Harpia harpyja (harpy eagle): 128139698 Help Entry 128139698         CDS       T10541                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism hhar  Harpia harpyja (harpy eagle) Pathway hhar04020   Calcium signaling pathway hhar04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:hhar00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     128139698 (RYR3)    04020 Calcium signaling pathway     128139698 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:hhar04040]     128139698 (RYR3) Ion channels [BR:hhar04040]  Voltage-gated cation channels   Ryanodine receptor    128139698 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 MIR Ins145_P3_rec SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 NodZ TBK1_ULD Motif Other DBs NCBI-GeneID:  128139698 NCBI-ProteinID:  XP_052638427 LinkDB All DBs Position 3:complement(47184894..47437017) Genome browser AA seq 4864 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDDASEGAAQGGGHRTLLYGHAILLRHSFSEMYL TCLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER YLHLSMSNGSIQVDASFMQTLWNVHPTCSGSNITEGYLLGGHVVRLFHGHDECLTIPSTD QNDSQQKKVLYETGGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGKYLALNED EGLAMLDREKSDTTSTAFCFRASKELKEKQDSSLKRDIDGMGVPEIKYGDSICFVQHVAS ALWLTYKAQDAKSARLGPVKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTSLFSQ FISGNNRTLSPSALPIEEMAQTLQDLITYFQLPEEDLGHEDKQSKLRSLKNRQNLFKEEG MLALVLNCIDRLNDYNSAAHFAGIAREEHGTARKEILNLLYKLLAALIRGNRNNCTQFSS NLDWLISKLDRLESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYKVLDV LCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW YFELIIDQVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW SGRVPRAVASVNQHLLASDDVVSCCLDLGVPSISFRINGQPVQGMFENFSTEGFFFPVVS LSAGVKVRFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRDLLGT TQFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRDDNKR HHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHAHPAAEEDLKKVKLPKNYMMS NGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRNPRLV PYALLDERTKKSNRDSLREAVRTFAGYGYSIEPPDQEIADQTVEKVSIDKIRFFRVERSY AVKSGKWYFEFEAVTGGDMRVGWARPGCRPDIELGADDQAFVFEGSKGQRWHQGSGFFGR SWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIESGFVPICALGLAQIGR MNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEIWRID GTIDSPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFRSSFSFGMGVENASSDVFQKRKHS QEIAAPCTTYFYSLRIFAGQDPSSVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDERGRV HESVKRSNCYMVWGGDVIANSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGSCYQVE PNTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQTITPV LWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMKFH YHTLKLYSSVSALGNTRVAYALCSHVDISQLFYTIDNQYLPGLLRSGFYDLLISIHLEHA KQAKLMMNNEFIIPVTDETRTIKLYPDETKKHGLPGVGLSTCLKPGFNFSTPCFIVTSEE HQTSSPEIPLDTLKSKAISMLTEAVQCSGTHIRDPVGGQVAFQFVPVLKLIATLLIMGVF DDDDVKQVLLLIDPNVFGDHKEETEERTEKEEVTQVEEKAVEAGEKAVKETKAPAKGLLQ TRLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADCYVSKLQYNQKYRYNELMQALNMSA ALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYEFHDDLLIHCGIPLEEEEE