Homo sapiens (human): 10297
Help
Entry
10297 CDS
T01001
Symbol
APC2, APCL, MRT74
Name
(RefSeq) APC regulator of WNT signaling pathway 2
KO
K02085
adenomatosis polyposis coli protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04810
Regulation of actin cytoskeleton
hsa04934
Cushing syndrome
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05206
MicroRNAs in cancer
hsa05210
Colorectal cancer
hsa05213
Endometrial cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Disease
H00718
Sotos syndrome
H00768
Autosomal recessive intellectual developmental disorder
H01667
Medulloblastoma
H01881
Complex cortical dysplasia with other brain malformations
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
10297 (APC2)
04390 Hippo signaling pathway
10297 (APC2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
10297 (APC2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
10297 (APC2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
10297 (APC2)
05206 MicroRNAs in cancer
10297 (APC2)
09162 Cancer: specific types
05210 Colorectal cancer
10297 (APC2)
05225 Hepatocellular carcinoma
10297 (APC2)
05226 Gastric cancer
10297 (APC2)
05217 Basal cell carcinoma
10297 (APC2)
05213 Endometrial cancer
10297 (APC2)
05224 Breast cancer
10297 (APC2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
10297 (APC2)
09164 Neurodegenerative disease
05010 Alzheimer disease
10297 (APC2)
05022 Pathways of neurodegeneration - multiple diseases
10297 (APC2)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
10297 (APC2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
10297 (APC2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
10297 (APC2)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
10297 (APC2)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
10297 (APC2)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
10297 (APC2)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
10297 (APC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
APC_basic
APC_rep
APC_N_CC
APC_r
Arm
Arm_APC_u3
Suppressor_APC
SAMP
bZIP_1
Sec7-like_HUS
HALZ
CCDC138_cc
Motif
Other DBs
NCBI-GeneID:
10297
NCBI-ProteinID:
NP_005874
OMIM:
612034
HGNC:
24036
Ensembl:
ENSG00000115266
UniProt:
O95996
LinkDB
All DBs
Position
19:1446230..1473244
Genome browser
AA seq
2303 aa
AA seq
DB search
MASSVAPYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQE
ARVLVSSGQTEVLEQLKALQMDITSLYNLKFQPPTLGPEPAARTPEGSPVHGSGPSKDSF
GELSRATIRLLEELDRERCFLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQM
DLIRQQLEFEAQHIRSLMEERFGTSDEMVQRAQIRASRLEQIDKELLEAQDRVQQTEPQA
LLAVKSVPVDEDPETEVPTHPEDGTPQPGNSKVEVVFWLLSMLATRDQEDTARTLLAMSS
SPESCVAMRRSGCLPLLLQILHGTEAAAGGRAGAPGAPGAKDARMRANAALHNIVFSQPD
QGLARKEMRVLHVLEQIRAYCETCWDWLQARDGGPEGGGAGSAPIPIEPQICQATCAVMK
LSFDEEYRRAMNELGGLQAVAELLQVDYEMHKMTRDPLNLALRRYAGMTLTNLTFGDVAN
KATLCARRGCMEAIVAQLASDSEELHQVVSSILRNLSWRADINSKKVLREAGSVTALVQC
VLRATKESTLKSVLSALWNLSAHSTENKAAICQVDGALGFLVSTLTYKCQSNSLAIIESG
GGILRNVSSLVATREDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSARSARDQ
ELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLAHRPAKHQAAATAVSPGSCVPSLYV
RKQRALEAELDARHLAQALEHLEKQGPPAAEAATKKPLPPLRHLDGLAQDYASDSGCFDD
DDAPSSLAAAAATGEPASPAALSLFLGSPFLQGQALARTPPTRRGGKEAEKDTSGEAAVA
AKAKAKLALAVARIDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGPEG
GRREAGSRAHPLLRLKAAHASLSNDSLNSGSASDGYCPREHMLPCPLAALASRREDPRCG
