KEGG   Geotrypetes seraphini (Gaboon caecilian): 117357148
Entry
117357148         CDS       T09159                                 
Symbol
CAD
Name
(RefSeq) CAD protein isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
gsh  Geotrypetes seraphini (Gaboon caecilian)
Pathway
gsh00220  Arginine biosynthesis
gsh00240  Pyrimidine metabolism
gsh00250  Alanine, aspartate and glutamate metabolism
gsh01100  Metabolic pathways
gsh01240  Biosynthesis of cofactors
Module
gsh_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:gsh00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    117357148 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    117357148 (CAD)
   00220 Arginine biosynthesis
    117357148 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:gsh01002]
    117357148 (CAD)
Enzymes [BR:gsh01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     117357148 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     117357148 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     117357148 (CAD)
Peptidases and inhibitors [BR:gsh01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   117357148 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   117357148 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 MGS ATP-grasp Dala_Dala_lig_C DHOase ATPgrasp_Ter Amidohydro_1 ATP-grasp_3 Peptidase_C26 GARS_A
Other DBs
NCBI-GeneID: 117357148
NCBI-ProteinID: XP_033793389
UniProt: A0A6P8QAK2
LinkDB
Position
3:141189572..141597787
AA seq 2243 aa
MASLLLEDGSVYRGRLFGAVASVSGEVVFQTGMVGYPEALTDPSYKSQILVLTYPLIGNY
GIPQDEQDEYGLSRWFESSQIHVSALIVGEKSQIPSHWCSILSLDQWLKEQNVPGLEGVD
TRALTKKIREKGTMLGKLIVDGTDGGTVLYDDPSKRNLVQEVSLKEPQVFNPSGTLRIIA
LDCGLKYNQIRCLCQRGAAVKVVPWNHPLDAEEFDGLFISNGPGDPVFCQEAIENIRQMI
TKEDPIPVFGICLGHQILSLVIGAKTYKMKYGNRGHNQPCIHTDTKRCFITSQNHGYAVS
PETLPKGWSVLFTNANDHSNEGIIHEEKPFFSVQFHPEHRAGPMDLVGLFDVFIEVVKDR
KNRIHGGKTVKERLTEQLTYRDAPKEDLLASRPFKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEESIQTVLINPNIATVQTSKGLADKVYFLPITADYVTQVIKNERPDGILLTFGGQT
ALNCGVELTKQGVLERYSVRVLGTPVASIEMTEDRKVFVEKMEEIGEHVAPSEAAFSVEQ
AQAAAERLGYPVLVRSAYALGGLGSGFANSKEELTGLVCQAFAHTTQVLVDKSLKGWKEI
EYEVVRDAYNNCITVCNMENVDPLGIHTGESIVVAPSQTLNDREYNILRNTAIKVVQHLD
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPVLRN
SVTDSTTANFEPSLDYCVVKIPRWDLSKFLRVSTKIGSSMKSVGEVMSVGRNFEEAFQKA
LRMVDENCVGFDHTVKPVSDMELETPTDKRIFVLAAALKAGYTIDHLYELTKIDRWFLHK
MKNITDHVMILETYREDGTKMPSEVLLKAKQLGFSDKQIAQAVQSTELAVRKMRQDWKIL
PVVKQIDTVAAEWPAQTNYLYLTYNGMEHDLLFRDPHVMVIGSGVYRIGSSVEFDWCAVG
CIQELRKMGFKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGMILSMGG
QLPNNIAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWKELSDMESAMQF
CSKVGYPCLVRPSYVLSGAAMNVAYSDSDLEKFLNSAIAVSKEYPVVISKFIQEAKEIDV
