KEGG   Globicephala melas (long-finned pilot whale): 115854215
Entry
115854215         CDS       T11080                                 
Symbol
CAD
Name
(RefSeq) multifunctional protein CAD
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
gmf  Globicephala melas (long-finned pilot whale)
Pathway
gmf00220  Arginine biosynthesis
gmf00240  Pyrimidine metabolism
gmf00250  Alanine, aspartate and glutamate metabolism
gmf01100  Metabolic pathways
gmf01240  Biosynthesis of cofactors
Module
gmf_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:gmf00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    115854215 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    115854215 (CAD)
   00220 Arginine biosynthesis
    115854215 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:gmf01002]
    115854215 (CAD)
Enzymes [BR:gmf01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     115854215 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     115854215 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     115854215 (CAD)
Peptidases and inhibitors [BR:gmf01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   115854215 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   115854215 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp Dala_Dala_lig_C MGS ATPgrasp_Ter Amidohydro_1 DHOase ATP-grasp_3 GARS_A Peptidase_C26
Other DBs
NCBI-GeneID: 115854215
NCBI-ProteinID: XP_030714003
LinkDB
Position
12:complement(69227554..69252347)
AA seq 2225 aa
MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPPDEVDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSATCTLHEWLQQRGIPGLQGVD
TRELTKKLREQGSLLGKLVQDGTEPSTLPFLDPNARALVPEVSIKVPRVFNSGGTPRILA
LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
TDSLPAGWLPLFTNANDHSNEGIVHESLPFFSVQFHPEHHAGPSDMELLFDIFLDTVKEA
TTRNPGGQTVRERLAERLCLRGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFASRMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASNKEELSALVAPAFAHTSQVLVDKSLKGWKEI
EYEVVRDTYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRM
KRIVAHTQLLEQHRGQSLPLPLLQQAKRLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGTTHDLSFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMV
CAMPNTRPPIIDAPALALAQKLAEAGARCDYALFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPSHLPIVAHAERQSVAAVLMVAQLTQRSVHICHVARKEE
ILLIKAAKARGLPVTCEVAPHHLFLSRDDLERLGPGKGEVRPELGSRQDVEALWENMAVI
DCFASDHAPHAVDEKCGPQPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
HLPPQEDTYVEVDLEHEWTVPNHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGAVPQLTPSAPAASELNTTPERPRRGIPALPDGRFHLPPRIHRASD
PGLPAEEPKEKTSRKAAEPELMGTLDGTCYPPPPIPRQASPQNLGTTGLLHPQTSPLLHS
LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLRMPPDVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSSQEYEA
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq 6678 nt   +upstreamnt  +downstreamnt
atggcggccctggtgttggaggacgggtcggtcctgcggggccagccctttggggccgct
gtgtcgactgccggggaagtggtgtttcaaaccggtatggtcggctaccccgaggccctc
actgacccttcctacaaagcacagatcttagtgctgacatatcctctgattggtaactac
ggcattcccccagatgaagtggatgagttcggactcagcaagtggtttgaatcctcgggg
atccacgtggcaggactggtggtaggagagtgctgccccacacccagccactggagtgcc
acctgtaccctgcatgagtggctgcaacagcgtggcatacccggcctacaaggagtggac
