KEGG   Hippoglossus hippoglossus (Atlantic halibut): 117758003
Entry
117758003         CDS       T07778                                 
Symbol
cad
Name
(RefSeq) CAD protein
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
hhip  Hippoglossus hippoglossus (Atlantic halibut)
Pathway
hhip00220  Arginine biosynthesis
hhip00240  Pyrimidine metabolism
hhip00250  Alanine, aspartate and glutamate metabolism
hhip01100  Metabolic pathways
hhip01240  Biosynthesis of cofactors
Module
hhip_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:hhip00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    117758003 (cad)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    117758003 (cad)
   00220 Arginine biosynthesis
    117758003 (cad)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hhip01002]
    117758003 (cad)
Enzymes [BR:hhip01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     117758003 (cad)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     117758003 (cad)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     117758003 (cad)
Peptidases and inhibitors [BR:hhip01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   117758003 (cad)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   117758003 (cad)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 MGS ATP-grasp Dala_Dala_lig_C DHOase ATPgrasp_Ter Amidohydro_1 ATP-grasp_3 Peptidase_C26 GARS_A GSH-S_ATP
Other DBs
NCBI-GeneID: 117758003
NCBI-ProteinID: XP_034435173
LinkDB
Position
24:2124135..2140373
AA seq 2232 aa
MATLILEDGATFRGRPFGAAVSVSGEVVFQTGMVGYPEALTDPSYHCQLLTLTYPMIGNY
GVPPNEDGDFGLSKWFESSKIHAAALIIGELSDSPSHWSSVKSLDQWLKEHGIPGIQGID
TRCLTKKIREKGTMLGKLVLDGTPEDSIPLDNPDHRNLVQEVSMKEPRVFNPSGSPRITV
VDCGIKYNQIRCLAERGARVTVVPWDHPLDSAEFDGLFVSNGPGDPQLCQATINNLRKVV
CVDRPKPVFGICLGHQLLSLVIGAKTYKMKYGNRGHNQPCIHHGTDRCFITSQNHGFAVD
PDTLPADWDVLFTNANDHTNEGIVHNVHPLFSVQFHPEHMAGPTDLVGLFDVFLDTVKDH
KDGSASKTVKQQLVDHLTFPGSPKPEDVTRPRKVLILGSGGLSIGQAGEFDYSGSQAIKA
LKEENIQTVLINPNIATVQTSKGLADKVYFLPITAEYVTQVIKNERPDGVLLTFGGQTAL
NCGVELTKLGVLEKYNVKVLGTPVSSIEMTEDRKVFVEKMEEIGEHVAPSEAALSVEQAL
AAAERLGYPVLVRAAFALGGLGSGFANNKEELTSLVTSAFAHTVQVLVDKSLKGWKEIEY
EVVRDAYDNCVTVCNMENVDPLGIHTGESIVVAPSQTLNDHEYNMLRNTAIKVIRHLGIV
GECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLSLGIPLPQLKNSV
TNSTTANFEPSLDYCVVKVPRWDLSKFLRVSTTIGSSMKSVGEVMAIGRSFEEAFQKALR
MVDENCVGFDHTIKPVSETELLIPTDKRIFVLAAAFKDGYTVDQLHELTKIDRWFLYKMK
NISDHERLLETYNQNESTMPPDAMLKAKQLGFSDKQIGLAVQSTELAVRKLRHDWSIIPV
VKQIDTVAAEWPAFTNYLYLTYHGTENDLTFEDQHVMVIGSGVYRIGSSVEFDWCAVGCI
TELRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYERENPEGVILSMGGQL
PNNIAMSLHRQLCRILGTSPEFIDSAENRFKFSRMLDTIGISQPQWKELSDTESAMTFCE
KVGYPCLVRPSYVLSGAAMNVAYGDTDLEKYLSNAMAVSKEHPVVISKFIQEAKEIDVDA
