Felis catus (domestic cat): 101091689
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Entry
101091689 CDS
T02385
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor isoform X2
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca05200
Pathways in cancer
fca05223
Non-small cell lung cancer
fca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101091689 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101091689 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
101091689 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101091689 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
fca04090
]
101091689 (ALK)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101091689 (ALK)
Protein kinases [BR:
fca01001
]
Receptor tyrosine kinases (RTK)
ALK family
101091689 (ALK)
CD molecules [BR:
fca04090
]
Proteins
101091689 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
MAM
Pkinase
Gly_rich
Ldl_recept_a
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
101091689
NCBI-ProteinID:
XP_003984408
Ensembl:
ENSFCAG00000001792
LinkDB
All DBs
Position
A3:118882145..119557810
Genome browser
AA seq
1625 aa
AA seq
DB search
MGALGLLGLLLLLLSAAALGSGTGTGTGTGTGHLAGSPAVGPALQPREPLSYSRLQRKSL
AVDFVVPSLFRVYARDLLLPPSSFLEPRARRPEARGSLALDCAPLLRLVGQPPGVSWTEG
SSSPAPAQARTLTRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPEEVIAGLLQFNLS
ELFSWWIHHGEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLFQILGIGHSSSESPT
NLPSPPPDPFVWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWR
RVPSEEASQMDLLDGPETEHSKEMPRGSFLLLNTSANSKHTILSPWMRSSSEHCSLAVSV
HRHLQPSGRYVAQLLPHNEAGREILLVPTPGKHGWTVLQGRIGRPENPFRVALEYISSGN
RSLSAVDFFALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHRDCAQGEDEGQLC
SKLPAGFYCNFEDGFCGWTQGTLAPHTSQWQVRTLKDARVQDHQGHALLLSTTDVPTSES
ATVTSTTFPAPMKNSPCELRMSWLIRGVLQGNVSLVLVENKTGKEQSRMVWHVATNEGLS
LWQWTVLPLLDVADRFWLQIVAWWGQGSRATVAFDNISISLDCYLTISGEDKVSQDTAPK
SRNLFERNPNKEPKPWENTPRETPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYRNSNLS
VVVGSEGPLKGIQTWKVPVTDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKGDTL
YILVGQQGEDACPSTNRLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMK
DGVPVPLIIAAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLW
SGKSLLEGATGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMD
GEDGVSFISPLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHG
TVLAEDGVSCIVSPTPEPHLPLSLVLSVVTSALVAALVLAFSGIMIVYRRKHQELRAMQM
ELQSPEYKLSKLCTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVY
EGQVSGVPSDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALP
RFILLELMAGGDLKSFLRETRPRPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIA
ARNCLLTCPGPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTD
TWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPE
DRPNFAIILERIEYCTQDPDVINTALPIEYGPLVEEEEKVPMRPQDPEGIPPLLVSPPQA
KREEGQDPAAPPPLPSTSSGKASKKPTAAELSVRVTRGPAVEGGHVNMAFSQSNPPSELH
KVQGSRNKPTSLWNPTYGSWFTEKPTKKNNPPAKKEHHERGNLGREGSCTVPPNVATGRL
PGASLLLEPSSLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEATTAPGTSHYEDTILK
NQPGP
NT seq
4878 nt
NT seq
+upstream
nt +downstream
nt
atgggagccttagggctcctagggctgctgctactgctgctttcagcggcagccttgggc
tccggaaccggaaccgggaccgggactggcaccggccatctcgccggctcacccgccgtg
ggaccagctctgcagcctcgggagcctctcagctactcacgtctgcagaggaagagcctg
gcggtggactttgtggtgccctcgcttttccgtgtctatgctcgggacctgctgctgccg
ccttcgtccttcttggagccgagggccagacggcctgaggcacgcggctccttggctctc
gactgcgccccactacttaggctggtagggcaaccgcccggggtctcctggacggaaggc
tccagctcgccagcccctgcccaggcacggacgctgaccagggtgctgaagggcggctcg
gttcgcaagctccggcgcgccaagcagctggtactggagctgggagaggaggcgatcctt
gagggctgtgtcgggcccccagaggaggtgattgcgggactgctccagttcaacctcagc
gagctgttcagctggtggattcaccacggcgaagggcggttgaggatccgcctgatgcca
gagaagaaggcttcggaagtgggcagagagggaaggctgtccgcggcgatccgtgcctcc
cagccccggcttctcttccagatcttggggatcggtcacagctcctcggagtctccgaca
aacctgccttctcctcctcctgatccttttgtatggaatctgacctggataatgaaagat
tccttccctttcctgtctcatcgcagtcgatacggtctggagtgcagctttgacttcccc
tgtgagctggagtactccccaccactccacgacctccggaaccagagctggtcctggcgt
cgagtcccctctgaggaggcctcccagatggacctgttggacgggcctgagacagagcac
tccaaggagatgcccagaggctccttcctgctcctcaacacctcagcaaactccaagcac
accatcctgagcccatggatgaggagcagcagcgagcactgcagcctggctgtctcagtg
cacaggcatctgcagccttctgggaggtatgtcgcccagctactgccccacaacgaggct
ggaagagagatccttctggtacccactccgggaaagcatggttggacagtgcttcaggga
agaattgggcgaccagagaacccattccgagtggccctggaatacatctctagtggaaac
cgaagcttgtctgcagtggacttctttgccctgaagaactgcagtgaaggaacatccccg
ggctccaagatggccttgcagagttccttcacctgctggaatgggacagtcctccagctc
gggcaggcctgcgacttccaccgggactgcgcccagggagaagacgagggccagctgtgc
agtaaactccctgctgggttttactgcaacttcgaagatggcttctgtggctggacccag
ggcacgctcgcaccccacacctcccagtggcaggtcaggaccctgaaggatgcccgggtc
caggaccaccaaggccatgctctgttgctcagcactactgatgtccctacttctgaaagt
gctacagtgaccagcactacgtttcccgccccgatgaagaactctccatgtgagctccga
atgtcctggctcatccgtggagtcttgcagggaaacgtctccttggtcctggtggagaac
aaaactgggaaggaacaaagtagaatggtctggcatgttgccactaatgaaggcttgagc
ctgtggcagtggacagtgctgcctcttctcgatgtggctgacaggttctggctgcagatt
gttgcgtggtgggggcaaggatccagagcgaccgtggcttttgacaatatctccatcagc
ctggactgctacctcaccatcagtggggaggacaaggtgtcacaggatacagcacccaaa
tcgagaaatctgtttgagagaaacccaaacaaggagccgaaaccctgggaaaatacacca
agagagacccccatctttgaccctacagttcactggctgttcaccacgtgcggggccagt
gggccccatggccccacacaggcccagtgtaacaacgcctaccggaattccaacctgagc
gtggtagtgggaagcgaggggcccctgaagggcatccagacctggaaggtgccagtcacc
