KEGG   Gracilinanus agilis (agile gracile opossum): 123233417
Entry
123233417         CDS       T07702                                 
Symbol
IKBKB
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit beta
  KO
K07209  inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas01523  Antifolate resistance
gas04010  MAPK signaling pathway
gas04014  Ras signaling pathway
gas04062  Chemokine signaling pathway
gas04064  NF-kappa B signaling pathway
gas04068  FoxO signaling pathway
gas04150  mTOR signaling pathway
gas04151  PI3K-Akt signaling pathway
gas04210  Apoptosis
gas04380  Osteoclast differentiation
gas04620  Toll-like receptor signaling pathway
gas04621  NOD-like receptor signaling pathway
gas04622  RIG-I-like receptor signaling pathway
gas04623  Cytosolic DNA-sensing pathway
gas04625  C-type lectin receptor signaling pathway
gas04657  IL-17 signaling pathway
gas04658  Th1 and Th2 cell differentiation
gas04659  Th17 cell differentiation
gas04660  T cell receptor signaling pathway
gas04662  B cell receptor signaling pathway
gas04668  TNF signaling pathway
gas04722  Neurotrophin signaling pathway
gas04910  Insulin signaling pathway
gas04920  Adipocytokine signaling pathway
gas04930  Type II diabetes mellitus
gas04931  Insulin resistance
gas04932  Non-alcoholic fatty liver disease
gas04936  Alcoholic liver disease
gas05010  Alzheimer disease
gas05132  Salmonella infection
gas05135  Yersinia infection
gas05142  Chagas disease
gas05145  Toxoplasmosis
gas05160  Hepatitis C
gas05161  Hepatitis B
gas05162  Measles
gas05163  Human cytomegalovirus infection
gas05164  Influenza A
gas05165  Human papillomavirus infection
gas05166  Human T-cell leukemia virus 1 infection
gas05167  Kaposi sarcoma-associated herpesvirus infection
gas05168  Herpes simplex virus 1 infection
gas05169  Epstein-Barr virus infection
gas05170  Human immunodeficiency virus 1 infection
gas05171  Coronavirus disease - COVID-19
gas05200  Pathways in cancer
gas05206  MicroRNAs in cancer
gas05208  Chemical carcinogenesis - reactive oxygen species
gas05212  Pancreatic cancer
gas05215  Prostate cancer
gas05220  Chronic myeloid leukemia
gas05221  Acute myeloid leukemia
gas05222  Small cell lung cancer
gas05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
gas05417  Lipid and atherosclerosis
gas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123233417 (IKBKB)
   04014 Ras signaling pathway
    123233417 (IKBKB)
   04064 NF-kappa B signaling pathway
    123233417 (IKBKB)
   04668 TNF signaling pathway
    123233417 (IKBKB)
   04068 FoxO signaling pathway
    123233417 (IKBKB)
   04151 PI3K-Akt signaling pathway
    123233417 (IKBKB)
   04150 mTOR signaling pathway
    123233417 (IKBKB)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    123233417 (IKBKB)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123233417 (IKBKB)
   04621 NOD-like receptor signaling pathway
    123233417 (IKBKB)
   04622 RIG-I-like receptor signaling pathway
    123233417 (IKBKB)
   04623 Cytosolic DNA-sensing pathway
    123233417 (IKBKB)
   04625 C-type lectin receptor signaling pathway
    123233417 (IKBKB)
   04660 T cell receptor signaling pathway
    123233417 (IKBKB)
   04658 Th1 and Th2 cell differentiation
    123233417 (IKBKB)
   04659 Th17 cell differentiation
    123233417 (IKBKB)
   04657 IL-17 signaling pathway
    123233417 (IKBKB)
   04662 B cell receptor signaling pathway
    123233417 (IKBKB)
   04062 Chemokine signaling pathway
    123233417 (IKBKB)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123233417 (IKBKB)
   04920 Adipocytokine signaling pathway
    123233417 (IKBKB)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    123233417 (IKBKB)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123233417 (IKBKB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123233417 (IKBKB)
   05206 MicroRNAs in cancer
    123233417 (IKBKB)
   05208 Chemical carcinogenesis - reactive oxygen species
    123233417 (IKBKB)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    123233417 (IKBKB)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    123233417 (IKBKB)
   05221 Acute myeloid leukemia
    123233417 (IKBKB)
   05220 Chronic myeloid leukemia
    123233417 (IKBKB)
   05215 Prostate cancer
    123233417 (IKBKB)
   05222 Small cell lung cancer
    123233417 (IKBKB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123233417 (IKBKB)