QPRPSRLDLDLPGCQAEPPAREATSADARVRTIKLSPTYQHVPLLEGASRAGAEPLAGPG
ISPGARKQAWLPADHLSKVPEKLAAAPLSVASKALQKLAAQEGPLSLSRCSSLSSLSSAG
RPGPSEGGDLDDSDSSLEGLEEAGPSEAELDSTWRAPGATSLPVAIPAPRRNRGRGLGVE
DATPSSSSENYVQETPLVLSRCSSVSSLGSFESPSIASSIPSEPCSGQGSGTISPSELPD
SPGQTMPPSRSKTPPLAPAPQGPPEATQFSLQWESYVKRFLDIADCRERCRLPSELDAGS
VRFTVEKPDENFSCASSLSALALHEHYVQQDVELRLLPSACPERGGGAGGAGLHFAGHRR
REEGPAPTGSRPRGAADQELELLRECLGAAVPARLRKVASALVPGRRALPVPVYMLVPAP
APAQEDDSCTDSAEGTPVNFSSAASLSDETLQGPPRDQPGGPAGRQRPTGRPTSARQAMG
HRHKAGGAGRSAEQSRGAGKNRAGLELPLGRPPSAPADKDGSKPGRTRGDGALQSLCLTT
PTEEAVYCFYGNDSDEEPPAAAPTPTHRRTSAIPRAFTRERPQGRKEAPAPSKAAPAAPP
PARTQPSLIADETPPCYSLSSSASSLSEPEPSEPPAVHPRGREPAVTKDPGPGGGRDSSP
SPRAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSRERGEEAAGSDRASD
LDSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQ
AEGEMGSARRPEKRGAASVKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPA
PRAQPKGTPGPRATPRKVAPPCLAQPAAPAKVPSPGQQRSRSLHRPAKTSELATLSQPPR
SATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQAAGALPGPGASPVPKTPARTLLAKQ
HKTQRSPVRIPFMQRPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGRLGLVRVASALS
SGSESSDRSGFRRQLTFIKESPGLRRRRSELSSAESAASAPQGASPRRGRPALPAVFLCS
SRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAARPETVKRYA
SLPHISVARRPDGAVPAAPASADAARRSSDGEPRPLPRVAAPGTTWRRIRDEDVPHILRS
TLPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLETREPPGAPAG
GQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSPM
VVAATTDSAAEKAPATASATLLE
NT seq
6912 nt
NT seq
+upstream
nt +downstream
nt
atggcgagctccgtggcgccctacgagcagctggtgaggcaggtggaggccttgaaggct
gagaacagccacctgaggcaggagctaagggacaactccagccacctgtccaagctggag
acagagacgtcgggcatgaaggaggtcctgaagcacctacagggaaaactggagcaggag
gcccgagtgctggtgtcctcggggcagacggaggtgctggagcagctgaaggccctacag
atggacatcaccagcctgtacaacctcaagttccagccgcccaccctgggcccggagcct
gccgcccggacccccgagggcagcccagtacacggctccgggccctccaaggacagcttt
ggggagctgagccgggccaccatccggctgctggaggaactggaccgggaacggtgtttc
ctgctgaatgagattgagaaggaggagaaggagaagctctggtactactctcagctgcag
ggcctgtccaagcgcctggacgagctgccgcacgtggagacgcagttctcgatgcagatg
gacctgatccggcagcagcttgagttcgaggcccagcacatccgctcgctgatggaggag
cgcttcggcacctcggacgagatggtgcagcgggcacagatccgcgcctcgcgcctggag
cagattgacaaggagctgctggaggcgcaggaccgagtgcagcagacggagccccaggcc
ttgctggcggtgaagtcggtgccggtggacgaggaccccgagacagaggtccccacacac
cctgaggatggcacccctcagccgggcaacagcaaggtggaggtggtcttctggctgttg
tccatgttggcgacgcgcgaccaggaggatacagcgcgcacgctgctggccatgtccagc
tcgcccgagagctgcgtggccatgcgccgctcgggctgtctgcctctgctgctgcaaatc
ctccacggcaccgaggccgcggccgggggtcgcgccggggccccaggggcaccgggcgcc
aaggacgcacgcatgcgcgccaacgcggcgctgcacaacatcgtcttctcgcagccggac
cagggcctggcgcgcaaggagatgcgcgtcctgcacgtgctggagcagatccgggcctac
tgcgagacctgctgggactggctgcaggcccgagacggcgggcccgagggaggtggcgcc
ggcagcgccccgatccccatcgagccgcagatctgccaggccacctgtgctgttatgaag
ctgtcctttgatgaggagtaccgccgtgccatgaacgagctaggtgggctgcaggccgtg
gcagagctgctgcaggttgactatgagatgcacaagatgacccgggacccgctgaacctg
gcgctgcgccgctacgcgggcatgaccctcaccaacctcacctttggggacgttgccaac
aaggccaccctgtgtgcgcgccgcggctgcatggaggccatcgtggcccagctggcctcc
gacagtgaggagctccaccaggtggtgtccagcatccttcggaacttgtcctggagggcc
gacatcaacagcaagaaggtgctgagggaggcgggcagcgtgactgccctggtgcagtgt
gtcctgcgggccaccaaggagtccaccctgaagagcgtgctgagcgccctgtggaatctg
tctgcacacagcacagagaacaaggcggccatctgccaggtggatggcgccctgggcttc
ctggtgagcaccctgacctacaagtgtcagagcaactcgctggccatcatcgagagcggc