EEEDSSLTGKLRSLMYKIKGPPKAEKVEPKEEEEKSPTTLKELISQTMVRWSQEDQIQDP ELVRIMYTLLRRQYDSIGELLQALRKAYTISAASVKDTINLLAALGQIRSLLSVRMGKEE ELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDKSQIIFPKMVASCCRF LCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELALALEE PDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEENASV VVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPTRDLPSQAYKREGDDGEEEEIV HMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGIISIPLKL STVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPDLRASASL DTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRLSKGRSLT KAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYEQCWKYYC LPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKKYDPELFRMALPCLSAIAGALPPDYLD TRIRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAFDKTNSGWK YGISLDENMKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERAKEGGEAIIHQ RENEKLRSISQSSQGNGYSPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKKKKMELESK GGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMDLDASSMEKRFAF KFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHCLYF LSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDSATMVNCLHILAQSLDT RTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALL PILTSIFEHISQHHFGIDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASL AAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGLIKEINDLA ESGARYTEMPHVIEVILPMLCNYLSYWWERGSESLPQSAGPCCTMITSEHLSIILGNILK IINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIVMEEEQLRA DSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDADSDELFRMVAEV FILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKSGGQDQERKKSKRRGDLYSIQ TSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDDEVKEHLRNNLHLQEKSDDP AVKWQLNLYKDILKSDEPTDPERNVERVQRISAALYHLEQVEQPLRSKKAVWHKLLSKQR KRAVVACFRMAPLYNLPRHRSINLFLHGYQNYWIETEEYSFEEKLVQDLATPPKKEEEEE EETEKKQPDPLHQIILYFSRSALTERSKLEDDPLYIAYSAMMAKSCQEEEEEEEEEKEKT FEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHPGPMVVETLKLGIAILNGGNTIV QQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGE KVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTVDYLLRLQESISD FYWYYSGKDIIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGF LHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESS SNVEMILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQKQYIQSEIEFLL SCAEADENDMFNYVDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRLQSLLEPAESVLN YFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESKRQFIFDVVNEGGEQEKME LFVNFCEDTIFEMQLASQISETDSSERPEEEEEAEPCYVVDIGDDEEEEKSLESASAFAM ACVAVKKNVANFFKMATVKNLRKQYRKVRKMTVKEMVKVFFSFFWILFVGMFQLFFTIVW GIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDVMEAEKAEGAEHGIRAEL VQFVKGEKGETDIISDIFGIHTKKEGGSKHGHDAGLGDIAEILGTDTQSSLENTVRKKKG LQISEIAKEAEVERKAEAEKADMEDGEKQDIAKEVQSEQLEEGKMKKKKRRHGQKIEKPE AVMANFFKALEIYQIKMLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLDEVDEDS NLWNSFDEEDEEEGMVFFVLEESTGYMAPALRALAVIHTIISFVCVIGYYCLKVPLVVFK REKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLY GAERIAELLGLEKSALDFSPVEESEPEEASLVSWLSSIDTKYHVWKLGVVFTDNSFLYLA WYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTV VAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYR IVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPH GFETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDFFPAGDCFRKQYE DQLG NT seq 14595 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgttgccagtattcacaaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgcctgtgctttttggaaccaacatcagaagctaaatatgttcct ccggacctttgcatctgtaatttcgtcctcgaacagtccctatctgtcagagctcttcag gaaatgctggccaacacaggggatgatgctagtgaaggtgcagctcaagggggtggtcac agaaccctgctgtatggccatgctatactacttcgacattcgtttagtgaaatgtatttg acatgtttaacatcatcaagatcccagacggataaacttgcatttgatgtgggactacga gaaaatgcagcaggtgaggcatgctggtggacaatacaccctgcttctaaacaaaggtca gaaggagaaaaagttcgaattggtgatgatcttatcctggtcagtgtgtcctctgaaaga tacctgcatctctccatgtcaaatggaagtattcaggtggatgcctcctttatgcagacg ctatggaatgtacatcctacatgctcaggaagcaatattacagaaggatatcttcttggt gggcatgtagtacgtttgttccatggccatgatgagtgtttgacaattccatctacagat cagaatgattcacagcagaagaaagtactttatgaaaccggaggagctggtgttcgagca aggtctttgtggagagtagaaccccttcgaataagctggagtggaagtaacatcagatgg ggacagcctttccgtcttcgacatattacaacaggaaagtacttggctctgaatgaagat gaaggacttgcaatgttagacagagaaaagtcggacacaacatctactgccttttgtttt agagcatcaaaggagctaaaagaaaagcaggattctagtcttaaacgtgacattgatgga atgggagtcccagaaataaagtacggtgattcaatctgttttgtccaacatgtggccagt gccttatggttgacttacaaagcacaagatgctaaatcagcacgtttaggtcctgtgaaa agaaaggttatattacaccaagaaggccatatggatgatggtctaaccttacaaagatgt cagcatgaggaatcccaggctgctcgaatcattcgcaatactacaagcttattcagccag tttataagtggaaacaacaggacactatcaccctctgccctgcctattgaggagatggct cagactctgcaagacctgattacttacttccagcttcccgaagaagacctgggacatgaa gataagcaaagcaagcttcggtcactcaaaaacagacaaaatctattcaaggaagaggga atgctggcactagttttgaattgcattgatcgcttaaatgactacaacagcgcagctcat tttgcaggaattgcaagagaagaacatggtacagcacggaaagaaattttgaatctcctt tacaaattgttagctgctctcattcgtggcaacagaaacaattgtactcagttttccagt aacctggattggctaataagtaaattggacagattagaatcttcctcaggtattttggaa gtattgcactgcatcttgattgaaagcccagaagctttaaatattatagctgaggagcac atcaaatccattatttcattattggataaacacggtcgcaattacaaggttcttgatgtg ctttgctctctctgtgtctgtaatggagttgcagttcgtgccaatcaaaatttgatctgt gacaatctactgcctagaagagacttactcttgcaaacacgtttgattaatgatgtgaca agcataagaccaaacatatttttgggtgttgctgagggctctgcacaatacaagaagtgg tactttgagttaataattgatcaggttgatccattcttgacggcagaacccacccattta cgagttggatgggcctctacttcaggttatgccccctatcctggaggtggagaaggatgg ggaggcaatggtgttggtgatgacctgtactcttatggttttgatggccttcatctgtgg tctggtcgagttcccagagctgtggcatctgtcaatcagcatttattagcatctgatgat gtggttagctgctgcttggatttaggtgtacccagcatttcattccgcattaatggacaa cctgtacaaggaatgtttgagaacttcagtacagaagggtttttcttccctgttgtaagc ttatcagcaggtgtaaaagttcgtttcttactgggtggacgtcacggagagtttaaattt ctgcctcctgctggctatgctccctgttacgaagcattgcttccaaaagagaagatgaaa ctggaaccagtgaaggaatataagagagattctgatggagtgagggatttgctgggtaca acacaattcctctcccaagcttcctttatcccttgtccgatagacactagtcagattgct cttccttttcaccttgaaaagatcagggacaaactagctgaaaatatccatgaactgtgg ggaatgaataaaatagaactgggctggacatatggcaagatacgagatgataataaaagg