KEGG   Homo sapiens (human): 10376
Entry
10376             CDS       T01001                                 
Symbol
TUBA1B, K-ALPHA-1
Name
(RefSeq) tubulin alpha-1B chain
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
nt06546  IgSF CAM signaling
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01285  Microtubule-RHOA signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01295  Rab7-regulated microtubule minus-end directed transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01403  Zn to anterograde axonal transport
N01414  Iron to anterograde axonal transport
N01535  Kinetochore microtubule attachment
N01544  Microtubule nucleation
N01547  Kinetochore fiber organization
N01549  Branching microtubule nucleation
N01553  Promotion of microtubule growth
N01561  Microtubule depolymerization
N01562  Microtubule depolymerization at the minus ends
N01832  NTN1-MAP1B axon guidance signaling
N01833  DRAXIN-MAP1B axon guidance signaling
N01834  SEMA3A-MAP1B axon guidance signaling
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01836  Microtubule plus end regulation network
N01837  Regulation of neurite extension, NAV1-TRIO
N01838  Regulation of synaptic plasticity, p140Cap
N01839  Severing of microtubule, SPAST/KATN
N01840  Severing of microtubule, KIF2A
N01841  Anterograde axonal transport, Kinesin-2
N01842  Anterograde axonal/dendrite transport, Kinesin-3
N01843  Anterograde dendrite transport, Kinesin-4
N01844  Anterograde dendrite transport, Kinesin-6
N01845  Anterograde axonal/dendrite transport, Kinesin-12
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
N01857  SEMA3A-DCX axon guidance signaling
N01858  EFNB1-MAPT axon guidance signaling
N01859  Anterograde axonal/dendrite transport, Kinesin-1
N01934  L1CAM interactions
N01939  Ganglioside-MAG signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    10376 (TUBA1B)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    10376 (TUBA1B)
  09143 Cell growth and death
   04210 Apoptosis
    10376 (TUBA1B)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10376 (TUBA1B)
   04540 Gap junction
    10376 (TUBA1B)
  09142 Cell motility
   04814 Motor proteins
    10376 (TUBA1B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10376 (TUBA1B)
   05132 Salmonella infection
    10376 (TUBA1B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    10376 (TUBA1B)
   05012 Parkinson disease
    10376 (TUBA1B)
   05014 Amyotrophic lateral sclerosis
    10376 (TUBA1B)
   05016 Huntington disease
    10376 (TUBA1B)
   05020 Prion disease
    10376 (TUBA1B)
   05022 Pathways of neurodegeneration - multiple diseases
    10376 (TUBA1B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    10376 (TUBA1B)
   03036 Chromosome and associated proteins [BR:hsa03036]
    10376 (TUBA1B)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10376 (TUBA1B)
   04147 Exosome [BR:hsa04147]
    10376 (TUBA1B)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     10376 (TUBA1B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     10376 (TUBA1B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    10376 (TUBA1B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   10376 (TUBA1B)
  Exosomal proteins of other body fluids (saliva and urine)
   10376 (TUBA1B)
  Exosomal proteins of colorectal cancer cells
   10376 (TUBA1B)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281
Other DBs
NCBI-GeneID: 10376
NCBI-ProteinID: NP_006073
OMIM: 602530
HGNC: 18809
Ensembl: ENSP00000336799.5
UniProt: P68363
Structure
LinkDB
Position
12:complement(49127782..49131395)
AA seq 451 aa
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
NT seq 1356 nt   +upstreamnt  +downstreamnt
atgcgtgagtgcatctccatccacgttggccaggctggtgtccagattggcaatgcctgc
tgggagctctactgcctggaacacggcatccagcccgatggccagatgccaagtgacaag
accattgggggaggagatgactccttcaacaccttcttcagtgagacgggcgctggcaag
cacgtgccccgggctgtgtttgtagacttggaacccacagtcattgatgaagttcgcact
ggcacctaccgccagctcttccaccctgagcagctcatcacaggcaaggaagatgctgcc
aataactatgcccgagggcactacaccattggcaaggagatcattgaccttgtgttggac
cgaattcgcaagctggctgaccagtgcaccggtcttcagggcttcttggttttccacagc
tttggtgggggaactggttctgggttcacctccctgctcatggaacgtctctcagttgat