ggcggcatcctccgcaatgtgtccagcctcgtcgccacccgtgaggactacaggcaggtg
ctccgggatcacaactgtctgcagacgctgctgcagcatctgacttcgcacagcctgacc
atcgtgagcaacgcgtgcggcacgctctggaacctgtcggcccgcagcgcccgtgaccag
gagctgctgtgggacctgggcgccgtgggcatgctgcgtaatctggtgcactccaagcac
aagatgatcgccatgggcagcgccgccgccctgcgcaacctgctggcccatcggcccgcc
aagcaccaggcggccgccaccgccgtgtccccaggcagctgcgtgcccagcctgtacgtg
cgcaagcagcgggcgctggaggccgagctggacgcacggcacctcgcgcaggcgctggag
cacctggagaagcagggcccgccggcagccgaggccgccactaagaagccgctgccgccc
ctgcgacacctggacggcctggcccaagactatgcttccgattcgggctgctttgacgac
gacgatgcaccgtcatccctggctgcggccgcggccaccggggagccagccagccctgcc
gcgctgtccctcttcctgggcagccccttcctgcaggggcaggcgctggctcgcaccccg
cccacccgccgaggcggcaaggaggcagagaaggacaccagtggggaggcagccgtggcg
gccaaggccaaggccaagctggcgcttgcagtggcgcgcatcgaccagctggtggaggac
atctccgccctgcacacctcgtccgacgatagcttcagcctcagctctggagacccggga
caggaggcgccacgggagggccgcgcccagtcctgctcgccatgccgcggcccggagggc
gggcggcgagaggcaggaagccgggcgcacccgctgctgcggctcaaggcggcccacgcc
agcctctccaacgacagcctcaacagcggcagtgccagcgacgggtactgcccacgcgaa
catatgctgccctgcccgctggccgcactggcttcgcgccgcgaggaccccaggtgtggg
cagcctcggcccagccggcttgaccttgacctgcccggctgccaggccgagcccccggcc
cgcgaggccacctccgccgacgcccgcgtgcgcaccatcaagctgtcgcctacctatcag
cacgtgccactgcttgagggtgcctcaagggcgggtgcagagcccctcgcggggcctgga
atctctccaggggcccggaagcaggcctggctgccggcagaccacctgagcaaggttccc
gagaagctggcggctgccccgctgtctgtggccagcaaggcactgcagaaactggcggcg
caagaggggccactctcgctgtcccgatgcagctccctttcctcgctgtcctcggccggc
cgcccaggccccagcgagggtggtgacctggatgacagtgactcctccctggaggggctg
gaggaggccggccccagcgaggctgagctggacagcacgtggcgggcgcccggggccacc
tcgctgcccgtagccattccggctccccggcgtaaccgaggccggggcctgggggtggaa
gacgccacgccgtccagctcgtcggagaactacgtgcaggagacaccgcttgtgctgagc
cgctgcagctctgtgagctcgctgggcagcttcgagagcccgtccatcgccagctccatc
cccagtgaaccttgcagcgggcagggcagcggcaccatcagccctagcgagctgcccgac
agccccggacagaccatgcctcccagccggagcaagacgccaccgctggcgcccgcgcca
cagggtccccccgaggccacccagttcagcctgcagtgggagagctacgtgaagcgcttc
ctggacatcgccgactgccgggagcgctgccggctgccatctgagctggacgcaggcagc
gtgcgctttaccgtggagaagccagacgagaacttctcgtgcgcctccagcctcagcgcg
ctggccttgcacgagcactacgtgcagcaggacgtggagctgcggctgctgccctcggcc
tgccccgagcgcggcgggggcgccgggggcgccggcctccactttgcagggcaccggcgg
cgggaggaggggccggcgcccacgggttctcgccctcgcggcgccgcggaccaggagctg
gaactgctgcgggagtgcctgggagccgccgtgcctgcccggctgcgcaaggtggcctcc
gcgctggtgccaggtcgccgcgcactccccgtgcccgtctacatgttggtgcccgccccg
gccccggcccaggaggacgactcctgcactgactccgcggagggcacgccggtcaacttc
tctagcgccgcctcgctcagcgacgagacgctgcagggaccccccagggaccagcccggg
ggaccagcgggcaggcaaagacccaccggccgccccacctctgccagacaggccatgggg
caccggcacaaggcgggaggcgccggccgcagcgcggagcagtctcggggcgcgggcaag
aacagagcagggctggagctgcccctgggccggcccccgagcgcccccgcagacaaggac
ggctcaaagcccggccggacccgcggggacggggcgctccagtcgctgtgcctcacgacg
cccactgaggaggccgtgtactgcttctacggcaacgactcggacgaggagcccccggcg
gccgcgcccacgccaacccaccggcgcacatcggccatccctcgcgcttttacgcgggag
cgtccgcagggccggaaggaggcccctgccccgtccaaggctgcaccagctgccccgccg
cccgcccggacccagcccagcctcattgctgacgagaccccgccctgctactccctgagc
tcctccgccagctccctcagcgagcccgagccctcggagccgccggccgtccatccacga
ggccgggagcccgcggtcaccaaggacccgggcccaggaggcggacgcgacagctcgccc
agcccgcgggccgcggaggagcttctgcagcggtgcatcagctcggccctgcccaggcgc
cggccccccgtgtctggcctgcggcgccgcaagccccgagccacccggctggatgagcgg
cccgcagaggggtcccgggaacgcggcgaggaggcagcgggctcggaccgggcctccgac
ctggatagcgtggagtggcgcgccatccaggagggcgccaattcaattgtcacgtggctg
