Heterocephalus glaber (naked mole-rat): 101714832
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Entry
101714832 CDS
T02812
Symbol
Cacna1d
Name
(RefSeq) calcium voltage-gated channel subunit alpha1 D
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04010
MAPK signaling pathway
hgl04020
Calcium signaling pathway
hgl04022
cGMP-PKG signaling pathway
hgl04024
cAMP signaling pathway
hgl04218
Cellular senescence
hgl04260
Cardiac muscle contraction
hgl04261
Adrenergic signaling in cardiomyocytes
hgl04270
Vascular smooth muscle contraction
hgl04530
Tight junction
hgl04713
Circadian entrainment
hgl04723
Retrograde endocannabinoid signaling
hgl04724
Glutamatergic synapse
hgl04725
Cholinergic synapse
hgl04726
Serotonergic synapse
hgl04727
GABAergic synapse
hgl04728
Dopaminergic synapse
hgl04911
Insulin secretion
hgl04912
GnRH signaling pathway
hgl04921
Oxytocin signaling pathway
hgl04924
Renin secretion
hgl04925
Aldosterone synthesis and secretion
hgl04927
Cortisol synthesis and secretion
hgl04929
GnRH secretion
hgl04930
Type II diabetes mellitus
hgl04934
Cushing syndrome
hgl04935
Growth hormone synthesis, secretion and action
hgl04973
Carbohydrate digestion and absorption
hgl05010
Alzheimer disease
hgl05020
Prion disease
hgl05022
Pathways of neurodegeneration - multiple diseases
hgl05031
Amphetamine addiction
hgl05207
Chemical carcinogenesis - receptor activation
hgl05410
Hypertrophic cardiomyopathy
hgl05412
Arrhythmogenic right ventricular cardiomyopathy
hgl05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101714832 (Cacna1d)
04020 Calcium signaling pathway
101714832 (Cacna1d)
04024 cAMP signaling pathway
101714832 (Cacna1d)
04022 cGMP-PKG signaling pathway
101714832 (Cacna1d)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
101714832 (Cacna1d)
09144 Cellular community - eukaryotes
04530 Tight junction
101714832 (Cacna1d)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
101714832 (Cacna1d)
04929 GnRH secretion
101714832 (Cacna1d)
04912 GnRH signaling pathway
101714832 (Cacna1d)
04921 Oxytocin signaling pathway
101714832 (Cacna1d)
04935 Growth hormone synthesis, secretion and action
101714832 (Cacna1d)
04924 Renin secretion
101714832 (Cacna1d)
04925 Aldosterone synthesis and secretion
101714832 (Cacna1d)
04927 Cortisol synthesis and secretion
101714832 (Cacna1d)
09153 Circulatory system
04260 Cardiac muscle contraction
101714832 (Cacna1d)
04261 Adrenergic signaling in cardiomyocytes
101714832 (Cacna1d)
04270 Vascular smooth muscle contraction
101714832 (Cacna1d)
09154 Digestive system
04973 Carbohydrate digestion and absorption
101714832 (Cacna1d)
09156 Nervous system
04724 Glutamatergic synapse
101714832 (Cacna1d)
04727 GABAergic synapse
101714832 (Cacna1d)
04725 Cholinergic synapse
101714832 (Cacna1d)
04728 Dopaminergic synapse
101714832 (Cacna1d)
04726 Serotonergic synapse
101714832 (Cacna1d)
04723 Retrograde endocannabinoid signaling
101714832 (Cacna1d)
09159 Environmental adaptation