tatggcaagaagtccaagctggagttctccatttacccagcaccccaggtttccacagct
gtagttgagccctacaactccatcctcaccacccacaccaccctggagcactctgattgt
gccttcatggtagacaatgaggccatctatgacatctgtcgtagaaacctcgatatcgag
cgcccaacctacactaaccttaaccgccttattagccagattgtgtcctccatcactgct
tccctgagatttgatggagccctgaatgttgacctgacagaattccagaccaacctggtg
ccctacccccgcatccacttccctctggccacatatgcccctgtcatctctgctgagaaa
gcctaccatgaacagctttctgtagcagagatcaccaatgcttgctttgagccagccaac
cagatggtgaaatgtgaccctcgccatggtaaatacatggcttgctgcctgttgtaccgt
ggtgacgtggttcccaaagatgtcaatgctgccattgccaccatcaaaaccaagcgcagc
atccagtttgtggattggtgccccactggcttcaaggttggcatcaactaccagcctccc
actgtggtgcctggtggagacctggccaaggtacagagagctgtgtgcatgctgagcaac
accacagccattgctgaggcctgggctcgcctggaccacaagtttgacctgatgtatgcc
aagcgtgcctttgttcactggtacgtgggtgaggggatggaggaaggcgagttttcagag
gcccgtgaagatatggctgcccttgagaaggattatgaggaggttggtgtggattctgtt
gaaggagagggtgaggaagaaggagaggaatactaa

KEGG   Homo sapiens (human): 112714
Entry
112714            CDS       T01001                                 
Symbol
TUBA3E
Name
(RefSeq) tubulin alpha-3E chain
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
nt06546  IgSF CAM signaling
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01285  Microtubule-RHOA signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01295  Rab7-regulated microtubule minus-end directed transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01403  Zn to anterograde axonal transport
N01414  Iron to anterograde axonal transport
N01535  Kinetochore microtubule attachment
N01544  Microtubule nucleation
N01547  Kinetochore fiber organization
N01549  Branching microtubule nucleation
N01553  Promotion of microtubule growth
N01561  Microtubule depolymerization
N01562  Microtubule depolymerization at the minus ends
N01832  NTN1-MAP1B axon guidance signaling
N01833  DRAXIN-MAP1B axon guidance signaling
N01834  SEMA3A-MAP1B axon guidance signaling
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01836  Microtubule plus end regulation network
N01837  Regulation of neurite extension, NAV1-TRIO
N01838  Regulation of synaptic plasticity, p140Cap
N01839  Severing of microtubule, SPAST/KATN
N01840  Severing of microtubule, KIF2A
N01841  Anterograde axonal transport, Kinesin-2
N01842  Anterograde axonal/dendrite transport, Kinesin-3
N01843  Anterograde dendrite transport, Kinesin-4
N01844  Anterograde dendrite transport, Kinesin-6
N01845  Anterograde axonal/dendrite transport, Kinesin-12
N01846  Retrograde axonal/dendrite transport, Dynein
N01857  SEMA3A-DCX axon guidance signaling
N01858  EFNB1-MAPT axon guidance signaling
N01859  Anterograde axonal/dendrite transport, Kinesin-1
N01934  L1CAM interactions
N01939  Ganglioside-MAG signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    112714 (TUBA3E)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    112714 (TUBA3E)
  09143 Cell growth and death
   04210 Apoptosis
    112714 (TUBA3E)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    112714 (TUBA3E)
   04540 Gap junction
    112714 (TUBA3E)
  09142 Cell motility
   04814 Motor proteins
    112714 (TUBA3E)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    112714 (TUBA3E)
   05132 Salmonella infection
    112714 (TUBA3E)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    112714 (TUBA3E)
   05012 Parkinson disease
    112714 (TUBA3E)
   05014 Amyotrophic lateral sclerosis
    112714 (TUBA3E)
   05016 Huntington disease
    112714 (TUBA3E)
   05020 Prion disease
    112714 (TUBA3E)
   05022 Pathways of neurodegeneration - multiple diseases
    112714 (TUBA3E)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    112714 (TUBA3E)
   03036 Chromosome and associated proteins [BR:hsa03036]
    112714 (TUBA3E)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    112714 (TUBA3E)
   04147 Exosome [BR:hsa04147]
    112714 (TUBA3E)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     112714 (TUBA3E)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     112714 (TUBA3E)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    112714 (TUBA3E)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   112714 (TUBA3E)
  Exosomal proteins of other body fluids (saliva and urine)
