KEGG   Homo sapiens (human): 10
Entry
10                CDS       T01001                                 
Symbol
NAT2, AAC2, NAT-2, PNAT
Name
(RefSeq) N-acetyltransferase 2
  KO
K00622  arylamine N-acetyltransferase [EC:2.3.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00232  Caffeine metabolism
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa05204  Chemical carcinogenesis - DNA adducts
Network
nt06250  DNA adduct formation
  Element
N01370  PhIP to DNA adducts
N01372  IQ to DNA adducts
N01373  MeIQx to DNA adducts
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    10 (NAT2)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    10 (NAT2)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    10 (NAT2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.5  arylamine N-acetyltransferase
     10 (NAT2)
SSDB
Motif
Pfam: Acetyltransf_2
Other DBs
NCBI-GeneID: 10
NCBI-ProteinID: NP_000006
OMIM: 612182
HGNC: 7646
Ensembl: ENSG00000156006
Pharos: P11245(Tbio)
UniProt: P11245 A4Z6T7
Structure
LinkDB
Position
8:18386301..18401218
AA seq 290 aa
MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIV
RRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYI
VDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHL
LPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILT
YRKFNYKDNTDLVEFKTLTEEEVEEVLRNIFKISLGRNLVPKPGDGSLTI
NT seq 873 nt   +upstreamnt  +downstreamnt
atggacattgaagcatattttgaaagaattggctataagaactctaggaacaaattggac
ttggaaacattaactgacattcttgagcaccagatccgggctgttccctttgagaacctt
aacatgcattgtgggcaagccatggagttgggcttagaggctatttttgatcacattgta
agaagaaaccggggtgggtggtgtctccaggtcaatcaacttctgtactgggctctgacc
acaatcggttttcagaccacaatgttaggagggtatttttacatccctccagttaacaaa
tacagcactggcatggttcaccttctcctgcaggtgaccattgacggcaggaattacatt
gtcgatgctgggtctggaagctcctcccagatgtggcagcctctagaattaatttctggg
aaggatcagcctcaggtgccttgcattttctgcttgacagaagagagaggaatctggtac
ctggaccaaatcaggagagagcagtatattacaaacaaagaatttcttaattctcatctc
ctgccaaagaagaaacaccaaaaaatatacttatttacgcttgaacctcgaacaattgaa
gattttgagtctatgaatacatacctgcagacgtctccaacatcttcatttataaccaca
tcattttgttccttgcagaccccagaaggggtttactgtttggtgggcttcatcctcacc
tatagaaaattcaattataaagacaatacagatctggtcgagtttaaaactctcactgag
gaagaggttgaagaagtgctgagaaatatatttaagatttccttggggagaaatctcgtg
cccaaacctggtgatggatcccttactatttag

KEGG   Homo sapiens (human): 9
Entry
9                 CDS       T01001                                 
Symbol
NAT1, AAC1, MNAT, NAT-1, NATI
Name
(RefSeq) N-acetyltransferase 1
  KO
K00622  arylamine N-acetyltransferase [EC:2.3.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00232  Caffeine metabolism
hsa00983  Drug metabolism - other enzymes
hsa01100  Metabolic pathways
hsa05204  Chemical carcinogenesis - DNA adducts
Network
nt06250  DNA adduct formation
  Element
N01369  4-ABP to DNA adducts
N01372  IQ to DNA adducts
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00232 Caffeine metabolism
    9 (NAT1)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    9 (NAT1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    9 (NAT1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.5  arylamine N-acetyltransferase
     9 (NAT1)
SSDB
Motif
Pfam: Acetyltransf_2
Other DBs
NCBI-GeneID: 9
NCBI-ProteinID: NP_000653
OMIM: 108345
HGNC: 7645
Ensembl: ENSG00000171428
Pharos: P18440(Tchem)
UniProt: P18440
Structure
LinkDB
Position
8:18170467..18223689
AA seq 290 aa
MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVV
RRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYI
VDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDL
LEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLT
HRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI
NT seq 873 nt   +upstreamnt  +downstreamnt
atggacattgaagcatatcttgaaagaattggctataagaagtctaggaacaaattggac
ttggaaacattaactgacattcttcaacaccagatccgagctgttccctttgagaacctt
aacatccattgtggggatgccatggacttaggcttagaggccatttttgatcaagttgtg
agaagaaatcggggtggatggtgtctccaggtcaatcatcttctgtactgggctctgacc
actattggttttgagaccacgatgttgggagggtatgtttacagcactccagccaaaaaa
tacagcactggcatgattcaccttctcctgcaggtgaccattgatggcaggaactacatt
gtcgatgctgggtttggacgctcataccagatgtggcagcctctggagttaatttctggg
aaggatcagcctcaggtgccttgtgtcttccgtttgacggaagagaatggattctggtat
ctagaccaaatcagaagggaacagtacattccaaatgaagaatttcttcattctgatctc
ctagaagacagcaaataccgaaaaatctactcctttactcttaagcctcgaacaattgaa
gattttgagtctatgaatacatacctgcagacatctccatcatctgtgtttactagtaaa
tcattttgttccttgcagaccccagatggggttcactgtttggtgggcttcaccctcacc
cataggagattcaattataaggacaatacagatctaatagagttcaagactctgagtgag
gaagaaatagaaaaagtgctgaaaaatatatttaatatttccttgcagagaaagcttgtg
cccaaacatggtgatagattttttactatttag

DBGET integrated database retrieval system