Grus americana (Whooping crane): 129206630 Help Entry 129206630         CDS       T11359                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism game  Grus americana (Whooping crane) Pathway game04020   Calcium signaling pathway game04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:game00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     129206630 (RYR3)    04020 Calcium signaling pathway     129206630 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:game04040]     129206630 (RYR3) Ion channels [BR:game04040]  Voltage-gated cation channels   Ryanodine receptor    129206630 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Other DBs NCBI-GeneID:  129206630 NCBI-ProteinID:  XP_054682161 LinkDB All DBs Position 5:complement(35648493..35890138) Genome browser AA seq 4873 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASVHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDDASEGAAQGGGHRTLLYGHAILLRHSFSEMYL TCLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER YLHLSISNGSIQVDASFMQTLWNVHPTCSGSNITEGYLLGGHVVRFFHGHDECLTIPSTD QNDSQHKKVLYETGGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGMYLALNED EGLAMLDREKSDTTSTAFCFRATKELKEKQDSSLKRDIDGMGVPEIKYGDSICFVQHVAS ALWLTYKAQDAKSARLAPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQ FTSGNNRTLSPAALPIEEMAQTLQDLITYFQLPEEDLEHEDKQSKLRSLKNRQNLFKEEG MLALVLNCIDRLNDYNSAAHFAGIAREDHGTAWKEILNLLYKLLAALIRGNRNNCTQFSS NLDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEDHIKSIISLLDKHGRNYKVLDV LCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW YFELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW SGRVPRAVASVNQHLLASDDVVSCCLDLGVPSISFRINGQPVQGMFENFSTEGFFFPVVS LSAGVKVRFLLGGRHGEFKFLPPGGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGT TQFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKR HHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHAHPAAEEDLKKVKLPKNYMMS NGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLV PYTLLDERTKKSNRDSLREAVRTFAGYGYSIEPPDQEITDQTVEKVSIDKIRFFRVEQSY AVKSGKWYFEFEAVTGGDMRVGWARPGCRPDVELGADDQAFVFEGSKGQRWHQGSGFFGR SWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGR MNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEIWRID GTIESPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFRSSFNFGMGVENASSDVFQKRKHS QEIAAPSTTYFYSLRIFAGQDPSSVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRV HESVKRSNCYMVWGGDVIANSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTCYQVE PNTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPV LWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFH YHTLKLYSSVSALGNTRVAYALCSHVDISQLFYTIDNQYLPGLLRSGFYDLLISIHLEHA KQAKLMMNNEFIIPVTDETRTIKLYPDETKKHGLPGVGLSTCLKPGFNFSTPCFIVTSEE RQTSSPEIPLDTLKSKAISMLTEAVQCSGTHIRDPVGGHVAFQFVPVLKLIATLLIMGVF DDDDVKQVLLLIDPNVFGDHKEETEERTEKEEVTQVEEKAVEAGEKAIKETKAPAKGLLQ TRLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQALNMSA ALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYEFHDDLLIHCGIPLEEEEE EEEDSSLTGKLCSLMYKIKGPPKAEKVEPKEEEEKSPTTLKELISQTMVRWSQEDQIQDP