Felis catus (domestic cat): 101091691
Help
Entry
101091691 CDS
T02385
Symbol
PTK2B
Name
(RefSeq) protein-tyrosine kinase 2-beta isoform X2
KO
K05871
focal adhesion kinase 2 [EC:
2.7.10.2
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca04020
Calcium signaling pathway
fca04062
Chemokine signaling pathway
fca04072
Phospholipase D signaling pathway
fca04650
Natural killer cell mediated cytotoxicity
fca04670
Leukocyte transendothelial migration
fca04912
GnRH signaling pathway
fca05135
Yersinia infection
fca05161
Hepatitis B
fca05163
Human cytomegalovirus infection
fca05170
Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
101091691 (PTK2B)
04072 Phospholipase D signaling pathway
101091691 (PTK2B)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
101091691 (PTK2B)
04670 Leukocyte transendothelial migration
101091691 (PTK2B)
04062 Chemokine signaling pathway
101091691 (PTK2B)
09152 Endocrine system
04912 GnRH signaling pathway
101091691 (PTK2B)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101091691 (PTK2B)
05161 Hepatitis B
101091691 (PTK2B)
05163 Human cytomegalovirus infection
101091691 (PTK2B)
09171 Infectious disease: bacterial
05135 Yersinia infection
101091691 (PTK2B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101091691 (PTK2B)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101091691 (PTK2B)
Protein kinases [BR:
fca01001
]
Non-receptor tyrosine kinases
FAK family
101091691 (PTK2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
FERM_N_2
Pkinase
FERM_M
Kinase-like
FERM_F2
RNA_pol_Rpb2_6
Motif
Other DBs
NCBI-GeneID:
101091691
NCBI-ProteinID:
XP_011279839
Ensembl:
ENSFCAG00000014420
UniProt:
A0A337ST84
LinkDB
All DBs
Position
B1:50782283..50908398
Genome browser
AA seq
1009 aa
AA seq
DB search
MSGVSEPLSRVKVGTLRRPEGPPEPMVVVPVDVEKEDVRILKVCFYSNSFNTGKNFKLVK
CTVQTEIQEVIASILLSGRIGPNIQLGECYGLRLKHMKSDEIHWLHPQMTVGEVQEKYEC
LHMEAEWRYDLQIRYLPEDFMESLKEDRTTLLYFYQQLRNDYMQRYASKVSEGMALQLGC
LELRRFFKDMPHNALDKKSNFEFLEKEVGLDLFFPKQMQENLKPKQFRKMIQQTFQQYAS
LREEECVMKFFNTLAGFANIDQETYRCELIQGWNITVDLVIGPKGIRQLTSQDAKPTCLA
EFKQIKSIRCLPLEEGQAVLQLGIEGAPQSLSIKTSSLAEAENMADLVDGYCRLQGEHKG
SLIIHPKKDGEKRNSLPQIPVLNLEAQRPHLSESCSIESDIYAEIPDETLRRPGGPQYGV
TRDDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLDNKEKFLSEAVIMKN
LDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLERNKNSLKVLTLVLYSLQICKAMAYL
ESINCVHRDIAVRNILVASPECVKLGDFGLSRYIEDEEYYKASVTRLPIKWMSPESINFR
RFTTASDVWMFAVCMWEILSFGKQPFFWLENKDVIGVLEKGDRLPKPDLCPPVLYTLMTR
CWDYDPSERPRFTELVCNLSDIYQMEKDIAIEQERNARYRPPKILEPTAYQEPPPKPSRP
KYRPPPQTNLLAPKLQFQVPEGLCASSPTLTSPMEYPSPVNSLHTPPLHRHNVFKRHSMR
EEDFIRPSSREEAQQLWEAERLKMRQILEKQQKQMVEDYQWLRQEEKSLDPMVYMNDKSP
LTPEKEAGYTEFTGPPQKPPRLGAQSIQPTANLDRTDDLVYLNVMELVRAVLDLKNELCQ
LPPEGYVVVVKNVGLTLRKLIGSVDDLLPSLPSSSRTEIEGTQKLLNKDLAELINKMRLA
QQNAVTSLSEECKRQMLTASHTLAVDAKNLLDAVDQAKVLANLAHPPAE
NT seq
3030 nt
NT seq
+upstream
nt +downstream
nt
atgtctggggtgtccgagcccctgagccgagtgaaggtgggcacgttacgtcggcctgaa
ggccccccagagcccatggtggtggtgccagtagatgtggaaaaggaagacgtgcggatc
ctcaaggtgtgcttctatagtaacagcttcaacaccgggaagaacttcaagttggttaaa
tgcactgtgcagacagagatccaggaggtcattgcctccattctgctgagcggacggata
gggcccaacatccagctgggtgagtgctatggcctgaggctgaagcacatgaagtcggat
gagatccactggctacacccgcagatgacagtgggtgaggttcaggaaaagtacgagtgt
ctgcacatggaggctgaatggaggtatgacctccaaatccgctacttaccagaggacttc
atggaaagcctaaaagaagacaggacaacgctactttatttttaccaacagctacggaat
gactacatgcaacgctatgccagcaaggtcagcgagggcatggccctgcagctgggctgc
