KEGG   Homo sapiens (human): 10120
Entry
10120             CDS       T01001                                 
Symbol
ACTR1B, ARP1B, CTRN2, PC3
Name
(RefSeq) actin related protein 1B
  KO
K16575  centractin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04814  Motor proteins
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N01159  Mutation-caused aberrant TUBA4A to retrograde axonal transport
N01160  Mutation-caused aberrant SOD1 to retrograde axonal transport
N01295  Rab7-regulated microtubule minus-end directed transport
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    10120 (ACTR1B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    10120 (ACTR1B)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    10120 (ACTR1B)
   05016 Huntington disease
    10120 (ACTR1B)
   05022 Pathways of neurodegeneration - multiple diseases
    10120 (ACTR1B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    10120 (ACTR1B)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10120 (ACTR1B)
   04147 Exosome [BR:hsa04147]
    10120 (ACTR1B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Dynactin complex
     10120 (ACTR1B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actins
    Actin-related proteins
     10120 (ACTR1B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   10120 (ACTR1B)
SSDB
Motif
Pfam: Actin
Other DBs
NCBI-GeneID: 10120
NCBI-ProteinID: NP_005726
OMIM: 605144
HGNC: 168
Ensembl: ENSG00000115073
Pharos: P42025(Tdark)
UniProt: P42025
LinkDB
Position
2:complement(97655939..97664044)
AA seq 376 aa
MESYDIIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHMRVMAGALEGDLFIGP
KAEEHRGLLTIRYPMEHGVVRDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPSKN
REKAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI
MRVDIAGRDVSRYLRLLLRKEGVDFHTSAEFEVVRTIKERACYLSINPQKDEALETEKVQ
YTLPDGSTLDVGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVL
SGGSTLFKGFGDRLLSEVKKLAPKDIKIKISAPQERLYSTWIGGSILASLDTFKKMWVSK
KEYEEDGSRAIHRKTF
NT seq 1131 nt   +upstreamnt  +downstreamnt
atggagtcctacgacatcatcgccaaccagcctgtggtcatcgacaacggttcgggggtg
attaaagctggctttgcaggagaccagattcccaaatactgtttcccaaactatgtcggg
cggccgaagcacatgcgggtgatggctggagccctggagggggacctcttcatcggacca
aaagcagaggagcaccgggggctgctgaccatccgctaccccatggagcacggcgtggtg
cgagactggaacgacatggaacgcatctggcagtacgtctactccaaggatcagctgcag
accttctcggaggagcatcctgtgctcctcacggaggccccgctcaacccgagtaagaac
cgggagaaggcggcagaggtgttctttgagaccttcaacgtgccggccctgttcatctcc
atgcaggctgtgctcagtctgtacgcaacaggacgcacgacaggagtggttctagactca
ggggacggggtcactcatgctgtgcccatctatgagggctttgccatgcctcactccatc
atgcgggtggacattgccggccgcgacgtctcccgctacctccgactcctgctgcgcaag
gaaggggttgacttccatacctcggctgagtttgaggttgtccggacaatcaaagagcga
gcgtgctacctgtccatcaacccacagaaggatgaggctctggagacggagaaggtgcag
tacacgttgccagacggcagcacgcttgatgtggggcctgcacgattccgggcccccgag
ctgctgttccagccggaccttgtcggggatgagagtgaggggctccatgaggtggtggcc
ttcgccatacacaagtccgacatggacctgcgccggacgctgttcgccaacatcgtgctc
tcaggtggctcaacgcttttcaaaggcttcggagaccgattactcagtgaagtgaagaag
cttgccccaaaggatatcaaaatcaagatctcagccccgcaggaacggctgtactccaca
tggattggcggctccatcctggcctcgctggacacttttaagaagatgtgggtgtccaaa
aaggagtatgaagaggatggctcccgtgctattcatcgcaaaactttctag

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