   112714 (TUBA3E)
  Exosomal proteins of colorectal cancer cells
   112714 (TUBA3E)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281 DUF8666
Other DBs
NCBI-GeneID: 112714
NCBI-ProteinID: NP_997195
OMIM: 619918
HGNC: 20765
Ensembl: ENSP00000318197.7
UniProt: Q6PEY2 A0AAG2UW83
LinkDB
Position
2:complement(130191745..130198439)
AA seq 450 aa
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARGHYTIGKEIVDLVLD
RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSKLEFAIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLVHKFDLMYAKWAFVHWYVGEGMEEGEFSE
AREDLAALEKDCEEVGVDSVEAEAEEGEAY
NT seq 1353 nt   +upstreamnt  +downstreamnt
atgcgcgagtgtatctctatccacgtggggcaggcgggtgtccagatcggcaatgcctgc
tgggaactgtactgccttgaacatggaattcagcccgatggtcaaatgccaagtgataaa
accattggtggcggggacgactccttcaacacgttcttcagtgagactggagctggcaag
cacgtgcccagagcagtgtttgtggacctggagcccactgtggtcgatgaagtgcgcaca
gggacctacaggcagctcttccacccagagcagctgatcaccgggaaggaagatgcagcc
agtaattacgccaggggccattacaccatcggcaaggagattgttgacctagtcctggac
cggatccgcaaactggcggatctgtgcacaggactgcagggcttcctcatcttccacagc
tttgggggcggcactggctctgggttcgcatctctgctcatggagcggctctcagtggat
tacagcaagaagtccaagctagagtttgccatttacccagccccccaggtctccacagcc
gtggtggagccctacaactccatcctaaccacccacacgaccctggaacattctgactgt
gccttcatggtcgacaatgaagccatctatgacatatgtcggcgcaacctggacattgaa
cgtcccacgtacaccaacctcaatcgcctgattgggcagatcgtgtcctccatcacggcc
tccctgcgatttgatggggccctgaatgtggacttgacggaattccagaccaacctcgtg
ccgtacccccgcatccacttccccctggccacctacgccccagtcatctcagctgagaag
gcctaccacgagcagctgtctgtggccgagatcaccaatgcctgcttcgagccagccaat
cagatggtcaagtgtgaccctcgccatggcaagtacatggcctgctgcatgttgtacagg
ggggacgtggtccccaaagacgtcaatgcggccatcgccaccatcaagaccaagcgcact
atccagtttgtggattggtgcccgactggatttaaggtgggcattaactaccagcccccc
acagtggtccccgggggagacctggccaaggtgcagcgggccgtgtgcatgctgagcaac
accacggccattgcggaggcctgggcccgcctggtccataagttcgatctcatgtatgcc
aagtgggcctttgtgcactggtacgtgggcgaaggcatggaagagggagagttctctgag
gcccgcgaggacctggcagctctagagaaggattgtgaagaggtgggcgtggattccgtg
gaagctgaggctgaagaaggcgaagcatactga

KEGG   Homo sapiens (human): 113457
Entry
113457            CDS       T01001                                 
Symbol
TUBA3D, H2-ALPHA, KTCN9, TUBA2
Name
(RefSeq) tubulin alpha-3D chain
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
nt06546  IgSF CAM signaling
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01285  Microtubule-RHOA signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01295  Rab7-regulated microtubule minus-end directed transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01403  Zn to anterograde axonal transport
N01414  Iron to anterograde axonal transport
N01535  Kinetochore microtubule attachment
N01544  Microtubule nucleation
N01547  Kinetochore fiber organization
N01549  Branching microtubule nucleation
N01553  Promotion of microtubule growth
N01561  Microtubule depolymerization
N01562  Microtubule depolymerization at the minus ends
N01832  NTN1-MAP1B axon guidance signaling
N01833  DRAXIN-MAP1B axon guidance signaling
N01834  SEMA3A-MAP1B axon guidance signaling
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01836  Microtubule plus end regulation network
N01837  Regulation of neurite extension, NAV1-TRIO
N01838  Regulation of synaptic plasticity, p140Cap
N01839  Severing of microtubule, SPAST/KATN
N01840  Severing of microtubule, KIF2A
N01841  Anterograde axonal transport, Kinesin-2
N01842  Anterograde axonal/dendrite transport, Kinesin-3
N01843  Anterograde dendrite transport, Kinesin-4
N01844  Anterograde dendrite transport, Kinesin-6
N01845  Anterograde axonal/dendrite transport, Kinesin-12
N01846  Retrograde axonal/dendrite transport, Dynein
N01857  SEMA3A-DCX axon guidance signaling
N01858  EFNB1-MAPT axon guidance signaling
N01859  Anterograde axonal/dendrite transport, Kinesin-1
N01934  L1CAM interactions
N01939  Ganglioside-MAG signaling
Disease
H00789  Keratoconus
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    113457 (TUBA3D)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    113457 (TUBA3D)
  09143 Cell growth and death
   04210 Apoptosis
    113457 (TUBA3D)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    113457 (TUBA3D)