VACDGVVMAIAVSEHVENAGVHSGDATLVTPPQDINQKTMERIKIIVHAIGQELQVTGPF
NLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRLIMGEDMEPVGLMRGKGIV
GVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNILLSI
GSYKNKSELLPTVQALESLGYDLYASLGTADFYTEHGVKVMAVDWPFEEEESDCPTKEKQ
RSIMNYLEENHFDLVINLSMRNSGGRRLSSFVTKGYRTRRMAIDYSVPLIIDIKCTKLFV
QALHQIGPTPPVKTHIDSMASQTLVRLPGLIDVHVHLREPGATHKEDFSSGTAAALAGGV
TMVCAMPNTSPAVTDASTLALVQKLAKAGCRCDYALYLGAASDNAAVLPSIASQAVGLKM
YLNDTYSTLKMDNVSLWMEHFEKWPKQMPIVAHAEKQTVAAILMVAQLYQRPVHICHIAK
KEEILIIRAAKQKGIQVTCEVAPHHLFLCEDNVPDIGDGPAQVRPMLGTREDMEALWENL
DIIDCFATDHAPHSVEEKNSERPPPGYPGLETMLPLLLTAVSDGRLTLDDIIRRLYDNPR
KIFNLPVQENTYVEVDLEHEWVIPPSMQFTKSKWTPFQGLKVKGKVRRVVLRGEVAYIDG
QVLVPPGYGEDVKTWPTAPIIPPEPVKEAPMTPEHTRPTPPREGPIRTRAASPRRGAGDG
RYLLPPRTHRSSDPGLPLEMLMMLPPAVVADGYGHPPPLSRLLSPQPGPGQILAGPASHF
QTSPLLHPLIGQHILSVRQFSKEQISHLFNVAHTLRMMVQKERSLEILKGKVMASMFYEV
STRTSSSFSAAMQRLGGSVVHFSESTSSTQKGESLSDSVQTMSCYADVLVLRHPTPGAVE
SASRHCRKPVINAGDGVGEHPTQALLDVFTIREELGTVNGMTITMVGDLKHGRTVHSLAK
LLTQYRITLRYVAPKNLHMPAEIISYVASKGIKQEEFESIEEALPETDVLYMTRIQKERF
ASEEEYKACFGQFILTPHIMTVAKRKMVVMHPLPRVNEISAEVDTDPRAAYFRQAENGMY
IRMALLATVLSR
NT seq 6699 nt   +upstreamnt  +downstreamnt
atggccacgctgatcctggaggacggagccacgttcaggggccgcccgttcggagccgcc
gtgtccgtgtccggggaagttgtgtttcagacgggtatggtgggctaccccgaggcgctg
actgacccatcctaccactgccagctgctgaccctcacctaccccatgatcggcaactac
ggggtgccgcccaacgaggatggagatttcggactcagcaagtggttcgagtcgtctaag
atccacgctgcagctctgattatcggagagctgtcggacagtcccagtcactggagctca
gtcaagtcactggaccagtggctcaaggagcatggcatccccggaatacaagggatcgac
acccgctgcctgaccaaaaagatccgagagaagggcaccatgctggggaagctggtgctg
gacgggactccagaggacagtattcccctggataaccccgaccacaggaacctggtccag
gaggtgtccatgaaggagccccgagtatttaaccccagtggcagtccgcgaatcacggtg
gtggactgtggcatcaagtacaaccagatccgctgcctggctgagagaggggcccgtgtc
actgtggtgccctgggaccacccgttggacagcgcagaatttgatggtttgttcgtcagt
aacggtcccggggatcctcagctctgtcaggccacgatcaacaacctgaggaaggtcgtg
tgcgtcgatcgccccaagccagtcttcgggatctgtctcggacaccagctgctctctttg
gtcatcggagcgaagacgtacaagatgaagtacggtaaccgaggccacaaccagccctgc
atccaccacgggacagatcgctgcttcatcaccagtcagaatcacggcttcgctgtcgac
cccgacactctccccgcggactgggacgtcctcttcaccaacgccaacgaccacaccaac
gagggcatcgtacacaacgtgcatcccctgttcagtgttcagttccatccggagcacatg
gctggtccgacggatctggtcggcttgttcgatgtcttcctcgacactgtgaaggaccac
aaagacggcagcgcctcaaaaacagtcaagcagcagctggtggatcacctgaccttccct
ggttccccgaagccggaggatgtgacccgacccaggaaggtcctcatcctgggctctggt
ggtctgtccatcggccaggctggagagtttgactactccggctcccaggctatcaaggct
ctgaaggaagagaacatccagactgtgctgatcaaccccaacatcgccactgtccagacg
tccaaaggcctggcggacaaagtctacttcctgcccatcactgcagagtacgtcactcag
gtgataaaaaatgaacgccctgacggtgtcctgttgaccttcggcggtcagacggcgctg
aactgtggcgtggagctgaccaagctcggtgtcctggagaagtataatgttaaagttctg
