Gavia stellata (red-throated loon): 104259035 Help Entry 104259035         CDS       T08384                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism gste  Gavia stellata (red-throated loon) Pathway gste04020   Calcium signaling pathway gste04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:gste00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     104259035 (RYR3)    04020 Calcium signaling pathway     104259035 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:gste04040]     104259035 (RYR3) Ion channels [BR:gste04040]  Voltage-gated cation channels   Ryanodine receptor    104259035 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD Motif Other DBs NCBI-GeneID:  104259035 NCBI-ProteinID:  XP_009812616 LinkDB All DBs Position Unknown AA seq 4836 aa AA seqDB search DDEVVLQCVASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCICNFVLEQSLSVR ALQEMLANTGDNASEGAAQGGGHRTLLYGHAILLRHSFSEMYLTCLTSSRSQTDKLAFDV GLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSMSNGSTQVDASF MQTLWNVHPTCSGSNITEGYLLGGHVVRFFHGHDECLTIPSTDQNDSQHKKVLYETGGAG VRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGKYLALNEDEGLAMLDREKSDTTSTA FCFRASKELKEKQDSSLKRDIDGMGVPEIKYGDSICFVQHVASALWLTYKAQDAKSARLG PLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQFISGNNRTLSPTALPVE EMAQTLQDLITYFQLPEEDLEHEDKQSKLRSLKNRQNLFKEEGMLALVLNCIDRLNDYNS AAHFAGIAREEHGTAWKEILNLLYKLLAALIRGNRNNCTQFSSNLDWLISKLDRLESSSG ILEVLHCILVESPEALNIIAEEHIKSIISLLDKHGRNYKVLDVLCSLCVCNGVAVRANQN LICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKWYFELIIDQVDPFLTAEP THLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRVPRAVASVNQHLLA SDDVVSCCLDLGVPSISFRINGQPVQGMFENFSIEGFFFPVVSLSAGVKVRFLLGGRHGE FKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGTTQFLSQASFIPCPIDTS QVALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKRHHPCLVEFSKLPETEKN YNLQMSTETLKTLLALGCHIVHAHPAAEEDLKKVKLPKNYMMSNGYKPAPLDLSEVKLLP SQELLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYALLDERTKKSNRDSL REAVRTFAGYGYSIEPPDQEIADQTVEKVSIDKIRFFRVEQSYAVKSGKWYFEFEAVTGG DMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGRSWQPGDVVGCMINLDDK SIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLSQIGRMNLGMDASTFKYYTMCG LQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEIWRIDGTIDSPPRLKVTHKTFG TQNSNSDMIYCRLSMPIEFRSSFNFGVGVENASSDVFQKRKHSQEIAAPSTTYFYSLRIF AGQDPSSVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRVHESVKRSNCYMVWGGDV IANSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTCYQVEPNTKLFPATFVQPTSTN LVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPVLWSRMPNSFLKVETERV SERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFHYHTLKLYSSVSALGNTR VAYVLCSHVDISQLFYTIDNQYLPGLLRSGFYDLLISIHLEHAKQAKLMMNNEFIIPVTD ETRTIKLYPDETKKHGLPGVGLSTCLKPGFNFSTPCFIVTSEERQTSSPEIPLDTLKSKA ISMLTEAVQCSGTHIRDPVGGQVAFQFVPVLKLIATLLIMGVFDDDDVKQVLLLIDPNVF GDHKQETEERTEKEEVTQVEDKAVEAGEKAIKETKAPARGLLQTRLPESVKLQMCHLLNY FCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQALNMSAALTAKKTKEFRSPPQEQ INMLLNFQLGEDCPCPEEIRDELYEFHDDLLIHCGIPLEEEEEEEEDSSLTGKLRSLMYK IKGPPKAEKVEPKEEEEKCPTTLKELISQTMVRWSQEDQIQDSELVRIMYTLLRRQYDSI GELLQALRKAYTISAASVKDTINLLAALGQIRSLLSVRMGKEEELLMINGLGDIMNNKVF YQHPNLMRVLGMHETVMDVMVNVLGGDKSQIVFPKMVASCCRFLCYFCRISRQNQKAMFE HLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALEEPDLDKVVTYLAGCGLQS CPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPDLR GEGGNGLLAAMQEAIRISENPTRDLPSQAYKREGDDEEEEEEEIVHMGNAIMSFYSALID LLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPLKLSTVNKDGTVNEPDMS ANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASASLDTVSLSTTEAALALN RYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRSLTKAQRDTIEECLLAIC HHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKYYCLPSGMGSYGIAAEEE LHLTEKLFWGIFDSLSHKKYDPELFRMALPCLSAIAGALPPDYLDTRIRSTLEKQTSVDP EGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAFDKTNSGWKYGVSLDENMKTHPLI RPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKEGGEVIIHQRENEKLRSISQSSQG NGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKKKKMELESKGGGSHPLLVPYDTLT AKEKSRDREKAQELFKFLQVNGIIISRGLNDMELDASSMEKRFAFKFLKKILKYVDSAQE FIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHCLYFLSSPTKTLSSSGYAS NKEKEMVASLFCKLAALVRHRISLFGSDSATMVNCLHILAQSLDTRTVMKSGSELVKAGL RAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHISQYQF GIDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPSLNH YNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGLIKEINDLAESGARYTEMPHVIEV ILPMLCNYLSYWWERGSESVPQSAGPCCTMITSEHLSIILGNILKIINNNLGIDEASWMK RIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIVMEEEQLRADSKTDTQEAELLILD EFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDELFRMVAEVFILWCKSHNFKREEQ NFVIQNEINNLAFLTGDTKSKMSKAMQVKSGGQDQERKKSKRRGDLYSIQTSLIVAALKK MLPIGLNMCTPGDQELISLAKTRYSHRDTDDEVKEHLRNNLHLQEKSDDPAVKWQLNLYK DILKTDEPADPERNVERVQRISAALYHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRM APLYNLPRHRSINLFLHGYQNYWIETEEYSFEEKLVQDLATPPKKDEEEEEETEKNQPDP LHQIILYFSRSALTERSKLEDDPLYIAYSAMMAKSCQEEEEEEEEEKEKTFEEKEMEKQR TLYQQARLHDRGAAEMVLQMISASKGHTGPMVVETLKLGIAILNGGNTIVQQKMLDYLKE KKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQHDEFTR DLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDV IDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMK LSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFF DMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQKQYIFNYVDFVERFHEPAKDIG FNVAVLLTNLSEHMPNDSRLQSLLEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISES SRMQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISETDSSERP EEEEEAEPCYVVDIGDDEEEEKSLESASAFSMACVAVKKNVANFFKMVTVKNLRKQYRKV RKMTVKEMVKVFFSFFWILFVGMFQLFFTIVWGIFQILWSTVFGGGLVEGAKNIKVTKIL GDMPDPTQFGIHDDVMEAEKAEGSEHGIRAELVQFVKGEKGEADIISDIFGIHTKKEGVS KHGHDAGLGDIAEILATDIQSSLENTVRKKKGLQIAEIAKEAETERKAEAEKADMEDGEK QDKAKEVQSEQLEEGKMKKKKRRHGQKFEKPEAVMANFFKALEIYKTKMLHYLARNFYNL RFLALFVAFAINFILLFYKVTEEPLDEVEEDSNLWNSFDEEEEEEGMVFFVLEESTGYMA PALRALAVIHTIISFVCVIGYYCLKVPLVVFKREKEVARKLEFDGLYITEQPSEDDIKGQ WDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFSPVDESEPEE ASLVSWLSSIDTKYHIWKLGVVFTDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFK TLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMT CYLFHMYVGVRAGGGIGDEIEDPAGDPYEIYRIVFDITFFFFVIVILLAIIQGLIIDAFG ELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDET EHTGQESFVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14511 nt NT seq  +upstreamnt  +downstreamnt gatgatgaagtagtacttcagtgtgttgccagtattcataaagaacaaaggaagttttgc ttggcagctgagggacttgggaatcgcctgtgctttttggaaccaacatcagaagctaaa tatgttcctccagacctttgcatctgtaatttcgtccttgaacagtccctatctgtcaga gcccttcaagaaatgctggccaacacaggggataatgctagtgaaggggcagctcaaggg ggtggtcacagaactctgctgtatggccatgctatactacttcgacattcgtttagtgaa atgtatttgacatgtttgacatcatcaagatcccaaacagataaacttgcatttgatgtg ggactacgagaaaatgcagcaggtgaggcatgctggtggacaatacaccctgcttctaaa caaaggtcagaaggagaaaaagttcgaataggtgatgatcttatcctggtcagtgtgtcc tctgaaagatacctgcatctctccatgtcaaatggaagtactcaggtggatgcctccttt atgcagacgctatggaatgtgcatcctacgtgctcaggaagcaatattacagaaggatat cttcttggtggacatgtagtacgttttttccatggccatgatgagtgtttgacaattcca tctacagatcagaatgattcacagcacaagaaagtgctttatgaaactggaggagctggc gttcgagcaaggtctttgtggagagtagaaccccttcgaataagctggagtggaagtaac atcagatggggacagcctttccgtcttcgacatattacaacaggaaagtacttggctctg aatgaagatgaaggacttgcaatgttagacagagaaaagtcagacacaacatctactgcc ttttgttttagagcatcaaaggagctaaaagaaaagcaggattctagtcttaaacgtgac attgatggaatgggagtccccgaaataaagtacggtgattcaatctgttttgttcaacat gtggctagtgccttgtggttgacttacaaagcacaagatgctaaatcagcacgtttaggt cccttgaaaagaaaggttatattacaccaagaaggccatatggatgatggtctaacctta caaagatgtcagcacgaggaatcccaggctgctcgaatcattcgcaatactacaagctta ttcagccagtttataagtggaaacaacagaacactatcacccactgccctgcctgttgag gagatggctcagactctgcaagacctgattacttacttccagcttcccgaagaagacctg gaacatgaagataagcaaagcaagcttcggtccctgaaaaacagacaaaatctattcaaa gaagagggaatgctggcactagttttgaattgcattgatcgcttaaatgactacaacagc gcagctcattttgcaggaattgcaagagaagaacatggtacagcatggaaagaaattctg aatctcctttacaaattgttagctgctctcattcgtggcaacagaaacaattgtactcag