Grus americana (Whooping crane): 129202302 Help Entry 129202302         CDS       T11359                                  Symbol OBSCN Name (RefSeq) obscurin isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism game  Grus americana (Whooping crane) Pathway game04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:game00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     129202302 (OBSCN)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:game01001]     129202302 (OBSCN)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:game04131]     129202302 (OBSCN) Enzymes [BR:game01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      129202302 (OBSCN) Protein kinases [BR:game01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    129202302 (OBSCN) Membrane trafficking [BR:game04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     129202302 (OBSCN) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  129202302 NCBI-ProteinID:  XP_054670801 LinkDB All DBs Position 2:complement(165855902..166055754) Genome browser AA seq 10370 aa AA seqDB search MDYSSFSGVPRFLTRPKAFMVSVGKDATLSCQIIGNPIPAVSWEKDKLPVQSGGRFKTTE DGDLYRLTIYDLSLEDSGQYICRAKNTIGEAFAAVSIKVGEETTVTESAPYFIQKPSSIK VTLGEDAMFKCKVQGSPPLSVNWEKDGRHLRNRADAGRFQIESAGESNALTIQCARLGDS GTYTCRAENPIGSASASAALVVETQGSSNPGSSSHFDTSCGKTASLLSHLQKRREEIRKM DVSYGALDSSSTQSYSTAEGLSGIGYGRSRDYERVAGFTTKGARNATFGALTRMCSVTEG KHAKLSCYVTGEPKPEIVWKKDNEVILEGRRHVIYEDDQENFVLKILFCKQIDNGLYTCT ASNLAGETYSSVLVTVKEPSIPFKEKLRDLEVREKESATFQCEVPVPSTETAWFKEETKL RQSKKYNIEEEGTYRRLTVQNVTADDDAVYICEMKEGSRTIAELSVQGNIIKKLPRKTAV FINDTAIFCVELDNECQNIRWLKNKEEVKPSDRISITCSGKQHTMIIRECKMEDAGEIAF LADESRTSTQFTVTTPRKPPTQPPADPVVKNKTETSVTLAWSPPKMDRPIPIDGYIVERK KLTGFTWVRCHESHVPVPEFTVSNLSEESDYQFRVSAVNAYGQSPYLEFPGSMHLEPVLA VKTPLTTVEAVPGGDALFTIDLTTTCSGTWYLNGKVLQESETYIIKRTQTTHTLIIKKVT KNDDGAEIKFVANNVDTSTKMRVKGAAVRFTNKSRDIEKVSVRLREEAKLQAELSDAEAT VKWMKDGKELKASEKYELQTVGKKHILKIHNTAAEDAGVYECICEGDKMVYQLSVKALPN FINKEKSGGVIRAIAGKQAEFVSETSEANVMVKWYKSGKEITASKKFTMEDKGKLHKLVA SAVTKEDEGIYTCKIGDDTLIFDLKVSDEPVNFVNKPKTTPEISVSPSEDLELVCEVSAV SGAVVWKKDQTEVKQDQRTTIISQGTHRKLIIKKVTQQDQGSYTCETKDDRTTFQVKVRE TEDMFTNKDKVQKEVKAALSEDATLSCEVAQEKTDVKWYKEGKLITSSKKFKVESQGKSR RLVVGQVEKKDAGEYTCEAAGQKLTFKLDVTEPEVVFTNKDKVQKEVKAALSEDATLSCE VAQEKTDVKWYKEGKLITSSKKFKVESQGKSRRLVVGQVEKKDAGEYTCEAAGQKLTFKL VVTEAEDAFINKDKVKKEVKAAPSEDATLSCEVAQEKTDVKWYKEGKLITSSKKFKVESQ GKSRRLVVGQVEKKDAGEYTCEAAGQKLTFKLDVTEPEVVFANKDKVQKEVKAALSEDAT LSCEVAQEKTDVKWYKEGKLITSSKKFKVESQGKSRRLVVGQVEKKDAGEYTCEAAGQKL TFKIDVTDDVFEHKDKVQKEVKAVLKENTTLSCEVAQEKTDVKWYKEGKLITSSKKFKVE SQGKSRRLVVGQVEKKDAGEYTCEAAGQKLTFKLDVTEAEDAFINKEKVQKEVKAAPSED ATLSCEVAQEKTDVKWYKEGKLITSSKKFKVESQGKSRRLVVGQVEKKDAGEYTCEAAGQ KLAFKLDVTEPEVVFTNKDKVQKEVKAALSEDATLSCEVAQEKTDVKWYKEGKLITSSKK FKVESQGKSRRLVVGQVEKKDAGEYTCEAAGQKLAFKLDVTEPEVVFTNKDKVQKEVKAA LSEDATLSCEVAQEKTDVKWYKEGKLITSSKKFKVESQGKSRRLVVGQVEKKDAGEYTCE AAGQKLTFKLDVSEPEVVFTNKDKVQKEVKAALSEDATLSCEVAQEKTNVKWYKEGKLIT SSKKFKVESQGKSRRLVVGQVEKKDAGEYTCEAAGQKLTFKLDVTEPKPAFINEEKVQKE VNAVLTESATLSCEVAQDATEVKWYKDGRLLISSRKFKVETVGKTRRLVIEQLEKKDAGE YICEAAGQKLTFKLKPTEPEAKFENKVVQKEPLIVQEYESITLSTSVTPETAAVKWFKDG TEIKASKKYEIKSEGASRTLTVNLAESTDTAVYTCQTKSDKQEFKVQVKEIPVKFAKKLE AVNAEIGGSVSLTCDVSHAKGKVVWCRNGVQIKPSKRFQIHEEGVKRTLTITGIRAEDEG EYSCESRDDKSSVTITPKPPRVVKFVTSLNSVVSEEGKEAVFKCTVSPSDAVVTWFRNGV KIEASEKYVISQKDTNHSLTITDLTLKDAAEISANAEGVESTANLRVREASISFKKKLEP RTVEERDTVTLEVELTKPAEVKWMRNSIVLKPSEKIEIKAEGTKHTLVVKDISFADRGFY CCESPDDKTQAKINVEMRQIKLVKGLQALEVSEKGTVTFEVEVSHEDVEGTWQKDGIRLK PSPNISIGVLGKKRSLTLSSVSLEDAGLISFKADGIHTSGRLTVTELPVRISKPLTDVSV TQKDKVTFECELSRSNVDVKWFKDGKELQQSKKVGIISQGNKRSLIIHKCEYEDQGTYTC EAAEDKTSATLKVHARDIKIVKPLEDVEVNEYESASFVCEISHDEVQTQWYKNDNKLKAA DNIRMRQDGKTYSLTYMRVQVEDAAEIKFVAEKAESRAQLTVKELPVKIVKPLRDKIALE KHRGFLECQVSRANAKVRWYKKDREIHPSDKYEIVSDGVYRKLIINDADYEDEDTYTCDA FDDKSSANFFVEEQSISIVKELCDEDVTEPEEAKFECEISIPSVKPPKWSLHGEILQAGR NIIMQQEGTIHRLTILKTSADMTGTIQFSIGKSKSTANLLVRDYHIQITRKMEDKTALER HSVILSCDFRPSPKVVKWFKDHAPIEPSEKYKIRREQHSAELKILKVKPEDAGVYKCRAG NAETEATLTVEARNVEILKHLQDVEIEEESSAVFSCELSHDDEDVEWFLNGTLLYTNNFN DIRNVGNCYTLTMKQVKPEDAGTVTMKSDKVSESVRLKVIEKPAVFMKSLDDVFGEERGV IKLECEVSKEKVKPVWKKDGVTLTSGNKYEQIQSGKTLCLLIHDLEKTDAGLYTCDIDTD VAKSKVSIQELNIGITKRLKNTEIQEGEDCTFECILSHESIDDFNWTLNGSKVESGGRFK ASNMGRKYMLNIKSVIPDDAGEVIFTARGLTSKASLVVKEKPTEVTKQLEDKTSAVGQDI SLSCELSKPDVSIRWYKDGKAIRKSQKYDLRQEGTRAILIIHASTIKDSGEYTCETEFSK TKARITVQEKPNYFVKELSDLKADENGTAVFMCQSEKAAPSVVWRKGIAELRASRKYEIT QKGQVLQLTINNLEKSDSDTYTCDIGDAQSRAKLVVQGQKVLITEDLEDVTVLEGESAMF KCRISPVDYSKVQWFLDKTPLHTNELNEIQSQPGGYHLLTLKKLSLKDSGVITFEAGDKK TSASLVVKEKPCIFTKELADTEVTEGEDVILHCETSKSDSPVKWCKDGKSLRNSSKYNIS RSGFEAKLVIHRAEERDSGRYECEAGAAKSSAVITVKEIPVLFKQELQNEEAKEGKQVKL TCELSKPDMPVKWMKGDAVLYASEKYEFKQCGTVAELIIRDVTSIDAGDYTCSTGEQKTT ARVKVNAVPVLFKQALENTEMEEGKSVSLRCELTKADATVVWKKGEATLQASAKYEMKQK GTVAELVIHNAEPEDAGRYICDTGDQQTTAQVKIHAVSVLIKEELKSVEAVEGGTATLRC QLSREAPVEWRKGHALLRPSNKYRMRQEGMVAELLIHDLDPKDAGDYTCVVGDQKTTAAL SVNALPVRFKKELKNEEGTESGTATLQCELSQAVGSVEWRKDGKVLMPNGKYKMRREGRF AELVIQDLDLADAGNYTCVCGDQKTTAALRVNALPILFQEEMLNKEATEGEAVTLHCKLS KSAPVEWRKGNMVLKPSEKYKIGQEGPFAELMIRDLDLADAGDYSCVCGDQQTTAALTVN VLPALFTKELTDEEATEGKSVSLHCELNKAAASVEWKKGFKTLKSSDKYKMKREGVVAEL TIQNLDTTDAGNYSCVCGDQQTMAVLTVHALPAFFKEGLKNREATDGATATLHCELSKVG VPVEWKKGDKTLKPSDKYRMRQEGTAAELLIRDLEVEDTGEYTCACGDQKTSAVLTVHAL PALFKKELVNMEAAENGTAVLQCELTKPTPVEWRKGQKVLKPSEKYKMRLKDAVAELTIH SLEEQDAGDYTCVCGDKMTTASLTVHALPPHFKKELKNVEATENGTATFCCELNKPAAAV EWRRGGRALETNDKFTVRCEGTIAELVIRDLDLTDAGDYTCCYGDQETTAALKVNALPAH