Hyaena hyaena (striped hyena): 120228884
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Entry
120228884 CDS
T07257
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv04010
MAPK signaling pathway
hhv04020
Calcium signaling pathway
hhv04022
cGMP-PKG signaling pathway
hhv04024
cAMP signaling pathway
hhv04260
Cardiac muscle contraction
hhv04261
Adrenergic signaling in cardiomyocytes
hhv04270
Vascular smooth muscle contraction
hhv04723
Retrograde endocannabinoid signaling
hhv04725
Cholinergic synapse
hhv04726
Serotonergic synapse
hhv04727
GABAergic synapse
hhv04911
Insulin secretion
hhv04912
GnRH signaling pathway
hhv04921
Oxytocin signaling pathway
hhv04924
Renin secretion
hhv04925
Aldosterone synthesis and secretion
hhv04927
Cortisol synthesis and secretion
hhv04929
GnRH secretion
hhv04934
Cushing syndrome
hhv04935
Growth hormone synthesis, secretion and action
hhv05010
Alzheimer disease
hhv05020
Prion disease
hhv05022
Pathways of neurodegeneration - multiple diseases
hhv05207
Chemical carcinogenesis - receptor activation
hhv05410
Hypertrophic cardiomyopathy
hhv05412
Arrhythmogenic right ventricular cardiomyopathy
hhv05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
120228884 (CACNA1S)
04020 Calcium signaling pathway
120228884 (CACNA1S)
04024 cAMP signaling pathway
120228884 (CACNA1S)
04022 cGMP-PKG signaling pathway
120228884 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
120228884 (CACNA1S)
04929 GnRH secretion
120228884 (CACNA1S)
04912 GnRH signaling pathway
120228884 (CACNA1S)
04921 Oxytocin signaling pathway
120228884 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
120228884 (CACNA1S)
04924 Renin secretion
120228884 (CACNA1S)
04925 Aldosterone synthesis and secretion
120228884 (CACNA1S)
04927 Cortisol synthesis and secretion
120228884 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
120228884 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
120228884 (CACNA1S)
04270 Vascular smooth muscle contraction
120228884 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
120228884 (CACNA1S)
04725 Cholinergic synapse
120228884 (CACNA1S)
04726 Serotonergic synapse
120228884 (CACNA1S)
04723 Retrograde endocannabinoid signaling
120228884 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
120228884 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
120228884 (CACNA1S)
05020 Prion disease
120228884 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
120228884 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
120228884 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
120228884 (CACNA1S)
05414 Dilated cardiomyopathy
120228884 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
120228884 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hhv04040
]
120228884 (CACNA1S)
Ion channels [BR:
hhv04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
120228884 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Lambda_Kil
Motif
Other DBs
NCBI-GeneID:
120228884
NCBI-ProteinID:
XP_039083443
LinkDB
All DBs
Position
Unknown
AA seq
1871 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPGPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIIFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSRVFYWLVILIVALNTLSIASEHHNQPLWLTHLQDIANRVLLALFTIEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVFCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDAYKEDTGPVYNYRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDFAPGEEYTCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTIQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFMERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPRTNPLAHANTNNANANVAYDNSNHSNSQV
FSSFRYEREFPGETEPPAARGGVFGQPQRVLGAHSKSCVEKLKGQLTQIEGPRARASPTP
CQHARAEPPLPEERRDPTPGPEDAPHSGRTKENSSRCQTPATARLIQEALVRGGLDTLAA
DADFVMVTGQALADACQMEPEDVEVAATELLKSQGSPEGMASAQGRLSLRSSLGSLDQHQ
GSQETLLPPRM
NT seq
5616 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggatgagggcctgaggaagaaacagcccaagaagcccggt
cctgagattctgccaaggccaccccgggccctgttctgcttgaccctgcagaaccccctg
aggaaggcctgcatcaacatcgtagaatggaaacccttcgagacaatcatcttgctcacc
atctttgccaactgcgtggccctggccgtgtacctgcccatgccagaagatgacaacaac
actctgaaccttggtctggagaaactggagtatttcttcctcatcatcttctcaattgaa
gccgccatgaagatcattgcctatggcttcctgttccaccaagatgcctacctgcgcagt
ggctggaatgtgctagacttcatcatcgttttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacacagccccgatgagcagcaaaggcgctggcctggac
gtcaaggccctgagagccttccgtgtgctcagacccctccggctcgtgtcgggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgcttcccctgttccacatcgcc
ctgctcgtcctctttatggtcatcatctatgccatcatcgggctggagctcttcaagggc
aaaatgcacaagacctgctacttcattgggacagatatcgtggccacagtagagaacgag
aagccctcaccctgcgccaggacgggctcgggacgcccgtgtaccatcaatggcagcgag