ttttccagtaacctcgattggctaataagtaaattggacagattagaatcttcctcaggt attttggaagtgttgcactgcatcttggttgaaagcccagaagctttaaatataatagct gaggagcacatcaaatccattatttcattgttggataaacacgggcgcaattacaaggtt ctggatgtgctttgctctctctgtgtctgtaatggagttgcagttcgtgccaatcaaaat ttgatctgtgacaatctactgcctcgaagagacttactcttgcaaacacgtttgattaat gatgtgacgagcataaggccaaacatatttttgggtgttgctgagggctctgcacaatac aagaagtggtactttgagttaataattgatcaggttgatccattcttgacggcagaacct acccatttacgagttggatgggcctctacttcaggttatgccccctatcctggaggtgga gaaggatggggaggcaatggtgttggtgatgacctgtactcttacggttttgatggcctt catctgtggtctggtcgagtacccagagctgtagcatctgtcaatcagcatttattagca tctgatgatgtggttagctgctgcttggatttaggtgtacccagtatttctttccgcatt aatggacagcctgtacaaggaatgtttgagaacttcagtatagaagggtttttcttccct gttgtaagcttatcagcaggtgtaaaagttcgtttcttattgggtggacgtcatggagag tttaaatttctgcctcctgctggctatgctccctgttatgaagcattgcttccaaaagag aagatgaaactggaaccagtgaaagaatataagagagattctgatggagtgagggatttg ctgggtacaacacaattcctctcccaagcttcctttatcccttgtccaatagacaccagt caggttgctcttccttttcatcttgaaaagatcagggacaaactagctgaaaatatccat gaactgtggggaatgaataaaatagaactgggctggacgtatggcaagatacgggatgat aataaaaggcatcatccttgtcttgtggagttctcaaaattacctgagacagagaagaat tataatctacaaatgtcaactgaaaccctcaaaacccttttggcccttggatgtcacatt gttcatgctcatccagcagctgaggaagatcttaaaaaagtcaaacttcctaaaaattac atgatgtcaaatggatataaacctgcccctcttgatctttctgaagtgaaattgttacct tctcaagaacttctagttgacaaactagcagaaaatgcacataatgtctgggcaaaagac agaataaagcaaggatggacctatggcattcagcaggatcttaagaacaaacgtaatcct cggctagtgccatatgcattattagatgaacgtactaaaaaatcaaacagagatagcctc cgtgaagctgttagaacatttgcgggctatggttatagtattgagccacctgaccaagag atagctgaccaaacagtggaaaaagtcagcattgacaagatacgatttttcagagtagaa cagtcttacgcagtgaagtctggaaagtggtactttgaatttgaagccgtgacaggtgga gatatgcgtgttggctgggccaggccaggctgtcgacctgacatagagttgggagctgat gaccaagcatttgtatttgaaggaagcaaaggccagcgttggcatcaaggcagtggattc tttggacgaagctggcaaccaggagacgtggttggttgtatgataaacttggatgacaaa tcaattatctttacactgaatggagagttgcttataaccagtaaaggttcagaacttgcg tttgctgacttcggaatagaaagtggttttgttccaatttgtgcactgggtctatctcag attggtcgtatgaaccttggaatggatgccagtacattcaagtattacacaatgtgtggc cttcaagaaggttttgaaccttttgctgtcaacatgaaccgagatgttgctatgtggttt agtaaacgcttaccaacatttgtcaatgtgccaaaaaatcatcctcacattgagatatgg agaattgatggaaccattgacagtcctcctcggttaaaagtaactcacaaaacatttggc acacagaatagcaattcagacatgatatattgtcgtttgagtatgcccattgagttccgc tcatcattcaactttggcgtgggtgtggaaaatgcctcatctgatgttttccaaaaacga aagcacagccaagaaattgctgctccttctactacgtatttttattcactacggatattt gctggccaagacccatcctctgtctgggttggctgggtaacaccagactatcatttttac agtgagaattttgacctaaataaaaattgtacagtgacagttactttaggtgatgagaga ggcagggttcatgaaagtgtgaagcgcagcaattgctatatggtttggggaggagatgta