Hylobates moloch (silvery gibbon): 116466852 Help Entry 116466852         CDS       T08803                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism hmh  Hylobates moloch (silvery gibbon) Pathway hmh00230   Purine metabolism hmh01100   Metabolic pathways hmh01522   Endocrine resistance hmh04015   Rap1 signaling pathway hmh04022   cGMP-PKG signaling pathway hmh04024   cAMP signaling pathway hmh04062   Chemokine signaling pathway hmh04072   Phospholipase D signaling pathway hmh04081   Hormone signaling hmh04082   Neuroactive ligand signaling hmh04114   Oocyte meiosis hmh04211   Longevity regulating pathway hmh04213   Longevity regulating pathway - multiple species hmh04261   Adrenergic signaling in cardiomyocytes hmh04270   Vascular smooth muscle contraction hmh04371   Apelin signaling pathway hmh04540   Gap junction hmh04611   Platelet activation hmh04713   Circadian entrainment hmh04714   Thermogenesis hmh04723   Retrograde endocannabinoid signaling hmh04724   Glutamatergic synapse hmh04725   Cholinergic synapse hmh04726   Serotonergic synapse hmh04727   GABAergic synapse hmh04728   Dopaminergic synapse hmh04750   Inflammatory mediator regulation of TRP channels hmh04911   Insulin secretion hmh04912   GnRH signaling pathway hmh04913   Ovarian steroidogenesis hmh04914   Progesterone-mediated oocyte maturation hmh04915   Estrogen signaling pathway hmh04916   Melanogenesis hmh04918   Thyroid hormone synthesis hmh04921   Oxytocin signaling pathway hmh04923   Regulation of lipolysis in adipocytes hmh04924   Renin secretion hmh04925   Aldosterone synthesis and secretion hmh04926   Relaxin signaling pathway hmh04927   Cortisol synthesis and secretion hmh04928   Parathyroid hormone synthesis, secretion and action hmh04934   Cushing syndrome hmh04935   Growth hormone synthesis, secretion and action hmh04970   Salivary secretion hmh04971   Gastric acid secretion hmh04972   Pancreatic secretion hmh04976   Bile secretion hmh05012   Parkinson disease hmh05030   Cocaine addiction hmh05031   Amphetamine addiction hmh05032   Morphine addiction hmh05034   Alcoholism hmh05163   Human cytomegalovirus infection hmh05166   Human T-cell leukemia virus 1 infection hmh05200   Pathways in cancer hmh05207   Chemical carcinogenesis - receptor activation hmh05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:hmh00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     116466852 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     116466852 (ADCY5)    04371 Apelin signaling pathway     116466852 (ADCY5)    04072 Phospholipase D signaling pathway     116466852 (ADCY5)    04024 cAMP signaling pathway     116466852 (ADCY5)    04022 cGMP-PKG signaling pathway     116466852 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     116466852 (ADCY5)    04081 Hormone signaling     116466852 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     116466852 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     116466852 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     116466852 (ADCY5)    04062 Chemokine signaling pathway     116466852 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     116466852 (ADCY5)    04923 Regulation of lipolysis in adipocytes     116466852 (ADCY5)    04912 GnRH signaling pathway     116466852 (ADCY5)    04913 Ovarian steroidogenesis     116466852 (ADCY5)    04915 Estrogen signaling pathway     116466852 (ADCY5)    04914 Progesterone-mediated oocyte maturation     116466852 (ADCY5)    04921 Oxytocin signaling pathway     116466852 (ADCY5)    04926 Relaxin signaling pathway     116466852 (ADCY5)    04935 Growth hormone synthesis, secretion and action     116466852 (ADCY5)    04918 Thyroid hormone synthesis     116466852 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     