   04540 Gap junction
    113457 (TUBA3D)
  09142 Cell motility
   04814 Motor proteins
    113457 (TUBA3D)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    113457 (TUBA3D)
   05132 Salmonella infection
    113457 (TUBA3D)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    113457 (TUBA3D)
   05012 Parkinson disease
    113457 (TUBA3D)
   05014 Amyotrophic lateral sclerosis
    113457 (TUBA3D)
   05016 Huntington disease
    113457 (TUBA3D)
   05020 Prion disease
    113457 (TUBA3D)
   05022 Pathways of neurodegeneration - multiple diseases
    113457 (TUBA3D)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    113457 (TUBA3D)
   03036 Chromosome and associated proteins [BR:hsa03036]
    113457 (TUBA3D)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    113457 (TUBA3D)
   04147 Exosome [BR:hsa04147]
    113457 (TUBA3D)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     113457 (TUBA3D)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     113457 (TUBA3D)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    113457 (TUBA3D)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   113457 (TUBA3D)
  Exosomal proteins of other body fluids (saliva and urine)
   113457 (TUBA3D)
  Exosomal proteins of colorectal cancer cells
   113457 (TUBA3D)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281 DUF8666
Other DBs
NCBI-GeneID: 113457
NCBI-ProteinID: NP_525125
OMIM: 617878
HGNC: 24071
Ensembl: ENSP00000326042.6
UniProt: P0DPH7 P0DPH8 Q1ZYQ1
LinkDB
Position
2:131476119..131482934
AA seq 450 aa
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDLAALEKDYEEVGVDSVEAEAEEGEEY
NT seq 1353 nt   +upstreamnt  +downstreamnt
atgcgcgagtgtatctctatccacgtggggcaggcgggtgtccagatcggcaatgcctgc
tgggaactgtactgccttgaacatggaattcagcccgatggccaaatgccaagtgataaa
accattggtggcggggacgactccttcaacacgttcttcagtgagactggagctggcaag
cacgtgcccagagcagtgtttgtggacctggagcccactgtggtcgatgaagtgcgcaca
gggacctacaggcagctcttccacccggagcagctgatcaccgggaaggaagatgcagcc
aataattacgccaggggccattacaccatcggcaaggagattgttgacctagtcctggac
cggatccgcaaactggcggatctgtgcacaggactgcagggcttcctcatcttccacagc
tttgggggcggcactggctctgggttcgcatctctgctcatggagcggctctcagtggat
tacggcaagaagtccaagctagagtttgccatttacccagccccccaggtctccacagcc
gtggtggagccctacaactccatcctgaccacccacacgaccctggaacattctgactgt
gccttcatggtcgacaatgaagccatctatgacatatgtcggcgcaacctggacattgaa
cgtcccacgtacaccaacctcaatcgcctgattgggcagatcgtgtcctccatcacagcc
tccctgcgatttgatggggccctgaatgtggacttgacggaattccagaccaacctagtg
ccgtacccccgcatccacttccccctggccacctatgccccagtcatctcagctgagaag
gcctaccacgagcagctgtctgtggccgagatcaccaatgcctgcttcgagccagccaat
caaatggtcaagtgtgaccctcgccacggcaagtacatggcctgctgcatgttgtacagg
ggggacgtggtccccaaagacgtcaacgcggccatcgccaccatcaagaccaagcgcacc
atccagtttgtggattggtgcccgactggatttaaggtgggcattaactaccagcccccc
acagtggtccccgggggagacctggccaaggtgcagcgggccgtgtgcatgctgagcaac
accacggccattgcggaggcctgggcccgcctggaccataagttcgatctcatgtatgcc
aagcgggcctttgtgcactggtacgtgggcgaaggcatggaagagggagagttctctgag
gcccgcgaggacctggcagctctagagaaggattatgaagaggtgggcgtggattccgtg
gaagctgaggctgaagaaggcgaagaatactga

KEGG   Homo sapiens (human): 51807
Entry
51807             CDS       T01001                                 
Symbol
TUBA8, CDCBM8, MACTHC2, TUBAL2
Name
(RefSeq) tubulin alpha-8 chain isoform 1
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
nt06546  IgSF CAM signaling
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01285  Microtubule-RHOA signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01295  Rab7-regulated microtubule minus-end directed transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01403  Zn to anterograde axonal transport
N01414  Iron to anterograde axonal transport
N01535  Kinetochore microtubule attachment
N01544  Microtubule nucleation
N01547  Kinetochore fiber organization
N01549  Branching microtubule nucleation
N01553  Promotion of microtubule growth
N01561  Microtubule depolymerization
N01562  Microtubule depolymerization at the minus ends
N01832  NTN1-MAP1B axon guidance signaling
N01833  DRAXIN-MAP1B axon guidance signaling
N01834  SEMA3A-MAP1B axon guidance signaling
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01836  Microtubule plus end regulation network