caccaggcagcagctgccacgcgggaggcctcgtccgagtccgactccatcctgtccttc
gtatccgggctgtcagtgggatccaccctacagccccccaagcacaggaagggacgacag
gcggagggagaaatgggcagtgcccggcggccagagaaaaggggcgcagcctcagtcaag
accagcgggagcccccgttcccctgcaggccccgagaagccacgtggcacacagaagacc
acgcccggggtgccagctgtgctccggggacgaacagtgatctacgtccccagcccggca
ccccgtgcccagcccaaagggacccccggcccccgcgccacaccgcggaaggtggcgccc
ccttgcctggcacagcccgcggctccagccaaagtcccgagccccgggcagcagcggtcg
cggagcctacaccggcctgccaagacctcggagctggcgacgctgagccagccccccaga
agcgccacaccgcccgcccgcctcgccaagaccccctcctccagctcctcccagacctcg
cccgcctcccagcccctgcccagaaagcgccccccggtcacccaggctgctggggccctg
cccggccccggagcctccccggtgcccaaaacgccggcgcgcacccttctggcgaagcag
cacaagacgcagagatcgcccgtgcggatcccgttcatgcagaggccggcccggcgtggg
ccgccaccgctggctcgggcagtcccggagccgggccccaggggccgggcggggaccgag
gcgggcccgggggcgcgcgggggccgcctgggcctggtgcgtgtggcctcagccctctcc
agcggcagcgagtcctccgaccgctcgggcttccggcgacagctaaccttcatcaaggag
tcgccgggcttgcggcgccgccgctccgagctgtcctcggccgagtccgcggcctctgcc
ccccagggcgcctcgccccgccgcggccggcccgcgctgcccgccgtcttcctctgctcc
tcgcgctgcgaagagctccgagcggcaccccggcagggcccggccccggcccggcagcgg
ccccccgcggcccgacccagccctggcgagcgccctgcccggcgcaccacctccgagagc
ccgtcccgcctgcctgtgcgcgcgcccgccgcccggccggagactgtcaagcgctacgcg
tcgctgccgcacatcagcgtggcccgcaggcccgacggcgccgtccccgcggcccctgcc
tcagccgacgccgcgcgccgcagcagcgacggggagccccggccgctccccagggtggcc
gcgccgggcacgacctggcggcgcatccgagatgaggacgtgccccacatcctgcgcagc
acgcttcccgccacggccctgccactgcggggctccacgcccgaggacgccccggccggg
cccccgccgcgcaagaccagcgacgccgtggtccagaccgaggaggtcgccgcccccaag
accaactccagcacgtccccgagcctggagaccagggagccccccggggcccccgccggc
ggccagctctccctcctcggcagcgacgtggacggtcccagcctcgccaaggctcccatc
tccgcacccttcgtgcacgagggcctgggggtcgccgtggggggcttccccgccagccgg
cacggctcccccagccgctcggcccgagtaccccccttcaactatgtgcccagccccatg
gtggtcgcagccaccaccgactcggccgcggagaaagccccggccactgcctccgccacc
ctcctggaatag
Homo sapiens (human): 324
Help
Entry
324 CDS
T01001
Symbol
APC, BTPS2, DESMD, DP2, DP2.5, DP3, GS, PPP1R46
Name
(RefSeq) APC regulator of WNT signaling pathway
KO
K02085
adenomatosis polyposis coli protein
Organism
hsa
Homo sapiens (human)
Pathway
hsa04310
Wnt signaling pathway
hsa04390
Hippo signaling pathway
hsa04550
Signaling pathways regulating pluripotency of stem cells
hsa04810
Regulation of actin cytoskeleton
hsa04934
Cushing syndrome
hsa05010
Alzheimer disease
hsa05022
Pathways of neurodegeneration - multiple diseases
hsa05165
Human papillomavirus infection
hsa05200
Pathways in cancer
hsa05206
MicroRNAs in cancer
hsa05210
Colorectal cancer
hsa05213
Endometrial cancer
hsa05217
Basal cell carcinoma
hsa05224
Breast cancer
hsa05225
Hepatocellular carcinoma
hsa05226
Gastric cancer
Network
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06181
Salmonella
nt06215
WNT signaling (cancer)
nt06260
Colorectal cancer
nt06261
Gastric cancer
nt06263
Hepatocellular carcinoma
nt06270
Breast cancer
nt06271
Endometrial cancer
nt06274
Thyroid cancer
nt06505
WNT signaling
Element
N00056
Wnt signaling pathway
N00057
Mutation-inactivated APC to Wnt signaling pathway
N00058
Mutation-activated CTNNB1 to Wnt signaling pathway
N00059
FZD7-overexpression to Wnt signaling pathway
N00060
LRP6-overexpression to Wnt signaling pathway
N00242
Mutation-inactivated AXIN to Wnt signaling pathway
Disease
H00017
Esophageal cancer
H00018
Gastric cancer
H00020
Colorectal cancer
H00044
Cancer of the anal canal
H00047