catcatccttgtcttgtggaattctcaaaactacctgagacagagaagaattataatcta caaatgtcaactgaaaccctcaaaacccttttggcccttggatgtcacattgttcatgct catccagcagctgaggaagatcttaaaaaagtcaaacttcctaaaaattacatgatgtca aatggatataaacctgccccccttgatctttctgaagtgaaattgttaccttctcaagaa tttctagttgacaaactagcagaaaatgcacataatgtctgggcaaaagacagaataaag caaggatggacctatggcattcagcaggatcttaagaataaacgtaatcctcggctagta ccatatgcattattagatgaacgtaccaaaaaatcaaacagagatagcctccgtgaagct gttagaacatttgcaggctatggttatagtattgagccacctgaccaagagatagctgac caaacagtggaaaaagtcagcatcgacaagatacgatttttcagagtagaacggtcttat gcagtgaagtctggaaagtggtactttgaatttgaagctgtgacaggtggagatatgcgt gttggctgggccaggccaggctgtcgacctgacatagagttgggagctgatgaccaagca tttgtatttgaaggaagcaaaggccagcgttggcatcaaggcagtggattctttggacga agctggcaaccaggagatgtggttggttgtatgataaacttggatgacaaatcaattatc tttactctgaatggagagttgcttataaccagtaaaggttcagaacttgcatttgctgac tttggaatagaaagtggttttgttccaatttgtgcactgggtctagctcagattggtcgt atgaaccttggaatggatgccagtacattcaagtattatacaatgtgtggccttcaagaa ggttttgaaccttttgctgtcaacatgaaccgagatgttgctatgtggtttagtaaacgc ttaccaacatttgtcaatgtgccaaaaaatcatcctcacattgagatatggagaattgat ggaaccattgacagtccacctcggttaaaagttactcacaaaacatttggcacacagaac agcaattcagacatgatatattgtcgattgagtatgcccattgaattccgctcatcattc agctttggcatgggtgtggaaaatgcctcatctgatgttttccaaaaacgaaagcacagc caagaaattgctgctccttgtactacatatttttattcactacggatatttgctggccaa gacccatcctctgtctgggttggctgggtaacaccagactatcatttttacagtgagaat tttgacctaaataaaaattgtacagtgacagttactttaggtgatgagagaggcagggtt catgaaagtgtgaagcgcagcaattgctatatggtttggggaggagatgtaattgcgaat tcccagagatcaggtcgcagtaatgttgatttagaaattggatgctttgttgacctggct actggaatgttgtcattcacggccaatggaaaagagcttggcagttgttatcaggttgaa ccaaacacaaagctttttccagcaacttttgtacagcctacgagcactaacttggttcaa tttgaacttggtaaattaaagaataccatgcctttatcagcagcaattttcaaaagtgaa gaaagaaatcctgttcctcagtgtccccctcgccttgatgtgcaaacaattacacctgtt ttatggagcaggatgccaaacagctttctaaaagtagaaactgagcgtgtcagtgaacgt catggctgggttgtgcagtgtttggaacctctgcagatgatggcacttcatatcccagaa gaaaacagatgcgttgatattttggaactatgtgaacaagaagatttgatgaagtttcac taccacactttaaaactctatagctcagttagtgctctaggtaacactagagttgcttat gcactttgtagccatgtggacatatctcagctattttatacaatagataatcaatattta cctggacttctacgttccggattctatgacttgctcattagtattcatttggagcacgcc aagcaagccaagctcatgatgaacaatgaatttattattccagttacagatgaaactcga actattaaattatatcctgatgaaacaaagaagcatggtttacctggagtagggcttagt acttgtctgaaaccaggctttaatttttctactccatgctttattgtgaccagtgaagaa catcagacatccagcccagagataccccttgatacacttaaatccaaggccataagtatg ctaacagaggcagtacagtgtagtggtactcatatacgagaccctgttggaggacaggtt gcattccagtttgttccagttcttaaactgatagcaacattgctcataatgggggttttt gatgatgatgatgtgaagcaggtgttactcctcattgatcccaatgtgtttggagatcac aaggaagaaacagaagagaggacagagaaggaagaagttacacaagttgaagaaaaagct gtagaagctggcgagaaagcagtaaaagaaacaaaagctcctgcaaagggcttattacag acaagattaccagaatctgttaagcttcagatgtgtcatttactcaattatttctgtgac tgtgagctacaacacagagtggaagcaattgtatcatttgcagactgttatgtatcaaaa ctgcaatataatcagaaatacaggtacaatgaactcatgcaagccttgaacatgtctgct gctttgactgccaaaaagactaaagagtttcggtctcctcctcaagaacagattaatatg ttgctgaattttcaactgggagaggattgtccttgtccagaggagattcgggatgagtta