Homo sapiens (human): 10055
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Entry
10055 CDS
T01001
Symbol
SAE1, AOS1, HSPC140, SUA1, UBLE1A
Name
(RefSeq) SUMO1 activating enzyme subunit 1
KO
K10684
ubiquitin-like 1-activating enzyme E1 A [EC:
6.2.1.45
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
Drug target
Subasumstat:
D12268
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
10055 (SAE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
10055 (SAE1)
Enzymes [BR:
hsa01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.45 E1 ubiquitin-activating enzyme
10055 (SAE1)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin-activating enzymes (E1)
UBL-activating enzymes
10055 (SAE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ThiF
Motif
Other DBs
NCBI-GeneID:
10055
NCBI-ProteinID:
NP_005491
OMIM:
613294
HGNC:
30660
Ensembl:
ENSG00000142230
Pharos:
Q9UBE0
(Tbio)
UniProt:
Q9UBE0
Structure
PDB
LinkDB
All DBs
Position
19:47130835..47210636
Genome browser
AA seq
346 aa
AA seq
DB search
MVEKEEAGGGISEEEAAQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGV
KGLTMLDHEQVTPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE
SFFTQFDAVCLTCCSRDVIVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTK
VAKVSQGVEDGPDTKRAKLDSSETTMVKKKVVFCPVKEALEVDWSSEKAKAALKRTTSDY
FLLQVLLKFRTDKGRDPSSDTYEEDSELLLQIRNDVLDSLGISPDLLPEDFVRYCFSEMA
PVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGMKGNGIVECLGPK
NT seq
1041 nt
NT seq
+upstream
nt +downstream
nt
atggtggagaaggaggaggctggcggcggcattagcgaggaggaggcggcacagtatgac
cggcagatccgcctgtggggactggaggcccagaaacggctgcgggcctctcgggtgctt
cttgtcggcttgaaaggacttggggctgaaattgccaagaatctcatcttggcaggagtg
aaaggactgaccatgctggatcacgaacaggtaactccagaagatcccggagctcagttc
ttgattcgtactgggtctgttggccgaaatagggctgaagcctctttggagcgagctcag
aatctcaaccccatggtggatgtgaaggtggacactgaggatatagagaagaaaccagag
tcatttttcactcaattcgatgctgtgtgtctgacttgctgctccagggatgtcatagtt
aaagttgaccagatctgtcacaaaaatagcatcaagttctttacaggagatgtttttggc
taccatggatacacatttgccaatctaggagagcatgagtttgtagaggagaaaactaaa
gttgccaaagttagccaaggagtagaagatgggcccgacaccaagagagcaaaacttgat
tcttctgagacaacgatggtcaaaaagaaggtggtcttctgccctgttaaagaagccctg
gaggtggactggagcagtgagaaagcaaaggctgctctgaagcgcacgacctccgactac
tttctccttcaagtgctcttaaagttccgtacagataaaggaagagatcccagttctgat
acatatgaggaagattctgagttgttgctccagatacgaaatgatgtgcttgactcactg
ggtattagtcctgacctgcttcctgaggactttgtcaggtactgcttctccgagatggcc
ccagtgtgtgcggtggttggagggattttggcacaggaaattgtgaaggccctgtctcag
cgggaccctcctcacaacaacttcttcttcttcgatggcatgaaggggaatgggattgtg
gagtgccttggccccaagtga
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