Gallbladder cancer
H01025
Familial adenomatous polyposis
H01667
Medulloblastoma
H02049
Bilateral macronodular adrenal hyperplasia
H02302
Hepatoblastoma
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
324 (APC)
04390 Hippo signaling pathway
324 (APC)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
324 (APC)
09142 Cell motility
04810 Regulation of actin cytoskeleton
324 (APC)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
324 (APC)
05206 MicroRNAs in cancer
324 (APC)
09162 Cancer: specific types
05210 Colorectal cancer
324 (APC)
05225 Hepatocellular carcinoma
324 (APC)
05226 Gastric cancer
324 (APC)
05217 Basal cell carcinoma
324 (APC)
05213 Endometrial cancer
324 (APC)
05224 Breast cancer
324 (APC)
09172 Infectious disease: viral
05165 Human papillomavirus infection
324 (APC)
09164 Neurodegenerative disease
05010 Alzheimer disease
324 (APC)
05022 Pathways of neurodegeneration - multiple diseases
324 (APC)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
324 (APC)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
324 (APC)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
324 (APC)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
324 (APC)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
324 (APC)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centrosome formation proteins
Other centriole associated proteins
324 (APC)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
324 (APC)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_u14
APC_rep
APC_u15
APC_u9
APC_N_CC
SAMP
Arm
APC_u13
APC_15aa
Suppressor_APC
Sec7-like_HUS
Motif
Other DBs
NCBI-GeneID:
324
NCBI-ProteinID:
NP_000029
OMIM:
611731
HGNC:
583
Ensembl:
ENSG00000134982
UniProt:
P25054
Q4LE70
Structure
PDB
LinkDB
All DBs
Position
5:112707498..112846239
Genome browser
AA seq
2843 aa
AA seq
DB search
MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAM
ASSGQIDLLERLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPR
RGFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSL
QTDMTRRQLEYEARQIRVAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRIRQLLQSQAT
EAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGSTTRMDHETASVLSSSSTHSA
PRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLL
HGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC
WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQ
VDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDL
QQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCT
ENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENN
CLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAM
GSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLS
PKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS
LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTS
QEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSS
NDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGE
LDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTE
STDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKP
TNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKS
SSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ
TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPV
SEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET
PLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP
PPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGF
SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSE
KDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPS
QNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ
SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKP
FRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLN
AERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRND
SLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINR
GQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENN
NKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ
ECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD
WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFT
SNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQAN
MPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKS
ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPN
KLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKG
LNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESA
SFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG
RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSES
SEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAES
KTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDN
QAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERT
PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKT
DSTESSGTQSPKRHSGSYLVTSV
NT seq
8532 nt
NT seq
+upstream
nt +downstream
nt
atggctgcagcttcatatgatcagttgttaaagcaagttgaggcactgaagatggagaac
tcaaatcttcgacaagagctagaagataattccaatcatcttacaaaactggaaactgag
gcatctaatatgaaggaagtacttaaacaactacaaggaagtattgaagatgaagctatg
gcttcttctggacagattgatttattagagcgtcttaaagagcttaacttagatagcagt
aatttccctggagtaaaactgcggtcaaaaatgtccctccgttcttatggaagccgggaa
ggatctgtatcaagccgttctggagagtgcagtcctgttcctatgggttcatttccaaga
agagggtttgtaaatggaagcagagaaagtactggatatttagaagaacttgagaaagag
aggtcattgcttcttgctgatcttgacaaagaagaaaaggaaaaagactggtattacgct
caacttcagaatctcactaaaagaatagatagtcttcctttaactgaaaatttttcctta
caaacagatatgaccagaaggcaattggaatatgaagcaaggcaaatcagagttgcgatg
gaagaacaactaggtacctgccaggatatggaaaaacgagcacagcgaagaatagccaga
attcagcaaatcgaaaaggacatacttcgtatacgacagcttttacagtcccaagcaaca
gaagcagagaggtcatctcagaacaagcatgaaaccggctcacatgatgctgagcggcag
aatgaaggtcaaggagtgggagaaatcaacatggcaacttctggtaatggtcagggttca
actacacgaatggaccatgaaacagccagtgttttgagttctagtagcacacactctgca
cctcgaaggctgacaagtcatctgggaaccaaggtggaaatggtgtattcattgttgtca
atgcttggtactcatgataaggatgatatgtcgcgaactttgctagctatgtctagctcc
caagacagctgtatatccatgcgacagtctggatgtcttcctctcctcatccagctttta
catggcaatgacaaagactctgtattgttgggaaattcccggggcagtaaagaggctcgg
gccagggccagtgcagcactccacaacatcattcactcacagcctgatgacaagagaggc
aggcgtgaaatccgagtccttcatcttttggaacagatacgcgcttactgtgaaacctgt
tgggagtggcaggaagctcatgaaccaggcatggaccaggacaaaaatccaatgccagct
cctgttgaacatcagatctgtcctgctgtgtgtgttctaatgaaactttcatttgatgaa
gagcatagacatgcaatgaatgaactagggggactacaggccattgcagaattattgcaa
gtggactgtgaaatgtatgggcttactaatgaccactacagtattacactaagacgatat
gctggaatggctttgacaaacttgacttttggagatgtagccaacaaggctacgctatgc
tctatgaaaggctgcatgagagcacttgtggcccaactaaaatctgaaagtgaagactta
cagcaggttattgcgagtgttttgaggaatttgtcttggcgagcagatgtaaatagtaaa
aagacgttgcgagaagttggaagtgtgaaagcattgatggaatgtgctttagaagttaaa
aaggaatcaaccctcaaaagcgtattgagtgccttatggaatttgtcagcacattgcact
gagaataaagctgatatatgtgctgtagatggtgcacttgcatttttggttggcactctt
acttaccggagccagacaaacactttagccattattgaaagtggaggtgggatattacgg
aatgtgtccagcttgatagctacaaatgaggaccacaggcaaatcctaagagagaacaac
