Heterocephalus glaber (naked mole-rat): 101726029 Help Entry 101726029         CDS       T02812                                  Symbol Kdr Name (RefSeq) kinase insert domain receptor   KO K05098   kinase insert domain protein receptor [EC:2.7.10.1] Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl01521   EGFR tyrosine kinase inhibitor resistance hgl04010   MAPK signaling pathway hgl04014   Ras signaling pathway hgl04015   Rap1 signaling pathway hgl04020   Calcium signaling pathway hgl04151   PI3K-Akt signaling pathway hgl04370   VEGF signaling pathway hgl04510   Focal adhesion hgl04517   IgSF CAM signaling hgl05205   Proteoglycans in cancer hgl05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     101726029 (Kdr)    04014 Ras signaling pathway     101726029 (Kdr)    04015 Rap1 signaling pathway     101726029 (Kdr)    04370 VEGF signaling pathway     101726029 (Kdr)    04020 Calcium signaling pathway     101726029 (Kdr)    04151 PI3K-Akt signaling pathway     101726029 (Kdr)   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     101726029 (Kdr)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     101726029 (Kdr)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     101726029 (Kdr)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     101726029 (Kdr)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     101726029 (Kdr)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hgl01001]     101726029 (Kdr)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:hgl04090]     101726029 (Kdr) Enzymes [BR:hgl01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      101726029 (Kdr) Protein kinases [BR:hgl01001]  Receptor tyrosine kinases (RTK)   VEGFR family [OT]    101726029 (Kdr) CD molecules [BR:hgl04090]  Proteins   101726029 (Kdr) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr VEGFR1-3_N_Ig-like Pkinase Ig_3 I-set VEGFR-1-like_Ig-like Ig_2 ig Ig_VEGFR-1-like_5th VEGFR-2_TMD V-set Izumo-Ig C2-set_2 Ig_5 Haspin_kinase ABC1 Ig_PDGFR_d4 Motif Other DBs NCBI-GeneID:  101726029 NCBI-ProteinID:  XP_004849899 UniProt:  A0AAX6PF03 LinkDB All DBs Position Un AA seq 1211 aa AA seqDB search MESKALLTLALWFCVETGATSVGLPSVALDPPSLSIQKNILAIMANTTLHITCRGQRDLD WLWPNNQSGSEERVEVTECSDDLFCKTLRIPKVIGNDTGAYKCFYRDTNVTSVVYVYVQD YRSPFIASVSDEHDVVYITENKNKSVVVPCRGSISNLNVSLYARYPERRFVPDGNRIFWD SEKGFTIPGYMISYAAMVICEAKINDENYQSIVYIVVVVGYKIYDVVLSPPHGIELSVGE KLVLNCTAKTELNVGLVFSWQCPSLKMFFGKESEVKSKSAWPVPPQIGEKALISPMDSYQ YGTTQTLTCTVYANPPLHHIHWYWQLEEECSYEPSQAVLTANPYICKEWRTVEDFQGGNK IEVNKNQYALIEGRNKTVSTLVIQAANVSALYKCEAVNKAGRGERVISFHVTKGPEITLQ PTTQPTEQESVSLWCHADRATLESLTWYKVGPQPPLVHMEEQLTPICKNLDALWKLNATM FSNSTNDILVMEFQNVSLQDQGEYVCSAQDRKTKKKHCMVWQLTVLERMAPVITGNLENQ TTSIGETIEVACTAFGNPPPQITWFKDNETLVEDSGIVLKDGNQNLTIRRVRKEDEGLYT CQACNVLGCSRVETFFIIEGAQAKTSLEVIILVGTAVIAMFFWLLLVIILRTVKRASEGE LKTGYLSIVMDSDELPLDEHCERLPYDANKWEFPRDRLKLGKPLGRGAFGQVIEADAFGI DKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIV EFCKFGNLSTYLRGKRNEFVPYKTKGARFRQGKDYVGEISVDLKRRLDSITSSQSSASSG FVEEKSLSDVEEEEASEELYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILL SEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLW EIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHEEPSQRPTFSEL VEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVSCMEEEEVCDPKFHYDN TAGISQYLQNNKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDSGMVLASEELKTLEDRT KLAPSFSGMKPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYSSEEAELLKLVEATQQP DSGTVLSSPPA NT seq 3636 nt NT seq  +upstreamnt  +downstreamnt atggagagcaaggcgctactgaccctcgccctgtggttctgtgtggagaccggggccacc tctgtgggtttgcctagtgttgcccttgatccacccagcctcagcatacaaaagaatata