Felis catus (domestic cat): 101087258 Help Entry 101087258         CDS       T02385                                  Symbol ITGB2 Name (RefSeq) integrin beta-2   KO K06464   integrin beta 2 Organism fca  Felis catus (domestic cat) Pathway fca04015   Rap1 signaling pathway fca04145   Phagosome fca04390   Hippo signaling pathway fca04514   Cell adhesion molecules fca04610   Complement and coagulation cascades fca04613   Neutrophil extracellular trap formation fca04650   Natural killer cell mediated cytotoxicity fca04670   Leukocyte transendothelial migration fca04810   Regulation of actin cytoskeleton fca05133   Pertussis fca05134   Legionellosis fca05140   Leishmaniasis fca05144   Malaria fca05146   Amoebiasis fca05150   Staphylococcus aureus infection fca05152   Tuberculosis fca05166   Human T-cell leukemia virus 1 infection fca05323   Rheumatoid arthritis fca05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     101087258 (ITGB2)    04390 Hippo signaling pathway     101087258 (ITGB2)   09133 Signaling molecules and interaction    04514 Cell adhesion molecules     101087258 (ITGB2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     101087258 (ITGB2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     101087258 (ITGB2)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     101087258 (ITGB2)    04613 Neutrophil extracellular trap formation     101087258 (ITGB2)    04650 Natural killer cell mediated cytotoxicity     101087258 (ITGB2)    04670 Leukocyte transendothelial migration     101087258 (ITGB2)  09160 Human Diseases   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101087258 (ITGB2)   09171 Infectious disease: bacterial    05133 Pertussis     101087258 (ITGB2)    05134 Legionellosis     101087258 (ITGB2)    05150 Staphylococcus aureus infection     101087258 (ITGB2)    05152 Tuberculosis     101087258 (ITGB2)   09174 Infectious disease: parasitic    05146 Amoebiasis     101087258 (ITGB2)    05144 Malaria     101087258 (ITGB2)    05140 Leishmaniasis     101087258 (ITGB2)   09163 Immune disease    05323 Rheumatoid arthritis     101087258 (ITGB2)   09166 Cardiovascular disease    05416 Viral myocarditis     101087258 (ITGB2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:fca04131]     101087258 (ITGB2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:fca04147]     101087258 (ITGB2)    04515 Cell adhesion molecules [BR:fca04515]     101087258 (ITGB2)    04090 CD molecules [BR:fca04090]     101087258 (ITGB2) Membrane trafficking [BR:fca04131]  Endocytosis   Phagocytosis    Integrins (complement receptors)     101087258 (ITGB2) Exosome [BR:fca04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    101087258 (ITGB2) Cell adhesion molecules [BR:fca04515]  Integrins   Integrin beta subunits    101087258 (ITGB2) CD molecules [BR:fca04090]  Proteins   101087258 (ITGB2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Integrin_beta