N01837  Regulation of neurite extension, NAV1-TRIO
N01838  Regulation of synaptic plasticity, p140Cap
N01839  Severing of microtubule, SPAST/KATN
N01840  Severing of microtubule, KIF2A
N01841  Anterograde axonal transport, Kinesin-2
N01842  Anterograde axonal/dendrite transport, Kinesin-3
N01843  Anterograde dendrite transport, Kinesin-4
N01844  Anterograde dendrite transport, Kinesin-6
N01845  Anterograde axonal/dendrite transport, Kinesin-12
N01846  Retrograde axonal/dendrite transport, Dynein
N01857  SEMA3A-DCX axon guidance signaling
N01858  EFNB1-MAPT axon guidance signaling
N01859  Anterograde axonal/dendrite transport, Kinesin-1
N01934  L1CAM interactions
N01939  Ganglioside-MAG signaling
Disease
H01740  Macrothrombocytopenia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    51807 (TUBA8)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    51807 (TUBA8)
  09143 Cell growth and death
   04210 Apoptosis
    51807 (TUBA8)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    51807 (TUBA8)
   04540 Gap junction
    51807 (TUBA8)
  09142 Cell motility
   04814 Motor proteins
    51807 (TUBA8)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    51807 (TUBA8)
   05132 Salmonella infection
    51807 (TUBA8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    51807 (TUBA8)
   05012 Parkinson disease
    51807 (TUBA8)
   05014 Amyotrophic lateral sclerosis
    51807 (TUBA8)
   05016 Huntington disease
    51807 (TUBA8)
   05020 Prion disease
    51807 (TUBA8)
   05022 Pathways of neurodegeneration - multiple diseases
    51807 (TUBA8)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    51807 (TUBA8)
   03036 Chromosome and associated proteins [BR:hsa03036]
    51807 (TUBA8)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    51807 (TUBA8)
   04147 Exosome [BR:hsa04147]
    51807 (TUBA8)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     51807 (TUBA8)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     51807 (TUBA8)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    51807 (TUBA8)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   51807 (TUBA8)
  Exosomal proteins of other body fluids (saliva and urine)
   51807 (TUBA8)
  Exosomal proteins of colorectal cancer cells
   51807 (TUBA8)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281 DUF8666
Other DBs
NCBI-GeneID: 51807
NCBI-ProteinID: NP_061816
OMIM: 605742
HGNC: 12410
Ensembl: ENSP00000333326.3
UniProt: Q9NY65
LinkDB
Position
22:18110809..18131732
AA seq 449 aa
MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK
HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD
RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS
QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDLAALEKDYEEVGTDSFEEENEGEEF
NT seq 1350 nt   +upstreamnt  +downstreamnt
atgcgggaatgcatatcagtccacgtgggccaagcgggagttcagattggcaatgcctgc
tgggagctcttctgcctggaacacggcatccaggcagacggcacttttgatgctcaagct
agcaagatcaacgatgatgactccttcaccacctttttcagcgagactggcaatgggaag
catgtgccccgggccgtcatgatagatctggagcctactgtagtggatgaggttcgggca
ggaacctaccgccagctcttccatccagagcagctgatcacaggaaaggaggatgcagcc
aacaactatgcccggggccactacacggtgggcaaggagagcattgacctggtgctggac
cgcatacggaagctgacagatgcttgctctggcctgcagggcttcctgattttccacagt
tttggtgggggcactggctccggcttcacttctctgctgatggaacgcctctccctggat
tatggcaagaaatccaagctggagtttgccatctacccagccccccaggtctctactgca
gtggtggagccctacaactccatcctgaccacccacaccacactggaacattcagattgt
gctttcatggtggacaacgaagccatctatgacatctgccgcaggaaccttgacattgag
cgccctacctataccaacctcaaccgcctcatcagtcagattgtgtcctcaatcactgct
tctctccgctttgacggggccctcaatgtggacctcactgagttccagaccaacctggtg
ccctacccccgcatccacttcccgctggtcacctacgcgcccatcatctctgccgagaaa
gcctatcacgaacagctctctgtggccgagataaccagctcctgctttgagcccaacagc
cagatggtgaagtgcgacccgagacatggcaagtacatggcctgctgcatgctctaccgg
ggcgacgtggtgcccaaggatgtgaatgtcgctattgctgccatcaagaccaagaggacc
atccagtttgtagactggtgtcccacaggcttcaaggtgggcatcaactaccagcccccg
accgtggtccccgggggagacctggccaaggtgcagcgggccgtctgcatgctcagcaac
accacggccattgcggaggcctgggcccgcctcgaccacaagttcgacctcatgtacgcc
aagcgggcctttgtgcattggtatgtgggagaggggatggaagaaggagaattttctgag
gccagggaagacttagctgccctggagaaggattatgaagaagtggggactgattcgttt