actcgggagctgactaagaagttgcgagagcaagggtctctgctgggaaagctggtccag
gatgggacggagccttcaaccctgccgttcttggaccccaatgcccgcgccctggtgccg
gaggtctccattaaggtcccacgggtattcaattcagggggcacccctcggatccttgct
ttggactgtggcctcaagtataatcagatccgatgcttgtgccagcgtggggcagaggtc
actgtggtaccctgggaccacgcattagacagtcaggagtatgagggtctctttctgagt
aatggccctggcgaccccgcctcctatcccagcgtggtatccacactgagccgtgtctta
tctgaaccgaacccccgacctgtctttgggatctgcctgggacaccagctgttggcctta
gccattggggccaagacttacaagatgagatatgggaaccgaggccataaccagccatgc
ttgctggtgggctctgggcgctgctttctaacatcccagaaccatgggtttgctgtggaa
acagactcactgccagcaggctggcttcctcttttcaccaacgccaacgatcactccaac
gaaggcattgtacatgagagcctgcccttcttcagtgtccagtttcacccagagcaccac
gctggcccttcagatatggaacttctttttgatatatttctggacactgtgaaagaagcc
accaccaggaaccctgggggccagacagttcgagagcggctggctgagcgcctctgtctc
cgtgggattcccaccccaggctctgggcttccaccaccacgaaaggttctgattctgggc
tcagggggcctctccattggccaagccggagagtttgactactcaggctctcaggcgatc
aaggccctgaaggaggagaacatccagacgttgctgatcaaccccaacattgccaccgtg
cagacctcccaggggctggctgacaaggtctatttcctcccaataacgcctcactacgta
acccaggtgatacgtaatgagcgcccagatggcgtgttactgacttttgggggccaaaca
gctctgaactgtggtgtggagctgaccaaggctggggtgctcgctcggtatggggtccgg
gtcctgggcacacccgtggagaccattgagctgactgaggatcggcgcgccttcgcctcc
aggatggccgagatcggagagcacgtggcccccagtgaggcagcaaactctcttgagcag
gcccaggcagctgccgagagactggggtaccccgtgctggtgcgtgcagcctttgccctg
gggggcctgggctctggctttgcctctaacaaagaggagctctctgctctcgtggcccca
gcttttgcccataccagccaagtgctggtagacaagtccctgaaaggatggaaggagatt
gagtatgaggtggtgagagacacctatggcaactgtgtcacggtgtgtaacatggagaac
ctagatccactgggcatccacactggggagtccatagtggtggctccaagccagacgctg
aatgacagggagtaccagctactgcggcagacggccatcaaggtgactcagcaccttgga
attgttggggagtgcaacgtgcagtatgccttgaatcctgagtctgagcagtattacatc
attgaagtgaatgccaggctctcgcgcagctccgccctggccagtaaggccacaggctat
ccactggcctacgtggcagccaagctggctttgggcatccctctacctgaactcaggaac
tcggtgacagggggaacagcagcctttgaacccagtctggattattgtgtggtgaagatt
cctcgctgggacctcagcaagttcctccgtgtcagcacaaagattgggagctgcatgaag
agtgtcggtgaggtcatgggcattgggcgttcttttgaggaagctttccagaaggctctg
cgcatggtggatgagaactgcgtgggctttgatcacacagtcaagcccgtcagtgacatg
gagctggagactccaacagacaagcgcatctttgtggtggcagctgccctgtgggctggc
tactcggtggatcgcctgtacgaacttactcgcatcgaccgctggtttttgcaccgaatg
aagcggatcgtagcacacacccagctgctggagcaacaccgtggacagtctctgccccta
cccctgctgcagcaggccaagcgcctcggcttctcagacaagcagattgccctcgcagtt
ctcagcacagagctggctgttcgcaagctgcgtcaggaactggggatctgcccagcggtg
aagcagattgacacagttgcagctgaatggccagcccagacaaattacttgtacctgaca
tactggggcaccacccatgacctcagctttcgaacgcctcatgtcctggtcctgggctct
ggcgtctaccgtatcggctccagcgtcgagtttgactggtgtgctgtgggctgcatccag
cagctccgaaagatggggtataaaaccatcatggtgaactacaacccagaaacagtcagc
accgactatgacatgtgtgaccgactctacttcgatgagatctcttttgaggtggtgatg
gacatctatgagctagagaaccccgaaggcgtgatcctgtccatgggcgggcagctgccc
aacaacatggccatggctttgcatcggcagcagtgccgggtgctgggcacctcccctgaa
gccatcgactcggctgagaaccgttttaagttctcccggctcctggacaccattggtatc
agccagcctcagtggagggagctcagtgacctagagtctgcccgccagttctgccagacc
gtggggtacccctgtgtcgtgcgcccctcctatgtgctaagtggtgctgctatgaacgtg
gcttacaccgatggggacctggagcgcttcctgagcagtgcggcagctgtctccaaggag
caccccgtggtcatctccaagttcatccaggaggccaaggagattgatgtggacgctgtg
gcctgtgatggtgtggtggcagccatcgccatctccgagcacgtggagaacgcaggtgtg
cattcaggtgatgccacgctggtgaccccgccgcaggacatcactgccaaaaccctggag