   05170 Human immunodeficiency virus 1 infection
    123233417 (IKBKB)
   05161 Hepatitis B
    123233417 (IKBKB)
   05160 Hepatitis C
    123233417 (IKBKB)
   05171 Coronavirus disease - COVID-19
    123233417 (IKBKB)
   05164 Influenza A
    123233417 (IKBKB)
   05162 Measles
    123233417 (IKBKB)
   05168 Herpes simplex virus 1 infection
    123233417 (IKBKB)
   05163 Human cytomegalovirus infection
    123233417 (IKBKB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123233417 (IKBKB)
   05169 Epstein-Barr virus infection
    123233417 (IKBKB)
   05165 Human papillomavirus infection
    123233417 (IKBKB)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123233417 (IKBKB)
   05135 Yersinia infection
    123233417 (IKBKB)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123233417 (IKBKB)
   05142 Chagas disease
    123233417 (IKBKB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123233417 (IKBKB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123233417 (IKBKB)
   05418 Fluid shear stress and atherosclerosis
    123233417 (IKBKB)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    123233417 (IKBKB)
   04936 Alcoholic liver disease
    123233417 (IKBKB)
   04932 Non-alcoholic fatty liver disease
    123233417 (IKBKB)
   04931 Insulin resistance
    123233417 (IKBKB)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    123233417 (IKBKB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gas01001]
    123233417 (IKBKB)
Enzymes [BR:gas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     123233417 (IKBKB)
Protein kinases [BR:gas01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   123233417 (IKBKB)
SSDB
Motif
Pfam: IKBKB_SDD Pkinase PK_Tyr_Ser-Thr Kdo Pkinase_fungal ubiquitin ABC1 APH YrbL-PhoP_reg Spectrin_SYNE1_2 Glyco_hydro_65m TBK1_ULD
Other DBs
NCBI-GeneID: 123233417
NCBI-ProteinID: XP_044515467
LinkDB
Position
2:complement(165853859..165932308)
AA seq 568 aa
MSWPPSLQMQTCGPWEMKERLGTGGFGNVIRWHNEETGEQIAIKQCRQELSLRNRERWCL
EIQIMRRLNHPNVVAARDVPEGMQKLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREE
AILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRLIHKIIDLGYAKELDQGSLCT
SFVGTLQYLYKLKRDIPRSQKYLVFDSKDIKLFLSQAGQSILAQRLEKWLQLMLMWQPRQ
RGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTVHTYPIMEKESLQSLKARIQADTGIP
EEDQELLQEAGLALFSDKPATQCIVDSKLNDDRILDMDLIFLFDNRKITYETQISPRPPP
ESVSCILQEPKRNLPFFQLRKVWGQVWHTIRTLKEDCSQLQQGQRAAMMNLLRNNSSLSK
MKNLMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRE
SDVKLLVEQMMALQTDIVDLQRSPMSRKQGGTLDDLEEQARELYRRLREKPRDQRTDGDS
QEMVRLLLQAIQSFEKKVRAIYMQLRYK
NT seq 1707 nt   +upstreamnt  +downstreamnt
atgagctggcccccttctcttcaaatgcagacttgtgggccctgggagatgaaagaacgc
cttggaactgggggatttgggaacgtcatccgatggcacaatgaggaaacaggagagcag
atcgccatcaaacaatgtcggcaggagctgagtcttcggaatcgagagagatggtgtcta
gaaatacaaatcatgagaagacttaaccatcccaatgttgtcgctgcccgggatgtccct
gaagggatgcagaagctggcgcccaatgaccttcctctgctggctatggaatattgtcag
ggcggagacctccgaaagtacctgaaccagtttgagaactgctgtggcctccgggaagaa
gccatcctcactctactttctgacattgcctcggcactcagataccttcatgaaaatcgg
atcatccatcgggacctgaagcctgaaaacatcgtcctacaacaaggagaaaaaaggtta
atacacaagatcattgacctaggatatgctaaagaactggatcaaggcagtctttgtact
tcttttgtggggacactgcaatacctgtacaaactcaaaagagacatccccagatcccaa
aaatacttggtatttgatagtaaagacattaagttatttctgtctcaagcaggtcaaagt
atactagcccagcgattagaaaagtggctgcagctgatgttaatgtggcagccccgtcag
aggggcacagaccctacgtatggcccaaatggctgtttcaaagccctggatgacatcttg
aacctaaagctggttcacatcttgaatatggtaacaggcaccgtgcacacctaccccatc
atggagaaagaaagcttgcaaagcttgaaggccaggatccaggccgacacgggcatccca
gaagaggaccaggagctgctccaggaggctggcctggcattgttctccgacaaaccagcc
acgcagtgtattgtagatagcaagctaaacgatgaccgaatattggacatggacctcatt
tttctctttgacaatagaaaaatcacctatgagactcagatctccccgaggcccccacca
gaaagtgtcagctgtatccttcaagagcccaagcggaatctcccttttttccagctgagg
aaagtgtggggtcaggtgtggcacacgatccggaccctgaaagaagattgcagccagctg
cagcaaggccagagagcagctatgatgaatctccttcgcaataatagcagcctctccaaa
atgaagaatttaatggcatccatgtctcagcagctcaaggctaaactggatttctttaaa
accagcatccagattgacctggagaaatatagtgaacagaccgagtttggcatcacatcg
gataaactgctgctggcctggcgggagatggagcaggctgtggagctctgcgggcgggaa
tcagatgtgaaacttctggtagaacaaatgatggcactacagacagacattgtagaccta
cagaggagcccaatgagtcggaaacaaggaggaaccttggatgatctagaagaacaagca
agagagctttaccggcgactaagagaaaaaccaagagaccagcgaactgatggtgacagt
caagaaatggttcgactacttctacaggccatccagagctttgagaagaaagtacgagcc
atttatatgcagctcaggtataaataa

DBGET integrated database retrieval system