gaagaagaaaatgaaggggaggaattttaa

KEGG   Homo sapiens (human): 7277
Entry
7277              CDS       T01001                                 
Symbol
TUBA4A, ALS22, CMYO26, FTDALS9, H2-ALPHA, OZEMA23, SPAX11, TUBA1
Name
(RefSeq) tubulin alpha-4A chain isoform 1
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
nt06546  IgSF CAM signaling
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01159  Mutation-caused aberrant TUBA4A to retrograde axonal transport
N01285  Microtubule-RHOA signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01295  Rab7-regulated microtubule minus-end directed transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01403  Zn to anterograde axonal transport
N01414  Iron to anterograde axonal transport
N01535  Kinetochore microtubule attachment
N01544  Microtubule nucleation
N01547  Kinetochore fiber organization
N01549  Branching microtubule nucleation
N01553  Promotion of microtubule growth
N01561  Microtubule depolymerization
N01562  Microtubule depolymerization at the minus ends
N01832  NTN1-MAP1B axon guidance signaling
N01833  DRAXIN-MAP1B axon guidance signaling
N01834  SEMA3A-MAP1B axon guidance signaling
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01836  Microtubule plus end regulation network
N01837  Regulation of neurite extension, NAV1-TRIO
N01838  Regulation of synaptic plasticity, p140Cap
N01839  Severing of microtubule, SPAST/KATN
N01840  Severing of microtubule, KIF2A
N01841  Anterograde axonal transport, Kinesin-2
N01842  Anterograde axonal/dendrite transport, Kinesin-3
N01843  Anterograde dendrite transport, Kinesin-4
N01844  Anterograde dendrite transport, Kinesin-6
N01845  Anterograde axonal/dendrite transport, Kinesin-12
N01846  Retrograde axonal/dendrite transport, Dynein
N01857  SEMA3A-DCX axon guidance signaling
N01858  EFNB1-MAPT axon guidance signaling
N01859  Anterograde axonal/dendrite transport, Kinesin-1
N01934  L1CAM interactions
N01939  Ganglioside-MAG signaling
Disease
H01351  Spastic ataxia
H01810  Congenital myopathy
H01897  Oocyte/zygote/embryo maturation arrest
H02342  Frontotemporal dementia and amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    7277 (TUBA4A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    7277 (TUBA4A)
  09143 Cell growth and death
   04210 Apoptosis
    7277 (TUBA4A)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    7277 (TUBA4A)
   04540 Gap junction
    7277 (TUBA4A)
  09142 Cell motility
   04814 Motor proteins
    7277 (TUBA4A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    7277 (TUBA4A)
   05132 Salmonella infection
    7277 (TUBA4A)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    7277 (TUBA4A)
   05012 Parkinson disease
    7277 (TUBA4A)
   05014 Amyotrophic lateral sclerosis
    7277 (TUBA4A)
   05016 Huntington disease
    7277 (TUBA4A)
   05020 Prion disease
    7277 (TUBA4A)
   05022 Pathways of neurodegeneration - multiple diseases
    7277 (TUBA4A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    7277 (TUBA4A)
   03036 Chromosome and associated proteins [BR:hsa03036]
    7277 (TUBA4A)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    7277 (TUBA4A)
   04147 Exosome [BR:hsa04147]
    7277 (TUBA4A)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     7277 (TUBA4A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     7277 (TUBA4A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    7277 (TUBA4A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   7277 (TUBA4A)
  Exosomal proteins of other body fluids (saliva and urine)
   7277 (TUBA4A)
  Exosomal proteins of colorectal cancer cells
   7277 (TUBA4A)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281
Other DBs
NCBI-GeneID: 7277
NCBI-ProteinID: NP_005991
OMIM: 191110
HGNC: 12407
Ensembl: ENSP00000248437.4
UniProt: P68366
LinkDB
Position
2:complement(219249710..219254740)
AA seq 448 aa
MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK
HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD
RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGIDSYEDEDEGEE
NT seq 1347 nt   +upstreamnt  +downstreamnt
atgcgtgaatgcatctcagtccacgtggggcaggcaggtgtccagatgggcaatgcctgc
