggctgtgtcctggaggagctggctggccaacgaaggggttaaacacctctgcctgttt
gtctggctctccctgaatgttttgcttttctggaaaaccttcctgctgtataaccaaggg
ccagagtatcactacctccaccagatgttagggctaggattgtgtctaagcagagcctcc
gcatctgttcttaacctcaactgcagccttatccttctacccatgtgccggacactcctg
gcctaccttcgaggatcccagaaggttccaagcaggagaaccagaagactgttggataaa
agcagaacattccatataacctgtggtgttactatctgcattttttcaggtgtgcacgtg
gctgcccatctggtgaacgccctcaatttctcagtgaactacagtgaagatttcgtggaa
ctgaatgctgcaagatacccagatgaggatcctagaaaacttctcttcacaactgttcct
ggcctgacaggggtctgcatggtgctggtgctcttcctgatgattacagcttctacatac
gcaatacgagtttctaattatgacatcttctggtatactcataatctcttctttgtcttc
tacatgctgctgatgttgcatgtttcaggagggctgctgaagtatcaaactaatttagat
acccaccctcctggctgcatcaatcttaatggaacccactaccagaatattcatttacaa
gattatctctcagaacattttcgtgaatcttttcctgaaggatttgcaaagccagatgaa
cttacccaaaagagatttgtgaagatttgtatggaagagcccaggttccaagctaatttt
ccacagacttggctttggatttctggacctttgtgcctgtattgtgctgaaagactttac
aggtgtatccggagcaataagccagtcaccatcatctcggtcatacgtcatccctcagat
gtcatggaaatccgaatggtcaaagaaaattttaaagcgagacctggccagtatattatt
ctacattgtcccagtgtgtctgcgttagaaaaccatccatttaccctcacaatgtgtcct
actaaaaccaaagcaacatttggtgtccacctcaaaatagtaggagactggacagaacga
tttcgagacttactacttcctccatctagtcaagactctgagattctacccttcattcaa
tctagaaattatcccaagctgtacattgatggtccatttggaagtccatttgaggaatcc
ttgaactacgaggttagcctctgtgtggccggaggcattggagtaactccatttgcatca
atactcaacaccctgctggatgactgggaaccgtacaagctcagaagactatattttatt
tgggtgtgcagagacatccagtccttccgttggtttgcagacttactctgtgtgttacat
aacaagttttggcaagagaacagacctgactatgtcaacatccagctgtacctcagtcaa
acagatgggatacagaagataattggagaaaaataccaagcactgaattcaagacttttt
attggacgtcctcggtggaaacttctgtttgatgaaatagcaaaatgtaacagagggaaa
acagttggtgttttctgctgtggacccagttcaatttctaagacccttcataaactgagt
aaccgaaacaattcatatgggacaagatttgaatacaataaagaatctttcagctga

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