Integrin_b_cyt PSI_integrin Integrin_B_tail EGF_2 I-EGF_1 Motif Other DBs NCBI-GeneID:  101087258 NCBI-ProteinID:  XP_011284106 LinkDB All DBs Position C2:1755806..1781525 Genome browser AA seq 770 aa AA seqDB search MLPQHFPLLTLVGLLALWSALGQKCTKFKVSNCRDCVESGPGCAWCQKLNFTGLGEPDSV RCDTREQLLLKGCAADDIIDPRSLAETYYDQEGVQKQLSPQKVTLHLRPGQAAAFNVTFR RAKGYPIDLYYLMDLSYSMLDDLINVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFV NTHPEKLKNPCPNKEKECQAPFAFRHVLKLTNNSHQFQTEVGKQLISGNLDAPEGGLDAM MQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNMYKRSNEFD YPSVGQLAHKLAESNIQPIFAVTKRMVKTYEKLTEVIPKSAVGELSEDSSNVVQLIKNAY NKLSSRVFLDHNTVPNTLRVTYDSFCSNGVSQVDQPRGDCDGVQINVPITFQVKVTATEC IHEQSFVIRALGFTDTVTVHVLPQCECHCRDMSQNRGLCGDRGSMECGICRCDAGYIGKN CECQTQGRSSQELEGSCRRDNNSLICSGLGDCLCGQCVCHQSDIPNKSIFGRFCECDNVN CERYDGLVCGGKERGTCSCGKCSCNPGFEGSACQCDRSTRGCLNPDGFECNGRGRCVCNV CECDTGYQPPLCLECLGCPSPCGRYLLCAQCLKFDPSHSGSNCTSVCGNVGLLNKPPEKG RTCKERDVDGCWITYTLRQRVGRDSYDIYVDDSRECATGPQVAPIVGGIVAGVVLIGILL LGIWKALTHVSDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES NT seq 2313 nt NT seq  +upstreamnt  +downstreamnt atgctgccccagcacttcccgctcctcaccctggtgggtctgctcgccctctggtccgcc ctcggccagaagtgtaccaagttcaaggtcagcaactgccgggactgcgtggagtcgggc cccggctgtgcctggtgccagaagctgaacttcactgggctgggggagccagactccgtt cgctgcgacacccgggagcagctgctattgaagggatgtgcagctgacgacatcatagac cccaggagcctggccgagacctactacgaccaggagggcgtccagaagcagctatcccca cagaaagtgacactccacctgagaccaggtcaggcggctgccttcaacgtgaccttccgg cgggccaagggctaccccatcgacctgtactacctgatggacctctcctactccatgctg gacgacctcatcaacgtcaagaagctggggggtgatctgctccgggctctcaacgaaatc accgagtcgggccgcatcggcttcgggtccttcgtggacaagacggtgctccccttcgtg aacacgcaccccgagaagctgaagaacccgtgccccaacaaagagaaggagtgccaggcg ccgttcgccttcaggcacgtgctgaagctcaccaacaactcccaccagttccagaccgag gtggggaagcagctcatttccggaaacctggacgcccccgagggcggtctggacgccatg atgcaggtcgccgcttgcccggaggaaatcggctggcgcaatgtcactcggctgctggtg ttcgccacggacgacggcttccactttgcgggtgacgggaagctgggcgccatcctgacc cccaatgacggccgctgtcacctagaggacaacatgtacaaaaggagcaatgaatttgac tacccatcggtgggccagctggctcacaaactggctgaaagtaacatccagcccatcttc gccgtgaccaagagaatggtgaaaacctatgagaaactcaccgaggtcatccccaagtca gcggtgggggagctgtcagaggattccagcaacgtggtgcagctcattaagaacgcctac aataaactctcctccagggtctttctggaccacaacactgtccccaacaccctgagagtc acctatgactccttctgcagtaatggagtatcacaggtggaccagcccagaggagactgt gacggagtccagatcaacgtcccgatcaccttccaggtgaaggtcacggccacagagtgc atccatgagcagtcctttgtcatccgggccctgggcttcacggacacggtgaccgttcac gtccttccccagtgcgagtgccattgcagggacatgagccagaaccgcggcctctgtggt gacaggggctccatggagtgcggcatctgcaggtgcgacgccggctacatcgggaagaac tgtgaatgccagacgcagggccggagcagtcaggagctggagggcagctgccggagggac aacaactccctcatctgctcggggctgggggactgcctgtgcgggcagtgcgtgtgccac cagagcgacatccccaacaagagtatcttcgggcgcttctgcgagtgcgacaacgtcaac tgcgagcgctatgatggcctggtctgcgggggcaaggagcggggcacctgttcctgcggc aagtgctcctgcaacccgggcttcgagggctccgcgtgccagtgtgacaggtccacccgg