KEGG   PATHWAY: hpa00540Help
Entry
hpa00540                    Pathway                                

Name
Lipopolysaccharide biosynthesis - Helicobacter pylori HPAG1
Class
Metabolism; Glycan biosynthesis and metabolism
BRITE hierarchy
Pathway map
hpa00540  Lipopolysaccharide biosynthesis
hpa00540

Ortholog table
Module
hpa_M00063  CMP-KDO biosynthesis [PATH:hpa00540]
hpa_M00064  ADP-L-glycero-D-manno-heptose biosynthesis [PATH:hpa00540]
Other DBs
BSID: 35643
GO: 0009103
Organism
Helicobacter pylori HPAG1 [GN:hpa]
Gene
HPAG1_1321  UDP-N-acetylglucosamine acyltransferase [KO:K00677] [EC:2.3.1.129]
HPAG1_0395  UDP-3-0-acyl N-acetylglucosamine deacetylase [KO:K02535] [EC:3.5.1.108]
HPAG1_0190  UDP-3-0-(3-hydroxymyristoyl) glucosamine N-acyltransferase [KO:K02536] [EC:2.3.1.191]
HPAG1_0998  hypothetical protein [KO:K03269] [EC:3.6.1.54]
HPAG1_0850  lipid A disaccharide synthetase [KO:K00748] [EC:2.4.1.182]
HPAG1_0332  putative tetraacyldisaccharide-1-P 4-kinase [KO:K00912] [EC:2.7.1.130]
HPAG1_1354  polysialic acid capsule expression protein [KO:K06041] [EC:5.3.1.13]
HPAG1_0003  3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase [KO:K01627] [EC:2.5.1.55]
HPAG1_1519  ABC transporter system inner membrane protein [KO:K03270] [EC:3.1.3.45]
HPAG1_0233  3-deoxy-manno-octulosonate cytidylyltransferase [KO:K00979] [EC:2.7.7.38]
HPAG1_0941  3-deoxy-d-manno-octulosonic-acid transferase [KO:K02527] [EC:2.4.99.15 2.4.99.14 2.4.99.13 2.4.99.12]
HPAG1_0282  putative lipid A biosynthesis acyltransferase [KO:K02517] [EC:2.3.1.241]
HPAG1_0840  phosphoheptose isomerase [KO:K03271] [EC:5.3.1.28]
HPAG1_0841  ADP-heptose synthase [KO:K03272] [EC:2.7.7.70 2.7.1.167]
HPAG1_0843  hypothetical protein [KO:K03273] [EC:3.1.3.83 3.1.3.82]
HPAG1_0842  ADP-L-glycero-D-mannoheptose-6-epimerase [KO:K03274] [EC:5.1.3.20]
HPAG1_0281  lipopolysaccharide heptosyltransferase-1 [KO:K02841] [EC:2.4.-.-]
HPAG1_1132  ADP-heptose-lps heptosyltransferase II [KO:K02843] [EC:2.4.-.-]
HPAG1_1342  lipopolysaccharide 1,2-glucosyltransferase [KO:K03279] [EC:2.4.1.58]
HPAG1_0157  lipopolysaccharide 1,2-glycosyltransferase [KO:K03279] [EC:2.4.1.58]
HPAG1_0408  hypothetical protein [KO:K02847] [EC:2.4.1.-]
Compound
C00043  UDP-N-acetyl-alpha-D-glucosamine
C00199  D-Ribulose 5-phosphate
C00229  Acyl-carrier protein
C01112  D-Arabinose 5-phosphate
C01187  3-Deoxy-D-manno-octulosonate
C04121  CMP-3-deoxy-D-manno-octulosonate
C04478  3-Deoxy-D-manno-octulosonate 8-phosphate
C04652  UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine
C04738  UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine
C04824  Lipid X
C04919  2,3,2'3'-Tetrakis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-glucosamine 1,4'-bisphosphate
C04932  Lipid A disaccharide
C05223  Dodecanoyl-[acyl-carrier protein]
C05382  Sedoheptulose 7-phosphate
C05761  Tetradecanoyl-[acp]
C06022  UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine
C06024  3-Deoxy-D-manno-octulosonyl-lipid IV(A)
C06025  Di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)
C06026  Di[3-deoxy-D-manno-octulosonyl]-lipid A
C06251  Lauroyl-KDO2-lipid IV(A)
C06397  ADP-D-glycero-beta-D-manno-heptose
C06398  ADP-L-glycero-beta-D-manno-heptose
C07836  D-glycero-beta-D-manno-Heptose 7-phosphate
C07838  D-glycero-beta-D-manno-Heptose 1-phosphate
C11472  D-glycero-beta-D-manno-Heptose 1,7-bisphosphate
C19877  4-O-Phospho-alpha-Kdo-(2->6)-lipid IVA
C19878  D-glycero-alpha-D-manno-Heptose 7-phosphate
C19879  D-glycero-alpha-D-manno-Heptose 1,7-bisphosphate
C19880  D-glycero-alpha-D-manno-Heptose 1-phosphate
C19881  GDP-D-glycero-alpha-D-manno-heptose
Reference
PMID:9791168
  Authors
Heinrichs DE, Yethon JA, Whitfield C.
  Title
Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica.
  Journal
Mol Microbiol 30:221-32 (1998)
DOI:10.1046/j.1365-2958.1998.01063.x
Reference
  Authors
Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P.
  Title
Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli.
  Journal
J Bacteriol 184:363-9 (2002)
DOI:10.1128/JB.184.2.363-369.2002
Reference
PMID:9587193
  Authors
Wyckoff TJ, Raetz CR, Jackman JE.
  Title
Antibacterial and anti-inflammatory agents that target endotoxin.
  Journal
Trends Microbiol 6:154-9 (1998)
DOI:10.1016/S0966-842X(98)01230-X
Reference
PMID:9765561
  Authors
Shibayama K, Ohsuka S, Tanaka T, Arakawa Y, Ohta M.
  Title
Conserved structural regions involved in the catalytic mechanism of Escherichia coli K-12 WaaO (RfaI).
  Journal
J Bacteriol 180:5313-8 (1998)
KO pathway
ko00540   
LinkDB All DBs

DBGET integrated database retrieval system