04713 Circadian entrainment
101714832 (Cacna1d)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
101714832 (Cacna1d)
09164 Neurodegenerative disease
05010 Alzheimer disease
101714832 (Cacna1d)
05020 Prion disease
101714832 (Cacna1d)
05022 Pathways of neurodegeneration - multiple diseases
101714832 (Cacna1d)
09165 Substance dependence
05031 Amphetamine addiction
101714832 (Cacna1d)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
101714832 (Cacna1d)
05412 Arrhythmogenic right ventricular cardiomyopathy
101714832 (Cacna1d)
05414 Dilated cardiomyopathy
101714832 (Cacna1d)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101714832 (Cacna1d)
04934 Cushing syndrome
101714832 (Cacna1d)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hgl04040
]
101714832 (Cacna1d)
Ion channels [BR:
hgl04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
101714832 (Cacna1d)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
101714832
NCBI-ProteinID:
XP_012920838
LinkDB
All DBs
Position
Un
AA seq
1877 aa
AA seq
DB search
MVPLLHIALLVLFVIIIYAIIGLELFIGKMHKTCFFADSDIVAEEDPAPCAFSGNGRQCT
ANGTECRSGWVGPNGGITNFDNFAFAMLTVFQCITMEGWTDVLYWVNDAIGWEWPWVYFV
SLIILGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAED
IDPENEEEGGEEGKRNTSMPTSETESVNTENVSGEGETKGCCRRLCQAISKSKLSRRWRR
WNRFNRRRCRAAVKSVTFYWLVIVLVFLNTLTISSEHYNQPGWLTQIQDIANKVLLALFT
CEMLIKMYSLGLQAYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIF
KVTRHWTSLSNLVASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRST
FDNFPQALLTVFQILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVF
LAIAVDNLADAESLNTAQKEEAEEKERKKIARKESLENKKNHKPEVNQIANSDNKVTVDD
YREEDEDKDPYPPCDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFF
ILSKTNPIRVGCHKLINHHVFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFT
AIFTVEILLKMTTFGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDE
AKSNPEECRGLFILYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALL
YKAIDSNGENVGPVYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCE
LDKNQRQCVEYALKARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHY
EQSKMFNDAMDILNMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALS
EADNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFF
IYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCD
PESDYNPGEEYTCGSSFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHL
DEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDG
TVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVT
VGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDL
QDDEPEEKREEEDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPASDT
EKPLFPPAGNSVCHSRPNRNSVGKQVPTSTNANLNNANMSKAAHGKRPSTGDLEHVSENG
HHSSHKHDREPPRWSSIKRTRYYEMYIRSDSGDEQFPTICREDPEIHGYFRDPRCLGEQE
YFSSEECYEEDSSPTWSRQNYSCYNRYLGGTTDFERPRGYHPPQGCSEDDDSPVCYDSRR
SPRRRLLPPTPPPHRRSSFNFECLRRQSSQEEAPPSPTLPHRTALPLHLMQQQIMAVAGL
DSSRAPKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVERSESLDQVNGSLPSLHRSSW
YTDEPDISYRTFTPASLTVPSRFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSAT
KHEIADACDLTIDEMESAASTLLNGSMGPRASGDVGLVSHRQDYELQEFGPGYSDEEPDP
GRDEEDLADEMICITTL
NT seq
5634 nt
NT seq
+upstream
nt +downstream
nt
atggttcccctccttcacatagcccttttggtattatttgtaatcataatctatgctatt
ataggattggaactttttattggaaaaatgcacaaaacatgtttttttgctgactcagat
atcgtagctgaagaggacccagctccatgtgcgttctcagggaatggacgccagtgtact
gccaatggcacagaatgtaggagtggctgggttggcccaaacggaggcatcaccaacttt
gataactttgcctttgccatgctcactgtgtttcagtgtatcaccatggagggctggacg
gatgtgctgtactgggtaaatgatgcgataggatgggaatggccatgggtgtattttgtt
agtctgatcatccttggctcatttttcgtccttaacctggttcttggtgtccttagtgga
gagttctcaaaggaaagagagaaggctaaagcacggggagacttccagaagctacgggaa
aagcagcagctggaagaggatctcaagggctacttggattggatcactcaggcagaagac
attgatcctgagaacgaggaggagggtggagaagaaggcaaacgcaatactagcatgccc
accagcgagactgaatctgtgaacacagagaacgtgagtggcgaaggcgagaccaagggc
tgctgcagacgtctctgtcaagccatctcaaaatccaaactcagccgacgctggcgtcgc
tggaaccgattcaatcgtagaagatgtagggctgctgtgaagtctgtcacattttactgg
ctggttattgtcctggtgtttctcaacacgttaaccatttcctctgagcactacaatcag
cccggctggttgacacagattcaagatattgccaacaaagtcctcttggccctgttcacc
tgtgagatgctgataaaaatgtacagcttgggtctccaggcgtatttcgtgtctcttttc
aaccggtttgactgcttcgtggtatgtggtgggattaccgagaccatcttagtggagctg
gaaatcatgtctccgctggggatttccgtgtttcggtgtgtgcgcctcttaagaatcttc
aaagtgaccaggcactggacttctctcagcaacttggtggcatccctgttaaactccatg
aagtctatcgcttcactgttgcttttgctttttctcttcattatcatcttttccttgctt
gggatgcagctgtttggtgggaagtttaatttcgatgaaacgcaaaccaagcgaagcacc
ttcgacaactttcctcaagcactgctgaccgtattccagattctgacaggtgaagactgg
aatgctgtgatgtatgacggcatcatggcttatggaggcccatcctcttcgggaatgatt
gtctgcatctacttcatcatcctcttcatctgtggtaactatattctactgaatgtcttc
ctggccattgctgtagacaacttggctgatgctgaaagtttgaacactgcccaaaaagag
gaagctgaagaaaaagaaaggaaaaagattgccagaaaagagagcctagaaaataaaaag
aaccacaaaccagaagtcaaccaaatagccaacagtgacaacaaggttacagttgatgac
tatcgagaggaagatgaggacaaggacccttacccgccttgtgatgtgccagtaggtgaa
gaggaagaggaggaggaggaggatgaacctgaagttcccgctggtccccgccctcgcaga
atctcagagttgaacatgaaggagaaaatcgcccccatccctgaagggagtgctttcttc
attctcagcaagaccaacccgatccgtgtgggctgccacaagctcatcaaccaccacgtc
ttcaccaacctcatcctcgtcttcatcatgctgagcagcgctgccctggccgcggaggac
cccatccgcagccactccttccggaacactatactgggttactttgactatgctttcaca
gccatctttactgttgaaatcctgttaaagatgacgacttttggagctttcttgcacaaa
ggggctttctgcaggaactacttcaatttgctggacatgctagttgttggtgtgtctctg
gtgtcatttgggattcaatccagtgccatctctgttgtgaagattctgagggtcttaagg
gtcttgaggccccttagagccatcaacagagcaaaaggacttaagcacgttgtccagtgc
gtcttcgtggccatccggacaattggcaacatcatgatcgtcactaccctcctccagttc
atgtttgcctgcattggggtgcagttgttcaaggggaagttctatcgctgcacagacgaa
gccaaaagtaaccctgaagagtgcagagggcttttcatcctctacaaggatggagacgtc
gatagccccgtggtccgtgaaaggatctggcaaaatagtgatttcaactttgacaacgtc
ctttctgctatgatggcactcttcacggtctccacttttgagggctggcctgcgttgcta
tacaaagccattgactcaaatggagaaaacgttggcccagtctacaactaccgcgtggag
atctccatcttcttcatcatctatatcatcattgtcgcgttctttatgatgaacatcttt
gtgggctttgtcattgttacatttcaggagcagggagaaaaagagtataagaactgtgag
ctggacaaaaatcagcgtcagtgtgtcgaatacgccttgaaagcacgtcccttgcggaga