tgtctacaaactttattacaacacttaaaatctcatagtttgacaatagtcagtaatgca
tgtggaactttgtggaatctctcagcaagaaatcctaaagaccaggaagcattatgggac
atgggggcagttagcatgctcaagaacctcattcattcaaagcacaaaatgattgctatg
ggaagtgctgcagctttaaggaatctcatggcaaataggcctgcgaagtacaaggatgcc
aatattatgtctcctggctcaagcttgccatctcttcatgttaggaaacaaaaagcccta
gaagcagaattagatgctcagcacttatcagaaacttttgacaatatagacaatttaagt
cccaaggcatctcatcgtagtaagcagagacacaagcaaagtctctatggtgattatgtt
tttgacaccaatcgacatgatgataataggtcagacaattttaatactggcaacatgact
gtcctttcaccatatttgaatactacagtgttacccagctcctcttcatcaagaggaagc
ttagatagttctcgttctgaaaaagatagaagtttggagagagaacgcggaattggtcta
ggcaactaccatccagcaacagaaaatccaggaacttcttcaaagcgaggtttgcagatc
tccaccactgcagcccagattgccaaagtcatggaagaagtgtcagccattcatacctct
caggaagacagaagttctgggtctaccactgaattacattgtgtgacagatgagagaaat
gcacttagaagaagctctgctgcccatacacattcaaacacttacaatttcactaagtcg
gaaaattcaaataggacatgttctatgccttatgccaaattagaatacaagagatcttca
aatgatagtttaaatagtgtcagtagtagtgatggttatggtaaaagaggtcaaatgaaa
ccctcgattgaatcctattctgaagatgatgaaagtaagttttgcagttatggtcaatac
ccagccgacctagcccataaaatacatagtgcaaatcatatggatgataatgatggagaa
ctagatacaccaataaattatagtcttaaatattcagatgagcagttgaactctggaagg
caaagtccttcacagaatgaaagatgggcaagacccaaacacataatagaagatgaaata
aaacaaagtgagcaaagacaatcaaggaatcaaagtacaacttatcctgtttatactgag
agcactgatgataaacacctcaagttccaaccacattttggacagcaggaatgtgtttct
ccatacaggtcacggggagccaatggttcagaaacaaatcgagtgggttctaatcatgga
attaatcaaaatgtaagccagtctttgtgtcaagaagatgactatgaagatgataagcct
accaattatagtgaacgttactctgaagaagaacagcatgaagaagaagagagaccaaca
aattatagcataaaatataatgaagagaaacgtcatgtggatcagcctattgattatagt
ttaaaatatgccacagatattccttcatcacagaaacagtcattttcattctcaaagagt
tcatctggacaaagcagtaaaaccgaacatatgtcttcaagcagtgagaatacgtccaca
ccttcatctaatgccaagaggcagaatcagctccatccaagttctgcacagagtagaagt
ggtcagcctcaaaaggctgccacttgcaaagtttcttctattaaccaagaaacaatacag
acttattgtgtagaagatactccaatatgtttttcaagatgtagttcattatcatctttg
tcatcagctgaagatgaaataggatgtaatcagacgacacaggaagcagattctgctaat
accctgcaaatagcagaaataaaagaaaagattggaactaggtcagctgaagatcctgtg
agcgaagttccagcagtgtcacagcaccctagaaccaaatccagcagactgcagggttct
agtttatcttcagaatcagccaggcacaaagctgttgaattttcttcaggagcgaaatct
ccctccaaaagtggtgctcagacacccaaaagtccacctgaacactatgttcaggagacc
ccactcatgtttagcagatgtacttctgtcagttcacttgatagttttgagagtcgttcg
attgccagctccgttcagagtgaaccatgcagtggaatggtaagtggcattataagcccc
agtgatcttccagatagccctggacaaaccatgccaccaagcagaagtaaaacacctcca
ccacctcctcaaacagctcaaaccaagcgagaagtacctaaaaataaagcacctactgct
gaaaagagagagagtggacctaagcaagctgcagtaaatgctgcagttcagagggtccag
gttcttccagatgctgatactttattacattttgccacggaaagtactccagatggattt
tcttgttcatccagcctgagtgctctgagcctcgatgagccatttatacagaaagatgtg
gaattaagaataatgcctccagttcaggaaaatgacaatgggaatgaaacagaatcagag
cagcctaaagaatcaaatgaaaaccaagagaaagaggcagaaaaaactattgattctgaa
aaggacctattagatgattcagatgatgatgatattgaaatactagaagaatgtattatt
tctgccatgccaacaaagtcatcacgtaaagcaaaaaagccagcccagactgcttcaaaa
ttacctccacctgtggcaaggaaaccaagtcagctgcctgtgtacaaacttctaccatca
caaaacaggttgcaaccccaaaagcatgttagttttacaccgggggatgatatgccacgg
gtgtattgtgttgaagggacacctataaacttttccacagctacatctctaagtgatcta
acaatcgaatcccctccaaatgagttagctgctggagaaggagttagaggaggggcacag
tcaggtgaatttgaaaaacgagataccattcctacagaaggcagaagtacagatgaggct
caaggaggaaaaacctcatctgtaaccatacctgaattggatgacaataaagcagaggaa
ggtgatattcttgcagaatgcattaattctgctatgcccaaagggaaaagtcacaagcct
ttccgtgtgaaaaagataatggaccaggtccagcaagcatctgcgtcttcttctgcaccc