DAVACDGVVVAIAISEHVENAGVHSGDATLVTPPQDITPKTLERIKAIVHAIGQELQVTG
PFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDMVALATQVIIGEEVEPVGLMTGTG
IVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGESRCEAYLKAMLSTGFKIPKKNILL
TIGSYKNKNELLPTVRTLERLGYSLYASMGTADFYTEHGIKVKAVDWPFEESDNDCPLKE
KQRSIMDYLAENHFDMVINLSMRNSGGRRLSSFVTKGYRTRRLAVDYSVPLIIDIKCTKL
FVEALRQIGMAPPVKTHVDCMTSQKLIRLPGLIDIHVHLREPGGTHKEDFASGTAAALAG
GITMVCAMPNTIPAITDPSSFALAQKLAEAGARCDFALFLGAASDNVGTLTPIASTAAGL
KMYLNDTFSNLKMDNVSLWMEHFEKWPKHLPIVAHAEKQTVAAILMVAQLYQRPVHICHV
ARKEEILIIKAAKQKGIQVTCEVAPHHLFLCLDDLERIGETRGQVRPMLGTREDMNALWE
NLETIDCFATDHAPHSVEEKNGKNAPPGYPGLETMLPLLLTAVSEGRLTIDDIIKRLYEN
PQKIFSLPIQENTYIEVDLEQEWIIPSHMQFTKSKWTPFEGMKVKGAMRRVILRGEVAYI
DGQVLVPPGYGQDVRKWPTGIASVPHPAPVNEILKTPEHHRHAAQNEIIRGRAPSPRRTG
PTGDGRFHLPPRIHRASDPGLPAAEELKEKSTKKPAEPDLAVIQDGYLYPPPLPRMPSPQ
NVPMQILPHPQTSPLLHPLIGQHVLSVKQFSKDQMSHLFNVAHNLRMMVQKERALDILKG
KVMASMFYEVSTRTNSSFSAAMYRLGGSVISFSESTSSTQKGESVADSVQTMSCYADVVV
LRHPNPGAVEFAAKHCRKPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLK
HGRTVHSLARLLTQYRVNLRYVTPHNLCMPSDIIHFVASKGIKQEEFDSIEEALPDTDVL
YMTRIQKERFDSVQEYSSCFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAA
YFRQAENGMFIRMALLATVLGKY
NT seq 6732 nt   +upstreamnt  +downstreamnt
atggcctcgttgctgctggaggacgggtcggtttacagaggccgcctctttggcgccgtc
gcctcagtgtccggggaagtggtgttccagacaggcatggtgggttatcctgaggcactg
acagatccttcatataaatctcaaattctggtcctgacctaccctcttattgggaattat
gggataccgcaggatgaacaagacgagtatggtctgagccggtggtttgaatccagccaa
atccacgtgtctgccctgattgtgggagagaagtctcagatccctagccactggtgctcc
atcttgtcattggaccagtggctgaaggagcagaatgttcctggactagaaggggtggat
accagagccctgactaaaaagatacgagagaaaggaacaatgttggggaaactgattgtg
gatggcaccgatggaggcactgtcctatatgatgaccccagcaaaaggaatctggtgcag
gaagtctcactaaaggagccgcaggttttcaatcccagtggcacattgaggattatagcc
ctggactgtggtctgaagtataaccaaatccgctgcctatgtcagagaggggctgcagtg
aaggtagtgccttggaatcatcccttagatgccgaagagtttgatggtctgtttatcagc
aatggtcctggggatcctgtcttctgtcaggaagccatagagaacatccggcaaatgatc
acaaaggaggacccgatacctgtgttcgggatctgcctgggccaccagatcctctcattg
gttattggggccaaaacctacaaaatgaaatatggcaatcgtggccacaaccagccatgt
atccatactgatactaagcgttgcttcatcacatcccagaatcatggttatgctgtcagt
cccgagacactacctaagggctggtccgtccttttcaccaatgctaatgatcactccaac
gagggtattattcatgaggagaagcctttcttcagtgttcagttccatcctgagcacaga
gctggcccaatggatcttgtgggcctcttcgatgtcttcatagaggtggtaaaggacagg
aagaataggatccatggtgggaaaacagttaaggaacggttgacagaacagctaacatac
agagatgcacccaaggaggatttgttagcatctcgtcctttcaaggtcctgatcctgggc
tcaggaggtctctccataggacaagctggagaatttgactactctggctctcaggctatt
aaagctctgaaggaagagagtatccagactgtgctgatcaaccccaacatagccacagtg
caaacctcaaaaggcctagctgacaaggtgtacttcctgcccatcacagcagactatgtg
acacaggtaataaagaatgagcgtccagatgggatcctgctaacatttggaggtcagaca