116466852 (ADCY5)    04916 Melanogenesis     116466852 (ADCY5)    04924 Renin secretion     116466852 (ADCY5)    04925 Aldosterone synthesis and secretion     116466852 (ADCY5)    04927 Cortisol synthesis and secretion     116466852 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     116466852 (ADCY5)    04270 Vascular smooth muscle contraction     116466852 (ADCY5)   09154 Digestive system    04970 Salivary secretion     116466852 (ADCY5)    04971 Gastric acid secretion     116466852 (ADCY5)    04972 Pancreatic secretion     116466852 (ADCY5)    04976 Bile secretion     116466852 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     116466852 (ADCY5)    04727 GABAergic synapse     116466852 (ADCY5)    04725 Cholinergic synapse     116466852 (ADCY5)    04728 Dopaminergic synapse     116466852 (ADCY5)    04726 Serotonergic synapse     116466852 (ADCY5)    04723 Retrograde endocannabinoid signaling     116466852 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     116466852 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     116466852 (ADCY5)    04213 Longevity regulating pathway - multiple species     116466852 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     116466852 (ADCY5)    04714 Thermogenesis     116466852 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     116466852 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     116466852 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     116466852 (ADCY5)    05163 Human cytomegalovirus infection     116466852 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     116466852 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     116466852 (ADCY5)    05031 Amphetamine addiction     116466852 (ADCY5)    05032 Morphine addiction     116466852 (ADCY5)    05034 Alcoholism     116466852 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     116466852 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     116466852 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     116466852 (ADCY5) Enzymes [BR:hmh01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      116466852 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC HILPDA Motif Other DBs NCBI-GeneID:  116466852 NCBI-ProteinID:  XP_032005895 LinkDB All DBs Position Unknown AA seq 1264 aa AA seqDB search MSGSKSVSPPGYAAQKTAAPAPRGGPEHRSAWGEADSRANGYPHAPGGSARGSTKKPVGA VTPQQQQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRR QRRGAASGGSTRAPPAGGGGGSAAAAASAGGTEVRPRSVEVGLEERRGKGRAADELEAGA VEGGEGSGDGGSSADSGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRL NQSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILIMAVLCNRAAFHQDH MGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLL SALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQA RLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEG FTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCC VEMGLDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEA GGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIA KMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVD EFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICF VQITIVPHSVFMLSFYLTCSLLLTLVVFVSVIYSCVKLFPSPLQTLSRKIVRSKMNSTLV GVFTITLVFLAAFVNMFTCNSRDLLGCLAQEHNISASQVNACHVVESAVNYSLGDEQGFC GSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDN ADLLVTANAIDFFNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFL WKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASI ANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLND STYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYD IWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGG PPLS NT seq 3795 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgcggcgcaaaagactgcggcgccg gcgccccggggaggccctgaacaccgctcggcgtggggcgaggccgattcccgcgcgaat