tatgaatttcatgatgatcttctaattcactgtggtattccactggaagaggaggaagag gaagaggaagattcctccttgactggcaaactccgttcattaatgtacaaaatcaaaggt ccaccaaaagcagaaaaagtagaaccaaaggaggaagaagagaaatctcctactacgctg aaagaactcatatcccagactatggtgcgctggtcccaggaagatcagattcaagatcca gaattagttcggattatgtacaccctccttcgtaggcagtatgacagcattggtgagcta ctgcaagctctgaggaaagcgtacactattagtgctgcctctgtgaaggataccattaat ctgcttgcagcactgggccagattcgctcacttctcagtgtcaggatgggaaaagaggag gaattgctaatgattaatggattaggggatataatgaacaacaaggtgttttatcagcat cctaacttaatgagagtcttgggcatgcatgagactgttatggatgtgatggtgaatgtg cttggaggagataaatctcagatcatttttcctaagatggtggcaagctgttgtcgattc ctgtgctacttctgtcgaattagtcgtcaaaaccaaaaggccatgtttgaacatcttagt tacttgctggaaaacagcagcgttggtctggcgtttccttcaatgagaggttcaacacca ctagatgttgcagcagcctctgtaatggacaacaatgagcttgcactagcattggaggag ccagatctcgataaggttgttacctacctggcgggttgtggcctgcagagttgtccagta ttgctggctaaaggatatccagacattggatggaatccaatagagggtgaacgttacctg tctttcttaagatttgcagtgtttgttaacagtgaaagtgttgaggaaaatgcaagtgtt gttgtcaagctccttattcgacggccagagtgctttggaccagaccttaggggagaagga ggaaatggtttgctggcagctatgcaggaagctatcaggatctcagagaatcctactcgt gaccttccctcccaggcatataaaagagaaggtgatgatggtgaggaggaagagattgtg cacatgggcaatgcaatcatgtcattttactcagctctcatagatttacttggacgctgt gcaccagaaatgcatcttattcaaagtggaaaaggggaagctattcgaatcaggtcaatc cttcgatctctagtgccaactgaagatttggttgggattataagtataccactaaagctg tcaacagttaacaaagatggcacagtaaacgagccagacatgtctgcaaatttctgtcct gatcataaagcacccatggtactcttcttggaccgtgtctatggtattaaggaccaaagc ttcctccttcacctactagaagttggatttttaccagatttaagagcctctgcctctttg gatacagtttctctaagtaccacagaggcagctctcgcactaaatagatatatttgctca gctgtgtttccattactcaaaagatgtgctcccctcttttctggaacagagcatcacgcc tctctggttgactccatgcttcacacaatatatagattatcgaagggacgttcccttaca aaagcacaaagagacaccattgaagaatgcctgcttgctatttgccaccacttacgtccc tctatgctacaacagctgttgagaaggctagtttttgatgtgcccctacttaatgaatac tgtaaaatgcctctcaagcttctgacaaatcactatgagcagtgctggaaatattattgt ctgccttcaggaatgggaagctatggaattgcagcagaagaagaattacatttaactgaa aaacttttctggggaatatttgattccttgtctcataagaagtatgatccagagctcttt cgaatggctttgccttgtctaagtgctatagctggtgccttgccccctgattatttagat acacgaattaggtcaactttggaaaagcagacttcagtggatccagaaggaaattttgat cccaaacctgtcagcacagcaaaccttgtacttcctgaaaagttggagtatattgtcagc aagtatgctgaacattcccatgataaatgggcctttgataagactaatagtggatggaaa tatggtatttcactggatgaaaatatgaagactcacccattaataagacctttcaaaact ttaactgaaaaggaaaaggaaatttatcgttggcctgccagagaatcactgaaaaccatg ttggccatgggatggagcctagaaagggccaaggaaggaggagaagcaataatacatcag cgtgaaaatgaaaagctccgcagcatatctcagtctagccagggaaatgggtatagcccg gcaccacttgatctctctaatgtagtgctttctagggagcttcagggaatggttgaggta atggcagaaaactaccataatatatgggccaaaaagaagaagatggagttggaaagcaaa ggtggaggtagccatcctttattggtaccttacgacacattgacagccaaggagaaatca cgggaccgtgaaaaggcacaagagctgtttaaattccttcaagtcaatggtataatcata tctcggggtctgaatgacatggacttagatgcttcatccatggaaaagaggtttgccttt aagtttctgaagaaaattttaaaatacgttgattctgctcaagagtttattgcacatttg gaggccattgtaaccagtggaaaaactgaaaaatcgccacatgaccaagaaataaaattc tttgccaaagttcttttaccattagttgatcagtactttacaaatcactgcctctacttc ctgtcttctccaacaaaaacactcagtagcagtggatatgcatcaaataaggaaaaggaa