gacacctacagcatctcaggctacggagctgctggcgggaaaggcgggaagaacaccatg
atgcggtcccacggtgtgtctgtgctgggcatcttcaacctggagaagggtgacacgctg
tatatcctggtcggacaacagggggaagacgcctgtcccagcacaaaccggttaatccag
aaagtctgcattggagagaacaacgtgatagaagaagaaatccgcgtgaacaggagtgtg
catgagtgggcaggagggggcggaggagggggcggagccacctacgtatttaagatgaag
gatggcgttccagtgcccctgatcattgcagctggcggtggcggcagggcctacggggcc
aagacagacacattccacccagagagactggaaaataactcctcggttctggggctgaat
ggcaattccggagccgcaggtggtggaggtggctggaatgataacacttccttgctctgg
tctggaaaatctttgctggagggtgccaccggaggacattcctgcccccaggccatgaag
aagtgggggtgggagacaagagggggtttcggagggggtggaggggggtgctcctcaggt
ggaggaggcggaggatatataggcggcaacgcggcctcaaacaatgaccccgagatggac
ggggaggacggggtttccttcatcagtccactgggcatcctgtacaccccagctttaaaa
gtgatggagggccatggggaagtgaatattaagcattacctaaactgcagccactgtgag
gtagatgagtgccacatggaccccgagagccacaaggtcatctgcttctgtgaccatggg
acagtgctggctgaggatggcgtctcctgcattgtgtcccccacacctgagccccacctg
ccgctctcgctggtcctgtctgtcgtgacctcagcccttgtggcggccctggtcttggct
ttctccggcatcatgattgtgtaccgccggaagcaccaggagctgcgagccatgcagatg
gagcttcagagccctgagtacaagctaagcaagctttgcacctcgaccatcatgactgac
tacaaccccaactactgctttgccggcaagacctcctccatcagtgacctgaaggaggtg
cctcggaagaacatcaccctcatccggggtctgggccatggtgcgtttggggaggtgtat
gaaggtcaggtgtctggagtgcccagtgacccaagccccctgcaagtagctgtaaagacg
ctgcctgaggtgtgttctgaacaggatgaactggatttcctcatggaagccttgattatc
agcaaattcaaccaccagaacatcgtgcgctgtattggggtgagtctgcaagccctgccc
cgatttatcctgctggagctcatggcgggaggagacctcaagtccttcctccgggagacc
cgtcctcgcccgaaccagccctcctccctggccatgctggaccttctgcacgtggctcgg
gacatcgcctgtggctgtcagtatttggaggaaaatcacttcatccaccgggacattgct
gccaggaactgcctcttgacgtgtccaggccctggccgagtggccaagatcggagacttt
ggaatggcccgagacatctacagagcgagctactaccgaaagggaggctgtgcgatgctg
ccggtcaaatggatgcctccagaagccttcatggaaggaatatttacttctaaaacagac
acgtggtcctttggagtgctgctgtgggaaatattttctcttggatacatgccataccct
agcaaaagcaaccaggaagttctggagttcgtcaccagcggaggacggatggacccacct
aagaactgtcctgggcccgtataccggataatgacccagtgctggcaacatcagcctgaa
gataggcccaactttgccataattttggagaggattgaatactgcacccaggacccagac
gtgatcaacaccgctttgcccatagagtatggcccactcgtggaggaggaagaaaaggtg
cccatgaggccccaagacccggagggtattcctcctctcctagtctcccctccacaagct
aaacgggaggaagggcaggatccagctgccccgccccctctgccttccacctcctccggc
aaagcctccaagaaacccacggccgcagagctctctgttcgcgtcaccagagggcccgcc
gtggaagggggacacgttaatatggcgttctctcagtccaacccgccatcagagctacac
aaagtccagggatccagaaacaaacccaccagcctatggaacccaacttatggctcatgg
tttacagagaaacccaccaaaaagaacaatcctccggcaaagaaggagcaccatgagaga
ggaaacctgggacgtgagggaagctgtaccgtcccaccgaacgttgcaactggcagactt
ccgggcgcctctctgctcctagaaccgtcctcgctgactgccaacatgaaggaagtgcct
ctgttcaggctacgtcacttcccgtgtggaaatgtcaactatggctaccagcaacagggc
ttacctttagaggccaccactgcccctggaaccagtcattacgaggacaccattctgaaa