FKKEMKNEEATEGGTATLQCELSRTASVEWKKKHKVLKSSEKYTMRQEGTTAQLLIHALE VKDAGEYTCVCGEEKTTAALAVHALPALFKEELRNEEAMEGEVVTLRCELTKTASVEWKK GHTVLKPSEKYKMRQKDVTAELVIHNLDETDAGDYTCVCGDKQSTASLAVHALPARIKES LKDEEVTEGQAATLRCELTKVAQVQWRKGSSLLKVSDKYKMRQEGTVMKLLIHDVELKDA GEYTCMCGEQETTAALKVHALPALFKEELKDLQAMESQTATLRCELTKAAAVSWKKGNKI LRASEKYIMRQDNALAELEICDLELQDAGDYTCVCGDQHTTASLTVNALPVLFKEELKNE EVQEGASVSLRCELTKAAPVQWKIGSKVLKASDKYQMRQPGTTAELFIHDLEVKDAGDYT CVCGDQKTTATLTVHALPPLFKEELRNKEAEEGGEVALHCELSKAAPVEWWKDQRILRAS EKYKMRQEGTKAELVIHEIAEEDAGDYTCVCGEHQTTAVLTVQAVPSFFREEMTSKEAVE GGTVTLCCELSKASAHVQWKKGHRVLTPDKKYSMRQEDCVVELVVHELDLNDTGDYTCVC GDKSTTAALTVHALPPEFKKDLKDLEAVESGTAALHCELTKPAAVEWKKGQEVLKASSKY KISQDGAVAKLIIHELDVEDTGDYTCVCGDQQTTATLTVNALPALFKQDLQNTEAKEGGT ATLRCELTKPNAPVEWRKGDTTLYPGLKYEVKQQGCTAELVIYDLELDDSGKYTCDSGDQ QTTAVVTVHALPVTFKQPLQNKESEEGSTATFCCELSKPNAAVEWRKGGVGLQPSQKYEM RQRECLVELLIHNLKLDDTGEYSCDTGDQETKASLNVKALPVLFKKELKDEEAEEGAAVK FQCELTKDNATVEWRKGTMELFPCAKYEIKLSGRTAELVIHNVEPEDASDYTCDTGDQQS TAVLTVNAIKPRLKQQLKNEEVEVGGMARLRCEISISKAEVEWRKDGVVLHSSSKYEMWQ DGTLRELRVHHLEPSDAGEYSCKAGDETSSAKLTVKEPDVTIVSGLKDMVVFEGDDVTFQ CQVSHENARDVEWKLQDVALQNNEMNEISVEKGKIHTLMLRKVTEQDIGTITFRVGPHTS TAELTVKVPPPVFKEKLQSTELQEEETAILRCEVSQANATVKWKKGTQVISPSSKYEIRQ EGTIHTLKIYHLKPEDAGKYTCDNGNEQTTATLTVKALPVIFTQPLQNQQAEEGGTITLS CEISKSNVAVQWKKAGTVLRPSEKYKMHQAGSMAELTIHNLSEADAGEYVCDTGDQQTTA AVFVKESAATIVETLKDVTSYEGEDAVFECRLSRETTQDAQWFLGDVPLQSNEMNEIRVQ GTRHTLILRKVTLEDCGPISFKVGQHTSAAQLTVQVAPVTFVKTLHSLELQEGGTAHLSC EVSKPDVPVEWKKGTSVIHSTQKCSIKQEGNVHTLVIHDLNRADSGEYSCHTADGKTTAR LEVKALPVLFKHWLKNEEVEEGCTAMLHCELTKPNASVEWRKGDTVLQPSDKYEIRQEGT RVELFIYDAEAQDAGDYTCDSGDQQTTASLQVKVLPVLFNKELKNVESEEGGTAVLHCEI SKPDAPVEWRKGGVVIQPSDKYEMKLKGSIAELIIHGVEADDCGDYTCSTGYEITTGSVY VQEEEAVIVSGLTNTDVFVGESATFTCELSHPGVKNVQWWLDGSPLHNNFVTEISEQDGM IHTLTLNDVACHDSGTVTFRAGSLISSAKLLVKDPTIEVVSPMQDITVDEDGTAEFICQY SRPVHAIWKKNDQEIHADGQRVIIDQDWNVSMLKIKPTVPEDTGIYSCEAEGIKVMAALD VQAKNSIVQGLENVEAVEGGEALFECYLSKPECYNYNWLIDDEPAKTTENTEMVYFENGR RHLLLLKNLTPQDSCRVTFMCSDAVTSAFLTVKGWRLQILQPLTDVEVSLGEKATFSCVL SEAVPLTEVAWYNNDVEIQSDEDWEVQADGNKYKLILKKAQPHHSGEVTFASREAIASAK LSVIAHPEPPEEPEVLSKNSHSVTLSWYKPLSDGGCDILGYNVEKKIPGIGWQSCNKGII QNTEFMVDDLTPGEPYRFRVSAINKVGSSEPVHFPQMVRLEAPVTVTHPLVGGSVSEGEV ARLECKLSGETEEKVTWFKGKEEIQAGGRYEIISDGKKQILIIHAFKPEDQDTYTCMVSP EVKSVASLCLEVPTVTMLKEIASEAPSATQPEELVDGHVQPSLPPEAAQEGDLHLLWEAL AKKRRMSREPTLDSISEVPEEDEKLQKLRKEEAEMSHYYSEEYSTCDELARTGEADFSFT SSDDESRAGTPSLVNYLKKAGKASVSVTSKAQSISTGKLWKQWEKSSVETVVAAPAAKPA KPEISDLDDPSMNKAAVKIQAAFKGYKVRKEIKQQECPVFTETFKDFSGEPGSTLHLECV AHSKTDMKVRWLKDGEELSDGRYYHIDNYSDGTCSLIITGLDMKDAGKYTCEASNKFGKV SHSAKVVVGTQEPQAVHKEKQVKQSTDSETESSSGSELDDAFRKAGRRLHRLFRAKISTE ISDVEEELFVSADEGDIEVVDHQTYREDDQYIYIKFEILSEAKTAATRFREMFGALGIPV EIDILEQGPKKMELRIGKATPPTHGKFVPPVVRPPPPLLTSDTAPMFMTELQNQEVQDGY PVSFDCIVVGKPLPTVRWFKDGKAIEENDHYMINEDQEGCHQLIITAVVPTDMGVYRCLA ENNMGVASTKAELRVDLTSTDYETAADATETSSYYSAKEYISSREQEESTTEEEQLPQIL DELHDIHVAPGASLAKFHLKVKGYPQPRLYWFKNGQPLKASDRILKTDKQEFHSLEIRDV TKADAGQYSIFVINSAGSAYSSARLVVKDPDEKEEPSETDSHEQLIPPRFLERFTNKKVK KDASITLSVKVEGHPPPTITWLKEESQEDILWIKPDTPGYKLASSNMHHSLILLDVKKKY SGAYTCIATNKAGQSICTATLEVADVKEAEVLTQERVMVSEAIMTTLGAIQPSETREGDL EAGREGVPKSPISLADVGSEEFFQKLTSRISEMVSAKISQATLRVPGAESDDESKTPSAS PRHGRSRPSSIAQESSSESEDGDSRGEIFDVYMVTADYVPAAPDRETITLKEGQYVEVLD SAHPLKWLVRTKPTKSSPSRQGWVSPAYLDKKLKLSPEWGTTEAPEFPGEFVSEDEYKRK LSVLMQELLISEEDYIQDLQFLQTHHLKYTETCPNVPGAVASQRSTIFRNIDDIARFHSS VFLRGLQKCDTDDDVAMCFIKHEAEFNKYIQYLVGRVQAESIVVSKAVQDFYKRYTDEIL TNEDPSQPLIPPLQHYLEKPINRIQQYQTIIKELIRNKARSSQNCTLLEQAYAIVSALTR RAENNLHVSLIENYPGTLESLGEPIRQGHFIVWEGAPGARMAWKGHKRHVFLFKNYIVIC KPKRDTKTDTYSYIFKNIMKLNNIDVNDLVEGDDRAFEIWHEREDLVRKYLLQARTVNIK NSWLKDICGIQQRISEPVWIPPDFEEELADCTAELGETVKLACKVTGAPKPSVSWYKDGK PVEVDPHHIIIEDPDGSCTLILDNLTGVDSGQYICFASSPAGNASTLGKILVQVPPRFVN KVRNAYFVEGEDTQFTCTIEGAPRPQIRWYKDGLLLKDTSKYQTFSEPRSGIIVLVVKNP SNEDMGHYECELVNRLGSAKSGAELYHHSAAALTQERRGDQAITIEGMTSPQSKVETTVQ ASLQRADKEIKTALKKLVDSASLLVTLPPSMQGGAGGLGLPGSIPSEHSERAAGPSVIVQ EASTQTQTAGGHDKAQRQIPAEEPSVPKSSPGLSRDETAAGDERTQERTVPITRTSPAAG AGDWYRREGDVVWDVHSEVYIETTERTRVYKTEEKTPTSPPYMQVTIEDVQVNSGERAKF QAVIEGTPQPTVLWFKGTSLLTDSTRLHQGKEGTTYFLVVDNAVSEDGGVYTCVAKNAGG EVLCKAELIVHEAKKDQAAKKVATRRKLHSLYEVKQEIGRGCFSFVKRVVHKGNRVSCAA KFIPLRSKTKARAHQERDILASLSHDRITRLLDQFETRKTLILILELCSSEELLDRLFKK SVVTEAEVKLYIKQILEGIKYLHDNNVLHLDIKPLNILMVYPEREDLKLCDFGFAQKITP FEPQFSKYGSPEFVAPEIVSRSPVSKATDIWAVGVITYLSLTCKSPFAGENDRGTLLNIQ NGEISWTIPDFVHLSEDAKDFMKGILQQHPEARPSALDCLSHKWFMHNLPLEAAHFINTK QLKFIVARSKWQRSLMCYKSILVMRSIPEILERTHDNTSLAISRHLIEESTSSSTSGSSS DNENSHFPKRHFGSTPELHLSIFDASSHQEPPKPSSEEKHSKMSVPPVKPMRRKYASTKA EVGDKSPTETKELMASILKEKEEGLHPRPRDERAEQSQRSGAAESSSARTSTESTSHLCQ KEKPDIFLSDKDRIEKAGDGTEKPPVCVPRQSVIKSTFYSQAAELPARGPSSPGREFRRH LDRARRTFRKAGYSKVPLSGLREPLLEQFELEEEEGKSDDGDDHRESLLTKSASFDTARK PPHPAIAGASRSRSLDDYRLRASRSVREQDILEEDCDILSQESCPEGSDHCDISAGPSKG CSVDTSKQEDFRRASKDCSEEQPPPSTKCEGNGCPAVTVQQLERLPVSPHRSENRKHLLK KSKAAYFEEEVEDLEGKSTSLTAQCLDVTASSAQKHESMEGKSPPGSASDTAFQEGKQSI STLAQSDTTSKSAPTSKEGAYLPQESAHSTDIQPDLKGGSLLIKRTAPVPPWKDERHKHS HEKTSAHSVAKSDLMEHESTAVLTGPQTETDSLPVCKDKSQELPDQSVPVTTALVGKRPG TLTALQTADEGVHQKLKTYEEVRSGVLEDEGPGVTATTPPSAHDGESQTHKRAPVHGDTA SANLKEEHLVVPKVPPPKSMPTLVSDGARQAERERPAHSKERLAALRRESSAVTELVPSL VHETEIEGAEPQKVSKGSGMVPAVLESRHPARTASSQNTGLPSVHDSEQREHPKASLRSE VRSAVTASGSQAAGQTMPAPFPKAGRQVSEQHRAACPSGRVSADLEGGPPGVLTASQPEV APAPVYELEFEEHPKLYDEGRGVALESGSCDARRTVPPSLHRDQSQELSHHRSSFYSDEE SAVLEGLVDEMVSLSEEMNVWAESVSGEEEWRKHISPPTEMFHKGPGSQAPMDTAFPSVQ GGKREVSELDDLAEPYPAMSETSVVLEGQGGQMVPHECEHLEDLAFESPTSSQVSVSSTD