cggatcaaagccatcgtgcacgccgtgggccaggagctgcaggtcacaggacccttcaat
ctgcagctcattgccaaggacgaccagctgaaagtcattgaatgcaacgtgcgtgtctcc
cgctccttccccttcgtctccaagaccctgggtgtggacctagtagccttggccacgcgg
gtcatcatgggggaagaagtggagcctgtggggctcatgactggctctggagtcgtgggg
gtaaaggtgccccagttctcgttctcccgcctggcgggtgctgatgtggtgctgggtgtg
gagatgaccagtaccggggaagtggctggcttcggggagagccgctgtgaggcctacctc
aaggccatgctaagcactggctttaagatccccaagaagaacatcttgctgaccattggc
agctataagaacaaaagtgagctgctcccaactgtgcgactgctggagagcctgggctac
agcctctacgccagcctgggcactgctgacttctatacagagcacggtgtcaaggtaacg
gctgtggactggcactttgaagaagcagtggatggagagtgtccaccacagcgaagtatc
ctggagcagctcgctgagaagaacttcgagctagtgattaacctgtccatgcgcggggcc
gggggccggcgtctctcttcctttgtcaccaagggctaccgcacccggcgcctggccgct
gacttctccgtgcccctcatcatcgatatcaagtgcaccaaactgtttgtggaggcccta
ggacagattgggccagcccctcctttgaaggtgcatgttgactgcatgacctcccagaag
ctcgtgcggctacctggattgattgatgtccacgtgcacctgcgggaaccaggggggaca
cacaaggaggacttcgcttcaggcacagcggctgccctggccgggggcatcaccatggtg
tgcgccatgcctaatacccggccccccatcatcgatgcccctgctctggccctggcacag
aagctggcagaggccggcgcccgctgtgactatgccttattcctcggagcttcgtcggaa
aacgcagggaccctgggtgctgtggctgggtctgctgcagggctgaagctctacctcaac
gagaccttctccgagctgcggctggacagtgtggcccagtggatggagcacttcgagacg
tggccgtcccacctccccattgtggcccacgcagagcgtcagagtgtggccgccgtcctc
atggtggcccagctgacccagcgctcggtacacatctgtcacgtggcgcggaaggaagag
atcctgctgattaaagccgcaaaggcacgggggctgccggtgacctgtgaggtggcgccc
caccatctgttcctgagccgcgatgacctggagcgtctggggcccgggaagggggaggtt
cggcctgagcttggctcccggcaggatgtggaagccctatgggagaacatggccgtcatc
gactgctttgcctccgaccatgccccccacgccgtggacgagaagtgtgggccccagcca
ccccccggcttcccggggttggagaccatgctgcccctactgctgacggcagtgagcgag
ggccggctcagcctggatgacctgctgcagcgactgcaccacaacccccggcgcatcttc
cacctgccgccccaggaggacacctatgtggaggtggatctggagcatgaatggacggtc
cccaaccacatgcccttctccaaggcccactggacaccctttgaagggcagaaggtgaag
ggcaccgtccgccgtgtggtcctgcgaggagaggttgcctatattgacgggcaggtgctg
gtgccgccgggctacggacaggatgtacgcaagtggccacagggggctgttccccagctc
acgccctcggcccccgccgccagtgagctaaacacgaccccagagaggccccgccggggc
atcccagcgcttcccgatggccgcttccacctgccgccccgaatccaccgagcctctgac
ccaggtttgccagctgaggagccaaaggagaagacctcccggaaggcagctgagccagag
ctgatgggaacccttgacggcacctgctaccctccaccaccaatacctagacaggcgtcg
ccccagaacctggggaccactggcctgctgcacccccagacctcacccctgctgcactca
ttggtgggccaacatatcctgtctgtccagcagttcaccaaggatcagatgtctcacctg
ttcaacgtggcacacacgctgcgcatgatggtgcagaaggagcggagcctcgacatcctc
aaggggaaggtgatggcctccatgttctacgaggtgagcacgcggaccagcagctccttt
gcagcggccatggcccggctggggggcgccgtgctcagcttctcagaagccacgtcctcc
gtccagaagggtgaatccctggctgactcggtgcagaccatgagctgctacgccgacgtc
gtggtgctgcggcacccccagcccggagcggtggagctggcagccaagcactgccggagg
ccagtgatcaatgccggggatggggtcggagagcatcccacccaggccttgctggacatc
ttcaccatccgggaggagcttgggacggtcaacggcatgacgatcacaatggttggggac
ctgaagcacggacgcacggtgcattcactggcctgcctgctcacccagtatcgcgtcagc
ctgcgctacgtggcgcctcccagcctgcgcatgccccccgacgtgcgggctttcgtggcg
tcccgcggcaccaagcaggaggaatttgagagcatcgaggaggcgctgcccgacaccgac
gtgctctacatgactcgcatccagaaggagcgctttgggtctagccaggagtatgaagct
tgcttcggccagttcatcctcactccccacatcatgacccgggccaagaagaagatggtg
gtgatgcaccccatgccccgagtcaatgagataagtgtggaggtggactcggacccccga
gcagcctacttccggcaggcggagaatggcatgtacatccgcatggctctgttagccact
gtgctcggccgcttctag

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