ctggagctcaggcggttcttcaaggacatgccccacaatgcacttgacaaaaagtccaac
ttcgagttcctggagaaagaagtaggactggacctgtttttcccaaagcagatgcaggag
aacttaaagcccaagcagttccggaagatgatccagcagaccttccagcagtacgcctcg
ctcagggaggaggagtgcgtcatgaagttcttcaacaccctcgcgggctttgccaacatc
gaccaggagacctatcgctgtgaactcattcaaggatggaacattactgtggacctggtc
attggcccgaagggcatccgccagctgacaagtcaagatgcaaagcccacctgcctagct
gaattcaagcagatcaagtccatcaggtgcctcccactggaggaaggccaggcagtacta
cagttgggcattgaaggtgccccccagtctttgtccatcaaaacctcctctctggcagag
gccgagaacatggctgacctggtggatggttactgccggcttcaaggggagcacaaaggc
tctctcatcattcatcccaagaaagatggtgagaagcggaacagcctgccccagatcccc
gtactaaacctggaggcgcagcggccccatctctcagagagctgcagcatagaatcagac
atctatgcagagattcccgatgagaccctgcgaaggcccggaggcccacagtatggcgtc
acacgggatgatgtagtcctgaatcggattcttggtgaaggcttttttggggaggtctac
gaaggtgtctacacaaatcacaaaggggagaaaatcaacgtagctgtaaaaacctgcaag
aaagactgcactctggacaacaaggagaagttcttgagtgaggcagtgatcatgaagaat
cttgaccaccctcatattgtgaagctgatcggcatcattgaagaggaacccacctggatc
atcatggaattgtatccctatggtgagctgggccactacctagagcgaaacaagaactcc
ctgaaggtgctcactctcgtcttgtactccctgcagatttgcaaggccatggcctatctg
gagagcatcaactgtgtccacagggacatcgccgtgcgaaacatcctggtggcctcccct
gagtgtgtgaagctgggggactttggcctttcccggtacattgaggatgaggaatattac
aaagcctctgtgactcgtcttccgatcaagtggatgtcccctgagtccatcaatttccgc
cgctttacgacagccagtgacgtctggatgtttgctgtatgcatgtgggagatcctgagc
tttggcaagcagcccttcttctggctggagaacaaggacgtcatcggggtgctcgagaag
ggggaccggctacccaagcccgacctctgcccacctgttctctacaccctcatgactcgc
tgctgggactacgaccccagtgagcggccccgcttcactgagctcgtgtgcaacctcagt
gacatttatcagatggagaaggacatcgctatagagcaggaaaggaatgctcgttaccga
cctcccaaaatcttggagcccacagcctaccaggaacccccacccaagcccagccggccc
aagtatagaccccctccacaaaccaaccttctggctcccaagctgcagttccaggtccct
gagggtctgtgtgccagctcacctacgctcaccagccctatggagtatccatctcctgta
aactcgctgcacaccccacctctccatcggcacaatgtcttcaagcgccacagcatgcgg
gaggaggacttcatccgacccagcagccgagaagaggcccagcagctatgggaggccgag
aggctcaagatgaggcagatcctggagaaacagcagaagcagatggtggaagattaccag
tggctgaggcaggaggagaaatccttggaccccatggtgtacatgaacgataagtccccg
ctgaccccagagaaggaggccggctatacggagttcacgggccccccacagaagccaccg
cggctgggtgctcagtccatccagcccacagccaacctggaccggaccgacgacctggtg
tacctcaatgtcatggagctcgtgcgggctgtgctggatctcaagaacgagctctgtcag
ctgcctcccgagggctatgtggtggtggtgaagaacgtgggcttgaccctgcggaagctt
attgggagcgtggatgatctcctgccctccttgccgtcatcctcccggaccgagattgag
gggacccagaagctgctcaacaaggacctggcggagctcatcaataagatgcgcctggcc
cagcaaaacgccgtgacctccctgagtgaggagtgcaagcggcagatgctcacagcctcc
cacaccctggccgtggacgccaagaacctgctcgatgccgtagaccaggccaaggttctg
gccaatctggcccacccgcctgcagagtga
Felis catus (domestic cat): 101095952
Help
Entry
101095952 CDS
T02385
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
fca
Felis catus (domestic cat)
Pathway
fca01522
Endocrine resistance
fca04012
ErbB signaling pathway
fca04062
Chemokine signaling pathway
fca04151
PI3K-Akt signaling pathway
fca04360
Axon guidance
fca04370
VEGF signaling pathway
fca04510
Focal adhesion
fca04670
Leukocyte transendothelial migration
fca04810
Regulation of actin cytoskeleton
fca04935
Growth hormone synthesis, secretion and action
fca05100
Bacterial invasion of epithelial cells
fca05135
Yersinia infection
fca05146
Amoebiasis
fca05163
Human cytomegalovirus infection
fca05165
Human papillomavirus infection
fca05170
Human immunodeficiency virus 1 infection
fca05200
Pathways in cancer
fca05202
Transcriptional misregulation in cancer
fca05205
Proteoglycans in cancer