SLDAGKRPSQVSVSKDTGKHPEVSLVKIKDLSDETPSLGSGTPKLDISEVEPAYLNFSDL YDIVYFPFEFLNYRKPPPKPTGRRFIPFGERARSPPAGHLHKDKRLCIREEAEDRNRKNH LEISEDSKATNLLAMGKGSESHKEIYGHQKDSSGKQRSSFYNKPGLFKPYARSHSVEQSV EQSLKKKVKASVAHISRILKGKTSPEPEEEFGELGSEAVEKELLTGAEGSLKRKSGLSSF KLSSLMPKEKAPLFVEELIDQAAAVGQCVTLSCRTAAHSSLHINWFRDGIPVHSSSQILI SATLKNFQLLTILSVSADDFGIYTCVATNSLGSASTSCIVRKAELPPSPPSPDIVEVYED GAQVAWKPVETNIPIHYTVQCKSEDGEWMTLASDIADCCYYAKNLSRGFIYSFRIACTSK AGMGPYSNPSAKVKITGKDEMELRAAMQNFPPAAAEEESEIITPSEPFPTYQTYAFQTEI KRGRFSIVRQCREKVSGKTLAAKIIPYWQEDKQTVLLEYQILRKLHHTNIAQLKGAYVSP RHLVLIQEMCVGPELLHSLALRTSYSEVEVRDYLWQTLSAIEYLHAHNILHLDLRSENMI ITEPNLLKLLDFGNAQFYPQDKVITMDKCMDYVETMAPELLTEQGALPQTDIWSVGITAF IMLSANYPVSSDVACEFLRMTRKGKVKLTRCYAGLSGGAVSFLQSTLCANPWGRPSASEC LQSPWLQETGLDNRQQALVTFPTTKLRNFLTEREKKRGLLCSKYGLMIAQ NT seq 31113 nt NT seq  +upstreamnt  +downstreamnt atggattacagctcattcagcggagtcccccggttcttgacccgtcctaaggcatttatg gtgtctgtggggaaggatgccaccttgagctgccagatcattggaaaccccatcccagct gtgagctgggaaaaggataaacttccagtccagtctgggggaaggtttaaaaccacagaa gatggggatctctatcggctaacaatctatgatctgagtctggaggacagcggccaatac atctgccgggccaagaacaccatcggggaagcttttgcagcagtcagcatcaaagttgga gaggagaccacagtaacggagtcggccccatacttcatccagaaaccctcctccatcaaa gtaacactgggagaagatgccatgttcaaatgcaaagtccaaggtagcccccccctctcg gtgaactgggagaaggatgggagacacctgcggaaccgggctgatgccggccgcttccag atcgagtctgctggggagtcgaacgctctcaccatccagtgtgcccggctgggggacagc ggcacctacacctgccgggcagagaatcccatcggctctgccagcgcttcagccgcactg gtggtggaaacgcagggctcttccaacccgggcagcagcagccacttcgataccagctgt ggcaagacggcatccttgttgtctcacttgcaaaagaggcgggaggagatcaggaagatg gacgtctcctatggcgctcttgattcatcatctacccagtcttactccacagcagaaggg ttgtctggcatcggctatggccgctcccgggattacgagagggtggctggatttaccacc aaaggggcccgcaacgcaacttttggggcgctgacacgcatgtgcagcgtgacggaaggg aagcacgccaagctgagctgctacgtgacgggtgagcccaagccagagatcgtgtggaag aaggacaacgaggtcattttggaaggacggcgacatgtcatctatgaggatgatcaggag aactttgtgctgaagatcctcttctgcaagcagatagacaacgggctgtacacttgcaca gcctccaacctggcaggcgagacgtacagctccgtgctcgtcaccgtcaaagaaccctca atacccttcaaggaaaaactgagggatcttgaagtgagggagaaggaatctgccaccttc cagtgtgaagtgcctgttcctagtacagagacagcttggttcaaggaggaaaccaaactc cggcagagcaagaaatacaacatcgaagaagagggcacgtatcgccgcctcactgtccag aatgtcaccgcagatgatgatgctgtctatatctgtgagatgaaagaagggagcaggacc attgcagagttgtctgtccaagggaacatcattaaaaaacttccacgaaagacagcggtc ttcataaatgatacagccatcttctgtgtggagctggacaacgaatgccagaacatccga tggctgaaaaataaagaggaagtgaaacccagtgatcgaatctccatcacatgctctggc aagcaacataccatgatcatccgagagtgtaagatggaagatgctggtgagattgccttc ctggctgatgaaagcaggacttctacccagttcactgtgacaactcccagaaaacctccc acccaacccccagctgaccccgtggtgaaaaataaaacagaaacctcagtgacactagca tggtcccctccaaagatggaccgccccattccaattgatggctacattgtggaacgcaag aaactaactggctttacctgggtgaggtgccatgagtctcatgtccctgtcccagagttc acggtgagcaacctgtcagaagagtctgactatcagttcagagtgtctgcagtcaacgcc tatggacagagcccctacctggagttcccagggagcatgcacctcgagccagtcctggct gtgaaaacccccctgacaaccgttgaagctgtacctggaggggatgccctgtttactatt gaccttacaacgacatgttctggcacttggtaccttaatggtaaagtcttacaggaaagt gagacctatatcattaagagaactcaaactactcataccctgatcataaagaaggtcacc aagaatgatgatggagcagaaataaaatttgttgccaataatgttgacaccagcaccaag atgagagtgaaaggtgctgcagtgagatttaccaacaagagcagagatatagaaaaggtc tctgttcggctgcgggaggaagccaaacttcaggctgagctttcagatgcagaggctact gtgaagtggatgaaggatggaaaagagctcaaggccagtgaaaaatatgaacttcaaact gtggggaagaagcacatcctgaaaattcacaatactgcagcagaggatgctggagtttat gagtgcatttgtgaaggggataaaatggtctatcaactttcagtgaaagcacttccaaac ttcataaacaaagagaaaagtggaggtgttatcagggccatcgctggaaaacaggctgaa tttgtttctgagacctccgaggccaacgtcatggttaagtggtacaaaagtggcaaagaa atcacagccagcaagaaattcaccatggaagataaaggaaaactgcataagcttgtggct tcagctgtgacaaaagaagatgaaggaatatacacgtgcaaaattggagacgatactctt atttttgatttaaaagtctcagatgaacctgttaattttgtcaacaagcccaaaacaact ccagaaatatcagtcagtccttctgaagaccttgagctggtgtgtgaggtgtcagctgtg agtggagctgttgtatggaagaaggatcaaactgaggtgaagcaggaccagaggacaaca atcatctcccaggggacacatcgcaagctcatcatcaagaaggtgacacagcaagaccaa gggagctatacctgtgaaacaaaggatgacagaacaacattccaagtcaaagtcagagag acagaagacatgtttacaaacaaggacaaggtccagaaggaggtgaaagctgccctatca gaagatgccaccctgagctgcgaggtggcccaggagaagaccgatgtgaaatggtacaag gaggggaaactgatcacctcgagcaagaagttcaaggtggagtcgcagggcaaatctcgt cgtctggtggtgggtcaggtggagaagaaagatgctggggagtacacctgcgaggctgct ggccagaaactgaccttcaagcttgatgtcacagagccagaagttgtgtttacaaacaag gacaaggtccagaaggaggtgaaagctgccctatcagaagatgccaccctgagctgcgag gtggcccaggagaagaccgatgtgaaatggtacaaggaggggaaactgatcacctcgagc aagaagttcaaggtggagtcgcagggcaaatctcgtcgtctggtggtgggtcaggtggag aagaaagatgctggggagtacacctgcgaggctgctggccagaaactgaccttcaagctt gtcgtcacagaggcagaggatgcatttatcaacaaggacaaagtgaagaaagaggtgaaa gctgcaccatcagaagatgccaccctgagctgcgaggtggcccaggagaagaccgatgtg aaatggtacaaggaggggaaactgatcacctcgagcaagaagttcaaggtggagtcgcag ggcaaatctcgtcgtctggtggtgggtcaggtggagaagaaagatgctggggagtacacc tgcgaggctgctggccagaaactgaccttcaagcttgatgtcacagagccagaagttgtg tttgcaaacaaggacaaggtccagaaggaggtgaaagctgccctatcagaagatgccacc ctgagctgcgaggtggcccaggagaagaccgatgtgaaatggtacaaggaggggaaactg atcacctcgagcaagaagttcaaggtggagtcgcagggcaaatctcgtcgtctggtggtg ggtcaggtggagaagaaagatgctggggagtacacctgcgaggctgctggccagaaactg accttcaagattgatgtcacagatgatgtgtttgaacacaaagacaaagtgcaaaaggag gtgaaggcagtgttgaaggagaacaccaccctgagctgcgaggtggcccaggagaagact gatgtgaaatggtacaaggaggggaaactgatcacctcgagcaagaagttcaaggtggag tcgcagggcaaatctcgtcgtctggtggtgggtcaggtggagaagaaagatgctggggag tacacctgcgaggctgctggccagaaactgaccttcaagcttgatgtcactgaggcagaa gatgctttcatcaacaaggagaaggtgcagaaagaggtgaaagctgcaccatcagaagat