aaccagcctgggccctga
Felis catus (domestic cat): 101094586
Help
Entry
101094586 CDS
T02385
Symbol
EML4
Name
(RefSeq) echinoderm microtubule-associated protein-like 4 isoform X1
KO
K15420
echinoderm microtubule-associated protein-like 4
Organism
fca
Felis catus (domestic cat)
Pathway
fca05200
Pathways in cancer
fca05223
Non-small cell lung cancer
fca05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101094586 (EML4)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
101094586 (EML4)
09162 Cancer: specific types
05223 Non-small cell lung cancer
101094586 (EML4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
fca04812
]
101094586 (EML4)
Cytoskeleton proteins [BR:
fca04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EMAP
101094586 (EML4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
WD40
HELP
ANAPC4_WD40
SlyX
PKcGMP_CC
Motif
Other DBs
NCBI-GeneID:
101094586
NCBI-ProteinID:
XP_019683192
Ensembl:
ENSFCAG00000015377
LinkDB
All DBs
Position
A3:complement(108239726..108401496)
Genome browser
AA seq
1012 aa
AA seq
DB search
MEDSLPGLASVCVSSTLTNFCTDDSISAASTSDVQDRLSALELRVQQQEDEITVLKAALA
DVLRRLAISEDHVASVKKSVPSKAMKIFKGQPGLREAISMSCITNGSGANRKPSHTSSVA
IARKETLSSAAKSGTEKKKEKPQGQREKKEESHSNDQSPQIRASPSPQPSSQPLQIHRQT
QESKNSTPTKSIKRPLTTEKSHNSWENSDESRNKLLRAVSTSKLISKVIKNTDKHKDVII
NQAKMSTREKSNQEGEYVKMFMRGRPITMFIPSDVENYDDIRTELPPEKLKLEWVYGYRG
KDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCLAIHPDKIRIATGQI
AGVDKDGRPLQPHVRVWDSVSLSTLQIIGLGTFERGVGCLDFSKADSGVHLCVIDDSNEH
MLTVWDWQKKSKGAEIKTTNEVVLAVEFHPTDANTIITCGKSHIFFWTWSGNSLTRKQGI
FGKYEKPKFVQCLAFLGNGDVLTGDSGGVILIWSKTTVEPTPGKGPKGVYQISKQIKAHD
GSVFTLCQMRNGMLLTGGGKDRKIILWDHDLNPEREIEVPDQYGTIRAVAEGKADQFLVG
TSRNFILRGTFNDGFQIEVQGHTDELWGLATHPFKDLLLTCAQDRQVCMWNSVEHRLEWT
RLVDEPGHCADFHPSGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGTL
LAVGSHDNFIYLYVVSENGRKYSRYGKCTGHSSYITHLDWSPDNKYIMSNSGDYEILYWD
IPSGCKLIRNRSDCKDIDWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIAVADD
FCKVHLFQYPCSKAKAPSHKYSAHSSHVTNVSFTHSDSHLISTGGKDMSIIQWKLVEKLS
LPQNEIVADGTLTKAPISSIESVMQSDTPTLPPSQPLNEAAEDESRISNSPTLLENSLEQ
TMEPSEDHIEEQSEGGSEDLGEPIFEEPSSEISKEQSEPVLTEDRQGSPPLS
NT seq
3039 nt
NT seq
+upstream
nt +downstream
nt
atggaagacagcttgcctggtctcgcttcagtgtgtgtttcctctacacttacgaacttc
tgcactgatgatagtatttctgctgcaagtacttccgacgttcaagatcgcctctcagct
cttgagttacgagttcaacaacaagaagatgaaatcactgtgctaaaggcagctttggct
gatgttttgaggcgtcttgcaatctccgaagatcatgtagcctcagtgaaaaaatcagtt
ccaagtaaagccatgaagattttcaaaggccagccaggccttcgagaagctatttctatg
tcctgtataaccaacgggagtggtgcaaacagaaagccaagccacaccagctctgtcgca
attgcaaggaaagaaactctttcatctgctgctaaaagtggtacagaaaaaaagaaagaa
aaaccacaaggacagagagaaaaaaaagaggaatctcattctaatgatcaaagtccacaa