attgctaattctcagagatcaggtcgcagtaacgttgatttagaaattggatgctttgtt gacctggctactggaatgttgtcattcacagccaatggaaaagagcttggcacttgttat caggttgaaccaaacacaaagctttttccagcaacttttgtacagcctacgagcactaac ttggttcagtttgaacttggtaaattaaagaataccatgcctttatcagcagcaattttt aaaagtgaagaaagaaatcctgttcctcagtgtccccctcgccttgatgtgcaaacaatt acacctgttctatggagcaggatgccaaacagctttctaaaagtagaaactgagcgtgtc agtgaacgtcatggctgggttgtacagtgtttggaacctctgcagatgatggcacttcac atcccggaagaaaacagatgcgttgatattttggaactatgtgaacaagaagatttgatg aagtttcactaccacactttaaaactctatagctcagttagtgctctaggtaacactaga gttgcttatgtactttgtagccatgtggacatatctcagctattttatacaatagataac caatacttacctggactcctacgttctggattctacgacttgctcattagtattcatttg gagcacgccaagcaagccaagctcatgatgaacaatgaatttatcattccagttacagat gaaactcgaactattaaattatatcccgatgaaacaaagaagcatggtttacctggagtc gggcttagcacttgtctgaaaccaggctttaatttttctactccatgttttattgtgacc agtgaagaacgtcagacatccagcccagagataccccttgatacacttaaatccaaggcc ataagtatgctaacagaggcagtacagtgtagtggtactcatatacgagaccctgttgga ggacaggttgcattccagttcgttcctgttcttaaactgatagcaacattgctcataatg ggggtttttgatgatgatgatgtgaagcaggtgttactcctcattgatcccaatgtgttt ggagatcacaagcaagaaacagaagagaggacagagaaggaagaagttacacaagttgaa gataaagctgtagaagctggggagaaagcaataaaagaaacgaaagctcctgcaaggggc ttactgcagacaagattaccagaatctgttaagcttcagatgtgtcatttactcaattat ttctgtgactgtgagctacaacatagagtggaagcaattgtatcatttgcagaccgttat gtatcaaaattgcaatataatcagaaatacaggtacaatgaactcatgcaagccttgaac atgtctgctgctttgaccgccaagaagactaaagaatttcggtctcctcctcaagaacag attaatatgttgctgaattttcaactgggagaggattgtccctgtccagaggagattcgg gatgagttatatgaatttcatgatgatcttctaattcattgtggtattccactagaagag gaggaagaggaagaggaagattcctccttgactggcaaactccgttcattaatgtacaaa atcaaaggtccaccaaaagcagaaaaagtagaacctaaggaggaagaagagaaatgtcct actacattgaaagaactcatatctcagactatggtgcgctggtcccaggaagatcagatt caagattcagaattagttcggattatgtacactctccttcgtaggcaatatgacagcatt ggtgagctactgcaagctctgaggaaagcatacactattagtgctgcctctgtgaaggat accattaatctgcttgcagcactgggccagattcgctcacttctcagtgtcaggatggga aaagaggaggaattgctaatgattaatggattaggggatataatgaacaacaaggtgttt tatcagcatcctaacttaatgagagtcttgggcatgcatgagactgttatggatgtgatg gtgaatgtgcttggaggagataaatctcagatcgtttttcctaagatggtggcaagctgt tgtcgattcctgtgctacttctgtcgaattagtcgtcaaaaccaaaaggccatgtttgag catcttagttacttactggaaaacagcagtgttggactggcatttccttcaatgagaggt tcaacaccactagatgttgcagcagcctctgtaatggataacaatgagcttgcactagcg ttggaggagccagatctcgataaggttgttacctacctggcaggttgtggcctgcagagt tgtccagtattgctggctaaaggatatccagacattggatggaatccaatagagggtgaa cgttacctgtcattcttaagatttgcagtttttgttaatagtgaaagtgttgaggaaaat gcaagtgtcgttgtcaagctccttattcgacggccagagtgctttggaccagaccttagg ggagaaggaggaaatggtttgctggcagctatgcaggaagctatcaggatctcagagaat cctactcgcgaccttccctcacaggcatataaaagagaaggtgatgatgaggaggaggag