ELVRIMYTLLRRQYDSIGELLQALRKAYTISAASVKDTINLLAALGQIRSLLSVRMGKEE ELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQQIVFPKMVASCCR FLCYFCRISRQNQKAMFEHLSYLLQNSSVGLAFPSMRGSTPLDVAAASVMDNNELALALE EPDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENAS VVVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPTRDLPSQAYKREGDDDDAEEE IVHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPL KLSTVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASA SLDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRS LTKAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKY YCLPSGMGNYGIAAEEELHLTEKLFWGIFDSLSHKFLSLLQKYDPELFRMALPCLSAIAG ALPPDYLDTRIRSTLEKQTSMDPEGNFDPKPVSTANLVLPEKLEFIVSKYAEHSHDKWAF DKTNSGWKYGVSLDENMKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKE GGEALIHQRENEKLRSISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKK KKTELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVTGIIISRGLNDMELDAS SMEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHEQEIKFFAKVLLPLVDQY FTNHCLYFLSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDSATMVNCLH ILAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNI NYTTVALLPILTSIFEHISQYQFGIDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPA LGECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGL IKEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGSESVPQSAGPCCTMITSEHLS ILLGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIV MEEEQLRADSKSDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDE LFRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKSGGQDQERKKSKR RGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSYKDTDDEVKEHLRNNLH LQEKSDDPAVKWQLNLYKDILKSDEPTDPERNVERVQRISAALYHLEQVEQPLRSKKAVW HKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQNYWIETEEYSFEEKLVQDLATP PKKDEEEEEENEKKQPDPLHQIILYFSRSALIERSKLDDDPLYIAYSAMMAKSCQEEEEE EEEEEKEKTFEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHTGPMVVETLKLGIA ILNGGNTIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEG TLIVRERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYL LRLQESISDFYWYYSGKDVIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHS RLWDAVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQ MVDTLVESSSNVEMILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQKQY IQSEIEFLLSCAEADENDMFNYIDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQSL LEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESKRQFIFDVVN EGGEQEKMELFVNFCEDTIFEMQLASQISETDSSERPEEEEEAETCYVVDIGDDEEEEKS LESASAFAMACVAVKKNVANFFKMVTLKNLRKQYRKVRKMTVKEMVKVFFSFFWILFVGM FQLFFTIVWGIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDVMEAEKAEG TEHGIRAELVQFVKGEKGESDIISDIFGIHTKKEGGSKHGHDAGLGDIAEILGTDIQSSL ENTVRKKKGLQISEIAKEAETERKAEAEKADMEDGEKQDKAKEVQSEQLEEGKMKKKKRR HGQKIEKPEAVMANFFKALEIYQTKMLHYLARNFYNLRFLALFVAFAINFILLFYKVTEE PLDEVEEDSNLWNSFDEEEEEEGMVFFVLEESTGYMAPALRALAVVHTVISFVCVIGYYC LKVPLVVFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRK VINKYGDLYGAERIAELLGLDKSALDFSPVEESKPEEASLVSWLSSIDTKYHIWKLGVVF TDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLL AVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDP AGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIG NDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPA GDCFRKQYEDQLG NT seq 14622 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgttgccagcgttcacaaagaacaaaggaagttctgcttggcagct gagggacttgggaatcgcctgtgttttttggaaccaacatcagaagctaaatatgttcct ccagatctttgcatctgtaatttcgtcctcgaacagtccctatctgtcagagcccttcaa gaaatgttggccaatacaggggatgatgctagtgaaggggcagctcaagggggtggtcac agaaccctgctgtatggccacgctatactacttcgacattcgtttagtgaaatgtatttg acatgtttaacatcatcaagatcccagacggataaacttgcatttgatgtgggactacga gaaaatgcagcaggtgaggcatgctggtggacaatacaccctgcttctaaacaaaggtcg gaaggagaaaaagttcgaataggtgatgatcttatcctggtcagtgtgtcctctgaaaga tacctgcatctttccatatcaaatggaagtattcaagtggatgcctcctttatgcagacg ctgtggaatgtacatcctacgtgctcaggaagcaatattacagaaggatatcttcttggt gggcatgtagtacgttttttccatggccatgatgagtgtttgacaattccatctacagat cagaatgattcacagcacaagaaagtactttacgaaaccggaggagctggcgttcgagcg aggtctttgtggagagtagaaccccttcgaataagctggagtggaagtaacatcagatgg ggacagcctttccgtcttcgacatattacaacagggatgtacttggctctgaatgaagac gaaggacttgcaatgttagacagagaaaagtcggacacaacatctactgccttttgtttt agagcaacaaaggagctaaaagaaaagcaggattctagtcttaaacgtgacattgatgga atgggagtcccagagataaagtacggtgattcaatctgttttgtgcaacatgtggccagt gccttatggttgacttacaaagcacaagatgctaaatcagcacgtttagctcccttgaaa agaaaggttatattacaccaagaaggccatatggatgatggtctaactttacaaagatgt cagcacgaggaatcccaggctgctcgaatcattcgcaatactacaagcttattcagccag tttacaagtggaaacaacagaacactatcacctgctgccctgcctattgaggagatggct cagactctgcaagatctgattacttacttccagcttcccgaagaagacctggaacacgaa gataagcaaagcaagcttcggtcactcaaaaacagacaaaatctattcaaagaagaggga atgctggcactagttttgaattgcattgatcgcttaaatgactacaacagcgcagctcat tttgcaggaattgcaagagaagatcatggtacagcatggaaagaaattttgaatctcctt tacaaattgttagctgctctcatacgtggcaacagaaacaattgtactcagttttccagt aacctcgattggctaatcagtaaattggacagattagaatcttcctcaggtattttggaa gtgttgcattgcatcttgattgaaagcccagaagctttaaatataatagctgaggaccac ataaaatccattatttcattgttggataaacacgggcgcaattacaaggttctcgatgtg ctttgctctctctgtgtctgtaatggagttgcagttcgtgccaatcaaaatttgatctgt gacaatcttctgcctagaagagacttactcttgcaaacacgtttgattaatgatgtgaca agcataaggccaaacatatttttgggtgttgctgagggctctgcacaatacaagaagtgg tactttgagttaataattgatcaggtcgatccattcttgacggcagaacccacccattta cgagttggatgggcctctacttcaggttatgccccctatcctggaggtggagaaggatgg ggaggcaatggtgttggtgacgacctgtactcttatggttttgatggccttcatctgtgg tctggtcgagtacccagagctgtagcatctgtcaatcagcatttattagcatctgatgat gtggttagctgctgcttggatttaggtgtacccagcatttcattccgcattaatggacag cctgtacaaggaatgtttgagaacttcagtacagaaggatttttcttccccgttgtaagc ttatcagcaggtgtaaaagttcgtttcttattgggtggacgtcatggagagtttaaattt ctgcctcctggtggctatgctccctgttatgaagcattgcttccaaaagagaagatgaaa ctggaaccagtgaaagaatataagagagattctgatggagtgagggatctgctgggtaca actcagttcctctcccaagcttcctttatcccttgtccaatagacaccagtcagattgct cttccttttcatcttgaaaagatcagggacaaactggctgaaaatatccatgaactgtgg ggaatgaataaaatagaactgggctggacgtatggcaagatacgggatgataataaaaga catcatccttgtcttgtggaattctcaaaattacctgagacagagaagaattataatcta caaatgtcaactgaaacccttaagacccttttggcccttggatgtcacattgttcatgct