fca05208
Chemical carcinogenesis - reactive oxygen species
fca05222
Small cell lung cancer
fca05417
Lipid and atherosclerosis
fca05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
fca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101095952 (PTK2)
04370 VEGF signaling pathway
101095952 (PTK2)
04151 PI3K-Akt signaling pathway
101095952 (PTK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
101095952 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101095952 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
101095952 (PTK2)
04062 Chemokine signaling pathway
101095952 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
101095952 (PTK2)
09158 Development and regeneration
04360 Axon guidance
101095952 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101095952 (PTK2)
05202 Transcriptional misregulation in cancer
101095952 (PTK2)
05205 Proteoglycans in cancer
101095952 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
101095952 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
101095952 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101095952 (PTK2)
05163 Human cytomegalovirus infection
101095952 (PTK2)
05165 Human papillomavirus infection
101095952 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
101095952 (PTK2)
05100 Bacterial invasion of epithelial cells
101095952 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
101095952 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101095952 (PTK2)
05418 Fluid shear stress and atherosclerosis
101095952 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
101095952 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
fca01001
]
101095952 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
fca01009
]
101095952 (PTK2)
Enzymes [BR:
fca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101095952 (PTK2)
Protein kinases [BR:
fca01001
]
Non-receptor tyrosine kinases
FAK family
101095952 (PTK2)
Protein phosphatases and associated proteins [BR:
fca01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101095952 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_M
FERM_F2
Kinase-like
Haspin_kinase
GIT1_C
ABC1
Motif
Other DBs
NCBI-GeneID:
101095952
NCBI-ProteinID:
XP_023104388
Ensembl:
ENSFCAG00000014619
LinkDB
All DBs
Position
F2:complement(82558844..82819663)
Genome browser
AA seq
1155 aa
AA seq
DB search
MLVELAGREALRPAGAVCMEKSGCGPFPMCWAKDYDRYIAPSKIMAAAYLDPNLNHTPNS
STKTHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCSPTHLADFNQVQTIQYSNSEDKDRKGTL
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGVRTHAVSVSGIYPDVTHSAARALTWASRSVSSLGALATSPSPLTLLSPCPTSL
LLETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMS
PENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLVGVITENPVWIIMELCT
LGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLG
DFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPF
QGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEE
KVQQEERMRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQ
VSGYPGSHGVTATAGSIYPGQASLLDQTDSWNHRPQEISMWQPNVEDSAALDLRGIGQVL
PTQLVEERLIRQQQEMEEDQRWLEKEERFLVILKPDVRLSRGSIDREDGSLQGPTGNQHI
YQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPPTANL
DRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPA
STHREIEMAQKLLNSDLGELINKMKLAQRCAMTSLQQDHKKQMLTAAHALAVDAKNLLDV
IDQARLRALGHARPR
NT seq
3468 nt
NT seq
+upstream
nt +downstream
nt
atgttggtggaactggcgggccgagaggccctgagaccagcaggtgccgtctgtatggag
