KEGG   Gracilinanus agilis (agile gracile opossum): 123238271
Entry
123238271         CDS       T07702                                 
Symbol
MAPK8
Name
(RefSeq) mitogen-activated protein kinase 8
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas01522  Endocrine resistance
gas04010  MAPK signaling pathway
gas04012  ErbB signaling pathway
gas04014  Ras signaling pathway
gas04024  cAMP signaling pathway
gas04068  FoxO signaling pathway
gas04071  Sphingolipid signaling pathway
gas04137  Mitophagy - animal
gas04140  Autophagy - animal
gas04141  Protein processing in endoplasmic reticulum
gas04210  Apoptosis
gas04215  Apoptosis - multiple species
gas04217  Necroptosis
gas04310  Wnt signaling pathway
gas04380  Osteoclast differentiation
gas04510  Focal adhesion
gas04517  IgSF CAM signaling
gas04530  Tight junction
gas04620  Toll-like receptor signaling pathway
gas04621  NOD-like receptor signaling pathway
gas04622  RIG-I-like receptor signaling pathway
gas04625  C-type lectin receptor signaling pathway
gas04657  IL-17 signaling pathway
gas04658  Th1 and Th2 cell differentiation
gas04659  Th17 cell differentiation
gas04660  T cell receptor signaling pathway
gas04664  Fc epsilon RI signaling pathway
gas04668  TNF signaling pathway
gas04722  Neurotrophin signaling pathway
gas04723  Retrograde endocannabinoid signaling
gas04728  Dopaminergic synapse
gas04750  Inflammatory mediator regulation of TRP channels
gas04910  Insulin signaling pathway
gas04912  GnRH signaling pathway
gas04914  Progesterone-mediated oocyte maturation
gas04917  Prolactin signaling pathway
gas04920  Adipocytokine signaling pathway
gas04926  Relaxin signaling pathway
gas04930  Type II diabetes mellitus
gas04931  Insulin resistance
gas04932  Non-alcoholic fatty liver disease
gas04933  AGE-RAGE signaling pathway in diabetic complications
gas04935  Growth hormone synthesis, secretion and action
gas04936  Alcoholic liver disease
gas05010  Alzheimer disease
gas05012  Parkinson disease
gas05016  Huntington disease
gas05017  Spinocerebellar ataxia
gas05020  Prion disease
gas05022  Pathways of neurodegeneration - multiple diseases
gas05132  Salmonella infection
gas05133  Pertussis
gas05135  Yersinia infection
gas05142  Chagas disease
gas05145  Toxoplasmosis
gas05152  Tuberculosis
gas05161  Hepatitis B
gas05162  Measles
gas05166  Human T-cell leukemia virus 1 infection
gas05167  Kaposi sarcoma-associated herpesvirus infection
gas05169  Epstein-Barr virus infection
gas05170  Human immunodeficiency virus 1 infection
gas05171  Coronavirus disease - COVID-19
gas05200  Pathways in cancer
gas05208  Chemical carcinogenesis - reactive oxygen species
gas05210  Colorectal cancer
gas05212  Pancreatic cancer
gas05231  Choline metabolism in cancer
gas05415  Diabetic cardiomyopathy
gas05417  Lipid and atherosclerosis
gas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gas00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    123238271 (MAPK8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123238271 (MAPK8)
   04012 ErbB signaling pathway
    123238271 (MAPK8)
   04014 Ras signaling pathway
    123238271 (MAPK8)
   04310 Wnt signaling pathway
    123238271 (MAPK8)
   04668 TNF signaling pathway
    123238271 (MAPK8)
   04068 FoxO signaling pathway
    123238271 (MAPK8)
   04071 Sphingolipid signaling pathway
    123238271 (MAPK8)
   04024 cAMP signaling pathway
    123238271 (MAPK8)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    123238271 (MAPK8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    123238271 (MAPK8)
   04137 Mitophagy - animal
    123238271 (MAPK8)
  09143 Cell growth and death
   04210 Apoptosis
    123238271 (MAPK8)
   04215 Apoptosis - multiple species
    123238271 (MAPK8)
   04217 Necroptosis
    123238271 (MAPK8)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123238271 (MAPK8)
   04530 Tight junction
    123238271 (MAPK8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123238271 (MAPK8)
   04621 NOD-like receptor signaling pathway
    123238271 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    123238271 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    123238271 (MAPK8)
   04660 T cell receptor signaling pathway
    123238271 (MAPK8)
   04658 Th1 and Th2 cell differentiation
    123238271 (MAPK8)
   04659 Th17 cell differentiation
    123238271 (MAPK8)
   04657 IL-17 signaling pathway
    123238271 (MAPK8)
   04664 Fc epsilon RI signaling pathway
    123238271 (MAPK8)
  09152 Endocrine system
   04910 Insulin signaling pathway
    123238271 (MAPK8)
   04920 Adipocytokine signaling pathway
    123238271 (MAPK8)
   04912 GnRH signaling pathway