catccagcagctgaggaagatcttaaaaaagtcaaacttcctaagaattacatgatgtca aatggatataaacctgcccctcttgatctttctgaagtgaaattgttaccttctcaagaa tttctagttgacaaactggcagaaaatgcacataatgtctgggcaaaagacagaataaag caaggatggacctatggcattcagcaggatcttaagaacaaacgtaatcctcggctagtg ccgtatacattattagatgaacgtactaaaaaatcaaacagagatagcctccgtgaagct gttagaacatttgcgggctatggctacagtattgagccacctgaccaagagataactgac caaacagtggaaaaagtcagcatcgacaagatacgatttttcagagtagaacagtcttat gcagtgaagtctggaaagtggtactttgaatttgaagctgtgacaggtggagacatgcgt gttggctgggccaggccaggctgtcgacctgacgtagagttgggagctgatgaccaagca tttgtatttgaaggaagcaaaggccagcgttggcatcaaggcagtgggttctttggacga agctggcagccgggagacgtggttggttgtatgataaacttggatgacaaatcaattatc tttactctgaatggagagttgcttataaccagtaaaggttcagaacttgcatttgctgac tttggaatagaaagtggttttgttccaatttgtgcactgggtctatctcagattggtcgt atgaaccttggaatggatgccagtacattcaagtattatacaatgtgtggccttcaagaa ggttttgaaccttttgctgtcaacatgaaccgagatgttgctatgtggtttagtaaacgc ttaccaacatttgtcaatgtgccaaaaaatcatcctcacattgagatatggagaattgat ggaaccattgagagtccacctcggttgaaagttactcacaaaacatttggcacacagaac agcaattcagacatgatatattgtcgtttgagcatgcccattgagttccgctcatcattc aacttcggcatgggtgtggaaaatgcctcatctgatgttttccaaaaacgaaagcacagc caagaaatcgctgctccttctactacgtatttttactcactacggatatttgctggccaa gacccctcctctgtctgggttggctgggtaacaccagactatcatttttacagtgagaat tttgacctaaataaaaattgtacagtgactgttactttaggtgatgagagaggcagggtt catgaaagtgtcaagcgcagcaattgctacatggtttggggaggagatgtaattgctaat tcccagagatcaggtcgcagtaatgttgatttagaaattggatgctttgttgacctggct actggaatgttgtcattcacagccaatggaaaagagcttggcacttgttatcaggttgaa ccaaacacaaagcttttcccagcaacctttgtacagcctacaagcactaatttggttcag tttgaacttggtaaattaaagaataccatgcctttatcagcagcaatttttaaaagtgaa gaaagaaatcctgttcctcagtgtccccctcgccttgacgtgcaaacaattacacctgtt ctgtggagcaggatgccaaacagctttctaaaagtagaaactgagcgcgtcagtgaacgt catggctgggttgtgcagtgtttggaacctctgcaaatgatggcacttcatatcccagaa gaaaacagatgtgttgatattttggaactatgtgaacaagaagatttgatgaagtttcac taccacactttaaaactgtatagctcagttagtgctctaggtaacactagagttgcttat gcactttgtagccatgtggacatatctcagctattttatacaatagataatcaatactta cctggactcctacgttctggattctacgacttgctcattagtattcatctggagcatgcc aagcaagccaagctcatgatgaacaatgaatttatcattccagttacagatgaaactcga actattaaattatatcctgatgaaacaaagaagcatggtttacctggggtagggcttagc acttgtctgaaaccaggctttaatttttctactccatgctttattgtgaccagtgaagaa cgtcagacatccagcccagagataccccttgatacacttaaatccaaggccataagtatg ttaacagaggcagtacagtgtagcggtactcatatacgagaccctgttggagggcacgtt gcattccagttcgttcctgttcttaaactgatagcaacattgctcataatgggtgttttt gatgatgatgatgtgaaacaggtattgctcctcattgatcccaatgtgtttggagatcac aaggaggaaacagaagagaggacagagaaggaagaagttacacaagttgaagaaaaagct gtagaagctggggagaaagcgataaaagaaacaaaagctcctgcaaagggcttattgcag acaagattaccagaatctgttaagcttcagatgtgtcatttactcaattatttctgtgac tgtgagctacaacatagagtggaagcaattgtatcatttgcagaccgttatgtatcaaaa ttgcaatataatcagaaatacaggtacaatgaactcatgcaagccttgaacatgtctgct gctttgactgccaaaaagactaaagaatttcggtctcctcctcaagaacagattaatatg ttactgaattttcaactgggagaggattgtccctgtccagaggagattcgggatgagtta tatgaatttcatgatgatcttctaattcactgtggtatcccactagaagaggaggaggag