Galeopterus variegatus (Sunda flying lemur): 103591905
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Entry
103591905 CDS
T08727
Symbol
TGFBR2
Name
(RefSeq) TGF-beta receptor type-2 isoform X1
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
gvr
Galeopterus variegatus (Sunda flying lemur)
Pathway
gvr04010
MAPK signaling pathway
gvr04060
Cytokine-cytokine receptor interaction
gvr04068
FoxO signaling pathway
gvr04144
Endocytosis
gvr04218
Cellular senescence
gvr04350
TGF-beta signaling pathway
gvr04380
Osteoclast differentiation
gvr04390
Hippo signaling pathway
gvr04520
Adherens junction
gvr04659
Th17 cell differentiation
gvr04926
Relaxin signaling pathway
gvr04933
AGE-RAGE signaling pathway in diabetic complications
gvr05142
Chagas disease
gvr05161
Hepatitis B
gvr05166
Human T-cell leukemia virus 1 infection
gvr05200
Pathways in cancer
gvr05202
Transcriptional misregulation in cancer
gvr05210
Colorectal cancer
gvr05212
Pancreatic cancer
gvr05220
Chronic myeloid leukemia
gvr05225
Hepatocellular carcinoma
gvr05226
Gastric cancer
gvr05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
gvr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
103591905 (TGFBR2)
04350 TGF-beta signaling pathway
103591905 (TGFBR2)
04390 Hippo signaling pathway
103591905 (TGFBR2)
04068 FoxO signaling pathway
103591905 (TGFBR2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
103591905 (TGFBR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
103591905 (TGFBR2)
09143 Cell growth and death
04218 Cellular senescence
103591905 (TGFBR2)
09144 Cellular community - eukaryotes
04520 Adherens junction
103591905 (TGFBR2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
103591905 (TGFBR2)
09152 Endocrine system
04926 Relaxin signaling pathway
103591905 (TGFBR2)
09158 Development and regeneration
04380 Osteoclast differentiation
103591905 (TGFBR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
103591905 (TGFBR2)
05202 Transcriptional misregulation in cancer
103591905 (TGFBR2)
09162 Cancer: specific types
05210 Colorectal cancer
103591905 (TGFBR2)
05212 Pancreatic cancer
103591905 (TGFBR2)
05225 Hepatocellular carcinoma
103591905 (TGFBR2)
05226 Gastric cancer
103591905 (TGFBR2)
05220 Chronic myeloid leukemia
103591905 (TGFBR2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
103591905 (TGFBR2)
05161 Hepatitis B
103591905 (TGFBR2)
09174 Infectious disease: parasitic
05142 Chagas disease
103591905 (TGFBR2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
103591905 (TGFBR2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
103591905 (TGFBR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gvr01001
]
103591905 (TGFBR2)
Enzymes [BR:
gvr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
103591905 (TGFBR2)
Protein kinases [BR:
gvr01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
103591905 (TGFBR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
ABC1
Haspin_kinase
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
103591905
NCBI-ProteinID:
XP_008572673
UniProt:
A0ABM0QWD2
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSDVEIEAQKDKTICPSCSRTVHPLRHFNND
MMVTDNNGAVKFSQLCKFCDVRFSTCDNQKSCTSNCSITSICEKPHEVCVAVWRKNDENI
TLETVCHDPKLPYHGFILEDAASPKCIMKEKKGFGETFFMCSCSTDECNDIIIFSEDYNN
SNPDLLLVIFQVTGVSLLPPLGIAIAVIITFYCYRVNRQQKLSPSWETSKPRKLMEFSDN
CAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVA
VKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWLITAFHAKGNLQE
YLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCL
CDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFKQTDVYSMALVLW
EMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCE
TLTECWDHDPEARLTAQCVAERFSELEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccaccgcacgttcagaagtcggatgtggaaatagaagcccagaaagat
aaaaccatctgcccaagctgtagtaggactgttcatccactgagacactttaataatgac
atgatggtcactgacaacaacggtgcagtcaagttttcacaactgtgtaaattttgtgat
gtgagattttccacttgtgacaaccagaagtcctgcacaagcaactgcagcatcacgtcc
atctgcgagaaaccgcacgaagtctgtgtggctgtatggagaaagaatgatgaaaacata
acactagagacggtttgccacgaccccaagctcccctaccatggatttattctggaagat
gctgcttctccaaagtgtattatgaaggaaaaaaaggggtttggcgagactttctttatg
tgctcctgtagcactgatgagtgcaatgacatcatcatcttctcagaagattataacaac
agcaatcctgacttgttgttagtcatcttccaagtgacaggcgtcagccttctgccgccg
ctaggaatcgccatagctgtcatcatcaccttctactgctaccgcgttaaccggcagcag
aagctgagcccgtcctgggaaaccagcaagcctcggaagctcatggagttcagcgataac
tgcgccatcattctggaggacgaccgctccgacatcagctccacgtgcgccaacaacatc
aaccacaacacagagctgctgcccattgagctggacaccctggtggggaaaggtcgcttc
gctgaagtctacaaggccaagctgaagcagaacacttcggagcagttcgagaccgtggcc
gtcaagatcttcccctacgaggagtacgcctcttggaagacggagaaggacatcttctcg
gacatcaacctgaagcatgagaacatactccagttcctgacggctgaggagcggaagact
gagttggggaaacagtattggctgatcactgctttccacgccaagggcaacctgcaggag
tacctgacgcgtcatgtcatcagctgggaggacctgcgcaagctgggcagctccctggcc
cggggcattgctcaccttcatagtgaccacaccccttgtgggaggcccaaaatgcccatc
gtgcacagggacctcaagagctccaatatccttgtgaagaatgacctgacctgctgtctg
tgtgactttgggctttccctgcgtttggaccctactctgtctgtggatgacctggctaac
agtgggcaggtgggaactgcaagatacatggccccagaagtcctagaatccaggatgaat
ctggagaatgttgagtccttcaagcagaccgatgtctactccatggctttggtactctgg
gaaatgacgtctcgttgtaacgcagtgggagaagtgaaagattatgagcctccatttggt
tctaaggtgcgggagcacccctgtgtggaaagcatgaaggacaacgtgttgagagatcga
ggacgaccagaaattcccagcttctggctcaatcaccagggcatccagatggtgtgtgag
acactgaccgagtgctgggaccacgacccagaggcccgtctcacagcccagtgtgtggca
gaacgcttcagcgagctggagcatctagacagactctcggggaggagctgctctgaggag
aagattcccgaagatggctcgctgaacactaccaagtag
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