gaggaggagattgtgcacatgggcaatgcaatcatgtcattttactcagctctcatagat ttacttggacgctgtgcaccagaaatgcatcttattcaaagtggaaaaggggaagctatt cgaatcaggtcaatccttcgatctctggtgccaactgaagatttggttgggattataagt ataccactaaagctgtcaacagttaacaaagatggcacagtgaatgagccagacatgtct gcaaatttctgtcctgatcataaagcacccatggtactcttcttggaccgtgtctatggt attaaggaccaaagcttcctccttcacctactggaagttggatttttaccagatttaaga gcctctgcctctttggatacagtttcgctaagtaccacagaggcagctctcgcactaaat agatatatttgctcagctgtgtttccattactcaaaagatgtgctcccctcttttctgga acagagcatcatgcctctctggttgactccatgcttcacacaatatacaggttatccaaa ggacgttccctcacaaaagcacaaagagacacgattgaagaatgccttcttgctatttgc caccacttacgtccctctatgctacaacagctgttgagaaggctagtttttgatgtgccc ctactcaatgaatactgtaaaatgcctctcaagcttctgacaaatcactatgaacagtgc tggaaatattattgtctgccttcaggaatgggaagctatggcattgcagcagaagaagaa ttacatttaactgaaaaacttttctggggaatatttgattccttgtctcataagaagtat gatccagagctctttcgaatggctctgccttgtctaagtgctatagctggtgccttgccc cctgattatttagatacacgaattaggtcaactttggaaaagcagacttcagtggatcca gaaggaaattttgatcccaaacctgtcagcacagcaaaccttgtacttcctgaaaagttg gagtatattgtcagcaagtatgctgaacattcccatgataaatgggcctttgataagact aatagtggatggaaatacggtgtttcactggatgaaaatatgaagactcacccattaata agacctttcaaaactttaactgaaaaggaaaaggaaatttatcgttggcctgccagagaa tcactgaaaaccatgttggccatgggatggagcctagaaaggaccaaggaaggaggagaa gtaataatacatcagcgtgaaaatgaaaagctccgcagcatatctcagtctagccaggga aatgggtatagcccggcaccacttgatctttctaatgtggtgctttctagggagcttcag ggaatggttgaggtaatggcagaaaactaccataatatatgggccaaaaagaagaaaatg gagttggaaagcaaaggtggaggtagtcatcctttattggtaccttatgacacattgaca gccaaggagaaatcacgggaccgtgaaaaggcacaagagctgtttaaattccttcaagtc aatggtataatcatatctcggggtctgaatgacatggagttggatgcttcatccatggaa aagaggtttgcctttaagtttctgaagaaaattttaaaatatgttgattctgctcaagag tttattgctcatttggaagccattgtaaccagtggaaaaactgaaaaatctccacatgac caagaaataaaattctttgccaaagttcttttaccattagttgatcagtactttacaaat cactgcctctacttcctgtcttctccaacaaaaacactcagtagcagcggatatgcatca aataaggaaaaggaaatggtagcaagcctgttctgcaaactagctgctcttgttagacat aggatctcactttttggtagtgattctgctacaatggtgaactgcctgcacatcttagca cagtctcttgacacacgaactgttatgaaatcaggatctgagcttgttaaagctggattg cgtgccttttttgaaaatgcagctgaagacctggaaaaaacttcagaaaatcttaaatta ggaaaatttacccattcacgaacacaaatcaagggtgtttcacagaatatcaattatact acggtagcattgttaccgatcttgacatcaatttttgaacatatttcacaatatcaattt ggaattgatttacttttgggggatgtacaagtttcatgttacagaattctctgtagcctc tattcccttgggactgggaagaacatctatgttgaaaggcagcgccccgcacttggtgag tgcttagcatctcttgcagcagccattccagtagcattccttgagccttctcttaaccat tacaacccattgtctgtcttcaacacgaaaagtgcaagagaaagagcaattttaggtatg cctgatacagtagaagagatgtgtccagagatccctcagttggatggactaataaaggaa attaacgatttagcagagtctggagcaaggtatactgaaatgcctcacgtaattgaggtt