KEGG   PATHWAY: hrt00330
Entry
hrt00330                    Pathway                                
Name
Arginine and proline metabolism - Hirundo rustica (Barn swallow)
Class
Metabolism; Amino acid metabolism
Pathway map
hrt00330  Arginine and proline metabolism
hrt00330

Module
hrt_M00015  Proline biosynthesis, glutamate => proline [PATH:hrt00330]
hrt_M00047  Creatine pathway [PATH:hrt00330]
hrt_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:hrt00330]
hrt_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:hrt00330]
hrt_M00970  Proline degradation, proline => glutamate [PATH:hrt00330]
hrt_M00972  Proline metabolism [PATH:hrt00330]
Other DBs
GO: 0006525 0006560
Organism
Hirundo rustica (Barn swallow) [GN:hrt]
Gene
120747722  [KO:K00128] [EC:1.2.1.3]
120747732  ALDH16A1; LOW QUALITY PROTEIN: aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
120747985  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
120748542  [KO:K00274] [EC:1.4.3.4]
120748718  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
120748767  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
120749037  [KO:K00274] [EC:1.4.3.4]
120750220  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
120750526  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
120753012  SMOX; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
120753557  LAP3; cytosol aminopeptidase isoform X1 [KO:K11142] [EC:3.4.11.1 3.4.11.5]
120753659  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
120753898  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
120754009  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
120754069  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
120754188  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
120754252  CARNS1; carnosine synthase 1 [KO:K14755] [EC:6.3.2.11]
120754326  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
120755545  ALDH18A1; LOW QUALITY PROTEIN: delta-1-pyrroline-5-carboxylate synthase [KO:K12657] [EC:2.7.2.11 1.2.1.41]
120755757  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
120755979  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
120755990  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
120756091  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X4 [KO:K00472] [EC:1.14.11.2]
120756289  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
120757746  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
120758526  CKMT1A; creatine kinase U-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
120758668  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
120759217  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
120760458  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
120760490  DAO; D-amino-acid oxidase isoform X1 [KO:K00273] [EC:1.4.3.3]
120760568  PRODH; proline dehydrogenase 1, mitochondrial isoform X1 [KO:K00318] [EC:1.5.5.2]
120760593  NOS1; nitric oxide synthase 1 isoform X1 [KO:K13240] [EC:1.14.13.39]
120760851  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
120761199  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
120761267  [KO:K00128] [EC:1.2.1.3]
120761366  [KO:K00128] [EC:1.2.1.3]
120762245  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
120762330  AGMAT; LOW QUALITY PROTEIN: guanidino acid hydrolase, mitochondrial [KO:K27001]
120763487  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
120764846  [KO:K00933] [EC:2.7.3.2]
120765118  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
120765397  P4HA3; prolyl 4-hydroxylase subunit alpha-3 [KO:K00472] [EC:1.14.11.2]
120765812  ALDH7A1; LOW QUALITY PROTEIN: alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
hrt00020  Citrate cycle (TCA cycle)
hrt00220  Arginine biosynthesis
hrt00250  Alanine, aspartate and glutamate metabolism
hrt00260  Glycine, serine and threonine metabolism
hrt00270  Cysteine and methionine metabolism
hrt00310  Lysine degradation
hrt00410  beta-Alanine metabolism
hrt00470  D-Amino acid metabolism
hrt00480  Glutathione metabolism
hrt00630  Glyoxylate and dicarboxylate metabolism
hrt00650  Butanoate metabolism
hrt00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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