aacaaaaatcagttagatggtaagaaaaagaaaccaacttcaccagtaaaacctatacca
caaaatactgaatataggacacgtgtaagaaaaaatgcagactcaaaaaataatttaaat
gctgagagagttttctcagacaacaaagattcaaagaaacagaatttgaaaaataattcc
aaggtcttcaatgataagctcccaaataatgaagatagagtcagaggaagttttgctttt
gattcacctcatcattacacgcctattgaaggaactccttactgtttttcacgaaatgat
tctttgagttctctagattttgatgatgatgatgttgacctttccagggaaaaggctgaa
ttaagaaaggcaaaagaaaataaggaatcagaggctaaagttaccagccacacagaacta
acctccaaccaacaatcagctaataagacacaagctattgcaaagcagccaataaatcga
ggtcagcctaaacccatacttcagaaacaatccacttttccccagtcatccaaagacata
ccagacagaggggcagcaactgatgaaaagttacagaattttgctattgaaaatactccg
gtttgcttttctcataattcctctctgagttctctcagtgacattgaccaagaaaacaac
aataaagaaaatgaacctatcaaagagactgagccccctgactcacagggagaaccaagt
aaacctcaagcatcaggctatgctcctaaatcatttcatgttgaagataccccagtttgt
ttctcaagaaacagttctctcagttctcttagtattgactctgaagatgacctgttgcag
gaatgtataagctccgcaatgccaaaaaagaaaaagccttcaagactcaagggtgataat
gaaaaacatagtcccagaaatatgggtggcatattaggtgaagatctgacacttgatttg
aaagatatacagagaccagattcagaacatggtctatcccctgattcagaaaattttgat
tggaaagctattcaggaaggtgcaaattccatagtaagtagtttacatcaagctgctgct
gctgcatgtttatctagacaagcttcgtctgattcagattccatcctttccctgaaatca
ggaatctctctgggatcaccatttcatcttacacctgatcaagaagaaaaaccctttaca
agtaataaaggcccacgaattctaaaaccaggggagaaaagtacattggaaactaaaaag
atagaatctgaaagtaaaggaatcaaaggaggaaaaaaagtttataaaagtttgattact
ggaaaagttcgatctaattcagaaatttcaggccaaatgaaacagccccttcaagcaaac
atgccttcaatctctcgaggcaggacaatgattcatattccaggagttcgaaatagctcc
tcaagtacaagtcctgtttctaaaaaaggcccaccccttaagactccagcctccaaaagc
cctagtgaaggtcaaacagccaccacttctcctagaggagccaagccatctgtgaaatca
gaattaagccctgttgccaggcagacatcccaaataggtgggtcaagtaaagcaccttct
agatcaggatctagagattcgaccccttcaagacctgcccagcaaccattaagtagacct
atacagtctcctggccgaaactcaatttcccctggtagaaatggaataagtcctcctaac
aaattatctcaacttccaaggacatcatcccctagtactgcttcaactaagtcctcaggt
tctggaaaaatgtcatatacatctccaggtagacagatgagccaacagaaccttaccaaa
caaacaggtttatccaagaatgccagtagtattccaagaagtgagtctgcctccaaagga
ctaaatcagatgaataatggtaatggagccaataaaaaggtagaactttctagaatgtct
tcaactaaatcaagtggaagtgaatctgatagatcagaaagacctgtattagtacgccag
tcaactttcatcaaagaagctccaagcccaaccttaagaagaaaattggaggaatctgct
tcatttgaatctctttctccatcatctagaccagcttctcccactaggtcccaggcacaa
actccagttttaagtccttcccttcctgatatgtctctatccacacattcgtctgttcag
gctggtggatggcgaaaactcccacctaatctcagtcccactatagagtataatgatgga
agaccagcaaagcgccatgatattgcacggtctcattctgaaagtccttctagacttcca
atcaataggtcaggaacctggaaacgtgagcacagcaaacattcatcatcccttcctcga
gtaagcacttggagaagaactggaagttcatcttcaattctttctgcttcatcagaatcc
agtgaaaaagcaaaaagtgaggatgaaaaacatgtgaactctatttcaggaaccaaacaa
agtaaagaaaaccaagtatccgcaaaaggaacatggagaaaaataaaagaaaatgaattt
tctcccacaaatagtacttctcagaccgtttcctcaggtgctacaaatggtgctgaatca
aagactctaatttatcaaatggcacctgctgtttctaaaacagaggatgtttgggtgaga
attgaggactgtcccattaacaatcctagatctggaagatctcccacaggtaatactccc
ccggtgattgacagtgtttcagaaaaggcaaatccaaacattaaagattcaaaagataat
caggcaaaacaaaatgtgggtaatggcagtgttcccatgcgtaccgtgggtttggaaaat
cgcctgaactcctttattcaggtggatgcccctgaccaaaaaggaactgagataaaacca
ggacaaaataatcctgtccctgtatcagagactaatgaaagttctatagtggaacgtacc
ccattcagttctagcagctcaagcaaacacagttcacctagtgggactgttgctgccaga
gtgactccttttaattacaacccaagccctaggaaaagcagcgcagatagcacttcagct
cggccatctcagatcccaactccagtgaataacaacacaaagaagcgagattccaaaact
gacagcacagaatccagtggaacccaaagtcctaagcgccattctgggtcttaccttgtg
acatctgtttaa
DBGET
integrated database retrieval system