ggctgcctgaaccccgacggctttgagtgcaacgggcgcggccgctgtgtctgcaacgtg tgtgagtgtgacaccggctaccagccgcccctgtgcctggagtgcctgggctgcccgtcg ccctgcggccgctacttgttgtgcgcccagtgcctgaaatttgacccgagccactcgggg agtaactgtacctcggtgtgcgggaacgtgggcctgctgaacaagcccccggagaagggg cgcacgtgcaaggagcgggacgtggacggctgctggatcacctacacgctgcggcagcgg gttggcagggacagctatgacatttacgtggatgacagccgagagtgtgcgacgggcccc caagttgcccccatcgtggggggcatcgtggcgggggtcgtactcatcggcatcctcctg ctgggcatctggaaggctctgacccacgtgagtgacctcagggagtacaggcgatttgag aaggagaagctcaagtcccagtggaacaatgacaacccccttttcaagagcgccaccacg acagtcatgaacccaaagtttgctgagagttaa

Felis catus (domestic cat): 101087957 Help Entry 101087957         CDS       T02385                                  Symbol ITGAM Name (RefSeq) integrin alpha-M isoform X1   KO K06461   integrin alpha M Organism fca  Felis catus (domestic cat) Pathway fca04015   Rap1 signaling pathway fca04145   Phagosome fca04514   Cell adhesion molecules fca04610   Complement and coagulation cascades fca04613   Neutrophil extracellular trap formation fca04640   Hematopoietic cell lineage fca04670   Leukocyte transendothelial migration fca04810   Regulation of actin cytoskeleton fca05133   Pertussis fca05134   Legionellosis fca05140   Leishmaniasis fca05146   Amoebiasis fca05150   Staphylococcus aureus infection fca05152   Tuberculosis fca05202   Transcriptional misregulation in cancer fca05221   Acute myeloid leukemia Brite KEGG Orthology (KO) [BR:fca00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     101087957 (ITGAM)   09133 Signaling molecules and interaction    04514 Cell adhesion molecules     101087957 (ITGAM)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     101087957 (ITGAM)   09142 Cell motility    04810 Regulation of actin cytoskeleton     101087957 (ITGAM)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     101087957 (ITGAM)    04610 Complement and coagulation cascades     101087957 (ITGAM)    04613 Neutrophil extracellular trap formation     101087957 (ITGAM)    04670 Leukocyte transendothelial migration     101087957 (ITGAM)  09160 Human Diseases   09161 Cancer: overview    05202 Transcriptional misregulation in cancer     101087957 (ITGAM)   09162 Cancer: specific types    05221 Acute myeloid leukemia     101087957 (ITGAM)   09171 Infectious disease: bacterial    05133 Pertussis     101087957 (ITGAM)    05134 Legionellosis     101087957 (ITGAM)    05150 Staphylococcus aureus infection     101087957 (ITGAM)    05152 Tuberculosis     101087957 (ITGAM)   09174 Infectious disease: parasitic    05146 Amoebiasis     101087957 (ITGAM)    05140 Leishmaniasis     101087957 (ITGAM)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:fca04131]     101087957 (ITGAM)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:fca04147]     101087957 (ITGAM)    04515 Cell adhesion molecules [BR:fca04515]     101087957 (ITGAM)    04090 CD molecules [BR:fca04090]     