Gracilinanus agilis (agile gracile opossum): 123237042
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Entry
123237042 CDS
T07702
Symbol
PLCG2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas00562
Inositol phosphate metabolism
gas01100
Metabolic pathways
gas01521
EGFR tyrosine kinase inhibitor resistance
gas04012
ErbB signaling pathway
gas04014
Ras signaling pathway
gas04020
Calcium signaling pathway
gas04062
Chemokine signaling pathway
gas04064
NF-kappa B signaling pathway
gas04066
HIF-1 signaling pathway
gas04070
Phosphatidylinositol signaling system
gas04072
Phospholipase D signaling pathway
gas04360
Axon guidance
gas04370
VEGF signaling pathway
gas04380
Osteoclast differentiation
gas04517
IgSF CAM signaling
gas04611
Platelet activation
gas04613
Neutrophil extracellular trap formation
gas04625
C-type lectin receptor signaling pathway
gas04650
Natural killer cell mediated cytotoxicity
gas04662
B cell receptor signaling pathway
gas04664
Fc epsilon RI signaling pathway
gas04666
Fc gamma R-mediated phagocytosis
gas04670
Leukocyte transendothelial migration
gas04722
Neurotrophin signaling pathway
gas04750
Inflammatory mediator regulation of TRP channels
gas04919
Thyroid hormone signaling pathway
gas04933
AGE-RAGE signaling pathway in diabetic complications
gas04935
Growth hormone synthesis, secretion and action
gas05167
Kaposi sarcoma-associated herpesvirus infection
gas05169
Epstein-Barr virus infection
gas05170
Human immunodeficiency virus 1 infection
gas05171
Coronavirus disease - COVID-19
gas05200
Pathways in cancer
gas05205
Proteoglycans in cancer
gas05206
MicroRNAs in cancer
gas05214
Glioma
gas05223
Non-small cell lung cancer
gas05225
Hepatocellular carcinoma
Module
gas_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
123237042 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
123237042 (PLCG2)
04014 Ras signaling pathway
123237042 (PLCG2)
04370 VEGF signaling pathway
123237042 (PLCG2)
04064 NF-kappa B signaling pathway
123237042 (PLCG2)
04066 HIF-1 signaling pathway
123237042 (PLCG2)
04020 Calcium signaling pathway
123237042 (PLCG2)
04070 Phosphatidylinositol signaling system
123237042 (PLCG2)
04072 Phospholipase D signaling pathway
123237042 (PLCG2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
123237042 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123237042 (PLCG2)
04613 Neutrophil extracellular trap formation
123237042 (PLCG2)
04625 C-type lectin receptor signaling pathway
123237042 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
123237042 (PLCG2)
04662 B cell receptor signaling pathway
123237042 (PLCG2)
04664 Fc epsilon RI signaling pathway
123237042 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
123237042 (PLCG2)
04670 Leukocyte transendothelial migration
123237042 (PLCG2)
04062 Chemokine signaling pathway
123237042 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
123237042 (PLCG2)
04919 Thyroid hormone signaling pathway
123237042 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
123237042 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123237042 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
123237042 (PLCG2)
04380 Osteoclast differentiation
123237042 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123237042 (PLCG2)
05206 MicroRNAs in cancer