atcttacccatgctatgcaactatttatcctactggtgggaaagagggtctgagagtgtt cctcaaagtgctgggccttgctgtacaatgataacatctgagcatctgagcatcattctt ggaaacattctgaaaatcattaacaacaatctgggaatagatgaagcatcttggatgaaa agaattgcagtttatgctcaacccatcatcagcaaagccaggcctgatctgctcaaaacc cactttattccaacactggagaaattgaagaagaaagctataaagatcgtgatggaagag gagcaactgagagcagatagtaaaactgacacccaagaagctgagttactcattcttgat gagtttgctgttctttgtagagacctttacgccttctatccaatgttgatacgttatgta gacaacaacagagccaattggctaaagaaaccagatgcagattctgatgaactctttcga atggtagctgaagtttttatcctgtggtgtaaatcacataatttcaaaagagaagaacaa aattttgtgattcagaatgaaatcaacaatttggcatttttaacaggagacaccaagagc aagatgtctaaagccatgcaagtaaagtctggaggacaagatcaagagagaaagaaatca aaacgtagaggggatttgtactccatacaaacatccttgattgtagctgcacttaaaaag atgcttcctattggtttgaatatgtgtactcctggagatcaagagctcatctctttagct aagaccagatacagccatagggacactgatgatgaagtcaaagaacatttacgtaacaac ttacatttgcaagaaaagtctgatgatccagctgtgaaatggcagttaaatctgtacaaa gacattttgaagactgatgaacctgctgaccctgagagaaatgtggaacgtgtgcagagg atatcagctgctctgtatcatctggaacaggttgaacaaccactgaggtcaaagaaagct gtttggcacaaactcttgtcaaaacaacgcaaaagggctgttgttgcgtgtttcagaatg gcaccattatacaacctgccaaggcaccgttctattaacctcttcctccatggctatcag aactattggatagaaacagaggaatattcatttgaggagaaactagtgcaggatttggct acacctccaaagaaagatgaagaggaagaggaagagaccgagaaaaaccagcctgatcca cttcatcagattatcctctattttagtcgcagtgctctcacagaaagaagcaaactagaa gatgatcctttatatattgcctattccgccatgatggcaaagagctgtcaggaagaagaa gaagaggaagaagaagaaaaagaaaagacatttgaggagaaagaaatggaaaaacagaga actctctatcagcaagctcgcttacatgatcgtggagctgctgagatggtccttcagatg attagtgcaagcaaaggtcatacaggacccatggttgttgaaacactaaaacttggtatt gctattctaaatggtgggaataccatagttcaacagaaaatgctagattacctgaaggag aaaaaggatgctggattttttcaaagtctctctgggttgatgcagtcctgcagtgttctt gacttgaatgcgtttgagagacaaaataaagcagaaggcctgggaatggttactgaagaa ggaactctcatcgttcgtgaacgtggtgaaaaagtgttgcagcatgacgaatttactcga gatctatttagatttttacaactgctctgtgaagggcataacaatgattttcaaaattac ctacgtactcagatgggcaacaccacaacagtgaatattatcattagtacagttgactat ctcttgcgtcttcaggaatcaatcagtgacttctattggtactattcaggaaaggatgtc attgatgaatcaggacaacgtaacttctctaaagctttggctgtcaccaaacaaatattc aattcccttacagaatatatccagggcccttgcataggtaatcaacagagtctggctcat agtaggctgtgggatgcagttgttggcttccttcatgtctttgccaatatgcagatgaaa ctttcacaggactctgctcagattgaactgcttaaagaactgctagatctgctgaaggat atggtagtgatgctcttgtcactgcttgaaggtaacgttgtaaacggaactattggaaaa caaatggtagacacgcttgtagaatcatctagcaatgtagaaatgattttgaagttcttt gacatgttcctcaagttaaaagatctgactaactcagatgctttcaaagagcatgaccca gatgggaaaggcatcatttcaaagaaggaattccagaaatcaatggaggctcaaaaacaa tatatatttaactatgttgattttgtggaaagattccatgaaccagcaaaagacattgga tttaatgtagcagtattgctaacaaatctttcagagcatatgcctaatgattcacgcctt