    123238271 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    123238271 (MAPK8)
   04917 Prolactin signaling pathway
    123238271 (MAPK8)
   04926 Relaxin signaling pathway
    123238271 (MAPK8)
   04935 Growth hormone synthesis, secretion and action
    123238271 (MAPK8)
  09156 Nervous system
   04728 Dopaminergic synapse
    123238271 (MAPK8)
   04723 Retrograde endocannabinoid signaling
    123238271 (MAPK8)
   04722 Neurotrophin signaling pathway
    123238271 (MAPK8)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    123238271 (MAPK8)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    123238271 (MAPK8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123238271 (MAPK8)
   05208 Chemical carcinogenesis - reactive oxygen species
    123238271 (MAPK8)
   05231 Choline metabolism in cancer
    123238271 (MAPK8)
  09162 Cancer: specific types
   05210 Colorectal cancer
    123238271 (MAPK8)
   05212 Pancreatic cancer
    123238271 (MAPK8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123238271 (MAPK8)
   05170 Human immunodeficiency virus 1 infection
    123238271 (MAPK8)
   05161 Hepatitis B
    123238271 (MAPK8)
   05171 Coronavirus disease - COVID-19
    123238271 (MAPK8)
   05162 Measles
    123238271 (MAPK8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123238271 (MAPK8)
   05169 Epstein-Barr virus infection
    123238271 (MAPK8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123238271 (MAPK8)
   05135 Yersinia infection
    123238271 (MAPK8)
   05133 Pertussis
    123238271 (MAPK8)
   05152 Tuberculosis
    123238271 (MAPK8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    123238271 (MAPK8)
   05142 Chagas disease
    123238271 (MAPK8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    123238271 (MAPK8)
   05012 Parkinson disease
    123238271 (MAPK8)
   05016 Huntington disease
    123238271 (MAPK8)
   05017 Spinocerebellar ataxia
    123238271 (MAPK8)
   05020 Prion disease
    123238271 (MAPK8)
   05022 Pathways of neurodegeneration - multiple diseases
    123238271 (MAPK8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123238271 (MAPK8)
   05418 Fluid shear stress and atherosclerosis
    123238271 (MAPK8)
   05415 Diabetic cardiomyopathy
    123238271 (MAPK8)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    123238271 (MAPK8)
   04936 Alcoholic liver disease
    123238271 (MAPK8)
   04932 Non-alcoholic fatty liver disease
    123238271 (MAPK8)
   04931 Insulin resistance
    123238271 (MAPK8)
   04933 AGE-RAGE signaling pathway in diabetic complications
    123238271 (MAPK8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    123238271 (MAPK8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gas01001]
    123238271 (MAPK8)
Enzymes [BR:gas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     123238271 (MAPK8)
Protein kinases [BR:gas01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   123238271 (MAPK8)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like FTA2 APH
Other DBs
NCBI-GeneID: 123238271
NCBI-ProteinID: XP_044521715
LinkDB
Position
2:complement(653805781..653926143)
AA seq 427 aa
MSRSKRDSNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPAPLGAAVISGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLETSA
GPLGCCR
NT seq 1284 nt   +upstreamnt  +downstreamnt
atgagtagaagcaagcgtgacagtaatttctatagtgtagagattggagattctacgttc
actgtactgaaacggtatcagaatttaaaaccaataggctcaggggcccagggaatagtc
tgtgcagcttatgatgccattcttgaaagaaatgttgcaatcaagaagctaagtcgacca
tttcagaatcagactcatgccaagcgggcttatagagagcttgttcttatgaaatgtgtt
aatcacaaaaatataattggcctcttgaatgtgttcacaccacagaagtctctagaagaa
tttcaggatgtttacatagtcatggagcttatggatgcaaatctttgccaagtcattcaa
atggagctagaccatgaacgaatgtcctaccttctctatcaaatgctgtgtggaatcaag
caccttcactctgctggaattatacatcgagacttaaagcccagtaatatagtagtaaaa
tcagactgcactttgaagattcttgactttggactggccagaactgcaggaactagtttt
atgatgacaccttatgtagtgactcgttactacagagcacccgaggtcatcctagggatg
ggctacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttgttcccaggtacagatcatattgatcagtggaataaagttattgaacaa
cttggaacaccatgccctgagttcatgaagaaattgcaaccaacagtaaggacttatgtg
gagaatagacctaaatatgctggatatagctttgagaagctcttcccagatgtacttttc
ccagctgactcagagcacaacaaacttaaagctagtcaggcaagggatttattgtcaaaa
atgctggtgatagatgcatctaaaagaatctctgtggatgaggctctccagcacccatat
atcaacgtctggtatgatccttcagaagcagaggcgcctccaccaaagatacctgacaag
cagttagatgaaagggagcacacaatagaagagtggaaagaattgatatacaaggaggtt
atggacttggaggagagaactaagaatggagttatacggggtcagccagctcctttaggt
gcagcagtgattagtggctctcagcatccatcttcatcatcgtctgtcaatgatgtgtct
tcaatgtcaacagatccaacattggcctctgatacagacagcagtctagaaacatcagct
ggacctctgggctgctgtagatga

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