123237042 (PLCG2)
05205 Proteoglycans in cancer
123237042 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
123237042 (PLCG2)
05214 Glioma
123237042 (PLCG2)
05223 Non-small cell lung cancer
123237042 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
123237042 (PLCG2)
05171 Coronavirus disease - COVID-19
123237042 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
123237042 (PLCG2)
05169 Epstein-Barr virus infection
123237042 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
123237042 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
123237042 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
gas04131
]
123237042 (PLCG2)
Enzymes [BR:
gas01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
123237042 (PLCG2)
Membrane trafficking [BR:
gas04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
123237042 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
123237042 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
EF-hand_PLCG2
C2
SH3_1
SH3_9
PH
PH_12
SH2_1
EF-hand_PLCG1
SH3_2
PH_14
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
123237042
NCBI-ProteinID:
XP_044519585
LinkDB
All DBs
Position
2:complement(217426866..217599304)
Genome browser
AA seq
1264 aa
AA seq
DB search
MTTKINIDTLPEYEKSQIKRTLELGTVMTLFSLKKSNPERRTVQVITETRQVAWSKTADK
IEGFLDLMEIKEIRPGKNSKDFERGKASRQKEDCCFTIFYGTQFVLNTLSLAADSKEDAS
KWLCGLTILHQEAQNASTPTITESWLRKQIYSVDQTRRNSISFRELKAILPLVNFKVSSA
KFLKDKFLEIGAYKDELSFEQFHLFYKKMMFDQQKSILDEFKKDSSVFILGNTDRPDASA
VHLHDFQRFLMHEQQETWAQDLSKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSKENS
IWDDKYDSVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTESYIRCLRMGCRCIELDC
WDGPDGKPIIYHGWTRTTKIKFDDVVQAIRDHAFVSSQFPVILSIEEHCCVEQQRHMARV
FKEVFGDLLLTRPTEASADQLPSPAQLKEKIIIKHKKLGPRGDVDINIEDKKEEKKQQGE
LYMWDTIDQKWYRHYCAIADEKLSFSDDIEQNMEEDSVKDVAQTDLHFGEKWFHKRMEKR
TSAEKLLQEYCAETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTPEGGTMKYY
LTDNLMFNSIYDLIQHYREAHLRCAEFELRLTDPVPNPNPHESKAWYYDSLSRGEAEDML
MRIPRDGAFLIRKREGGDAYAITFRAKGKVKHCRINKDGHHFVLGTSAYFESLVELVSYY
EKHALYRKMRLRYPVTPELLERYNTERDINSLYDVRMYVDPSEINPSTPQRTVKALYDYK
AKRRDELSFCRGALIHNVSKEPGGWWKGDYGGRIQQYFPSNYVEDISTVDFEELEKQIIE
DNPLGSLCRGILDLNTYNVVKVPHGKNQKSFVFILEPKNPNDPPVEFATDKVEELFEWYQ
SIREITWKNATVETNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVET
KADSIVRQKPIDLLKYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGAQMVALNFQTADKYM
QLNHALFALNGRTGYVLQPESMRNENYDPTPLESQRKILMTLTVKVLGARHLPKLGRSIA
CPFVEVEICGTEYDNNKFKTTVVNDNGLSPVWASTQEKVTFEIYDPNLAFLRFVVYEEDM
FSDPNFLAHATYPIKGIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLECEEELYSSCR
QLRRRQEELNNQLFLYDTHQNIRNANRDALVNEFNVNENQLQLYQEKCNRRLREKRVSNS
KFYS
NT seq
3795 nt
NT seq
+upstream
nt +downstream
nt
atgaccaccaagatcaacatagacacccttcccgaatatgagaagagtcagatcaagcgg
actctggaattgggaactgtcatgaccttgtttagcctcaagaagtctaaccctgagagg
agaacggtccaggtcatcacagagaccagacaggtggcctggagtaagacggctgacaag
atcgaaggattcttggacttgatggagataaaggaaatccgtccagggaaaaattcaaaa
gactttgaacgtgggaaagcaagtcgccagaaagaagattgctgcttcaccatattttat
ggcactcagtttgtcctcaacaccctgagtttagcagctgactccaaggaagatgctagt
aaatggctttgtggcttgacaattttgcaccaagaagcccagaatgcctcaacaccaact
attaccgagagttggctaagaaagcaaatttattctgtagaccaaactcggagaaatagt
atcagcttccgagaactgaaggccattcttcctttagtaaacttcaaagttagcagtgcc
aagttcctgaaggacaaattcctggaaataggtgcctacaaggatgaactcagctttgaa