atggtagcaagcctgttctgcaaactagctgctcttgttagacataggatctcacttttt ggtagcgattctgctacaatggtgaactgcctgcatatcttagctcagtctcttgacaca cgaactgttatgaaatcaggatctgagcttgttaaagctggattgcgtgccttttttgaa aatgcagctgaagacctggaaaaaacttcagaaaatcttaaacttggaaaatttacccat tcacgaacacaaatcaagggtgtttcacagaatatcaattatactacagtagcattgtta ccgatcttgacatcaatttttgaacatatttcacaacatcactttggaattgatttactt ttgggtgatgtacaagtttcatgttacagaattctttgtagcctctattcccttgggact gggaagaacatctatgttgaaaggcagcgtcccgcacttggtgagtgcttagcatctctt gcagcagccattccagtagcattccttgaaccttctctcaaccattacaacccattgtct gtcttcaacacaaaaagtgcaagagaaagagcaattttaggtatgcctgatacagtagaa gagatgtgtccagagatccctcagttggatggactaataaaggaaattaatgatttagca gagtctggagcaaggtatactgaaatgcctcatgtaattgaggttatcttacccatgctg tgcaactatttgtcctactggtgggaaagagggtctgagagtcttcctcaaagtgctggg ccttgctgtacaatgataacatctgagcatctgagcatcattcttggaaacattctgaaa atcattaacaacaacctgggaatagatgaagcatcttggatgaaaagaattgcagtttat gctcaacccatcatcagcaaagccaggcctgatctgctcaaaactcactttattccaaca ctggagaaattgaagaagaaagctataaagattgtgatggaagaggagcaactgagagca gatagtaaaactgacacccaagaagctgagctactcattctcgatgagtttgctgttctt tgtagagacctttacgccttctatccaatgctgatacgttatgtagacaacaacagagcc aactggctaaagaaaccagatgcagattccgatgaactctttcgaatggtagctgaagtt tttatcctgtggtgtaaatcacataatttcaaaagagaagaacaaaattttgtgattcag aatgaaatcaacaatttggcatttttaacaggagacaccaaaagcaagatgtctaaatct ggaggacaagatcaagagagaaagaaatcaaaacgtagaggggatttgtactccatacaa acatccttgattgtagctgcacttaaaaagatgcttcctattggtttgaatatgtgtact cctggagatcaagagctcatctctttggctaagactagatacagccatagggacactgat gatgaagtcaaagaacatttacgtaacaacttacatttacaggaaaagtctgatgatcca gctgtgaaatggcagttaaatctgtacaaagacattttgaagagtgatgaacctactgac cctgagagaaatgtagaacgtgtgcagaggatatcagctgctctgtatcatctggaacag gttgaacaaccactgagatcaaagaaagctgtttggcacaaactcctgtcaaaacaacgc aaaagggctgttgttgcatgtttcagaatggcaccattatacaacctaccaaggcaccgt tctattaacctcttcctccatggctatcagaactattggatagaaacagaggaatattca tttgaggagaaactagttcaggatttggctacacctccaaaaaaagaggaagaggaagag gaagagactgagaaaaaacagcctgatccacttcatcagatcatcctctattttagtcgc agtgctctcacagagagaagcaaactagaagatgatcctttatatattgcctattccgcc atgatggcaaagagctgtcaggaggaggaagaagaggaagaagaagaaaaagaaaagaca tttgaggagaaagaaatggaaaaacagagaactctctatcagcaagctcgcttgcatgat cgtggagctgctgagatggtccttcagatgattagtgcaagcaaaggtcatccaggaccc atggttgttgaaacactaaaacttggtattgctattctaaatggtgggaataccatagtt caacagaaaatgctagactacctgaaggagaaaaaggatgctggattttttcaaagtctc tctggcttgatgcagtcctgcagtgttcttgacttgaatgcatttgagagacaaaataaa gcagaaggcctggggatggttactgaagaaggaactctcatcgttcgtgagcgtggtgaa aaagtgttgcaacacgatgaatttactcgagatctatttagatttttacaactgctctgt gaagggcataacaatgattttcaaaattacctacgtactcagatgggcaacaccacaaca gtgaatattatcattagtacagttgactatctcttgcgtcttcaggaatcaatcagtgac ttctattggtactattcaggaaaggatatcattgatgaatcaggacaacgtaacttctct aaagctttggctgtcaccaaacaaatattcaattcccttacagaatacatccagggccct tgcataggtaatcaacagagtctggctcatagtaggctgtgggatgcagttgttggcttt cttcatgtctttgccaatatgcagatgaaactttcacaggactctgctcagattgaattg cttaaagaactgctagatctgctaaaggatatggtagtgatgctcttgtcactgcttgaa