cagagcttacttgagcctgcagaaagtgttcttaattacttcgaaccataccttggccgt attgaaataatgggtggcgccaagaaaatagaaagagtttactttgaaatcagtgaatcc agtagaatgcagtgggagaagccacaggtgaaggaatccaaaaggcagttcatatttgat gttgtaaatgaaggtggagagcaagaaaaaatggaactctttgtgaatttctgtgaagac acgatctttgaaatgcagttagcatcccagatctctgaaactgattcatctgagaggcct gaggaagaggaagaggcagagccttgttatgtagtggatattggagatgatgaggaagaa gaaaagtccctggaatctgcttcagctttttcaatggcctgtgttgcagtgaagaagaat gttgccaacttttttaaaatggtcactgtgaagaacctaaggaaacaatacaggaaagtt agaaagatgacagtaaaagagatggtgaaagtgtttttctcctttttctggatcctattt gtagggatgttccaactgttctttactatagtgtggggaattttccagattctttggagc actgtatttgggggtggcctggttgaaggagccaaaaacattaaagttactaaaatatta ggggacatgcctgacccaacacagtttggaatccatgatgatgttatggaagcagaaaaa gctgaaggctctgagcatggcatcagagctgaacttgtgcagtttgtgaagggtgaaaag ggagaagctgacatcatctcagacatttttggcattcatacaaagaaagaaggtgtctca aaacatggtcatgatgctggacttggagatattgcagaaatccttgctactgatatccag tcatctttggaaaacacagttcgtaagaaaaaaggattacagatagctgaaatcgcaaaa gaagctgaaacagaaagaaaagcagaagctgagaaggctgacatggaagatggtgagaaa caagataaagcaaaggaagtacaatctgagcagctagaagagggaaaaatgaagaaaaag aagcgaaggcatggacaaaaatttgagaaaccggaggctgttatggctaacttcttcaaa gctttggaaatctataaaacaaaaatgcttcattacttggcaagaaatttttataactta aggtttcttgctctatttgttgcatttgccatcaactttattcttctgttttacaaggtg acagaagagccacttgatgaagtagaggaagactctaatctctggaactcttttgatgaa gaggaagaggaggaaggcatggtgttttttgttttagaagaaagtacaggttacatggca cctgctctcagagcattggcagttattcatactatcatctcctttgtctgtgtgattgga tactattgtttaaaggtccctctggttgtattcaagagagaaaaggaggtagctagaaag ctggaatttgatggactatacataactgaacagccatctgaagatgatattaaaggacaa tgggatcgcctggttataaatactccgtcctttcctaacaattactgggacaaatttgta aaacggaaggttattaacaagtacggagacttatatggagcagagcgcatagcagaactt ttgggtttggacaaaagtgcccttgattttagtccagtggatgagagtgaaccagaagag gcatctcttgtatcatggttaagctccattgatacaaagtaccacatctggaagctcgga gttgttttcactgataattcgtttttatacttagcttggtacacgacaatgtctatcctt gggcactacaacaacttcttctttgctgctcatctgctggatattgctatgggtttcaag acattgcgaaccattttgtcttcagttactcacaacggcaaacagcttgtgcttactgta ggactcctcgctgtagtagtatatctttacactgttgtggcgttcaacttcttccgcaag ttctacaacaaaagtgaagatgaagatgaaccagacatgaaatgtgatgacatgatgacg tgttacctgttccacatgtatgtcggtgtaagagctggtggtggcattggagatgaaatt gaggatcctgctggagacccttatgaaatctatcgaattgtctttgacatcacatttttc ttctttgtcattgttatcctactggccattattcaaggtctgattattgatgcttttggt gaattaagagaccagcaagaacaagtgagagaagatatggagaccaaatgttttatttgt ggaatcggcaatgactattttgacacaaccccacacggctttgaaacacatactttgcaa gaacacaacttggcaaactatctgttctttttaatgtatctcattaacaaggatgaaacg gagcatactggccaggagtcatttgtgtggaagatgtaccaagaaagatgttgggatttt ttcccagcaggggactgtttccggaaacagtatgaggatcaacttggctaa

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