cagttccacttattctacaaaaagatgatgtttgatcaacagaaatcaattcttgatgag
ttcaaaaaagattcatctgtgtttattctgggaaatacagaccggccagatgcatctgcc
gttcacttgcatgatttccagaggtttctaatgcatgaacagcaggaaacctgggcacag
gatctaagtaaagtaagagagcggatgacaaaatttatagatgacactatgagagaaaca
gctgaaccattcctgtttgttgatgagttccttacttacctgttttcaaaagaaaacagc
atttgggatgataaatatgactctgttgacatgcaagacatgaataaccccttgtctcat
tactggatttcttcatctcataacacgtacctcaccggggaccaacttcgaagtgaatct
tccactgaatcgtacattcgatgtcttcgaatgggttgccggtgtatagagttggattgc
tgggatggacctgatgggaagccaatcatctatcatggctggacgcggacgacgaaaatc
aagtttgacgatgtggtgcaggccatcagagaccatgcttttgtctcctcacagttccca
gtgatcctctccattgaagaacactgctgtgtagaacagcaacgtcatatggccagggta
tttaaggaagtgtttggagacctcctccttacgaggcccactgaagccagtgctgaccag
cttccatcccctgcccagctgaaagaaaagatcataattaagcacaagaagctgggtccc
agaggagatgtggacatcaacattgaagacaagaaagaagaaaaaaagcagcaaggagaa
ctgtacatgtgggacaccattgatcagaaatggtatcgtcactattgtgccatagctgat
gagaagctgtctttcagtgatgatatagaacagaatatggaggaggattcagtaaaggat
gtagcacagactgacttgcattttggtgagaagtggtttcataaaagaatggagaagaga
acaagtgctgagaaactattgcaagaatactgtgctgaaactgggggcaaggatggaacc
ttcttagtccgtgaaagcgagactttccccaatgattatacactgtccttctggagatca
ggcagagtccagcactgtcgaatacggtcgactcctgagggagggaccatgaaatattat
ttgactgacaacctcatgttcaacagcatctatgacttgattcaacactaccgagaagcc
cacctgagatgtgctgaatttgaacttcgtttgacagacccagtgcccaaccccaatcct
catgaatcaaaagcttggtactatgatagcctgagcagaggagaagccgaagacatgttg
atgagaattccccgagatggagccttcctgattaggaaaagagaagggggcgatgcatac
gccattactttcagagccaagggaaaagtgaaacattgtcggattaacaaagatgggcac
cattttgtgctggggacctctgcttactttgaaagtttggtggaattggtcagctactat
gaaaagcatgcactctacaggaagatgaggctgcgctaccccgtgactcctgagctgcta
gaacgttacaacactgaaagggacataaattcgctctatgatgtaaggatgtatgtggat
cccagtgaaattaacccctcaacgcctcagagaaccgtgaaggctctatatgactacaaa
gccaagcgtagggatgagctcagcttttgtcggggagccctcatccacaacgtctccaag
gagcctggtggctggtggaagggtgattatggaggaaggattcagcaatattttccatct
aattatgtggaggacatatcaacagttgattttgaagagctggaaaaacagattattgaa
gataaccctttaggatccctatgcagaggaatcttggacctcaacacttacaacgttgtg
aaagtaccacatggaaaaaatcagaaatcatttgtgttcatcctggaacccaagaatccc
aatgatcctcctgtagagtttgcaacagacaaagtggaagaactctttgagtggtaccag
agcatcagagaaatcacttggaagaatgcaacagtggagaccaacatgaagtattgggag
aagaaccaatcaattgccatagagctatctgacttagttgtctactgtaaaccaaccagc
aaaaccaaggataatctagaaaatcctgatttcagagaaattcgctctttcgtggagacc
aaggctgacagcattgttaggcagaagccgattgatcttttgaaatacaatcaaaaggga
ctgactcgggtctacccgaaaggccaaagggtggactcatcaaattatgatccttttcga
ctttggctttgtggcgctcagatggttgctctgaatttccagacagcagataaatatatg
cagctaaaccatgctttatttgcacttaatggccggactggttatgtcctgcagcctgaa
agcatgaggaatgaaaactatgatccaacacccctggaatcacaaaggaagatcttgatg
accctgactgtgaaggtcttgggggcccgccatcttcctaagcttggccgaagcattgcc
tgtccatttgtagaggtggaaatttgtggcaccgagtatgataataacaaattcaagacg
acagtagtgaatgataatggtctgagtccagtctgggcgtctactcaggaaaaagtgaca
tttgaaatttatgacccgaatctcgcatttctacgttttgttgtttatgaggaggatatg
ttcagcgatcccaactttctggcacatgccacttatcccattaaaggaatcaaatcaggg
tttagatccgttcctcttaaaaatggttacagtgaagatattgaactggcctcccttttg
gttttctgtgagatgcgccctgtcttggaatgtgaagaagagctctattcttcctgtcgc
caacttcgaaggcgacaagaggagctgaataaccaactcttcctgtatgacactcatcag
aacatacgcaatgctaacagagatgccctagtgaatgaattcaatgtcaatgaaaatcag
ttgcagctgtatcaggaaaaatgcaacaggagattaagggagaagagagttagtaacagc
aaattctactcctag
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