attcgagcatcaccttctccccagccctcttcacagcctctccaaatacacagacaaact
caagaaagcaagaattctactcccaccaaaagcataaaacgaccactgacaactgaaaag
tcacataattcatgggaaaattcagatgagagtcgtaataaattattgagagcagtttca
acatcaaaattaatatcaaaagttataaaaaatacagataagcataaagatgtcatcatc
aaccaagcaaaaatgtcaacccgtgaaaaaagcaaccaagaaggagaatatgttaaaatg
tttatgcgaggtcggccaattacaatgttcattccttctgatgttgaaaactatgacgac
atcagaacagaactgcctcctgagaagctgaaactggagtgggtatatggttaccgagga
aaggactgccgtgctaatgtttaccttcttcctaccggagaaatagtgtatttcatagca
tcagtagtagtactgtttaattatgaggagagaactcagcgacactacctgggtcacaca
gactgtgtgaaatgccttgctatacatcctgacaaaattaggatcgcaactggacagatt
gctggagtggataaagatggaaggcctctgcaaccccatgtcagagtgtgggattcagtt
agtttatccactctgcaaattattggacttgggacctttgagcgtggagtaggatgcctg
gatttttcaaaagcagattcaggtgttcatttatgtgttattgatgactccaatgagcat
atgcttactgtttgggattggcagaaaaaatcaaagggagcagaaataaagacaacaaat
gaagttgttttggctgtggaattccatccaacagacgcaaataccatcataacatgtggt
aaatctcatatttttttctggacctggagtggtaattcactaacaagaaaacagggaatt
tttgggaaatatgaaaaaccaaaatttgtgcagtgtttagcattcttgggaaacggagat
gttcttactggtgactcaggtggagtcatacttatatggagcaaaactactgtagaaccg
acaccagggaaagggcctaaaggtgtttatcagatcagcaaacaaatcaaagctcatgat
gggagtgtgttcacactttgtcagatgagaaatggaatgttattaactggaggagggaaa
gaccgaaaaataattctgtgggatcatgatctgaatcctgaaagagaaatagaggttcct
gatcagtatggaacaatcagagctgtagcagaaggaaaggcagatcaatttttagtaggc
acatcacgaaacttcattttacggggaacatttaatgatggcttccaaatagaagtacag
ggtcatacagatgagctttggggtcttgccacacatccctttaaagatttgctcttgaca
tgtgctcaggacagacaggtgtgcatgtggaactcagtagaacacaggctggaatggacc
aggcttgtagatgaaccaggacactgtgcagattttcatccaagtggcacagtggtggcc
ataggaacgcactcaggcaggtggtttgttctggatgcagaaaccagagatctagtttct
atccacacagatgggaatgaacagctctctgtgatgcgctactcagtagatggcaccctc
ctggctgtaggatctcatgacaacttcatttacctctatgtagtctcagaaaatggaaga
aaatatagcagatatggaaagtgcactggacattccagctatatcacacaccttgactgg
tccccagacaataaatatataatgtctaactcaggagactatgagatattgtactgggac
attccaagtggctgcaaactaatcaggaatcgatcagattgtaaggacatcgattggacg
acatatacctgcgtcctaggctttcaagtctttggtgtctggccagaaggatccgatggg
acagatatcaatgcactggtgcgatcccacaataggaaggtgatcgctgttgctgacgac
ttctgcaaagtccatctgtttcaatatccctgctccaaagcaaaggctcccagtcacaag
tacagcgcccacagcagccatgtcaccaatgtcagttttacacacagtgacagtcacctg
atttcaactggtggaaaagacatgagcatcattcagtggaaacttgtagaaaagttatct
ttgcctcaaaatgagatcgtagccgatggtactctaaccaaagcccccatctcttccatt
gaaagtgtcatgcagtctgatactcccacactgcctccttcccagcccttaaatgaggca
gctgaagacgaaagtagaataagcaattctcccacacttctggagaacagcctggaacag
accatggagcccagcgaagaccacatcgaggaacagagtgaagggggcagcgaggacctc
ggtgagcctatttttgaggagccatccagtgagataagcaaggagcagagtgagcccgtt
cttaccgaggaccggcaaggctccccacccctgtcttaa
DBGET
integrated database retrieval system