gaagaggaagattcctccttgactggcaaactctgttcattgatgtataaaatcaaaggt ccaccaaaagcagaaaaagtagaacctaaggaggaagaagagaaatctcctactacactg aaagaactcatatcccagactatggtgcgctggtcccaggaagatcagattcaagatcca gaattagttcgaattatgtacaccctccttcgtaggcaatatgacagcattggtgagcta ctgcaagctctgaggaaagcatacactattagtgctgcctctgtgaaggataccattaat ctgcttgcagcactgggccagattcgctcccttctcagtgtcaggatgggaaaagaggag gaattgctaatgattaatggattaggggatatcatgaacaacaaggtgttttatcagcat cctaacctaatgagagtcttgggtatgcatgagactgttatggatgtgatggtgaatgtg cttggaggagacaagtctcagcagatcgtttttcctaagatggtggcaagctgttgtcga ttcctgtgctacttctgtcgaattagtcgtcaaaaccaaaaggccatgtttgagcatctt agttacttactgcaaaacagcagtgttggactggcatttccttcaatgagaggttcaaca ccactagatgttgcagcggcctctgtaatggacaataatgagcttgcactagcattggag gagccagatctcgataaggttgtaacctacttggcgggttgtggcctgcagagttgtccg gtattgctggctaaaggatatccagacattggatggaatccaatagagggtgaacgttac ctgtcattcttaagatttgcagtatttgttaacagtgaaagtgttgaggaaaacgcaagc gttgttgtcaagctccttattcgacggccagagtgctttggaccagaccttaggggagag ggaggaaatggtttgctggcagctatgcaggaagctatcaggatctcagagaatcctact cgtgaccttccctcccaggcatataaaagagaaggtgatgatgatgacgcagaggaggag attgtgcacatgggcaatgcaatcatgtcattttactcagctctcatagatttacttgga cgctgtgcaccagaaatgcatcttattcaaagtggaaaaggggaagctattcgaatcagg tcaatccttcgatctctagtgccaactgaagatttggttgggattataagtataccacta aagctgtcaacagttaacaaagatggcacagtaaatgagccagacatgtctgcaaatttc tgtcctgatcataaagcacccatggtactctttttggaccgtgtctatggtattaaggac caaagcttcctccttcacctactggaagttggatttttaccagatttaagagcctctgcc tctttggatacagtttctttaagtaccacagaggcagctctcgcactaaatagatacatt tgctcagctgtgtttccattactcaagagatgtgctcccctcttttctggaacagagcat cacgcctctctggttgactccatgcttcacacaatatataggttatccaagggacgttcc cttacaaaagcacaaagagacactattgaagaatgcctgcttgctatttgccaccactta cgtccctctatgctacaacaactgttgagaaggctagtttttgatgtgcccctactcaat gaatactgtaaaatgcctctcaagcttctgacaaatcactatgagcagtgctggaaatat tattgtctgccttcaggaatgggaaactatggcattgcagcagaagaagaattacattta actgaaaaacttttctggggaatatttgattccttgtctcataagttcctatctctcctg cagaagtatgatccagagctctttcgaatggctttgccctgtctaagtgctatagctggt gctttgccccctgattatttagatacacgaattaggtcaacactggaaaagcagacttcg atggatccagaaggaaattttgatcccaaacctgtcagcacagcgaaccttgtacttcct gaaaagttggagtttattgtcagcaagtatgctgaacattcccatgataaatgggccttt gataagactaatagtggatggaagtacggtgtttcactggatgaaaatatgaagactcac ccattaataagacctttcaaaactttaactgaaaaggaaaaggaaatttatcgttggcct gccagagaatcactgaaaaccatgttggccatgggatggagcctagaaaggaccaaggaa ggaggagaagcactaatacatcagcgtgaaaatgaaaagctccgcagcatatctcagtct agccagggaaatgggtatagcccagcgccacttgatctctctaacgtggtgctttctagg gagcttcagggaatggttgaggtaatggcagaaaactaccataatatatgggccaaaaag aagaaaacggagttggaaagcaaaggtggaggtagtcatcctttattggtaccttatgac acgctgacagccaaggagaagtcacgggaccgtgaaaaggcacaggagctgttcaaattc cttcaggttactggtataatcatatctcggggactgaatgacatggagttggatgcttca tccatggaaaagaggtttgccttcaagtttctgaagaaaattttaaaatatgttgattct gctcaagagtttattgcgcatttggaagccattgtaaccagtggaaaaactgaaaaatct ccacatgaacaagaaataaaattctttgctaaagttcttttaccattagttgatcagtac tttacaaatcactgcctctacttcctgtcttctccaacaaaaacactcagtagcagtgga tatgcatcaaataaggaaaaggaaatggtagcaagcctgttctgcaaactagctgctctt