tacatccccaaaaacccctaccagtacaagttctggtacgtggtaaactcttcgcctttc
gaatacatgatgttcgtcctcatcatgctcaacacactctgcttggccatgcagcactac
gagcagtccaagatgttcaatgacgccatggacattctgaacatggtcttcactggggtg
ttcactgttgaaatggttttgaaagtcattgcatttaagcctaaggggtattttagtgac
gcctggaacacgtttgactccctcatcgtaatcggcagcattatagacgtggccctcagc
gaagcagacaactctgaagagagcaatagaatctccatcacctttttccgtcttttccga
gtgatgcgactggtgaagcttctcagcaggggggaaggcatccggacattgctgtggact
tttattaagtccttccaggcactcccgtatgtcgccctcctcattgccatgctgttcttc
atctacgccgtcatcggcatgcagatgtttgggaaagttgccatgagagataataaccag
atcaacaggaacaacaacttccagacgtttccccaggcagtgctgctgctcttcaggtgt
gctactggcgaggcttggcaggagatcatgctggcctgcctcccaggaaagctatgtgat
cccgagtcagactacaaccccggagaggagtacacatgcggcagcagctttgccatcgtc
tatttcatcagcttttacatgctctgtgcgtttctgatcatcaatctgtttgtggctgtc
atcatggacaattttgactatctgacccgggactggtctattttagggcctcaccactta
gatgaattcaaaagaatatggtcagaatatgaccctgaggcaaagggaaggataaaacac
ctcgacgtggtcacactgctccggcgcatccagcctcctctgggatttgggaaattatgc
ccacaccgagtagcgtgtaagaggttagttgccatgaacatgcctctcaacagtgatgga
acagtcatgtttaacgcaaccctgtttgctttggtccgaacagctctcaagatcaagact
gaagggaacctggaacaagctaatgaagaacttcgagctgtgataaagaaaatctggaag
aaaaccagcatgaaactgctcgaccaagttgtccctcctgctggtgatgatgaggtaacc
gtggggaagttctatgccactttcctgatacaggactactttaggaaattcaagaaacgg
aaagaacaaggattggtgggaaaataccctgcgaagaacaccacaattgccctacaggca
ggattaaggacactgcatgacattgggccagaaatccggcgtgctatatcctgtgatttg
caagatgatgagccagaggaaaagagagaagaagaagatgtattcaaaagaaatggtgcc
ctgcttggaaaccatgtcaatcatgttaatagtgataggagagattcccttcagcagacc
aataccacccaccgtcccctgcatgtccaaaggccttcaattccacctgcgagtgatact
gagaaaccgctgtttcctccagcaggaaattcggtgtgtcatagccgtcctaaccgtaat
tccgtaggaaagcaagttcccacctcaacaaatgccaatctcaacaatgccaacatgtcc
aaagctgcccatggaaagcgacccagcactggggaccttgagcatgtgtctgaaaatggg
catcattcctcccacaagcacgaccgggagcctccaagatggtccagtattaaaagaacg
cgctattatgaaatgtacattaggtccgactcaggggatgagcagttcccaactatttgc
cgagaggacccagagatacacgggtacttcagggacccccgctgcttgggggagcaggag
tacttcagtagcgaggagtgctatgaggaagacagctctcccacctggagcaggcaaaac
tacagctgctacaacaggtacctgggcggcaccacggacttcgagaggccccgaggctac
cacccaccccaaggctgctcggaggacgatgactcgcctgtctgctatgactctcggaga
tctccccggagacgcctactacctcccacccccccaccccaccggagatcctccttcaac
ttcgaatgtctgcgccggcagagcagccaggaggaggccccgccttcccccaccctgccg
caccgcacggccctgcctctgcatctgatgcagcagcagatcatggcagttgcaggcctc
gactcaagtagagccccgaagtactcaccgagccactcaacccggtcgtgggccacccct
ccagcaactcctccatacagggactggacaccgtgctatacccccctgatccaggtggag
cggtcagagtccctggaccaggtcaacggcagcctgccctccctgcaccgcagctcctgg
tacacggacgagcctgacatctcctatcggactttcacaccagccagcctgactgtcccc
agcagattccgtaacaagaacagcgacaagcagaggagtgcagacagcttggtggaggca
gtcctgatatccgaaggcttaggacgctatgcaagggacccaaaatttgtgtcagcgact
aaacatgaaatcgctgatgcctgtgacctaaccattgatgagatggagagtgcagccagc
accctgctcaacgggagcatgggtcctcgggccagtggggatgtgggccttgtctctcac
cggcaggactacgagctccaggagtttgggcccggctacagtgacgaggagccagaccct
gggcgagatgaggaggacctggctgatgaaatgatctgtatcaccaccttgtag
DBGET
integrated database retrieval system