tgggagctctattgcttggaacatgggattcagcctgatgggcagatgcccagtgacaag
accattggtggaggggacgactccttcaccaccttcttctgtgaaactggtgctggaaaa
cacgtaccccgggcagtttttgtggatctggagcctacggtcattgatgagatccgaaat
ggcccataccgacagctcttccacccagagcagctcatcactgggaaagaggatgctgcc
aacaactatgcccgtggtcactataccattggcaaggagatcattgacccagtgctggat
cggatccgcaagctgtctgaccagtgcacaggacttcagggcttcctggtgttccacagc
tttggtgggggcactggctctggcttcacctcactcctgatggagcggctctctgttgac
tatggcaagaaatccaagctggaattctccatctacccagccccccaggtgtctacagcc
gtggtcgagccctacaactctatcctgaccacccacaccaccctggagcactcagactgt
gccttcatggtggacaacgaagcaatctatgacatctgccgccgcaacctagacatcgag
cgcccaacctacaccaacctcaatcgcctcattagccaaattgtctcctccatcacagct
tctctgcgctttgacggggccctcaatgtggacctgacagagttccagaccaacctggtg
ccctaccctcgcatccacttccccctggccacctatgcaccagtcatctctgcagaaaag
gcataccacgagcagctgtcggtggcagagatcaccaatgcctgctttgagcctgccaac
cagatggtaaagtgtgatccccggcacggcaagtacatggcctgctgcctgctgtaccgt
ggagatgtggtgcccaaggatgtcaacgctgccattgccgccatcaagaccaagcgcagc
attcagtttgtggactggtgccccacaggcttcaaggttggtatcaactaccagcctccc
actgtggtgcctgggggtgacctggccaaggtgcagcgtgccgtgtgcatgctgagcaac
acgaccgccatcgccgaggcctgggcccgcctggaccacaagttcgacctgatgtatgcc
aagagggcgtttgtgcactggtatgtgggtgagggcatggaggagggtgagttctccgag
gcccgtgaggatatggctgccctggagaaggattatgaggaggtgggcatcgactcctat
gaggacgaggatgagggagaagaataa

KEGG   Homo sapiens (human): 7278
Entry
7278              CDS       T01001                                 
Symbol
TUBA3C, TUBA2, bA408E5.3
Name
(RefSeq) tubulin alpha-3C chain
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
nt06546  IgSF CAM signaling
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01285  Microtubule-RHOA signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01295  Rab7-regulated microtubule minus-end directed transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01403  Zn to anterograde axonal transport
N01414  Iron to anterograde axonal transport
N01535  Kinetochore microtubule attachment
N01544  Microtubule nucleation
N01547  Kinetochore fiber organization
N01549  Branching microtubule nucleation
N01553  Promotion of microtubule growth
N01561  Microtubule depolymerization
N01562  Microtubule depolymerization at the minus ends
N01832  NTN1-MAP1B axon guidance signaling
N01833  DRAXIN-MAP1B axon guidance signaling
N01834  SEMA3A-MAP1B axon guidance signaling
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01836  Microtubule plus end regulation network
N01837  Regulation of neurite extension, NAV1-TRIO
N01838  Regulation of synaptic plasticity, p140Cap
N01839  Severing of microtubule, SPAST/KATN
N01840  Severing of microtubule, KIF2A
N01841  Anterograde axonal transport, Kinesin-2
N01842  Anterograde axonal/dendrite transport, Kinesin-3
N01843  Anterograde dendrite transport, Kinesin-4
N01844  Anterograde dendrite transport, Kinesin-6
N01845  Anterograde axonal/dendrite transport, Kinesin-12
N01846  Retrograde axonal/dendrite transport, Dynein
N01857  SEMA3A-DCX axon guidance signaling
N01858  EFNB1-MAPT axon guidance signaling
N01859  Anterograde axonal/dendrite transport, Kinesin-1
N01934  L1CAM interactions
N01939  Ganglioside-MAG signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    7278 (TUBA3C)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    7278 (TUBA3C)
  09143 Cell growth and death
   04210 Apoptosis
    7278 (TUBA3C)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    7278 (TUBA3C)
   04540 Gap junction
    7278 (TUBA3C)
  09142 Cell motility
   04814 Motor proteins
    7278 (TUBA3C)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    7278 (TUBA3C)
   05132 Salmonella infection
    7278 (TUBA3C)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    7278 (TUBA3C)
   05012 Parkinson disease
    7278 (TUBA3C)
   05014 Amyotrophic lateral sclerosis
    7278 (TUBA3C)
   05016 Huntington disease
    7278 (TUBA3C)
   05020 Prion disease
    7278 (TUBA3C)
   05022 Pathways of neurodegeneration - multiple diseases
    7278 (TUBA3C)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    7278 (TUBA3C)
   03036 Chromosome and associated proteins [BR:hsa03036]
    7278 (TUBA3C)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    7278 (TUBA3C)