gttagacataggatctcactttttggtagtgattctgctacaatggtaaactgcctgcac atcttagctcagtctcttgacacacgaactgttatgaaatcaggatctgagcttgttaaa gctggattgcgtgccttttttgaaaatgcagctgaagatctggaaaaaacttcagaaaat cttaaacttggaaagtttacccattcacgaactcaaatcaagggtgtttcacagaatatc aattatactacggtagcattgttgccgatcttgacatcaatttttgaacatatttcgcaa tatcagtttggaattgatttacttttgggtgacgtacaagtttcatgttacagaattctt tgtagcctctattctcttgggactgggaagaacatctatgttgaaaggcagcgtcccgca ctcggtgaatgcttagcatctcttgcagcagccattccagttgcatttcttgaaccttct ctcaaccattacaacccattgtctgtcttcaacacaaaaagtgcaagagaaagagcgatt ttaggtatgcctgatacagtagaagagatgtgtccagagattcctcagttggatggacta ataaaggaaattaatgatttagcagagtctggagcaaggtatactgaaatgcctcatgta attgaggttatcttacccatgctatgcaactatttatcctactggtgggaaagagggtct gagagtgttcctcaaagtgctggcccttgctgtacaatgataacatctgagcatctgagc atccttcttggaaacattctgaaaatcattaacaacaacctgggaatagatgaagcatct tggatgaaaagaattgcagtttatgctcaacccatcatcagcaaagccaggcctgatctg ctcaaaactcactttattccaacactggagaaattgaagaagaaagctataaagattgtg atggaagaggagcaactgagagcagatagtaaaagtgacacccaagaagctgagttactc attcttgatgagtttgctgttctttgtagagacctttacgccttctacccaatgttgata cgttatgtggacaacaacagagcgaattggctaaagaaaccagatgcagattctgatgaa ctctttcgaatggtagctgaagtttttatcctgtggtgtaaatcacataatttcaaaaga gaagaacaaaattttgtgattcagaatgaaatcaacaatttggcatttttaacaggagac accaagagcaagatgtctaaatctggaggacaagatcaagagagaaagaaatcaaaacgt agaggggatctatactccatacaaacatccttgattgtagctgcacttaaaaagatgctt cctattggtttgaatatgtgtactcctggagatcaagagctcatctctttggctaagact agatacagctataaggacactgatgatgaagtcaaagaacatctacgtaacaacttacat ttgcaggaaaagtctgatgatccagctgtgaaatggcagttaaatctgtacaaagacatt ttgaagagtgatgaacctacagaccctgagagaaatgtggaacgtgtgcagaggatatca gctgctctgtatcatctggaacaggttgaacagccactgagatcaaagaaagctgtttgg cacaaactcctgtcaaaacaacgcaaaagggctgttgttgcgtgtttcagaatggcacca ctatacaacctgccaaggcaccgttctattaacctcttcctccatggctatcagaactat tggatagaaacagaggaatattcatttgaggagaaactagttcaggatttggctacacct ccaaaaaaagatgaagaggaagaggaagagaacgagaaaaaacagcctgatccacttcat cagattatcctctatttcagtcgcagcgctctcatagagagaagcaaactagatgatgat cctttatatattgcctattccgccatgatggcaaagagctgtcaggaagaagaagaagag gaagaagaagaagaaaaagaaaagacatttgaggagaaagaaatggaaaagcagagaact ctctatcagcaagctcgcttacatgatcgtggagctgctgagatggtcctacagatgatt agtgcaagcaaaggtcatacaggacccatggttgttgaaacactaaaacttggtattgct attctaaatggtgggaataccatagttcaacagaaaatgctagactacctgaaggagaaa aaggatgctggattttttcaaagtctgtctggcttgatgcagtcctgcagcgttcttgac ttgaatgcgtttgagagacaaaataaagcagaaggcctgggaatggttactgaagaagga actctcatcgttcgtgagcgtggtgaaaaagtgttgcagcatgatgaatttactcgagat ctgtttagatttttacaactgctctgtgaagggcataacaatgattttcaaaattaccta cgtactcagatgggcaacaccacgaccgtgaatattatcattagtacagtggactatctc ttgcgacttcaggaatcaatcagcgacttctattggtactattcaggaaaggatgtcatt gatgaatcagggcaacgtaacttctctaaagctttggctgtcaccaaacaaatattcaat tcccttacagaatatatccagggcccttgcataggtaatcaacagagtctggctcatagt aggctatgggatgcagttgttggctttcttcatgtctttgccaatatgcagatgaaactt tcacaggactctgctcagattgaattgcttaaagagctactagatctgctaaaggatatg gtagtgatgctcttgtcactgcttgaaggtaacgttgtaaatggaactattggaaaacaa