KEGG T02442: 101139860

Gorilla gorilla gorilla (western lowland gorilla): 101139860

Entry

101139860         CDS       T02442

Symbol

CAPN1

Name

(RefSeq) calpain-1 catalytic subunit

K01367

calpain-1 [EC:3.4.22.52]

Organism

ggo Gorilla gorilla gorilla (western lowland gorilla)

Pathway

ggo04141

Protein processing in endoplasmic reticulum

ggo04210

Apoptosis

ggo04217

Necroptosis

ggo04218

Cellular senescence

ggo04382

Cornified envelope formation

ggo05010

Alzheimer disease

ggo05022

Pathways of neurodegeneration - multiple diseases

Brite

KEGG Orthology (KO) [BR:ggo00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101139860 (CAPN1)
09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    101139860 (CAPN1)
   04217 Necroptosis
    101139860 (CAPN1)
   04218 Cellular senescence
    101139860 (CAPN1)
09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    101139860 (CAPN1)
09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101139860 (CAPN1)
   05022 Pathways of neurodegeneration - multiple diseases
    101139860 (CAPN1)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ggo01002]
    101139860 (CAPN1)
Enzymes [BR:ggo01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.52  calpain-1
     101139860 (CAPN1)
Peptidases and inhibitors [BR:ggo01002]
Cysteine peptidases
  Family C2: calpain family
   101139860 (CAPN1)

SSDB

Motif

Pfam:

Peptidase_C2 Calpain_III EF-hand_6 EF-hand_1 EF-hand_8 EF-hand_7 CAPN13-like_C_EFh

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

9:join(73093734..73094000,73094160..73094229,73094504..73094622,73096962..73097095,73097215..73097383,73098263..73098346,73099009..73099094,73099468..73099542,73099640..73099800,73115742..73115917,73116752..73116763,73117502..73117713,73117819..73117858,73119081..73119146,73119231..73119288,73120349..73120413,73120875..73120943,73121044..73121122,73121362..73121478,73121823..73121881,73122269..73122295)

AA seq 714 aa
MSEEIITPVYCTGVSAQVQKQRARELGLGRHENAIKYLGQDYEQLRVRCLQSGTLFRDEA
FPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAA
IASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHS
AEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILK
ALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQMVSLIRMRNPWGE
VEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS
RTIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFV
LALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINL
REVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTAELDDQIQANLPDEQVLSE
EEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRD
GNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELII
TRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA

NT seq 2145 nt +upstreamnt +downstreamnt
atgtcggaggagatcatcacgccggtgtactgcaccggggtgtcagcccaagtgcagaag
cagcgggccagggagctgggcctgggccgccatgagaatgccatcaagtacctgggccag
gattatgagcagctgcgggtgcgatgcctgcagagtgggaccctcttccgtgatgaggcc
ttccccccggtgccccagagcctgggttacaaggacctgggtcccaattcctccaagacc
tatggcatcaagtggaagcgtcccacggagctgctgtcaaacccccagttcatcgtggat
ggagctacccgcacagacatctgccagggagcactgggggactgctggctcttggcggcc
atcgcctccctcactctcaacgacacccttctgcaccgagtggttccgcacggccagagc
ttccagaatggctatgccggcatcttccatttccagctgtggcaatttggggagtgggtg
gacgtggtcgtggatgacctgctgcccatcaaggacgggaagctagtgttcgtgcactct
gccgaaggcaacgagttctggagcgccctgcttgagaaggcctatgccaaggtaaatggc
agctacgaggccctgtcagggggcagcacctcagagggctttgaggacttcacaggcggg
gtcaccgagtggtacgagttgcgcaaggctcccagtgacctctaccagatcatcctcaag
gcgctggagcggggctccctgctgggctgctccatagacatctccagcgttctagacatg
gaggccatcaccttcaagaagctggtgaagggccacgcctattctgtgaccggggccaag
caggtgaactaccgaggccagatggtgagcctgatccggatgcggaacccctggggcgag
gtggagtggacgggagcctggagcgacagctcctcagagtggaacaacgtggacccatat
gaacgggaccagctccgggtcaagatggaggatggggagttctggatgtcattccgagac
ttcatgcgggagttcacccgcctggagatctgcaacctcacacccgacgccctcaagagc
cggaccatccgcaaatggaacaccacactctacgaaggcacctggcggcgggggagcacc
gcggggggctgccggaactacccagccaccttctgggtgaaccctcagttcaagatccgg
ctggatgagacggatgacccagacgactacggggaccgcgagtcaggctgcagcttcgtg
ctcgcccttatgcagaagcaccgtcgccgcgagcgccgctttggccgcgacatggagact
attggcttcgcggtctacgaggtccctccggagctggtgggccagccggccgtacacttg
aagcgtgacttcttcctggccaatgcgtctcgggcgcgctcagagcagttcatcaacctg
cgagaggtcagcacccgcttccgcctgccacccggggagtatgtggtggtgccctccacc
tttgagcccaacaaggagggcgacttcgtgctgcgcttcttctcggagaagagtgctggg
accgcggagctggatgaccagatccaggccaatctccctgatgagcaagtgctctcagaa
gaggagattgacgagaacttcaaggccctcttcaggcagctggcaggggaggacatggag
atcagcgtgaaggagttgcggacaatcctcaataggatcatcagcaaacacaaagacctg
cggaccaagggcttcagcctagagtcgtgccgcagcatggtgaacctcatggatcgtgat
ggcaatgggaagctgggtctggtggagttcaacatcctgtggaaccgcatccggaattac
ctgtccatcttccggaagtttgacctggacaagtcgggcagcatgagtgcctacgagatg
cggatggccattgagtcggcaggcttcaagctcaacaagaagctgtacgagctcatcatc
acccgctactcggagcccgacctggcagtcgactttgacaatttcgtgtgctgcctggtg
cggctagagactatgttccgatttttcaaaactctggacacagatctggatggagtcgtg
acctttgacttgtttaagtggttgcagctgaccatgtttgcatga

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