101087957 (ITGAM)    00536 Glycosaminoglycan binding proteins [BR:fca00536]     101087957 (ITGAM) Membrane trafficking [BR:fca04131]  Endocytosis   Phagocytosis    Integrins (complement receptors)     101087957 (ITGAM) Exosome [BR:fca04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    101087957 (ITGAM) Cell adhesion molecules [BR:fca04515]  Integrins   Integrin alpha subunits    101087957 (ITGAM) CD molecules [BR:fca04090]  Proteins   101087957 (ITGAM) Glycosaminoglycan binding proteins [BR:fca00536]  Heparan sulfate / Heparin   Adhesion molecules of cell surface    101087957 (ITGAM) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ITGAX-like_Ig_3 VWA FG-GAP Integrin_A_Ig_2 VWA_2 Integrin_A_Ig_1 FG-GAP_3 Integrin_alpha Integrin_A_Ig_3 Motif Other DBs NCBI-GeneID:  101087957 NCBI-ProteinID:  XP_006942178 Ensembl:  ENSFCAG00000005205 LinkDB All DBs Position E3:complement(17163906..17205351) Genome browser AA seq 1159 aa AA seqDB search MTHRVLLLTGFLLLPALALLCHGFNLDTKHATLFQENAAGFGQSVVQLEGSRLVVGAPQE IKAANQTGGLYQCDYSTGKCEPISLEVPLEAVNMSLGLSLAFATNPFRLLACGPTVHQTC KENTYVNGLCFLFGSNLRQQPQRFPESLRECPRQDSDIAFLIDGSGSIIQSDFQKMKDFV STVMGQFKNSKTLFSLMQYSEDFQTHFTFNEFKKSPNPSLLVRPIEQLRGRTHTATGIRK VVRELFQSSSGAREKAFKILVVITDGEKFGDPLEYKDVIPEADKEGIIRYVIGVGAAFNS PKTREELNTIASKPSRDYVFRVNNFEALKTIQNQLQEKIFAIEGTQTGSTSSFEHEMSQE GFSAAITSNDLLLGAVGSFDWAGGAFLYVSKDKFTFINTTRVDSDMNDAYLGYAAEVIWR SRVQNLVLGAPRYQHTGLVVMFRENAGTWETNTVIKGSQIGSYFGASLCSVDMDKDGSSD LVLIGAPHYYEPTRGGQVSVCPLPRGQRARWQCETVLHGVQGHPWGRFGAALTALGDVNG DKLTDVAIGAPGEQENRGAVYLFHGTSRPGISPSHSQRIEGSQLSPTLQYFGQSLSGGQD LTMDGLVDLAIGAQGHVLLLRSQPVLRLEVTMEFTPKEVARNVFECLAKVVKGQTAGEVR VCLRVRKNTRDRLREGEIQSNITYDLALEPTLPHPRVVFDETKNSTRRQTRILRLNQECE TLKLLLPYCVEDSVNPIILHFNFSLVGKPLSLFGNLQPVLAVDAQRLFTASFPFEQNCGS DNICHDDLSITFTFMGLDTLVVGGPRDLNVTLTVRNQGEDSYRTQVTFFYPPGLSYRRMS VTQKQRSQRPWRLTCESEDSTNGPEALKNSSCNISHPIFPNYSEITFNITFGVESDAFFG NRLLLKANVTSENNTTKTNKTEFQLELPVKYTVFVVVTSHEVSTKYLSFIASEKTSHSIK HQYEVNNLGQRSLPIIVVFWVPIKLNQVAVWDNLQVTLSQNLSRTCNTTENSPPLSDFMA ELKRAPVVNCSIAVCQRIQCDIPSFSIQEKVNITLQGKLSFDWYIKTSANYLQVVTTAEV LYDDSKFALLPGQEAFLRAQIETKVEPNEVHNPVPLIVGSSVGGLVLLALITAGLYKLGF FKRQYKDMMSEAGPNAQPQ NT seq 3480 nt NT seq  +upstreamnt  +downstreamnt atgactcacagagttcttctgttaacaggctttctcctccttccagccttggccttatta tgtcatgggttcaacctggatactaagcatgcaacgctattccaagagaatgcagcgggc ttcgggcaaagtgtggtccagcttgagggatcccggttggtggttggagccccccaggag ataaaggctgccaaccaaacaggtggcctctaccagtgtgactacagcacgggcaagtgt gagcctatctccctggaggtccccctggaggcggtgaacatgtctctgggcctgtctctg gcatttgccaccaacccttttcgactgctggcctgtggtcccactgtgcaccaaacttgt aaggagaacacctatgtgaatggcttatgcttcctgtttggatccaacctacggcagcag ccccagagattcccagagagcctcagagagtgccctcggcaagacagtgatattgccttc ttgattgatggttctggtagcatcatccagagtgactttcagaagatgaaggattttgtc tcaactgtgatgggtcaattcaagaattccaaaaccttgttttctttaatgcagtactct gaagacttccagactcatttcacctttaatgaattcaagaaaagccctaacccatcattg ctggtgaggccaatagaacagttgcgtgggcggacacacactgccacaggaatccgcaaa