KEGG   Gracilinanus agilis (agile gracile opossum): 123247702
Entry
123247702         CDS       T07702                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
gas  Gracilinanus agilis (agile gracile opossum)
Pathway
gas04010  MAPK signaling pathway
gas04012  ErbB signaling pathway
gas04620  Toll-like receptor signaling pathway
gas04664  Fc epsilon RI signaling pathway
gas04668  TNF signaling pathway
gas04912  GnRH signaling pathway
gas04926  Relaxin signaling pathway
gas04935  Growth hormone synthesis, secretion and action
gas04936  Alcoholic liver disease
gas05132  Salmonella infection
gas05135  Yersinia infection
gas05142  Chagas disease
gas05161  Hepatitis B
gas05166  Human T-cell leukemia virus 1 infection
gas05167  Kaposi sarcoma-associated herpesvirus infection
gas05169  Epstein-Barr virus infection
gas05208  Chemical carcinogenesis - reactive oxygen species
gas05417  Lipid and atherosclerosis
gas05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:gas00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    123247702 (MAP2K4)
   04012 ErbB signaling pathway
    123247702 (MAP2K4)
   04668 TNF signaling pathway
    123247702 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    123247702 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    123247702 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    123247702 (MAP2K4)
   04926 Relaxin signaling pathway
    123247702 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    123247702 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    123247702 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    123247702 (MAP2K4)
   05161 Hepatitis B
    123247702 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    123247702 (MAP2K4)
   05169 Epstein-Barr virus infection
    123247702 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    123247702 (MAP2K4)
   05135 Yersinia infection
    123247702 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    123247702 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    123247702 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    123247702 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    123247702 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:gas01001]
    123247702 (MAP2K4)
Enzymes [BR:gas01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     123247702 (MAP2K4)
Protein kinases [BR:gas01001]
 Serine/threonine kinases: STE group
  STE7 family
   123247702 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 123247702
NCBI-ProteinID: XP_044532618
LinkDB
Position
4:240689989..240869669
AA seq 391 aa
MAAPSPSGGSGSGSPGAVGSPGPGHTAVSSMQGKRKALKLNFANPPFKSTARFTLNPSGV
QNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIM
AVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKF
YKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDF
GISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLYELATGRFPYP
KWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFIL
MYEERTVEVACYVCKILDQMPATPTSPMYVD
NT seq 1176 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggtagcggtagcggctctcccggcgccgtagggtcc
cccgggccaggccacacggccgtcagcagcatgcagggtaaacgtaaagcactgaagctg
aattttgcaaatccacctttcaaatctacagcacggtttaccctgaatccttcaggagtc
caaaacccacacatagagagactgagaacacacagcattgaatcatcaggaaaactgaag
atctcccctgaacagcactgggatttcactgcagaggacttgaaagaccttggagaaatt
ggacgaggagcttatggttctgtcaacaaaatggtccacaaaccaagtgggcaaataatg
gcagttaaaagaattcggtctacagtggatgaaaaagaacaaaaacagctacttatggac
ttggatgtggtgatgcggagtagtgattgcccttatattgttcaattttatggagcactc
ttcagagagggtgactgttggatctgtatggaactcatgtctacctcgtttgacaagttt
tacaaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatc
actttagcaactgtgaaagcactaaaccacttaaaagaaaacttgaaaattattcacaga
gacattaaaccttctaatattcttctggatagaagtggaaatattaaactttgcgatttt
ggtattagtggacaacttgtggactctattgccaaaacaagagatgctgggtgcaggcca
tacatggcacctgaaaggatagatccaagtgcatcgaggcaaggatacgatgtccgttcc
gatgtatggagtctggggatcacactgtatgagctggctacgggccgattcccttaccca
aaatggaacagcgtttttgatcagctgacacaagtagtaaaaggagaccccccacagctg
agtaattccgaggaaagggaattttccccaagcttcattaactttgtcaacttgtgcctt
acaaaggatgaatccaaaaggccaaagtataaagaacttctgaaacatccctttattttg
atgtatgaagaacgcacagtggaggttgcatgctacgtttgtaaaatcctggatcaaatg
ccagcaactcccacctctcccatgtatgttgattga

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