KEGG   Hafnia paralvei: AL518_05260
Entry
AL518_05260       CDS       T05667                                 
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase II
  KO
K12525  bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:2.7.2.4 1.1.1.3]
Organism
hpar  Hafnia paralvei
Pathway
hpar00260  Glycine, serine and threonine metabolism
hpar00261  Monobactam biosynthesis
hpar00270  Cysteine and methionine metabolism
hpar00300  Lysine biosynthesis
hpar01100  Metabolic pathways
hpar01110  Biosynthesis of secondary metabolites
hpar01120  Microbial metabolism in diverse environments
hpar01230  Biosynthesis of amino acids
Module
hpar_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
hpar_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
hpar_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:hpar00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    AL518_05260 (metL)
   00270 Cysteine and methionine metabolism
    AL518_05260 (metL)
   00300 Lysine biosynthesis
    AL518_05260 (metL)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    AL518_05260 (metL)
Enzymes [BR:hpar01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     AL518_05260 (metL)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     AL518_05260 (metL)
SSDB
Motif
Pfam: Homoserine_dh AA_kinase NAD_binding_3 HTH_11
Other DBs
NCBI-ProteinID: AMH17470
LinkDB
Position
complement(1164615..1167050)
AA seq 811 aa
MSAQPVAGQAVGRQLHKFGGSSLADVKCYLRVAGIMAEYSFPGDMMVVSAAGSTTNQLIS
WLRLSQTDRISAHQVQQALRRYQSELITGLLPAELAEPLVARFTSDLERLATLLDEPMCD
ATYAEVVGHGEIWSARLMSALLNVKGMESEWLDARDFLRAERSAQPQVDEGRSYPLLQQL
LAQHPNKRLVATGFISRNDAGETVLLGRNGSDYSATQIGSLAGVSRVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSASDIDLQLRCSYQPEQGSTRIE
RVLASGTGAKIVTSHDEVCLIELNVPQSHDFENVRQEVDRVLKRSQLRPLATGVHRDRHM
IQLCYTAEVVGSALKLLEESGVPGLLQLREGLALVALVGAGVCKNPLHSHRFYQQLKDQP
IEFFCQSEDSISLVAVLRRGPTEALIQGLHTSLFRAEKRVGLVLMGKGNIGSRWLELFAR
EQENISARSGFEFVLAGVVDSSRSLLNYEGLDASRALAFFDDEAQEMDEENLFLWMRAHP
YDDLVVLDVTASESLAQQYRDFASYGFHVISANKLAGASGSDEYRQIRDAFEKTGRHWLY
NATVGAGLPVNYTVRDLRDSGDSILSISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGCESGSIDHFFENGEDLN
EQMIQRLEAANELGLVLRYAARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLAALL
NT seq 2436 nt   +upstreamnt  +downstreamnt
atgagcgcacaaccggtagctgggcaggcggtaggacgccaactgcataagtttggcggc
agtagtttagccgatgtgaaatgttatctgcgcgtcgcggggatcatggcggagtatagc
ttccctggcgatatgatggtcgtttccgccgcaggtagcaccaccaaccagcttattagc
tggttgaggctgagccaaactgaccggatctctgctcatcaggtacagcaggcgctgcgc
cgctatcagtcggaattgatcactggcttgctgcctgccgaattggccgagcctctggtt
gcgcgttttacttcagatctggagcgtttggccacattgctcgatgaacctatgtgcgat
gcaacctacgctgaggtggtcggacacggtgagatctggtcggcacgtctgatgtctgca
ctactaaacgtcaaaggcatggagtcagaatggcttgatgcacgcgatttcctccgcgcc
gagcgctccgctcagccgcaggtggacgaaggtcgctcttatcctctgttacagcaactg
ttggcgcagcatcccaataagcgtttggttgctaccggttttatcagccgcaacgatgca
ggagaaaccgtactgctgggacgtaacggttccgactactctgcaacccaaatcggctca
ctggccggcgtttcccgtgtcacgatctggagtgacgtagccggtgtgtacagcgccgac
ccacgtaaggttaaagatgcttgtctgctgccgctgctgcgcttagatgaagccagtgaa
ctggcacgtttagccgcgccggtgctgcatgcgcgtactttgcagccagtttccgctagc
gatatcgatctgcagctgcgttgtagctaccagccagagcagggctcgacgcgcattgag
cgcgtcttagcttccggcaccggtgccaaaatagttaccagccatgatgaagtttgcctg
attgaactcaacgttccgcaaagccatgattttgaaaacgtacgtcaagaagttgatcgt
gtgctgaagcgttcacagctgcgaccgttagccactggcgtacatcgcgaccgtcatatg
attcagctgtgctataccgcagaggtcgttggcagcgcactgaaactgctagaagagtct
ggcgtaccgggactgttgcagttgcgcgaaggtttggctctggttgcgttagtcggcgct
ggcgtatgcaagaatccactgcatagccaccgtttctatcagcagctaaaagatcagcca
atcgaattcttctgccagtcggaagacagtatcagcttagtagccgtattacgccgtggc
ccaaccgaagcgttgattcaagggctgcataccagcctgttccgtgctgaaaagcgcgtc
gggctggtgttaatgggcaaaggcaatatcggctcccgctggttagagctgtttgcccgt
gagcaggaaaatatttcggctcgtagcggatttgaatttgtgctggcaggcgtggtcgat
agcagccgaagtttgctcaattatgaaggattagatgccagccgtgcattggcattcttc
gatgatgaagcgcaggaaatggatgaagaaaatctgttcctgtggatgcgtgcccatcct
tacgacgatttagtggtgttagatgttacggccagtgaatcgctggcacagcagtatcgt
gattttgccagctatggtttccacgtcatcagcgccaataaattagcgggcgcatcaggc
agtgatgaatatcgccagatccgagatgcgtttgagaaaacgggtcgtcactggctgtat
aacgcaaccgtcggcgcgggcttaccggtaaactatacggtgcgcgatctacgcgacagc
ggtgactccattttgtccatcagcggaattttctccggtaccctgtcttggctattcctc
cagtttgatggcactgtgccatttaccgatttagtagaccaagcatggcagcaaggactc
accgaacccgatccacgcgtcgatctctctggccaagacgttatgcgcaagctagtgatt
ctggcacgtgaagcgggctacgatatcgagcctaatcaggttcgcgtggaatcactggta
cccgccggttgtgaaagcggttctatcgatcacttcttcgagaacggcgaagatttgaac
gagcagatgatccagcgcttagaagcggctaacgagctaggtttagtattgcgctatgcg
gcacgctttgatgctaacggtaaagctcgcgttggcgtagaagcagtacgtccagaacac
ccactggcagcgctgttaccgtgtgataacgtgtttgccattgaaagccgctggtatcgc
gataacccactggttattcgcggcccaggagcggggcgcgatgtgactgcgggagccatt
cagtcggatttgaaccggctggcagcgttattgtaa

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