cttgcaattatggccaatacaactcttcacattacttgcagggggcagcgggacttagac tggctatggcccaacaatcagagtggttctgaggaaagggtggaggtgacggagtgcagt gatgatttattttgcaagacactcaggattccaaaagtgataggaaatgatactggagct tacaagtgcttctaccgagacaccaacgtgacctcagttgtttacgtctacgttcaagat tacagatcacccttcattgcttctgttagtgatgagcatgacgttgtgtacattactgag aacaaaaataaaagtgtggtggttccatgtcgtgggtccatttcaaacctcaacgtgtca ctttatgcaaggtaccctgaaaggaggtttgttcctgatggaaacagaattttctgggac agtgagaaaggctttactattcccggctacatgatcagctatgctgccatggtcatttgt gaagcaaaaattaatgatgaaaattaccagtcgattgtgtacatagttgtggttgtaggg tataagatttatgatgtggttctgagccctcctcatggaattgagctatctgttggagag aagcttgtcttaaattgtacagcaaaaactgagctaaacgtggggcttgtcttcagctgg cagtgcccttctttgaagatgttctttggaaaagaaagtgaggtaaaatcaaagtcagct tggccagtcccaccccagattggcgagaaggccctgatctcgcccatggattcctaccag tatggtaccacacagacgctgacatgcactgtctatgccaaccctcccctgcatcacatc cactggtactggcagttggaggaagagtgctcctacgagcccagccaagctgtcttaaca gcaaacccatatatttgtaaagaatggagaactgtggaggatttccagggggggaataaa attgaagtcaacaaaaatcaatatgccctaattgaaggaagaaacaaaactgtaagtact cttgtcatccaagctgcaaatgtgtcagctttatacaaatgtgaagccgtcaacaaagct gggagaggagagagggttatatccttccatgtgaccaagggtcctgaaattactttgcaa cctaccacccagccaactgagcaggaaagtgtgtctctgtggtgtcacgcagacagagca acactggagagcctcacatggtataaggttggcccacagcctccattggtccacatggaa gagcagcttacacctatttgcaagaacttggatgctctttggaaactgaatgccaccatg ttctctaatagcacgaatgacattttggtcatggagttccagaatgtgtccttgcaggat caaggagaatatgtctgctctgctcaagacaggaaaaccaagaaaaaacattgcatggtc tggcagctcacagtcctagagcgcatggcacctgtgatcacaggaaaccttgagaatcag acgacaagtattggcgaaaccatcgaagttgcctgcacagcatttgggaacccccctcca cagattacctggtttaaagataatgagacacttgtggaagactcaggcattgtactgaaa gatgggaaccagaacctaaccatccgcagagtgaggaaagaggatgaaggcctctatacc tgccaggcctgcaatgttcttggatgttcaagagtggagacatttttcatcatagaaggt gcccaggcaaagaccagcttggaagtcattattctagtaggcactgcggtgattgccatg ttcttctggctacttcttgtcatcattctacggaccgttaagcgggccagtgaaggagaa ctgaagacaggctacttgtccattgtcatggattccgatgaactgcccctggatgaacac tgtgaacgcttgccttatgatgccaacaaatgggaattccccagagaccggctgaaacta ggtaaacctcttggccgtggtgcctttggccaagtgattgaggcagatgcttttggaatt gacaagacagcaacttgcaagacagtggctgtcaaaatgttgaaagaaggagcaacacac agtgaacaccgagctctcatgtctgaactcaagatcctcattcatattggccaccatctc aatgtggtcaaccttctaggtgcctgtaccaagccaggagggcctctcatggtgattgtg gaattctgcaaatttgggaacctatcaacttatctacggggcaagagaaatgaatttgtc ccctacaagaccaaaggggcacggttccgtcaagggaaagactatgttggagaaatctct gtggatctgaaacgccgtttggacagtatcaccagtagccagagctcagccagctctggg tttgttgaagagaagtccctcagtgatgtggaggaagaagaagcttctgaagagctgtac aaggactttctgaccttggaacatctcatctgctacagcttccaagtggctaagggcatg gagttcttggcatcacgtaagtgtatccacagggacctggcagcacgaaatatcctcttg tcggagaagaacgtggtcaaaatctgtgactttggcttggcccgagacatctataaggat ccagattatgttagaaaaggagatgcccgcctccctttgaaatggatggccccagaaaca atttttgacagagtgtacacaattcagagtgatgtgtggtcttttggtgttttgctgtgg gaaatattttccttaggtgcttccccatatcctggggtaaagattgatgaagaattttgc aggcgattaaaagaaggaactagaatgcgggcccctgattataccacaccagaaatgtac cagactatgcttgattgctggcatgaggagcccagtcagagacccacgttttctgagttg gtggaacacttgggaaatcttctacaggctaatgctcagcaggatggcaaagactacatt gttcttccaatatcagagactttgagcatggaagaggattctggactctctctgcctact tcacctgtttcctgtatggaggaagaggaagtatgcgaccccaaattccattatgacaac acagcaggaatcagtcagtatctgcagaacaataagcgaaagagccggccagtgagtgta aaaacatttgaagatatcccattggaagaaccagaagtaaaagtaatcccagatgacaac cagacggacagtggtatggttcttgcatcagaagagctgaaaactttggaagacagaacc aaattagctccatctttcagcggaatgaagcccagcaaaagcagggagtccgtggcatct gaaggctccaaccagaccagcggctaccagtcggggtatcactcagatgacacagacacc actgtgtactccagtgaggaggcagaacttttaaagctggtagaggctacacaacagcct gactctgggactgtgttaagctctcctcctgcttaa

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