ggaactccggtgtcctccatcgagatgactgaggacaggaaggtctttgtggagaagatg
gaagagatcggcgaacatgtcgcccccagtgaagcggcgctgtctgtggagcaggcgctg
gctgctgcggaacgcctcggctaccccgtcctggttcgtgcagcgttcgccctcggaggt
ctgggctcgggcttcgccaacaacaaggaggagctgacttctctggtgacgtcggccttc
gcacacaccgtccaggtactggtggacaagtccctgaaaggctggaaggagatcgagtac
gaggtggtccgagacgcctacgataactgtgtcaccgtgtgtaatatggagaacgttgat
cctctgggcatccacactggggagtccattgtggtggcgccgagtcaaacgctgaacgac
cacgagtacaacatgctgaggaacaccgccatcaaagtcatcaggcacctcgggatcgtg
ggagagtgcaacatccagtacgctctcaaccctgaatcagaacagtattacatcatcgag
gtgaatgctcgtctgtcccggagttcggccctggccagtaaagccactggttaccctctg
gcctacgtagcggccaaactcagcctggggatcccgctgccgcagctcaaaaattctgtc
accaactccacgacagcaaactttgaacccagtttggattactgtgtggtgaaggtgcct
cgctgggacctcagcaagttcctcagggtttccaccacgatcggcagctccatgaagagt
gttggggaggtgatggctattggccgcagcttcgaggaggccttccagaaagctctgagg
atggtggacgagaactgtgtcggcttcgaccacacgatcaaacctgtctctgaaacggag
ctgctgattcccacagacaagcgcatctttgtgctggcggcggcgtttaaagacggctac
acggtggaccagctgcacgagctcacaaagatcgaccgctggttcctgtacaagatgaag
aacatctccgaccacgagcggctgctggagacgtacaaccagaacgagagcaccatgcct
ccagatgcgatgctgaaggccaagcagctgggattctccgacaagcagatcggactggct
gtacagagcactgagcttgcggtgaggaagctgcgccacgattggtccatcatccccgtg
gtgaagcagatcgacacggtggccgccgagtggccggctttcacaaactacctgtacctg
acctaccatggtacggagaacgacctgaccttcgaggaccagcacgtcatggtgatcggc
tccggcgtgtatcgcatcggcagcagcgtggagttcgattggtgcgcagtgggctgcatc
accgagctcaggaagatgggttataagaccatcatggtgaactacaaccctgagaccgtc
agcacagactatgacatgtgtgaccgcctctactttgatgaaatctcctttgaggtggtg
atggacatctatgagagggaaaacccagagggggtgatcctgtcgatgggaggccagctg
cccaacaacatcgccatgtcgctgcaccgtcagctgtgccgcatcttggggacgtcgccc
gagttcatcgacagcgccgagaaccggttcaagttctccagaatgctggacaccatcggc
atcagccagccacagtggaaggagctgtccgacactgagtctgctatgacattttgtgag
aaggtgggatatccctgccttgttcgtccttcctacgttctgagcggagcagccatgaat
gtggcctacggtgacaccgaccttgagaaatacctgagtaacgctatggctgtgtccaag
gagcaccctgtcgtcatctccaaattcatacaggaagctaaggagatagatgtggacgcg
gtagcgtgtgacggggtcgtgatggccatcgcggtgtctgaacatgtggagaacgccggc
gttcactccggtgatgccacactggtgacgccgcctcaggacatcaaccagaagaccatg
gaaaggatcaagatcatcgttcacgccatcggccaggagctgcaggtcaccggacccttc
aatctgcagctcatcgccaaggatgaccagctgaaggtgatcgagtgcaacgtccgggtg
tcccgctccttcccgttcgtatccaagaccctgggcgtggacctcgttgccctggcaaca
cgactcataatgggggaggacatggagcccgtgggcctgatgagagggaaggggatcgta
ggagtgaaggttcctcagttttcgttctctcgtctggccggagcggacgtggtgctcggg
gtggagatgaccagcaccggagaggtcgcctgttttggggagaaccgatacgaggcgtac
ctcaaagccatgctctccacgggcttcaagatccccaagaagaacatcctgctctccatc
ggcagctataagaacaagagcgagctgctgcccaccgtgcaggcgctggagtctctgggt
tacgacctgtacgccagtctgggcaccgcggatttctacaccgagcacggagtcaaggtg
atggcggtagactggccgttcgaggaggaagagagcgattgtcccactaaagagaagcag