ggctacccccatgcccccgggggttctgcccgcggctccaccaagaaacccgtgggggcg gtgaccccgcagcagcagcagcagcagcagcgcctggccagccgctggcgcagcgacgac gacgacgatcctccgctgagcggtgacgaccccctggccgggggcttcggcttcagcttc cgctccaagtccgcctggcaggagcgcggcggcgacgactgcggtcgcggcagccgccgg cagcggcggggcgcggccagcgggggcagcacccgggcgccccctgcgggcggcggcggc ggctcggcggcggcggctgcctcggcgggcgggacggaggtgcgccctcgctcggtggag gtgggtctggaggagcggcggggcaaggggcgcgcggccgacgagctggaggccggcgcc gtcgagggcggcgaggggtccggggatggcggcagctcggcggactcgggctcgggcgcg gggcccggcgcggtgctgtccctgggcgcctgctgcctggcgttgctgcagatattccgc tccaagaagttcccgtcggacaaactggagcggctgtaccagcgctatttcttccgcctg aaccagagcagcctcaccatgctcatggccgtgctggtgctcgtgtgcctggtcatgttg gccttccacgcggcgcggcccccgctccagctgccctacctggccgtgctggcggccgcc gtgggcgtgatcctcatcatggctgtgctttgcaaccgcgccgccttccaccaggaccac atgggcctggcctgctatgcgctcatcgccgtggtgctggccgtccaggtggtgggcctg ctgctgccgcagccgcgcagcgcctctgagggcatctggtggaccgtgttcttcatctac accatctacacgctgctgcccgtgcgcatgcgggccgcagtgctcagcggggtgctcctg tccgccctccacctggccatcgccctgcgcaccaacgcccaggaccagttcctgctgaag cagcttgtctccaatgttctcattttctcctgcaccaacatcgtgggtgtctgcacccac tatccggctgaggtctcccagagacaggctttccaggagacccgagagtgcatccaggcg cggctccactctcagcgggagaaccagcagcaggaacggctcctgctgtctgtccttccc cgtcatgttgccatggagatgaaagcagacatcaacgccaagcaggaggatatgatgttc cataagatttacatccagaaacatgacaacgtgagcatcctgtttgctgacatcgagggc ttcactagcctggcgtcccagtgcactgcacaggaactggtcatgaccctcaacgagctc ttcgcccgctttgacaagctggccgcagagaatcactgtttacgtattaagatcctcggg gattgttattactgcgtctcggggctgcctgaagcgagggctgaccacgcccactgctgc gtggagatgggcttggacatgattgaggccatctcgttggtccgggaggtgacaggggtg aacgtgaacatgcgtgtgggaattcacagcgggcgagtacactgcggtgtccttggtctc aggaagtggcagttcgacgtctggtctaatgacgtcacgctagccaaccacatggaggct ggcggcaaggcgggacgcatccacatcaccaaggctacactcaactacctgaatggggac tacgaggtggagccaggctgtgggggcgagcgcaacgcctacctcaaagagcacagtatc gagaccttcctcatcctgcgctgcacccagaagcggaaagaagagaaggccatgatcgcc aagatgaaccgccagagaaccaactccatcgggcataacccaccacactggggggctgag cgccccttctacaaccacctgggtggcaaccaggtgtccaaggagatgaagcggatgggc tttgaagaccccaaggacaagaacgcccaggagagtgcgaaccctgaggacgaagtggat gagtttctgggccgtgccattgacgccaggagcatcgacaggcttcggtctgagcacgtc cgcaagttcctcctgaccttcagggagcctgacttagagaagaagtactccaagcaggta gacgaccgatttggtgcctatgtggcgtgtgcctcgctcgtcttcctcttcatctgcttt gtgcagatcaccatcgtgccccactccgtattcatgctcagcttctacctgacctgttcc ctgctgctgaccttggtggtgtttgtgtctgtgatctactcctgcgtaaagctcttcccc tccccgctgcagaccctatccaggaagatcgtgcggtccaagatgaacagcaccctggtt ggggtgttcaccatcaccctggtgttcctggcggcttttgtcaacatgttcacgtgcaac tccagggacctgctgggctgcttggcacaggagcacaacatcagcgcgagccaggtcaac gcatgtcacgtggtggagtcggccgtcaactacagcctgggcgatgagcagggcttctgt ggcagcccctggcccaactgcaacttccccgagtacttcacctacagcgtgctgctcagc ctgctggcctgctccgtgttcctgcagatcagctgcatcgggaagctggtgttaatgctg gccatcgagctcatctacgtgctcatcgtggaggtaccaggtgtcacgctcttcgacaac gccgacctgctggtcaccgccaacgccatagacttcttcaacaacgggacctcccagtgc cctgagcacgcaaccaaggtggcattgaaggtggtgacgcccatcatcatctcagtcttt gtgctggccctgtacctgcacgcccagcaggtggagtccactgcccgcctcgacttcctc tggaaactgcaggccacagaggagaaggaggagatggaggagctgcaggcctacaaccgg cggctgctgcacaacatcctgcccaaggatgtggccgctcacttcctggcccgcgagcgg cgcaatgatgagctctattatcagtcctgtgagtgtgtggcggtcatgtttgcctccatt gccaacttctccgagttctacgttgagctggaggccaacaacgagggtgtcgagtgcctg cggctactcaatgagatcatcgctgactttgatgagatcatcagcgaggatcggttccgg cagctggagaagatcaagaccatcggcagcacctacatggccgcctctggcctcaacgac tctacctacgacaaggtgggcaagacccacatcaaggcactggccgactttgccatgaag ctgatggaccagatgaagtacatcaatgagcactccttcaacaacttccagatgaagatc gggctcaacatcggccccgtggtggccggggtgataggggcacgaaagcctcagtacgac atctggggcaataccgtgaacgtggccagccgcatggacagcaccggtgtacccgaccgc atccaggtcaccacagacatgtaccaggtgctggctgccaacacgtaccagctggagtgc cggggcgtggtcaaggtcaagggcaaaggcgagatgatgacctacttcctcaatggaggg cccccgctcagttag

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