aagagcggctgtggtccatttccaatgtgttgggctaaagattatgacagatacatagca
ccaagcaaaataatggcagctgcttaccttgacccaaacttgaatcacaccccgaattcg
agtaccaagacccatctgggtaccggagtggaacgttcccccggggcaatggagcgagtg
ttgaaggtctttcattattttgagaacagcagtgagccagccacttgggccagtattatc
aggcacggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgtctcagtcacctgcggtcagaggaggttcac
tggctccatttggatatgggtgtctccaatgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctatcaacaggtgaaaagtgactacatg
tcggagatagctgaccgggtggaccaggacatcgctttgaagctgggctgcctagaaata
cggcgctcgtattgggagatgcgaggcaacgcgctagagaagaagtccaactatgaggtg
ttagaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaaactgatccaacagacgtttagacagttcgccaacctgaacaga
gaagagagcattctgaaattctttgagatcctctccccagtgtaccgatttgataaagag
tgcttcaagtgtgccctcggttcaagctggattatttcagtggaactggcgatcggccca
gaagaaggaatcagttacctcacggacaagggctgcagccccacacatctggccgacttc
aatcaagtgcagaccattcagtattccaacagcgaagacaaggacaggaaaggaacgctg
cagctgaaaatcgcgggcgcccccgagcctctgacagtgacagcaccgtccctgaccatc
gccgagaatatggctgacctgatagatgggtactgccggctggtgaacggagccacgcag
tcctttatcatcaggccccagaaagaaggtgaacgggctttgccatcaataccaaagctg
gccaacagcgagaagcaaggcgtgcggacacacgcggtctccgtgtcaggcatctaccct
gacgtcactcacagtgcagccagagccctgacgtgggcttctaggtctgtgtcatcactg
ggagcattggccacctctccctcacccctcactcttttgtcaccctgcccaacctcattg
ctcctcgaaaccgacgactatgctgagattatagacgaagaagatacctacaccatgccc
tcaaaaagctatggaatagacgaagccagggactacgagatccaaagagaaagaatcgag
cttggacggtgcatcggggaaggccagtttggggacgtccaccaaggcgtctacatgagt
ccagagaatccggctttggcggtcgcaattaaaacatgtaaaaactgtacttcggacagc
gtgcgagagaaattccttcaagaagccttaacgatgcgccagtttgaccacccccacatt
gtgaagctggtcggtgtcatcacggagaaccccgtctggataatcatggagctgtgcaca
cttggagagctgaggtcgtttctgcaagtgaggaagtacagtttggatctcgcgtctttg
atcctgtatgcctatcagcttagtacagctctggcgtatctggagagcaaaagattcgtg
cacagggacattgctgctcggaatgttctggtgtcctcaaatgattgcgtaaaattagga
gacttcggattatcccggtatatggaagacagtacttactacaaagcttccaaaggaaag
ttgcctattaaatggatggctccagagtccatcaactttcgacgttttacctcagccagt
gacgtgtggatgttcggtgtgtgtatgtgggagatactgatgcatggtgtgaagccgttt
caaggagtgaagaacaatgatgtgatcggtcgaatcgagaacggggagagattaccaatg
cctccaaattgccctcccaccctctacagccttatgacgaaatgctgggcctatgacccc
agcaggcggccccggttcactgagctcaaagctcagctcagcaccatcctggaggaggag
aaggttcagcaagaagaacgaatgaggatggaatcccgaagacaggtcacagtgtcctgg
gactccggagggtccgacgaagcgccacccaagcccagcagacctggttaccccagtcca
cggtccagcgaaggattttatcccagtccccagcacatggtacagaccaatcattaccag
gtgtctggctatcctggctcacatggggtcacagccacggctggcagcatctacccgggt
caggcatctcttttggaccagacggactcatggaatcacagaccacaggagatatcgatg
tggcagcccaacgtggaggactctgcggccctggacctgcgcgggatcgggcaggtgctg
cccacccagctggtggaagagcggctgatccggcagcagcaggaaatggaggaggaccag
cgctggctcgagaaagaggagagattcctggtcatcctgaaacccgacgtgcggctctct
cgaggcagcatcgacagggaggacgggagtcttcagggcccgacgggaaaccaacacatc
tatcagcctgttggtaaaccagatcccgcagctccgccaaagaaaccgccgcggcctgga
gcccccggtcacctgggcagcctcgccagcctcagcagccccggggacagttacaacgag
ggcgtcaagccatggaggcttcagccccaggaaatcagccccccgcccactgccaacctg
gaccggtccaacgacagggtgtacgagaatgtgacgggcctggtgaaggctgtcatcgaa
atgtccagcaagatccagccagcccccccggaggagtacgttcccatggtgaaggaagtc
ggcctggccctgcggacattactggccaccgtggacgagacccttccggtcctgccagcc
agcactcaccgagagatcgagatggcccagaagctgttgaactccgacctgggcgagctc
atcaacaagatgaagctggcccagcggtgcgccatgaccagcctgcagcaggaccacaag
aagcagatgctgaccgccgcccacgccctggccgtggacgccaagaacttactcgacgtc
atcgaccaggccagactgagggcactcggacacgcgaggccgcgctga
DBGET
integrated database retrieval system