gccaccctgagctgcgaggtggcccaggagaagaccgatgtgaaatggtacaaggagggg aaactgatcacctcgagcaagaagttcaaggtggagtcgcagggcaaatctcgtcgtctg gtggtgggtcaggtggagaagaaagatgctggggagtacacctgcgaggctgctggccag aaactggccttcaagcttgatgtcacagagccagaagttgtgtttacaaacaaggacaag gtccagaaggaggtgaaagctgccctatcagaagatgccaccctgagctgcgaggtggcc caggagaagaccgatgtgaaatggtacaaggaggggaaactgatcacctcgagcaagaag ttcaaggtggagtcgcagggcaaatctcgtcgtctggtggtgggtcaggtggagaagaaa gatgctggggagtacacctgcgaggctgctggccagaaactggccttcaagcttgatgtc acagagccagaagttgtgtttacaaacaaggacaaggtccagaaggaggtgaaagctgcc ctatcagaagatgccaccctgagctgcgaggtggcccaggagaagactgatgtgaaatgg tacaaggaggggaaactgatcacctcgagcaagaagttcaaggtggagtcgcagggcaaa tctcgtcgtctggtggtgggtcaggtggagaagaaagatgctggggagtacacctgcgag gctgctggccagaaactgaccttcaagcttgatgtctcagagccagaagttgtgtttaca aataaggacaaggtccaaaaggaggtgaaagctgccctatcagaagatgccaccctgagc tgcgaggtggcccaggagaagaccaatgtgaaatggtacaaggaggggaaactgatcacc tcgagcaagaagttcaaggtggagtcgcagggcaaatctcgtcgtctggtggtgggtcag gtggagaagaaagatgctggggagtacacctgcgaggctgctggccagaaactgaccttc aagcttgatgtcacagagccaaaacctgcattcataaatgaggaaaaggtccagaaggag gtgaacgctgtcctgacagaaagtgccaccctcagctgtgaggtagcacaggatgcaacc gaagtgaaatggtacaaggatggaagactgctcatttcctctaggaaattcaaagtagaa actgtgggtaaaacccggcgcctggttatagagcagctggagaagaaagatgctggagag tacatctgtgaggctgcaggccagaagctgactttcaagttgaaaccaactgaaccagaa gctaaatttgaaaataaagttgtccagaaagagcctctcattgttcaagaatatgaaagc atcacactgtctacttcagtaactcctgaaactgctgcagtaaagtggttcaaggatgga acagaaatcaaggcgagcaagaaatacgaaatcaagagtgagggggcatctaggaccctg acagtgaacctggctgagagcacagacacggccgtgtacacttgccagacaaaaagcgac aagcaggaattcaaagtgcaggtgaaagaaatcccagtgaagtttgccaaaaaacttgaa gctgttaatgctgagatcggaggcagcgtctctctgacctgtgacgtgagccatgccaaa gggaaggtggtgtggtgcaggaacggagttcagatcaagcccagcaagcgtttccagata catgaggaaggggtcaagcgaacattgaccataacagggatccgggctgaggacgaggga gagtactcctgcgagtccagagacgacaagagcagcgttaccatcacccccaaacctccc agagtggtgaaatttgttacgagtctcaacagcgtggtctctgaggaaggaaaagaggct gtgttcaagtgcaccgtctctcccagtgatgctgtggtcacttggttcaggaatggtgtc aagattgaagccagcgagaagtatgtgatctcacagaaggacaccaaccacagcctcacc atcactgatctgacactgaaagatgcagctgaaatctccgccaatgctgagggcgtagaa agcacagccaatctcagagtccgagaggcctcaatctcattcaagaagaaactggagccc agaacagttgaagagagggacacagtgaccttggaggtagagctgactaagcctgcagag gtgaagtggatgaggaacagcatcgtattgaagcccagtgaaaaaatagagatcaaagct gagggaacaaagcataccttggtggttaaggacatctcctttgcagacaggggcttctac tgctgtgagagtcctgatgacaagacccaagccaagatcaacgtggaaatgagacagatc aagctggtgaaaggtctgcaggccctcgaagtctctgagaaaggcaccgtcacctttgag gtggaagtgtcacatgaggacgtggaagggacctggcagaaggatggcattcggctgaag ccttcaccaaacatcagtattggtgtcctggggaagaaacgttccctgactctttcttca gtgtctcttgaagatgcaggactcatctccttcaaagcagatggcattcatacatcaggg aggctcactgtcacagaattgcctgtgagaatcagcaaacctttgacagatgtcagtgta actcagaaggacaaggtcacattcgagtgtgagctgtccaggagcaacgtggatgttaag tggttcaaggatgggaaggagctccagcaaagtaaaaaagtggggattatttcccaggga aataagagaagcctcattattcataagtgtgaatatgaagaccagggaacctatacttgt gaagcagctgaagacaagacatcagctaccctaaaagttcatgcccgagatatcaagatt gttaaaccactggaagatgtggaagtaaatgaatatgagagtgcgtctttcgtctgtgag atttcacatgatgaggtccaaacccaatggtacaaaaatgacaacaagctgaaggctgcc gacaatattagaatgcgtcaagatggaaagacctattcgctgacttacatgcgcgttcaa gtcgaagatgcagcagagatcaaatttgtagcagaaaaggcagaatctcgtgcccagctt actgtaaaagagttacctgtaaaaattgtgaaacctttgcgagataagatcgctcttgaa aaacatcggggattcctggagtgccaggtgtctcgtgccaatgccaaggttaggtggtac aagaaggaccgtgaaattcaccctagtgacaaatatgaaattgtgagcgatggtgtctat cggaaactcatcatcaacgatgcagattatgaagatgaagacacgtacacttgtgacgcc tttgatgacaaaagcagtgctaatttctttgttgaagagcaatccattagtattgtaaag gagttgtgtgatgaggatgtgactgagcctgaagaagccaagtttgaatgtgagatatcc attccatctgtgaaaccccccaaatggtctctacacggagaaatcttacaggctggcaga aacattatcatgcagcaagaaggcaccatccacaggctgacaatactgaaaaccagtgcc gatatgacaggcaccattcagttctccattggcaaatcaaaatccacagcaaacctgctt gtcagagattaccacatacagatcaccaggaagatggaggacaagacagctctggagcga cactcagtcatcctgtcctgcgacttcaggccttctccaaaggttgtgaagtggttcaag gaccacgcacccatcgagccctccgagaagtacaaaatcaggcgggagcagcattcagca gaactcaagattttgaaggtgaagcccgaagatgctggcgtgtacaagtgcagggctgga aatgcagagaccgaagccacgttgactgttgaagcccgcaatgtagaaatactcaagcac ctgcaggacgtggaaattgaagaagagagttccgctgtcttctcctgtgagctgtctcac gatgacgaggatgtggaatggttcctcaacggcaccctcctttacaccaacaatttcaat gacatcaggaacgttggcaattgctacacactgacgatgaagcaggtcaagcctgaggat gccggcacagtgactatgaagtcagacaaggtgtcagagagcgtgcgtctgaaggtgata gagaagcctgctgtcttcatgaagtccttggacgatgtctttggtgaggagcgaggtgtg attaaactggaatgtgaagtctcaaaagagaaggtgaaacctgtttggaaaaaggatggt gtgacactcacttctggtaacaagtatgagcagatacagtctgggaagaccctgtgcctc cttatccatgacctcgaaaagacagatgcaggtttatacacgtgtgatattgacactgat gttgccaagtcaaaggtcagcattcaggaactgaacattggcatcaccaaacggctgaag aacactgaaatccaggagggagaagattgtacttttgagtgtattttgtcccatgaaagc attgatgacttcaactggacgctgaacgggagcaaagtggaaagtggtgggcgatttaaa gcctctaacatgggtcggaaatacatgctcaatatcaaaagcgtgattcctgatgatgct ggggaagtcattttcacggcccgtggtctaacctccaaggcttctctggttgtgaaagaa aaacctactgaggttacaaaacagctggaggataaaacatcagcagtggggcaggacatc agcctgagctgtgaattgtcaaaacctgatgtaagcatcagatggtataaggatggcaaa gcaatccgaaaaagccagaagtatgacttgcgccaagagggaacacgggccattctgatc atccatgcctccaccatcaaggacagcggggagtacacctgtgagacagagttctctaaa acaaaagccaggatcacagtgcaagaaaaacctaattattttgtcaaggaactttcagat ctaaaagctgatgaaaacggaactgcagtttttatgtgccagagcgagaaagctgcaccc tctgtggtctggaggaaaggcatagctgaactcagggctagcaggaaatacgagatcaca cagaaaggacaagtcctgcagctgaccataaataacttggagaaaagtgacagtgacact tacacctgcgacattggtgatgcccagtccagagccaagctagtcgtgcaaggccagaaa