gtagtaagagaattgtttcagagcagtagtggagcccgggagaaagcctttaagatccta gtagtcatcacggatggagaaaagtttggcgatcccttggagtacaaggatgtcattcct gaagcagacaaagaggggatcattcgctatgtcattggggtgggagctgctttcaacagt ccaaaaactcgtgaagagcttaataccattgcatcaaagccttctcgtgattatgtgttc cgggtgaataactttgaagctctgaagaccattcaaaaccagcttcaggaaaagatcttt gcaattgagggtactcagacaggaagtaccagctcctttgaacatgagatgtctcaggaa ggcttcagtgctgccatcacctctaatgatctcttgctaggtgctgtgggaagctttgac tgggctggtggagcttttctgtatgtgtcaaaggacaaattcaccttcatcaacacaacc agggtagattcagacatgaatgatgcttacttgggttatgctgccgaagtcatatggagg agcagggtgcaaaatctggttcttggggcacctcgatatcagcacactggcctggtggtg atgtttagagagaatgctggtacctgggagaccaacactgttatcaagggtagccagatt ggctcctactttggggcctccctctgctctgtggacatggacaaagatggcagctctgac ctggtccttattggggccccccattactacgagccgacaagggggggccaggtgtctgtg tgccccttgcctcgggggcagagggctagatggcaatgtgagactgttctccatggggtg cagggccacccctggggccgctttggggcagccctgacagcgctgggagatgtgaatgga gacaagctgacagatgtggccattggggccccaggagagcaggagaaccggggtgctgtt tacctatttcatggaacctcaagaccgggcattagcccttcccacagccagcggattgaa ggctcccagctctcccccacactacaatattttggtcagtcactgagtgggggccaggac ctcacaatggatggactggtggacctggctataggagcccaaggccatgtactgctgctt agatcccagcctgtgctgagacttgaggtgaccatggagttcacacccaaagaagtggca aggaatgtgtttgaatgtcttgcaaaggtggtgaaaggtcagactgctggggaggttaga gtttgccttcgtgtccgcaagaatacacgggacaggctaagagaaggagagattcagagc aacatcacatatgacttggctctggagccaactctcccacatccccgagttgtctttgat gagacaaagaacagcacacgcagacagacaagaatcttgaggctgaatcaagaatgtgag accctaaagctactgttaccgtattgtgtggaggattcagtgaaccccatcatcctgcac ttcaacttctctctggtggggaaacccttgtccttattcgggaacctccagccagtgctg gctgtggatgcacagagactcttcacagcttcgtttccttttgagcagaattgtggcagt gacaacatttgccatgatgacctcagcatcaccttcacttttatgggtctggataccctg gtggtgggtggtccccgagacctgaatgtgacattgactgtgagaaaccagggcgaggac tcctacaggactcaagttaccttcttctacccacctggcctgtcctataggaggatgtca gtgacccagaagcagcgctcacagcgaccatggcgcctgacttgtgagtctgaagactcc accaatgggcccgaggctttgaagaatagcagctgcaacataagccaccccatcttccca aactactcagagatcacctttaatatcacatttggtgtggaatctgatgctttctttgga aacagactactactcaaggccaatgtgaccagtgagaacaacacaactaagaccaacaaa actgaattccaactggagttgcctgtgaaatacactgtcttcgtggtggtcacaagccat gaagtctccaccaaatatctcagcttcatagcctcagagaagaccagccacagtataaag caccagtatgaggtcaacaacttgggacagaggagcctccccatcattgtggtcttctgg gtgcctatcaagctgaaccaggtggctgtgtgggacaacctccaggtcaccctttcccag aacctctccagaacatgcaacaccacggagaattctccccctctctctgacttcatggca gagcttaagagggccccagtggtgaactgctccattgctgtctgccagagaatccagtgt gacatcccatccttcagcatccaggaaaaagtcaacattaccctccaaggcaaactctca tttgactggtatatcaagacttcagcaaactaccttcaggttgtgaccacggcagaggtc ttgtatgatgattcgaagtttgccctgcttccaggacaggaggcatttctgagggcccag atagaaaccaaagtggagccaaatgaagtgcacaaccctgtaccacttatagtgggcagc tcagtgggggggctggtgcttctggccctcatcaccgctggactgtacaagcttggcttc ttcaaacggcagtacaaggacatgatgagtgaagctggtcccaatgcccagccccagtaa

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