ggtaacgttgtaaatggaactattggaaaacaaatggtagacacgcttgtagaatcatct agcaatgtagaaatgattttgaagttctttgacatgttcctcaagttaaaagatctgact aactcagatgctttcaaagagcatgaccctgacggtaaaggcatcatttcaaagaaggaa ttccagaaatcaatggaggctcaaaaacaatacatacagtcagagattgaattcctacta tcctgtgcagaagctgatgaaaatgatatgtttaactatgttgattttgtggaaagattc catgaaccagccaaagacattggatttaatgtagcagtattgctaacaaacctttcggag cacatgcctaatgattcacgccttcagagcttacttgaacctgcagaaagtgttcttaat tactttgaaccataccttggccgtattgaaataatgggtggagccaagaaaatagaaaga gtttactttgaaatcagtgaatccagtagaatgcagtgggagaagccacaggtgaaggaa tccaaaaggcagttcatatttgatgttgtaaatgaaggtggagagcaagaaaaaatggaa ctctttgtgaatttctgtgaagacacaatctttgaaatgcagttagcatcccagatctct gaaacggattcatctgagaggcctgaggaagaggaagaggcagagccttgttatgtagtg gatattggagatgatgaagaagaagaaaagtccctggaatctgcttcagcttttgcaatg gcttgtgttgcagtgaagaagaatgttgccaacttttttaaaatggccactgtaaagaac ctaagaaaacaatacaggaaagttagaaagatgacagtaaaagagatggtgaaagtgttt ttctcctttttctggatcctatttgtagggatgttccaactgttctttactatagtgtgg ggaattttccagattctttggagcactgtatttgggggtggcctggttgaaggagccaag aacattaaagttactaaaatattaggggacatgcctgacccaacacagtttggaatccat gatgatgttatggaagcagaaaaagctgaaggcgctgaacatggcatcagagctgaactt gtgcagtttgtgaagggtgaaaagggagaaactgacatcatctcagacatttttggcatt catacaaagaaagaaggtggctcaaaacatggtcatgatgctggacttggagatattgca gaaatccttggtactgatacccagtcgtctttggaaaacacagttcgtaagaaaaaagga ttacagatatctgaaattgcaaaagaagctgaagtggaaagaaaagcagaagctgagaag gctgacatggaagatggtgagaaacaagacatagcaaaggaagtacaatctgagcagcta gaagagggaaaaatgaagaaaaagaagcgaaggcatggacaaaaaattgagaaaccagag gctgtgatggctaacttcttcaaagctttggaaatttatcaaataaaaatgcttcactac ttggcaagaaatttttataacttaaggtttcttgctctatttgttgcatttgccatcaac tttattcttctattttacaaggtgacagaagagccacttgatgaagtagacgaagactct aatctctggaactcttttgatgaagaggacgaggaggagggcatggtgttttttgtttta gaagaaagtacaggttacatggcacctgctctcagggcattggcagttattcatactatc atctcctttgtctgtgtgattggatactattgtttaaaggtccctctggttgtattcaag agagaaaaggaggtagctagaaagctggaatttgatggactgtacataactgaacagcca tctgaagatgatattaaaggacaatgggatcgcctggttataaatactccgtcctttcct aacaattactgggacaaatttgtaaaacggaaggttattaacaagtacggagacttatat ggagcagagcgcatagcagaacttttgggtttggaaaaaagtgctcttgattttagtcca gtggaagagagcgaaccagaagaggcatctcttgtatcatggttaagctccattgataca aagtatcacgtttggaagcttggagttgttttcactgataattcgtttttgtacttagct tggtacacaactatgtctatccttgggcactacaacaacttcttctttgctgctcacctg ctggatattgctatgggtttcaagacactgcgaaccattttgtcttcagtcactcacaat ggcaaacagcttgtgcttactgtaggactcctcgctgtagtagtctatctttacactgtt gtggcgttcaacttcttccgcaaattctacaacaaaagtgaagatgaagatgaaccagac atgaaatgtgatgacatgatgacgtgttacctattccacatgtatgtgggggtaagagct ggtggtggcattggagatgaaattgaggatcctgctggagacccttacgaaatgtatcga attgtctttgacatcacgtttttcttctttgtcattgttatcctactggccattattcaa ggtctgattattgatgcttttggtgaattaagagaccagcaagaacaagtgagagaagat atggagaccaaatgttttatttgtggaattggcaatgactattttgacacaaccccacat ggctttgaaacgcatactttgcaagaacacaacttggcaaactatctgttctttttaatg tatctcattaacaaggatgaaactgagcatactggccaggagtcatttgtgtggaagatg taccaagaaaggtgttgggattttttcccagcaggcgactgcttccggaaacagtatgag gatcagcttggctaa

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