gtgctaataacagaagacctggaagatgtcactgtgttagaaggagaatctgccatgttc aaatgcagaatctctcctgtagactatagcaaagtgcagtggtttttggataaaacccca ctccataccaatgaacttaatgagatccagtctcagcctggtggatatcacttgctaacg ttgaaaaaactctcactgaaggactcgggggtcattacatttgaagctggtgataagaaa acatctgccagtttggttgttaaagagaagccctgcatcttcacaaaggagctggctgat actgaagtcactgagggagaggatgtgatccttcactgtgaaacctccaaatcagacagc cctgtaaagtggtgcaaagacgggaagagccttaggaattcttccaagtataacatcagc cggtcgggatttgaagccaagcttgtcattcacagggcagaagaaagagacagtggcaga tatgagtgtgaggctggagcagctaaaagtagtgcggttattactgtcaaggaaatacca gttcttttcaagcaagagctccaaaacgaagaggctaaagaaggaaaacaagtcaagctg acctgtgagctcagcaaacctgatatgccagtgaaatggatgaaaggagacgctgttctc tatgctagtgagaagtatgaatttaagcagtgtggtactgtggcagagctcattattcga gatgtcacgtcgatagatgctggggactatacctgcagcactggggaacagaagaccact gctcgggtgaaagtaaacgctgtgcctgtcctttttaaacaagccctggagaacacggaa atggaagaggggaaatctgtctccttgcgctgcgaactcacaaaagctgatgccaccgtg gtgtggaagaagggagaagccacgctgcaggcaagtgccaaatatgaaatgaagcagaag gggacagtggcagagctggtgattcataatgcagagccagaagatgcgggaagatacatc tgtgacactggagaccagcagaccacagcccaagtcaaaatccatgccgtctctgtgctc atcaaagaagagctgaagagcgtggaagctgtggaaggtgggactgccaccctgcgatgc cagctgagcagagaggcccccgtggagtggaggaaggggcacgctcttctccggccaagt aacaagtacaggatgaggcaggagggcatggtggctgagctgctgattcacgatctggac ccaaaggatgctggagactatacatgtgtagtgggggaccagaaaaccacagcagcctta tcagtgaatgccctgccagtccgtttcaaaaaagagctgaagaacgaagaaggcaccgag agtgggacggccacgctgcagtgcgagctgagccaggcggtgggctcggtcgagtggagg aaggacgggaaggtcctgatgccaaatggcaaatacaaaatgagacgggaagggcgtttt gctgagctggtgatccaagacctagacttggcggatgctgggaactatacctgcgtgtgt ggagatcagaagacaacagccgctttgagagtgaatgccttgcctatcctcttccaagaa gaaatgttgaacaaggaagctacagagggggaggcagtcactttgcactgtaaactgagc aaatcagccccggtcgagtggagaaaggggaatatggtcctgaagccaagtgaaaaatac aaaatagggcaggaaggtccctttgcggagctgatgatccgtgatttggatttggcagac gctggtgattacagctgtgtgtgtggagatcaacagactacggctgctttgacagtaaat gtcctgcctgctcttttcaccaaagaactgacagatgaagaagccacagaaggtaaaagt gtctctctgcattgtgagctgaacaaggctgctgctagcgtggagtggaagaagggattc aagaccctcaaatcaagtgacaagtataaaatgaagcgagaaggtgtcgtggctgagctt acaatccaaaacctagacacgacggatgctggaaattattcctgtgtgtgcggagaccag cagactatggcagttttaacagtacatgctttgcctgcatttttcaaagaaggattgaag aacagagaagccacagatggtgcaacagccactctgcactgcgagctgagcaaggtcggt gtcccagtggagtggaaaaaaggggacaagacgctcaaaccgagtgataagtataggatg agacaagaaggtactgctgcagaactgttgatccgagatctggaggtagaagatacagga gaatatacctgtgcatgcggagatcagaagacctcagctgtcttgacagtccatgctttg cctgcactgttcaaaaaggaacttgtcaatatggaagccgcagaaaacgggacggctgtt ctgcagtgtgagctaactaaacccactccggtggagtggaggaaagggcaaaaggtgctc aagcctagtgagaagtacaaaatgagactgaaggatgccgttgctgagctgacaatccat agcctggaggaacaagatgcaggagattacacgtgtgtgtgcggagacaagatgactaca gcatccctgacagtgcatgctcttcctccgcattttaaaaaagagttgaagaacgtggaa gccacagaaaacggcacagccactttctgctgtgagctgaacaagcctgcagcagccgtg gaatggaggagaggaggcagagccctggagacaaatgacaagttcaccgtgagatgcgag ggcacaattgctgagctggtgatccgtgatttagatctcacagatgctggagattacaca tgctgttatggagatcaggaaaccaccgctgcgctaaaagtgaatgccttgcctgcacac ttcaagaaagagatgaagaatgaagaagccacagaaggtggaacagccaccctacaatgt gagctatctaggactgcctctgtggagtggaaaaagaaacacaaagtgctcaaatcgagt gaaaaatatactatgaggcaggaaggtactacagcacaactgctgatccatgctttagaa gtcaaggatgctggggagtatacctgtgtgtgtggagaggagaagactactgcagcactg gcagtgcacgcccttcctgctctcttcaaagaagagttaagaaatgaggaagccatggag ggcgaagtagtcactctgcgctgtgagctgaccaagaccgcttcagtggagtggaaaaag ggacacacagtactcaaacctagtgagaaatacaaaatgaggcagaaggatgttactgca gaactggtgatccataatctagatgagactgatgctggtgattatacctgtgtgtgtggg gataagcagtccacagcttccttggcagtacacgcactgcctgcacgcatcaaggaaagc ctgaaggatgaggaggtaacagaaggtcaagcagccactctgcgctgtgagttgaccaag gttgctcaagtacagtggagaaagggaagcagtttgctcaaagtcagcgacaaatacaaa atgagacaggagggcacggtgatgaagctgcttatccatgacgtagaattgaaagatgct ggagagtacacttgcatgtgtggagaacaggagacaacagctgccttgaaagtgcatgcc ctgcctgcacttttcaaagaagaactgaaggacctgcaagccatggaaagccaaacagcc actctgcgctgtgagctgaccaaggctgcagctgtgtcatggaagaaaggaaacaaaata ctcagggcaagtgaaaaatacatcatgcggcaagataatgcccttgctgagctggaaatc tgtgatctagagctgcaggatgcgggagattacacctgtgtgtgtggagaccaacacacc acggcttctctgacagtgaatgccctgccggtgcttttcaaggaagaactgaagaatgaa gaagtccaagaaggagcgtcagtctctctgcgttgtgaattaaccaaagcagctccagtg cagtggaaaatagggtccaaagtactcaaagcaagtgacaaatatcaaatgagacagcct ggcacaactgcagagctgttcattcatgacctagaagtaaaagatgctggagattacacc tgtgtgtgtggtgatcagaagacaacagcaaccttaacagttcatgctctgccaccgctc tttaaggaagagctgaggaacaaggaagcagaagaaggtggagaagtcgccctgcactgt gagctcagcaaggctgcgccggtggagtggtggaaggaccagaggatcctcagagcgagt gagaaatacaaaatgaggcaggaagggaccaaggcagagctggtgattcatgaaatagct gaggaggatgcaggagactacacctgtgtgtgtggagagcaccagactacagctgtctta acagtacaggctgtgccttcatttttccgagaagaaatgaccagcaaggaagcggtagaa ggtggaacagtcacattgtgctgcgaacttagcaaggcatctgcccatgttcagtggaag aagggccatcgagtcctcacaccggacaagaagtacagcatgagacaggaagactgtgtt gtggagctggtagttcacgagttagacttgaatgatactggagattatacctgtgtgtgt ggagacaagagcaccacagctgccttaacagtgcatgcactgcctccagaattcaaaaaa gacctgaaggacctagaagctgtagaaagtgggacagctgctctgcactgtgagctgact aaacctgctgcggtggagtggaagaaagggcaggaggtgctcaaagcaagcagcaaatat aaaatcagtcaagatggtgcggttgcaaagctgattatccatgagctggatgtggaggac actggagattacacctgtgtgtgtggagatcagcagacaactgctactttgacagtcaat gccctaccagcactttttaaacaagacctgcagaataccgaggcaaaagaaggtggtaca gcaacactgaggtgcgagcttaccaaacccaatgctccggtagagtggaggaaaggagat actactctctaccctggtttgaaatacgaggtgaagcagcagggctgcactgctgaattg gtcatttatgacttagaactggatgactcaggaaagtacacctgcgactctggagatcag cagacaacggctgtggtaactgtacatgcactgcctgtcacatttaagcaacccctacaa