atggtagacacgctcgtagaatcatctagcaatgtagaaatgattttgaagttctttgac atgttcctcaagttaaaagatctgactaactcagatgctttcaaagagcatgacccagat ggtaaaggcataatttcaaagaaggaattccagaaatcaatggaggctcaaaaacaatac atacagtcagagattgaattcctgctgtcctgtgcagaagctgatgaaaatgatatgttt aactatattgattttgtggaaagattccatgaaccagccaaagacattggatttaatgta gcagtattgctaacaaacctttcagagcacatgcctaatgattcacgccttcagagctta cttgaacctgcggagagtgttcttaattactttgaaccgtaccttggccgtattgagata atgggtggagccaagaaaatagaaagagtttactttgaaatcagtgaatccagtagaatg cagtgggagaagccgcaggtgaaggaatccaaaaggcagttcatatttgatgttgtaaat gaaggaggagagcaagaaaaaatggaactctttgtgaatttctgtgaagacacgatcttt gaaatgcagttagcatcccagatctctgaaacggattcatctgagaggcctgaggaagag gaagaagcagagacttgttatgtagtagatattggagatgatgaggaagaagaaaagtcc ctggaatctgcatcagcttttgcaatggcctgtgttgcagtgaagaagaatgttgccaac ttttttaaaatggtcactctgaagaacctaaggaaacaatacaggaaagttagaaagatg acagtaaaagagatggtgaaagtgtttttctcctttttctggatcttattcgtagggatg tttcaactgttctttactatagtgtggggaattttccagattctttggagcactgtattt gggggtggcctggttgaaggagccaaaaacattaaagttactaaaatattgggagacatg cctgacccaacacagtttggaatccatgatgatgttatggaagcagaaaaagctgaaggc actgagcatggcatcagagctgaacttgtgcagtttgtgaagggtgagaagggagaaagt gacatcatctcggacatttttggcattcatacaaagaaagaaggtggctcaaaacatgga cacgatgctggacttggagatattgcagaaatccttggtactgatatccagtcatctttg gaaaacacagttcgtaagaaaaaaggattacagatatctgaaattgcaaaagaagctgaa acagaaagaaaagcagaagctgagaaggctgatatggaagatggtgagaaacaagacaaa gcaaaggaagtacaatctgagcagctagaagagggaaaaatgaagaaaaagaagcgaagg catggacaaaaaattgagaaaccggaggctgttatggctaacttcttcaaagctttggaa atttatcaaacaaaaatgcttcactacttggcaagaaatttttataacttaagatttctt gctctatttgttgcatttgccatcaactttattcttctattttacaaggtgacagaagag cctcttgatgaagtagaggaagactcgaatctctggaactcttttgatgaagaggaagag gaggagggcatggtgttttttgttttagaagaaagcacaggttacatggcacctgctctc agagcactggcagttgttcatactgtcatctcctttgtctgtgtgatcggatactactgt ttaaaggtccctctggttgtattcaagagagaaaaggaggtagctagaaagctggaattt gatggactatacataactgaacagccatctgaagacgatattaaaggacaatgggatcgc ctggttataaacactccgtcctttccaaacaattactgggacaaatttgtaaaacggaag gttattaacaaatatggagacttatatggagcagagcgcatagcagaacttttgggtttg gacaaaagtgcccttgattttagtccagtggaagagagcaaaccagaagaggcgtctctt gtatcatggttaagctccattgatacaaagtaccacatttggaagctcggagttgttttc actgataattcgtttttatacttagcttggtacacgactatgtccatccttgggcactac aacaacttcttctttgctgctcatctgctggatattgctatgggtttcaagacactacga accattttgtcttcagtcactcacaatggcaaacagcttgtgcttactgtgggactcctc gctgtagtagtgtatctttacactgttgtggcgttcaacttcttccgcaaattctacaat aaaagtgaagatgaagatgaaccagacatgaaatgtgatgacatgatgacgtgttacctg ttccatatgtatgtgggcgtgagagctggtggcggcattggagatgaaattgaggatcct gctggagacccttatgaaatgtatcgaattgtctttgacatcacatttttcttctttgtc attgttatcctactggccattattcaaggtctgattattgatgcttttggtgaattaaga gaccagcaagaacaagtgagagaagatatggagaccaaatgttttatttgtggaatcggc aatgactattttgacacaaccccacatggctttgaaacacatactttgcaagaacacaac ttggcaaactacctgttctttttaatgtatctcattaacaaggatgaaactgagcatact ggccaggagtcatttgtgtggaagatgtaccaagaaagatgttgggattttttcccagca ggggactgcttccggaaacagtatgaggatcaacttggctaa

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