tgccggggcggctggccaggacccaaccacggcatcacccactttgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggactgacgtcctttactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaatctggtgctgggtgtcctgagcggggaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggag
gaggacctccggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctttggatgaaggaggctctgacacagagagcctgtatgaa
atcgagggcttgaacaaaatcatccagttcgtccgccactggaggcagtggaaccgtatc
tttcgttggaagtgccacgatgtgatcaagtccagagtcttctattggctggtgatcctg
atcgttgccctcaacaccctgtctatcgcctcagagcaccacaaccagcctctctggctg
acccatttgcaagacattgccaaccgcgtgctgctggccctcttcaccatcgagatgctg
atgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggaatcctggagatcctgctggtggagtcgggagccatgacc
cccctgggcatttctgtgctgcgttgcatccgcctccttcggatcttcaagatcaccaag
tattggacgtcactgagcaacctggtggcatccctgctcaactccatccgctccatcgcc
tccctgctgctgctgctcttcctcttcatcatcatctttgccctcctgggcatgcagctc
ttcggaggcaggtatgacttcgaggacacggaggtgcggcgcagcaactttgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctaacaggtgaagactggaactctgtgatg
tacaatgggatcatggcctacggcgggccgtcctaccctggggtgctcgtgtgcatttat
ttcatcatcctttttgtctgtggcaattatatcctgctcaatgtcttcctggccattgct
gtggacaacctggctgaggcagagagcctgacttctgcccagaaggccaaagcggaggag
agaaaacgcaggaagatgtccaagggtcttccagacaagtcagaggaagagaagtcagtg
atggccaagaagctggaacagaaacccaaaggtgaaggcatccctaccactgccaagctg
aaaatcgacgaatttgaatctaatgtcaatgaagtgaaggatccctacccctcagctgac
ttcccaggcgatgatgaggaagatgagcctgagatcccagtgagcccccgaccacgcccc
ctggctgagctgcagctcaaagagaaggcagtgcccatcccagaagccagttccttcttc
atcttcagccccaccaacaagatccgtgtcttttgtcatcgcattgtcaacgctacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagtgccgcgctggccgctgaggat
cccatccgggccgagtctgtgaggaatcagatccttgggtattttgacattgcattcacc
tctgtcttcactgtggagattgtcctcaagatgacaacctacggtgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtccctc
atctccatgggacttgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctccggcccctccgggccatcaacagagccaaaggactgaagcacgtggtgcagtgt
gtgtttgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgtttgcctgcatcggcgtccagcttttcaaggggaaattcttcagctgcaatgactta
tctaagatgacagaaaaggagtgcaggggctactactatgtgtacaaggatggggacccc
acgcagatggagctgcgtccccgccagtggatacatagcgacttccattttgacaacgtg
ctctcagccatgatgtcactcttcacagtctccacctttgagggatggcctcagctgctt
taccaggccatagatgcctacaaggaagacacgggccctgtctataattaccgagtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggttttgtcatcgtcaccttccaggagcagggggagactgagtacaagaactgtgag
ctggacaagaaccagcgccagtgtgtgcagtacgccctgaaggcccgcccgctgaggtgc
tacatccccaaaaacccataccagtaccaggtgtggtacatcgttacctcctcctacttt
gaatacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtcagaggagatgaaccacatctcagacatcctcaatgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgattgtcattggcagcatcatcgatgtcatcctcagt
gaaatcgacactttcctggcctccagcgggggactgtattgcctgggcggaggctgcggg
aacgttgacccagacgagagtgcccgcatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgcgcagagggagtacgcactctgctgtggacgttc
atcaagtccttccaggccctgccgtatgtggccctgctcatcgtcatgctcttcttcatc
tacgctgtcatcggcatgcagatgtttggtaaaatcgccatggtggacgggacccagata
aaccggaacaacaacttccagacctttccacaagctgtgctactgctcttcaggtgcgcg
acgggtgaggcgtggcaggaaatcctgttggcctgcagctacggcaagttgtgtgacccc
gaatcggattttgccccaggcgaggagtatacgtgtggcaccaactttgcctactactac
ttcatcagcttctacatgctctgtgccttcctgatcatcaacctgtttgtagctgtcatc
atggacaactttgactatctcacccgggactggtctatcctgggcccacatcacctggat
gagttcaaagccatttgggcagagtatgacccggaggcaaagggcagaatcaaacacctt
gatgtggtgaccctgctgagacggatccagccccctctgggctttgggaagttctgccca
caccgggtagcatgtaagcggctggtgggcatgaacatgcccttgaacagcgatggcaca
gtcaccttcaatgccactctcttcgccctggtccgcacagcactcaagatcaagacagaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaaacttctggaccaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctatgccacgtttctcatccaggagcacttccggaagtttatgaagcgccag
gaagagtattatgggtatcggcccaagaaggacactatacagatccaggccggattgcgg
accattgaggaagaggcagccccagagatccggcgcaccatctcaggagacctgacagct
gaagaggagctggagagagccatggtggaggccgccatggaggaagggatattccggagg
accggaggcctgtttggccaggtggacaacttcatggaaaggaccaactccctgccccct
gtcatggccaaccagagacccctccagtttgctgagatagagatggaagagctggaatca
cccgtcttcttggaggatttccctcaagatccacgcaccaaccctcttgctcatgccaat
accaacaatgccaatgccaatgttgcctatgacaacagcaaccatagcaacagccaggtg
ttttccagcttccgctatgagagggagttccctggagagacagagccgcctgctgcccga
gggggagtctttggccaaccccaaagggtcctgggagcccacagcaaatcctgtgtggaa
aagctaaaaggacagctgacccagatagaagggcccagggcccgggcatctcctaccccc
tgccagcatgccagggcagagcctcccctgcctgaagagaggagggaccccaccccaggg
cctgaggatgcaccccacagcggtaggaccaaggagaatagttccaggtgccagactcca
gctacggcccggctgattcaggaggctctggttcgaggaggcctggacaccttggcggcc
gatgctgactttgtcatggtgacaggccaggccctggcagatgcctgccagatggaacca
gaggacgtggaggtggcagcaacagagctactgaaaagtcaaggatccccagagggcatg
gccagtgcccagggacgcttgagcctcaggtcctcgctgggtagcctcgaccagcatcag
ggctcccaggagaccctgctcccccccaggatgtga
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integrated database retrieval system