aataaggaatcagaggaaggaagtacagctacattttgctgtgagctgtcgaaacccaat gctgcagtggaatggaggaaaggaggagtggggctgcagcccagccagaaatatgaaatg aggcagagggaatgcctggtagagctattaatacataatctcaaattagacgatacagga gaatacagctgtgatactggggatcaggaaaccaaggcatctttaaatgtgaaagctctg ccagttcttttcaaaaaggagctcaaagatgaggaggcagaagaaggagctgcggtgaaa ttccagtgtgagctgacaaaggataatgcaacagtggagtggaggaaaggcaccatggag ctcttcccatgcgccaaatatgaaattaaattaagcggtcgcacagctgaacttgtgatt cataacgtagaaccagaagatgcctctgattacacatgtgatacgggagaccagcagagc acagcagtcctcacagtgaatgccatcaaaccccggctgaagcagcagctgaagaatgaa gaagtggaagtgggaggaatggccaggctgcgctgtgagatttccattagcaaagcggaa gtggagtggaggaaagatggagttgtccttcactcgagctccaagtacgaaatgtggcag gatggcaccctccgcgagctgcgtgttcaccacctggagcctagtgatgctggagagtat tcctgcaaggctggagatgagacaagctctgcaaaactgaccgtgaaagagcctgacgtg accatcgtgagtggcctaaaggacatggtggtgtttgaaggggatgatgtcacgttccag tgccaggtttctcatgagaacgcaagggatgttgaatggaagctgcaggatgtcgctctg caaaataatgaaatgaatgagatctcagttgaaaaaggaaagattcacaccctgatgtta aggaaggtgactgagcaggacattggcaccatcactttccgagtgggaccccacacgtcg acggcagagctcacagttaaagtgccacctccagtctttaaggagaaattacagagcaca gaactgcaggaagaagaaacagccatcctccgctgcgaggtctcccaggctaatgccacg gtgaagtggaagaagggcacccaggtgatttccccgagctccaagtatgaaatcaggcag gagggaacaatccataccttaaagatttatcacttaaaaccagaagacgctggcaaatac acctgtgataatggaaatgaacaaacgacagccactttaactgttaaagctttgccagtc atcttcacacaaccactccagaaccagcaagccgaagaaggtggcaccatcactttgagc tgtgaaatctcaaaatcaaatgttgctgtgcagtggaagaaggccggaacagtactgcga ccaagtgagaaatacaagatgcatcaagctggatccatggctgagctgacgattcacaac ctgagtgaagctgatgctggggaatacgtgtgcgacacaggggaccagcaaaccacggca gctgtgttcgtgaaagaatcagcagcaaccatagtggagacgctgaaggacgtcacttcg tatgaaggagaggacgcagtgtttgaatgcaggctgtcccgggaaacaactcaggatgcc cagtggttcctgggggatgttcccctgcaatccaatgaaatgaatgagatcagagtccaa gggacacgtcacactttgatcctgaggaaggtgacactagaagactgtggacccatcagt ttcaaagtcgggcagcatacctcagcggcacagctaacggtccaagttgctccggtcacc tttgtaaagacgctccacagcttggagctacaggagggtggcacggctcacttgtcctgt gaggtgtccaagcctgatgtccctgtggagtggaagaaaggtacgtccgtgatccactcc acccagaagtgcagcatcaagcaggaggggaatgtgcacaccttggtcattcacgatttg aaccgtgcggactcaggggagtatagctgccacacagctgatgggaagaccactgccaga ctagaggttaaagccctgcccgtgcttttcaaacactggctgaaaaatgaggaggtggag gaaggatgcacagccatgctgcactgcgagctgacgaaaccaaatgcatccgtggagtgg cggaaaggagatacggtgctgcagccaagtgacaagtatgagatccggcaagaggggaca cgtgttgagctcttcatttatgatgctgaggctcaggatgctggcgattatacgtgcgac tcgggggatcagcagaccactgcatcattgcaagtcaaagtactacccgtgctgtttaac aaagagctgaaaaacgtagagtctgaagaagggggaacagctgtcttgcactgtgagatc tccaagccggatgcccccgttgagtggagaaaaggaggggtggtcattcagcccagtgac aagtacgagatgaagctgaaaggcagcattgctgagctgatcatccatggtgtagaggct gatgactgtggggattatacctgtagcactggatacgagatcaccacaggttctgtgtat gtgcaagaagaagaagcagtcatagtttctggtttaacgaacacagacgtctttgtgggt gagtcagccacgttcacctgcgagctctcgcatccgggcgtgaagaacgtgcagtggtgg ctcgatggatccccccttcacaacaactttgtgactgaaatctctgagcaggacgggatg atccacactttaaccctaaatgacgtggcgtgccatgactcaggcactgtcaccttcaga gctgggtcccttatatcttcagctaaattattagtcaaagatccaaccattgaagtggtc agtcccatgcaggatataactgttgatgaagatggcacagcagagttcatatgccaatat tctaggccagtacacgccatatggaagaaaaatgatcaggaaatacatgcagatgggcag cgagtgattatcgatcaggactggaatgtaagcatgctaaaaattaaacctacggtacca gaagacactggcatctattcttgtgaagctgaaggcattaaagtgatggctgcacttgat gttcaagccaagaacagcattgtccagggcttggagaacgtggaagccgtggaaggaggg gaagccctgtttgaatgctatctttccaagcccgaatgctacaattacaactggctgatt gacgatgaacctgccaaaactacagaaaacactgagatggtttactttgaaaatggacgc aggcatcttctgctgctgaagaacctaactccacaggacagctgcagggtgacttttatg tgcagcgatgcggtgacctcagccttcctgacggtgaaaggatggcgcctacaaatcttg cagcctctgacagatgtggaagtctctctgggggagaaagctacatttagctgcgttcta agtgaagctgtgccacttactgaagttgcgtggtataataatgacgtagagatccagtcg gatgaggactgggaggtacaagcagatggaaataaatacaaacttattctgaaaaaagcc caaccgcatcattctggagaggtgacctttgcttccagggaagcaattgcatcagccaag ttatcagtgatagcccaccctgaaccacctgaagaaccagaagttttaagtaagaacagc cactctgtaactctgtcttggtacaagccattgagcgacggcggttgtgacatcctaggc tacaacgtggagaagaaaatcccaggtattggctggcagtcatgcaacaagggcattatt caaaacacggagtttatggtggacgatctcaccccgggtgaaccctacagattccgcgtc tcagctataaacaaagttgggtccagtgagccggtgcacttccctcagatggtgcggcta gaggctccagttacagtcacccatcctttggtgggaggatcagtttcagaaggggaggtg gctcgcttggagtgcaaattatcaggtgaaactgaagagaaagtcacatggttcaaagga aaagaagaaatacaagctggagggagatatgagatcatctctgatggaaaaaagcagata ctcattattcatgcatttaaacctgaagatcaggacacatatacctgcatggtttctcca gaagtcaaatctgttgccagcttgtgtcttgaagttcccacagtgacaatgctaaaagag attgccagtgaagctccctctgcaacgcaaccagaagagctggtggatggccatgtccag cccagtttgccccctgaggctgctcaggagggagaccttcacctcctgtgggaagctctg gccaagaaacgccggatgagccgggagcccaccttggattccatcagcgaggtacctgaa gaggacgagaagcttcagaagttgaggaaggaggaagcagagatgtctcactattactca gaagagtactccacgtgcgatgagttggctaggacaggagaagcagatttctctttcaca agctcagatgatgagtctagagctgggactccttcactagtgaactacctcaagaaagct ggaaaggcaagtgtcagtgttactagcaaggctcagtctatctccacggggaaattatgg aaacagtgggagaaatccagtgtggagactgttgtggctgccccagctgctaagccagct aaaccagaaatatcagatttagatgatccttccatgaacaaggccgctgtgaagatccag gctgctttcaaaggctacaaagtcaggaaagagatcaaacaacaagagtgcccagtgttt actgagaccttcaaagatttctctggtgagcctggaagcactctccaccttgagtgtgtg gctcacagcaaaactgacatgaaagtccgttggctgaaagacggagaagagctttcagat ggtcgctactatcacatagacaattacagtgatgggacctgctctttgattatcactggc ctggatatgaaagatgcgggtaaatacacctgtgaggcatccaataaatttggcaaggtt tcacacagtgctaaggtggttgttggcactcaggaacctcaagctgttcataaggagaag caggttaaacaaagcactgacagtgagacagagagctcatctggcagtgagttggatgat gctttccgtaaagcaggaaggagacttcatagactcttcagggccaagatctcaacagag