cgcagcatcatgaactacctggaggaaaaccacttcgacctggtcatcaacctctccatg
aggaacagcgggggtcgtcgactctcctccttcgtcaccaaaggctacaggacgagacgc
atggccatcgactactccgtcccgctcatcatcgacattaagtgcacgaagctgtttgtt
caggctcttcatcagatcggcccaactccaccagtgaagactcacatcgacagcatggct
tcccagacgctggtccggctccctggtctgatcgacgtgcacgttcacctgcgcgagcct
ggtgccacacacaaggaggacttctcctccggtacggcagccgctctggcaggaggcgtg
accatggtgtgtgcgatgcccaacacttccccggccgtcacggacgccagcactctggct
ctggtacagaagcttgctaaagcgggctgcaggtgtgactacgccctgtatctgggcgct
gcttcagacaacgctgccgtgctgccgtctatcgccagccaggcggtcggtctgaagatg
tacctgaacgacacgtactccaccctcaagatggacaacgtgtctctctggatggagcac
tttgagaagtggcccaagcagatgcccatcgtggctcacgctgagaagcagacggttgct
gcgatcctgatggtggctcagctctaccagcgcccggtccacatctgccacatcgccaag
aaggaggagatcctgatcatccgcgcggccaagcagaagggcatccaggtcacgtgtgag
gtggcgcctcatcacctcttcctgtgtgaggacaatgtgccggacatcggtgatggtcca
gcgcaggtccgacccatgctgggaacccgggaggacatggaagcgctctgggaaaacctg
gacatcatcgactgcttcgccacagaccacgcgcctcactctgttgaggagaagaacagc
gagcgtcctcctcctggttaccccggcctggagaccatgctgccgctgctgctgaccgcg
gtcagcgatggacgtctgactctggacgatattatcagacgtctctatgacaacccacgc
aagatctttaacctgcctgtccaagaaaacacctacgtagaggtggacttggagcacgag
tgggtgattcctccgtccatgcagttcaccaagtccaagtggacgccattccaaggtctg
aaggtgaagggtaaagtccgccgtgtggttctgagaggagaggtggcctacatcgacggg
caggtgttggtacctccaggttatggtgaagatgtgaagacgtggcccacggcccccatc
atccctcccgagccagttaaagaagctcctatgactccagagcacactcgtcccactcct
ccccgtgaaggcccgattcgaacccgagccgcgagcccccggcgcggcgcaggggacggc
cgctacctgctgccaccgcgcacccaccgctcatctgatcccggactaccactggagatg
ctgatgatgcttcctccagccgttgtggcggacggttacggccaccccccccctctgtcc
cggctgctctcccctcagccgggtccgggtcagatactcgctggaccggcgtcccacttc
cagacgtctccgctcctgcacccgctgatcggccagcacatcctgtctgtgcggcagttc
agcaaagaacagatctcacaccttttcaacgtcgcccacactttgcgtatgatggttcag
aaggagcgaagcctggagatcctgaagggtaaagtgatggcgtccatgttctacgaggtc
agcactcgcaccagcagctccttctccgcggccatgcagcgtctcggcggctccgtcgtc
cacttcagtgaatccacctcgtccacgcagaaaggagaatctctgtccgactcggttcag
accatgagctgctacgctgacgttctggtgctccgacacccgacgcccggagctgtggag
agtgcgtcccgtcactgccgtaaaccagtgatcaacgctggagacggcgtcggggagcat
cccacccaggccctgctggacgtcttcaccatcagagaggagctggggacagtcaacggc
atgacgataactatggtcggtgatctgaaacatggccgcacagttcattccctcgccaaa
ctgctgacccagtaccgcatcactctgcgctatgtggcgcccaagaacctccacatgccg
gcagagatcatcagctacgtggcctcaaagggcatcaaacaggaggagtttgagagcatt
gaagaagctctgcctgagaccgacgtcctctacatgacgaggatccagaaggagaggttc
gcctccgaggaggaatacaaggcctgtttcggtcagttcatcctcactcctcacatcatg
actgtggccaagaggaagatggtggtgatgcatccgctgcccagagtcaatgaaatcagt
gccgaagtggacacggacccgagagcagcatatttccgtcaggcggagaacggcatgtac
atccgaatggccctgctggccaccgtactgagcagatag

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