gcattgaactgtggggtggagctgactaagcaaggtgtcctggagcgatacagtgtgcgg
gttctaggtactcccgtggcttccattgagatgacagaagatcgtaaggtgtttgtggag
aagatggaagagattggtgaacatgtggcccctagtgaggcagccttctctgtggagcag
gcacaggctgcagctgagagactggggtaccctgtcttggtgcgatctgcctatgcactt
ggaggtctgggctctggatttgccaacagtaaagaagagctgacaggtttggtgtgccag
gcatttgcccacacaactcaggtgcttgtggacaaatccttgaagggctggaaggaaatt
gagtatgaggttgtccgagatgcctacaacaactgcattacggtttgcaacatggagaat
gtggatcccctggggattcatacaggagaatccattgttgtggcacctagtcagacactt
aatgaccgtgagtacaacatccttcgaaatactgcaatcaaagtggtgcagcacctggac
atcgtaggagagtgcaacgtccagtatgctctaaacccagaatctgaacagtattacatt
attgaggtgaacgctcggctctccagaagctcggctctagcgagtaaagccactggctac
cctctggcatatgtggctgcaaagctggcacttgggatccctttgcctgttctcagaaac
tctgttactgactccaccacagcaaactttgagcccagcttggattactgcgtagtgaag
atcccccggtgggacctaagtaaattcctgcgggttagcacaaagattggaagctccatg
aagagtgttggtgaagtgatgtctgtggggcggaactttgaggaggctttccagaaggca
ctgaggatggtggatgagaattgcgtggggtttgaccacacggtgaagccagtatctgac
atggagctggagactcccactgataaaaggatctttgtgctggctgcagcccttaaggcc
ggatacaccattgatcacttgtatgagctcaccaagatagaccgctggtttctacataag
atgaaaaacatcacagaccatgttatgatactggaaacataccgtgaagatggaaccaaa
atgccctcggaggtgctgctgaaggctaaacaactgggtttttcagataaacaaattgcc
caagcagtgcagagcacggaactggcagtgaggaagatgaggcaggactggaaaatctta
cctgtggtgaagcaaatagatacagtggctgcagagtggccagctcagaccaactacttg
tacctgacctacaatggaatggagcatgatctgctcttccgagaccctcatgtcatggtg
attggttctggtgtttaccgcattggtagcagtgtggagtttgactggtgtgctgtggga
tgcatccaggagctacgcaagatgggattcaagactattatggtgaattataacccagag
actgtgagcactgattatgacatgtgtgatcgcttatactttgatgaaatatcatttgag
gttgtgatggatatatatgagttagagaaccctgaaggtatgattttgtccatgggagga
caacttccaaacaatattgctatggccctccaccgccagcagtgccgtgtccttggcacc
tcgccagaagccatagattctgctgagaaccgctttaaattttcccgcctactggacaca
attggaatcagccagccccagtggaaggagctctctgatatggagtcagctatgcagttt
tgcagtaaggtggggtatccatgtctggttcgcccatcttatgtgctcagtggagcagca
atgaatgtggcatactcagacagtgatctggagaaattcctcaacagtgcaatagctgtg
tccaaagaataccctgtggtcatctccaagttcattcaggaagccaaggaaattgatgtg
gatgccgttgcttgtgatggagtggttgttgcaattgccatatctgaacatgtggagaat
gctggtgttcattcaggggatgctaccctggtcactcccccccaggatatcaccccaaag
actttggagagaatcaaagccatcgtccatgctatcgggcaagagttacaggttacaggg
cccttcaatctgcagttaattgcaaaggatgaccagctgaaggtgattgaatgcaacgtg
agggtttcacgttcttttccctttgtatccaagaccctgggcgtggacatggtggctctt
gctacacaggtcatcataggagaagaagtggagccagttggacttatgacgggaactgga
attgttggcgtgaaggttccccagttctcattctctcgactggcaggagcagatgtggta
ttgggagtagagatgaccagcacaggagaagtggcctgctttggagagtcccgctgtgaa
gcttaccttaaggctatgctgagcactggtttcaaaataccaaagaaaaacattctactg
accattgggagctacaagaacaagaacgaactgctccctacagtgcggactctcgagcgt
ctaggatacagtctgtatgccagcatgggaactgctgatttttacacagagcatgggatc
aaggtgaaggcagtagactggccctttgaagagagtgacaatgattgccccctgaaggaa