atatctgatgtggaggaagagctctttgtcagtgcagatgaaggggacatagaggtggtc gaccatcagacgtatcgtgaggatgaccagtatatctacatcaagtttgaaatcttgtct gaggcaaaaactgctgccactcgattcagagagatgtttggtgctctgggaattcctgtg gagattgacattttggaacaaggccctaaaaaaatggaattgcgtattgggaaagcaaca ccacccacccacgggaagtttgtgccaccagtagtgagacctccaccacctttgctgact tctgatacagctcccatgttcatgactgagctccaaaaccaagaggtacaagatggatat ccagtcagctttgactgcattgttgttggcaaaccgctccccacggttcgctggttcaag gatggcaaagccattgaagaaaacgatcattacatgatcaacgaggaccaggaagggtgt catcagctgatcatcacagctgtggtccccaccgacatgggtgtttaccgttgccttgct gaaaacaacatgggagttgcttcaaccaaggctgagcttcgagtggacctgaccagcact gactatgagacagcagcagatgcaacagagacatcttcttactacagtgccaaagaatat atttcaagccgagaacaggaggaatctaccactgaggaggagcaattgccccagatcctt gatgagcttcatgatattcatgtggcacctggagcatcactggctaaatttcacctgaag gtgaaagggtacccgcagcctcgtctctactggttcaaaaacggacagccgctaaaggcc tcggatcgcatcctgaaaactgataaacaggaattccactcactggaaattcgcgacgtc actaaggcagatgctggccagtactcaatatttgtcatcaactctgctggttctgcatat tcgtcggccaggctggtagtcaaagatcctgatgagaaagaagagccatcagaaacagat tcccatgagcagctgataccaccaaggttcctcgaaagatttactaataaaaaggtgaaa aaagatgcaagcatcacattatctgtaaaagttgaaggacatccaccaccaaccattact tggctgaaagaagagtctcaggaagacatcctgtggatcaaaccagacactcctgggtat aaacttgccagttcaaatatgcatcacagcctaatcctgttggatgttaaaaagaagtac agtggagcttacacatgcattgctaccaacaaggctggccagtccatctgcaccgccacc ttagaagttgcagatgtgaaagaggctgaagttctgacccaggagcgtgtgatggtgtca gaagccatcatgaccacactgggggctattcaaccctctgaaacaagagaaggagacctt gaagctggtagagaaggtgtacccaaaagccctatttcattagctgatgttggctcggaa gagttcttccagaaactcacctcacgtatttcagaaatggtatctgcaaaaataagtcag gctacacttcgagtgccaggtgcagaaagtgatgatgaatcaaaaactccctctgcatct cctcgccatggacgatccagaccttcatccattgctcaggagtcttcctctgagtctgaa gatggggattccagaggagagatctttgacgtctacatggtcacagctgactacgtgcct gctgctcctgacagggagaccatcactttgaaggaaggccaatatgtggaagtccttgat tcagctcatcctctgaagtggctggtcaggactaaacccacaaaatccagcccctctcga cagggttgggtatctccagcttatctggacaagaaattaaagttgtcaccagagtgggga acaacagaagctcccgagttccctggagagtttgtttctgaagacgaatataaaaggaag ctgagtgttcttatgcaagagctgttgatctcagaagaggattacattcaagatctacag ttcctccagactcatcaccttaagtacactgagacctgtcccaatgttccaggagctgtc gccagtcagagatccaccatcttcagaaatattgatgacattgctcgcttccattccagt gtcttcctccggggcttgcagaaatgtgacactgatgatgacgtggccatgtgctttatc aagcacgaagcagagtttaataagtacatccagtacctggtggggagggtacaggccgag tcgattgttgtcagcaaagctgtccaggatttctacaagagatacacagatgaaatttta actaatgaagatccttcacagccgcttatcccaccactgcagcactacctggaaaaaccc ataaacaggatccagcagtatcagactataatcaaggaattaatccgaaacaaagcaaga agtagccaaaactgcactttgctggagcaggcttacgctattgtgtctgccctcacccga agagcagaaaacaacctccatgtctcactcattgagaattatccgggcaccttggaaagc cttggtgaacccatacgacagggccacttcattgtgtgggaaggagctccaggagctaga atggcatggaaaggacacaaaagacatgtcttcctcttcaaaaattatattgtgatctgc aaaccaaagcgagacacaaagacagacacctacagttacatcttcaagaacatcatgaag ctgaacaacatagacgtgaatgaccttgtggaaggggatgaccgggcgtttgagatctgg catgaacgggaagacttggtccgcaagtacctccttcaggcacgtacagtgaatatcaag aactcctggttgaaggacatctgtggcatacagcagcggatcagcgagcctgtctggata cctccagactttgaggaagaactggcagattgtacagctgagctgggagagacagtcaag ctggcttgcaaagttacgggagctcccaagccatctgtcagctggtacaaagatggaaag cctgtggaggtggatccccatcacattataatagaagatcctgatggttcctgcactttg atcttggacaacctaacaggtgttgactcaggacagtacatatgcttcgcttccagtcct gctggaaatgccagtaccttaggaaagatacttgttcaagtgccaccaaggtttgtgaac aaggttagaaatgcttattttgtggagggtgaagatactcagtttacctgcactattgaa ggagcccctaggcctcagatcagatggtacaaagatggtctactgttgaaggacacaagt aaataccagactttcagtgaaccacggagtggtataatagtcctggtggtcaagaaccct tccaatgaagatatgggacactatgaatgtgagctggtgaacagattagggtctgcaaaa agtggagcagaactttaccaccacagtgctgcagccctgacccaggagaggagaggagac caagccattaccatagaaggaatgacttccccacagtcaaaggtggagactactgtccag gcctcacttcagcgtgctgataaggagatcaaaacagctctaaagaaactcgtggactcg gcatcactgctggtgactcttcccccgagcatgcaaggaggagccggtggccttggcctt cctgggtccattccttcagagcactcagaaagagcagctgggccctctgtcatagttcaa gaagccagtacccaaacccagactgctggaggtcatgacaaagcacaaagacagattcca gctgaagaaccaagcgtgccaaagtccagtcccggtctttcccgtgatgagacggctgct ggagatgaaaggactcaggagcgcaccgttcctattaccagaacatcaccagccgcgggg gcaggagactggtacagaagagaaggagatgtggtctgggacgtacacagtgaagtttat attgagaccacagaaagaactcgtgtgtataagactgaggagaagaccccaacaagtcct ccctatatgcaagtgacaatagaggatgtgcaggtgaattctggggagcgtgccaaattt caggcagtcattgaaggaacccctcagcctaccgttctgtggtttaagggcacttcgttg ctgacagacagcaccaggctccatcaagggaaggaaggaacaacgtatttcttagtcgtg gacaatgctgtctcagaagacggtggtgtttatacctgtgttgctaaaaatgcaggaggg gaggttttgtgcaaagcagagctaattgtacatgaagctaagaaagaccaagcagcaaag aaagtggccaccaggagaaagctccattccctttatgaggttaagcaggagattggaagg ggctgcttcagctttgtgaaacgagttgtacataaagggaacagggtgtcttgtgctgcc aaattcatacctctacgaagcaaaacgaaggctcgagcgcatcaagagagggatattctt gcctctctgtcccacgacagaattaccaggctcctggatcagtttgaaacacggaaaacg ctgattttgattctggagttatgctccagtgaagagctccttgaccgtttattcaagaag agtgtcgtcactgaagcagaggtcaaattatatatcaagcaaattttggaaggaatcaaa tatcttcatgacaacaacgtccttcatttggacattaagccgctgaatatcctcatggtt tatcctgaaagggaagaccttaagctctgtgactttggatttgcccagaagatcacgccc tttgagcctcagttcagcaaatatgggtctccggagttcgttgccccagaaattgtttct cggtcaccagtgtcaaaagcaaccgatatctgggctgtgggagtcatcacgtatttaagt ctaacgtgcaagtctccatttgctggggagaatgacagaggaacccttttaaatatccag aacggggaaatttcatggactattcctgattttgttcacttgagcgaagatgcaaaggac tttatgaaagggatcctacagcagcaccccgaagcaaggcctagtgctttggactgtctt tcccacaagtggttcatgcataatctccccctcgaagcagctcatttcattaataccaag cagctcaaattcattgtggctcggagcaagtggcagcggtctctgatgtgctataaatcc atactggtaatgcggtctatcccagaaatcctagaaagaactcatgacaacacctccctg