Gracilinanus agilis (agile gracile opossum): 123234414
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Entry
123234414 CDS
T07702
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00760
Nicotinate and nicotinamide metabolism
gas01100
Metabolic pathways
gas04068
FoxO signaling pathway
gas04148
Efferocytosis
gas04152
AMPK signaling pathway
gas04211
Longevity regulating pathway
gas04213
Longevity regulating pathway - multiple species
gas04218
Cellular senescence
gas04310
Wnt signaling pathway
gas04922
Glucagon signaling pathway
gas04936
Alcoholic liver disease
gas05031
Amphetamine addiction
gas05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
123234414 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
123234414 (SIRT1)
04068 FoxO signaling pathway
123234414 (SIRT1)
04152 AMPK signaling pathway
123234414 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123234414 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
123234414 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
123234414 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
123234414 (SIRT1)
04213 Longevity regulating pathway - multiple species
123234414 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
123234414 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
123234414 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123234414 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
gas03036
]
123234414 (SIRT1)
03029 Mitochondrial biogenesis [BR:
gas03029
]
123234414 (SIRT1)
Enzymes [BR:
gas01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
123234414 (SIRT1)
Chromosome and associated proteins [BR:
gas03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
123234414 (SIRT1)
Mitochondrial biogenesis [BR:
gas03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
123234414 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
123234414
NCBI-ProteinID:
XP_044516252
LinkDB
All DBs
Position
2:complement(700608752..700635762)
Genome browser
AA seq
708 aa
AA seq
DB search
MHTDLRPAVHTLLPGGPLGQTSTPPTAPMRRGLGAVPKFSCLRTRGQWQAGKLAAPLAPG
AASGSPAWYHQGGSQALRVGSNEFPEMEAGETAPGSYFGSSQQRACAPRVYFAENLFSDE
TLANGFHSCDSDEDDRASHASSSDWTPRPRTGPYTFVQQHLMIGTDPRTILKDLLPETIP
PPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKIIVLTGAGVSVSCGIP
DFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAKEIYPGQFQPSLCHKFIA
LSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLICKYKVDSEAVREDIFNQV
VPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI
PSSIPHEVPQILINREPLPHLHFDVELLGDCDVIIHELCQRLGGEYARLCPSPTRLSEIT
EKPPRPQREPGARWLALPPTPLNVSEDSSSPGRTSPPDSWAGDRRAGEPDDGATSRGGCR
AEKPPPEGRVPSGPPASITEQLEEAGANGGEKNERTHVVETLRKCWPNRLAKEQISKRLD
GNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCGSNSDSGTCRSPSLEEPMEDESEMEEF
YNGLEEDADAPDRGGPGCGCEKDDQRAASEAASGKDEAAAVDHSSSRL
NT seq
2127 nt
NT seq
+upstream
nt +downstream
nt
atgcatacggatctgcgtcccgctgtccacacgctgctacccggaggcccgctgggccaa
acctcgactcctcccacagcccccatgcggagggggctcggggccgttcctaagttctcc
tgtttgaggactcggggacagtggcaggcagggaagctggcggctcccctcgcccccggg
gcggcctcgggctccccagcttggtaccaccaagggggttcacaggcgctgcgggttggg
tcaaacgagttcccggagatggaggcaggagagactgctcccggctcctacttcggcagc
tcccagcagagggcttgtgctcccagagtctattttgcagaaaatctcttcagtgatgaa
actcttgccaatggctttcattcctgtgacagtgacgaggatgaccgtgcctctcatgca
agctccagtgactggactcccagacctagaacaggtccttacacatttgtgcagcaacat
ctcatgatcggcacagatcctcggacgatcctgaaggatctgctgccagaaacaatccca
ccacctgagctagatgatatgactctctggcagattgttatcaacatcctttcagaacca
ccaaaaaggaaaaagagaaaagatattaatacaattgaggatgctgtgaagttattgcag
gagtgcaaaaagatcattgttctcactggagctggggtatctgtttcctgtggaatacct
gacttcagatcaagagatggtatttatgctcgactggcagtagattttcccgacctccct
gatcctcaagcaatgtttgacattgaatatttcagaaaggatccaagaccatttttcaag
tttgcaaaggaaatctatcctgggcaattccagccatctctctgccataaatttatagcc
ttgtcggataaagaaggaaaactacttcgaaactacactcagaacatagatacactggaa
caagttgcggggatacagaggataattcagtgtcatggttcctttgcaacagcttcttgc
ttgatttgtaaatacaaggtggattctgaagctgtacgtgaagatatatttaatcaggtg
gttcctcgctgtccccggtgtcctgccgatgagccacttgccatcatgaagccagagatt
gtattctttggggaaaacttaccagagcagtttcacagagccatgaagtatgacaaggat
gaagtcgatctcctcattgttattgggtcttccctgaaagtaagaccagtagcgctgatt
ccgagttccattccccacgaagtgcctcagatcctgatcaacagggaacccctgcctcac
ctgcactttgacgtcgagcttctgggggactgtgacgtcatcatccacgagctctgccag
cggctgggcggcgagtacgcccggctctgccccagcccgacgaggctttcggagatcacg
gagaagcccccgcggccccagagggagccgggcgcccgctggctggcgctgccgcccacc
cccctcaacgtctccgaagactctagttcccccggcagaacttccccgccagactcttgg
gcgggcgacaggagggccggggagcccgacgacggggccacctcccgggggggctgccga
gcggagaagccgccgccggagggccgagtgccttcggggccccccgcgagtatcacagag
cagctggaggaggccggagccaacggtggggagaaaaacgaaagaactcacgttgtggag
accctgaggaagtgctggcccaaccggctcgccaaagagcagatcagtaagcggctcgac
ggtaaccagtacctctttttaccaccaaatcgctatatttttcatggcgccgaggtgtac
tcggactctgaagacgacgtcctgtcctccagctcttgtggcagcaacagcgacagcggc
acgtgccggagccccagcctcgaggagcccatggaggacgagagcgagatggaggaattc
tacaacggcctggaggaggacgccgacgctccggacagaggcggccccggctgcggctgc
gagaaagacgaccagcgcgcggccagcgaagccgcgtccggcaaggacgaggccgccgcc
gtcgaccattcgtccagcaggttataa
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