aaacaaaggagcataatggactacctggctgagaaccattttgacatggtgatcaatctc
tccatgcgcaactcaggaggtcgccgcctctcctccttcgttaccaaaggttaccgcact
cgtaggctggctgtggactactctgtgccactcatcatagatatcaagtgcaccaagctg
tttgttgaggccctgcggcaaataggcatggctcctccagtgaagacgcatgtggattgc
atgacatcccagaaactcattcggttaccaggtctcatcgatatccacgttcatttacga
gagcctggtggtacacacaaagaagactttgcctctggcacagctgctgctctggcaggg
ggcatcactatggtgtgcgctatgcccaacaccatccctgccatcactgaccccagttcc
tttgcactggcacagaagctagctgaagcaggagcccgctgtgactttgctctttttctt
ggtgctgcttcagacaatgttggtacattgaccccaattgccagcacagcagctggtctc
aaaatgtacctgaatgataccttctctaacctcaagatggataacgtgtcactatggatg
gagcattttgaaaagtggccaaagcatctgcccattgtagctcatgctgaaaagcagacg
gtcgctgcaatactgatggtggctcagttgtatcaacggcctgtccatatctgccatgtc
gctcggaaagaggagattctgatcattaaagctgccaaacagaagggaatccaggtgacc
tgcgaggtagctccacaccacctttttttgtgcctggatgatctggaacgaattggtgag
acccgtggccaggttcggcccatgctgggcacacgggaggacatgaatgctctctgggag
aatctagagaccattgattgctttgctactgatcatgcacctcattctgtggaagagaag
aatggtaagaatgcccctcctggctaccctggtctggaaaccatgctgcctttattgttg
actgctgtcagtgaagggcgcctgacaattgatgacatcatcaaacggctatacgagaac
ccgcagaagatcttctcactacctatacaggagaacacatacatagaggtggatctggaa
caggaatggataatccctagtcacatgcagttcactaaatccaaatggacaccatttgaa
ggcatgaaggtgaaaggagccatgagaagggtaatcttgcgaggagaagttgcctacatt
gatggtcaggtattggtgcccccaggttatggccaggatgtcagaaagtggccaactgga
atagcatctgtaccccaccctgctccagtgaatgaaatcctcaaaacaccagaacatcat
cgtcacgctgcacagaatgagattatccgcggccgagctccaagtccccgaagaactggg
cccactggggatgggcgctttcacttacctccacgaatccaccgtgcctctgatccaggc
cttccagcagctgaagagctaaaggaaaagtcaaccaagaaaccagcagagccagaccta
gcagttatccaggatggttacttgtaccctcctccattacccaggatgccctccccacag
aacgtgcctatgcagattctcccccatccacagacttctccactgttgcatcccctcatt
gggcagcatgtcctttcagttaaacagttttccaaagaccagatgtctcacctgtttaat
gtggctcataacctgcggatgatggtacagaaggagagagccctggacattctcaagggt
aaggtaatggcctccatgttttatgaagtcagcaccagaaccaacagctctttctctgca
gctatgtatcgccttggggggtcagtcatcagcttctccgagtctacctcatccacccag
aagggagaatctgtggcagattctgtgcagaccatgagttgctatgcggatgtggtagtt
ctacgacaccccaaccctggtgccgtggagtttgctgcaaagcattgtcggaaaccagtg
ataaatgccggtgatggagttggggaacatcccacccaggctctgttggacatctttact
atccgggaagagctgggaacagtcaatgggatgacgatcacgatggtgggagacttgaag
catggccgtactgtgcactcacttgcccgcttgttgactcaatatcgtgtgaatctgcgc
tacgtcacaccccacaacctgtgtatgccctcagatatcatacactttgtggcctccaag
gggattaaacaggaagagtttgatagcattgaggaggctcttcctgatacagatgttttg
tacatgactcgaattcagaaggaaaggtttgattctgtccaggagtacagttcttgtttt
gggcagtttattctgacaccgcacatcatgactagagcaaagaaaaagatggtagtgatg
caccccatgccacgtgtcaatgagatcagtgttgaagtggattctgatccaagagctgct
tattttcggcaggcagagaatggtatgtttatccgtatggctctgctggccacagtgctg
ggcaaatactag

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