gccatctcccgacatcttattgaagaaagcacttcatccagtaccagcggctcgtcttca gacaacgagaactcacatttccccaagaggcactttggctctacacccgaactgcacttg tccatatttgatgcatcaagccatcaggagcctccaaaaccctcaagtgaagagaagcac tctaaaatgtcagtccctccagtaaaacccatgaggaggaagtatgcttcaacgaaagct gaggtgggggacaaatcgcctacagaaaccaaagagctcatggcaagtatcttaaaggag aaagaggaggggctccatcccagacctcgagatgaaagagcagagcagtcccaaagaagc ggtgctgctgagtcttcatcagcgaggacttccacagaaagcacatcacatctctgtcag aaagaaaaaccagacatatttttatctgataaggacagaattgaaaaggctggggatggg acagaaaagccacctgtctgtgttcctagacagagtgtcattaaaagcactttctacagc caagcagctgagctacctgcaagggggccttcctcaccaggcagggagttcagaaggcac ctggacagagccagaaggactttccggaaagccggatattcaaaggtgcctctcagtggt ctccgtgagccccttctagagcagtttgaactggaagaagaagaaggaaagtctgatgat ggagatgatcacagggaaagtctgctgaccaaatcagcttcatttgacactgcaaggaaa ccaccacatcctgccattgctggtgctagccgaagccgttccctggatgactacaggctg agagcctcaagatcagtgagggaacaagatattttggaagaagactgtgatattttgtca caggaaagttgccctgaaggcagtgaccactgtgacatttctgcggggcctagcaaggga tgttctgtagacacttcaaagcaggaggactttaggagagccagcaaggattgttcagaa gagcagccccctccttccacaaaatgtgagggtaatgggtgcccagctgttactgtgcaa cagctagagagacttccagtgtcacctcataggagcgagaataggaaacatttactgaag aagtcaaaagctgcttactttgaggaggaagttgaagatttggaaggcaaaagcaccagt ctaactgcccagtgcttggacgtaactgcatcatcagctcaaaaacatgaaagcatggaa ggtaaatctccccctggcagtgcctctgacactgcttttcaggagggcaaacagtccatt tcaaccctcgcacagtcagacaccacctccaagtcagcccctacaagcaaggaaggtgca tatctgccccaggagtctgctcacagcaccgacatccagccggatctaaaaggtggaagc ttgcttatcaaaaggacagccccagttccaccttggaaagacgaaaggcacaaacattca catgagaagacttctgcccatagcgttgccaaatctgatctcatggagcatgaaagcact gctgttttaacaggcccacaaacagaaaccgattcacttccagtgtgtaaagacaaaagt caggaacttcctgatcaaagtgttccagtaactactgccttggtgggcaaacggcctggc accctaactgctctgcaaacagctgatgaaggtgtgcatcagaagctgaagacctatgaa gaggtgagatctggtgtcctggaggatgaaggaccaggtgttacagcaaccactccaccg tcagcccatgatggcgaaagccagacacacaagagggctcctgttcacggagacacagca tcagccaacctgaaggaagagcatcttgttgttccaaaagtcccaccaccaaaatcaatg ccaactttggtctccgatggagcacggcaggctgaaagggaacggccagctcatagcaag gagaggcttgctgctctgaggagggaaagctcagctgtcacagagcttgttcccagtttg gtccatgagactgaaatcgagggagctgaaccccagaaggtttctaaaggcagtggcatg gtgcctgctgttctggagagcagacacccagctagaactgcgtcttcccaaaatactggc ctcccttcggtccatgatagtgaacagcgagaacatccaaaggcatcacttcgcagtgag gtgagatcagctgtgacagcgagtggaagccaagcagctggacagactatgcctgctcct ttccccaaggctggacgtcaggtgtctgagcagcacagggctgcctgtcccagtggcaga gtttctgctgatctggagggtgggcctccaggtgtcttaactgcttcacaaccagaagtt gctccagctccagtctatgagctagaatttgaagagcatccaaagttgtatgatgagggt agaggcgttgccttagaaagtggaagctgtgatgctcgaagaactgtcccaccatcactc cacagggatcaaagtcaggagctctcacatcacaggtcgtctttttacagtgatgaggag tctgctgtgctggagggcttagtggatgagatggtttccctctctgaagagatgaatgtt tgggcagagtcagtttctggtgaggaagaatggagaaagcacatctctcctcccacagag atgttccacaaaggcccaggtagccaagcacctatggacaccgccttcccctctgtacaa gggggtaaaagagaagtttctgagctggatgaccttgcagaaccctatcctgccatgagt gagacgtcagtggtcctggaagggcagggaggacagatggttcctcatgaatgtgagcat ctggaagacttagcgtttgagagccccacttctagccaagtaagcgtttcctcaacagat agcttggatgctggaaaaagacccagtcaagtgtcagtaagcaaggacactggtaaacac ccagaagtttctttagtgaaaatcaaagacctgtcagatgaaacacccagtcttggcagt ggaactccaaaacttgacatatcagaggtagagcctgcctatttgaatttctctgacttg tatgacattgtctactttccatttgaatttctgaactacaggaaacctccacccaaacca actggtagacggtttataccttttggtgaaagggcaaggtcacctcctgcaggacatttg cataaggataaaagactgtgcatcagggaagaggcagaggacaggaacaggaagaaccat ttggaaatatctgaggattcaaaggcaactaacttattagccatggggaaaggatcagag agtcataaggaaatttatggccaccaaaaggactcaagtgggaagcagagaagctccttc tacaacaagccgggactctttaagccatatgcaaggtctcattcagtggagcagtcagtg gagcagagtctgaagaagaaagtaaaagcttctgttgcccatatttcaagaatcctaaaa ggaaagacatctcctgagccagaggaagagtttggcgagctgggaagcgaggcagttgaa aaagagctgttaacaggggctgaaggatctctgaagaggaaatccggactctcttcattc aagctatcaagcctcatgccaaaagagaaagcacctttgttcgttgaggagctcatcgat caggctgctgccgtcggacagtgcgtgacgctgtcgtgccggacggcagctcactcctcc ctgcacatcaactggttcagagatgggatacctgtccacagcagcagtcagatcctcatc tcagccacgctcaaaaacttccagctgttaactattctctctgttagtgccgacgatttt ggtatttacacctgtgtggccacaaactccttgggctcagcatctacctcttgcatcgta agaaaagcagagcttcctcccagccctccgtcccctgacatcgtggaagtctacgaggat ggagcgcaggtggcctggaaacctgtggaaacaaacatccccatccattacactgtgcag tgcaagagcgaagatggggagtggatgactcttgcttctgacatcgctgactgctgctac tacgccaaaaatctctccagggggtttatctactccttcaggatagcttgtaccagtaaa gcaggaatgggcccttacagcaacccatctgccaaagtgaaaatcactgggaaggatgaa atggagcttcgtgctgcaatgcagaacttcccaccagctgctgctgaagaagagagtgaa ataatcacaccatccgagcctttcccaacctaccagacctacgccttccaaacagagatc aaaagggggcgtttcagcatcgtccgacagtgcagggaaaaagtaagtggcaagacttta gctgctaaaattatcccttactggcaagaggacaagcagactgtgctcctcgagtaccaa atcctgcggaagcttcatcacacaaacatagctcagctgaagggagcctacgtcagccca cggcacttagtgttgatccaggagatgtgcgtgggaccggagctactccactctttggcg ttacggacatcatactcagaagtggaggtccgagattacctgtggcagaccctcagtgcc attgagtatctccatgcacacaacatcttgcacttggatctcaggtctgaaaacatgatc atcaccgagcccaacctgctgaaactcctggattttggcaatgcacagttctacccacaa gacaaagttattaccatggacaagtgcatggactatgttgaaacgatggctccagaactg ctgacagagcaaggagccctaccacagactgatatctggtccgtcggaatcacagccttc atcatgttgagtgccaactaccccgtcagctctgacgtagcctgtgagtttctgagaatg accaggaaggggaaagtgaagctcacgcggtgctacgcgggtctctccgggggagcagtg tcctttctccagagcacgctgtgtgcaaacccctggggaaggccatcagcctcagagtgc cttcagagcccgtggctccaggagacaggtttggacaacaggcagcaagcactggttacc ttccccaccaccaaactgaggaatttcctcactgaacgggaaaagaaaaggggcctgctg tgctccaagtatggcctcatgattgcacagtga

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