   04147 Exosome [BR:hsa04147]
    7278 (TUBA3C)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     7278 (TUBA3C)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     7278 (TUBA3C)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    7278 (TUBA3C)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   7278 (TUBA3C)
  Exosomal proteins of other body fluids (saliva and urine)
   7278 (TUBA3C)
  Exosomal proteins of colorectal cancer cells
   7278 (TUBA3C)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281 DUF8666
Other DBs
NCBI-GeneID: 7278
NCBI-ProteinID: NP_005992
OMIM: 602528
HGNC: 12408
Ensembl: ENSP00000382982.3
UniProt: P0DPH7 P0DPH8 Q1ZYQ1
LinkDB
Position
13:complement(19173772..19181824)
AA seq 450 aa
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD
RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDLAALEKDYEEVGVDSVEAEAEEGEEY
NT seq 1353 nt   +upstreamnt  +downstreamnt
atgcgtgagtgtatctctatccacgtggggcaggcaggagtccagatcggcaatgcctgc
tgggaactgtactgcctggaacatggaattcagcccgatggtcagatgccaagtgataaa
accattggtggtggggacgactccttcaacacgttcttcagtgagactggagctggcaag
cacgtgcccagagcagtgtttgtggacctggagcccactgtggtcgatgaagtgcgcaca
ggaacctataggcagctcttccacccagagcagctgatcaccgggaaggaagatgcggcc
aataattacgccagaggccattacaccatcggcaaggagatcgtcgacctggtcctggac
cggatccgcaaactggcggatctgtgcacgggactgcagggcttcctcatcttccacagt
tttgggggtggcactggctctgggttcgcatctctgctcatggagcggctctcagtggat
tacggcaagaagtccaagctagaatttgccatttacccagccccccaggtctccacggcc
gtggtggagccctacaactccatcctgaccacccacacgaccctggaacattctgactgt
gccttcatggtcgacaatgaagccatctatgacatatgtcggcgcaacctggacatcgag
cgtcccacgtacaccaacctcaatcgcctgattgggcagatcgtgtcctccatcacggcc
tccctgcgatttgacggggccctgaatgtggacttgacggaattccagaccaacctagtg
ccgtacccccgcatccacttccccctggccacctacgccccggtcatctcagccgagaag
gcctaccacgagcagctgtccgtggctgagatcaccaatgcctgcttcgagccagccaat
cagatggtcaagtgtgaccctcgccacggcaagtacatggcctgctgcatgttgtacagg
ggggatgtggtcccgaaagatgtcaacgcggccatcgccaccatcaagaccaagcgcacc
atccagtttgtagattggtgcccaactggatttaaggtgggcattaactaccagcccccc
acggtggtccctgggggagacctggccaaggtgcagcgggctgtgtgcatgctgagcaac
accacggccatcgcggaggcctgggctcgcctggaccataagttcgatctcatgtatgcc
aagcgggcctttgtgcactggtacgtgggagaaggcatggaggagggggagttctctgag
gcccgcgaggacctggcagctctggagaaggattatgaagaggtgggcgtggattccgtg
gaagccgaggctgaagaaggtgaagaatactga

KEGG   Homo sapiens (human): 7846
Entry
7846              CDS       T01001                                 
Symbol
TUBA1A, B-ALPHA-1, LIS3, TUBA3
Name
(RefSeq) tubulin alpha-1A chain isoform 1
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
nt06546  IgSF CAM signaling
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01285  Microtubule-RHOA signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01295  Rab7-regulated microtubule minus-end directed transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01403  Zn to anterograde axonal transport
N01414  Iron to anterograde axonal transport
N01535  Kinetochore microtubule attachment
N01544  Microtubule nucleation
N01547  Kinetochore fiber organization
N01549  Branching microtubule nucleation
N01553  Promotion of microtubule growth
N01561  Microtubule depolymerization
N01562  Microtubule depolymerization at the minus ends
N01832  NTN1-MAP1B axon guidance signaling
N01833  DRAXIN-MAP1B axon guidance signaling
N01834  SEMA3A-MAP1B axon guidance signaling
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01836  Microtubule plus end regulation network
N01837  Regulation of neurite extension, NAV1-TRIO
N01838  Regulation of synaptic plasticity, p140Cap
N01839  Severing of microtubule, SPAST/KATN
N01840  Severing of microtubule, KIF2A
N01841  Anterograde axonal transport, Kinesin-2
N01842  Anterograde axonal/dendrite transport, Kinesin-3
N01843  Anterograde dendrite transport, Kinesin-4
N01844  Anterograde dendrite transport, Kinesin-6
N01845  Anterograde axonal/dendrite transport, Kinesin-12
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
N01857  SEMA3A-DCX axon guidance signaling
N01858  EFNB1-MAPT axon guidance signaling
N01859  Anterograde axonal/dendrite transport, Kinesin-1
N01934  L1CAM interactions
N01939  Ganglioside-MAG signaling
Disease
H01881  Complex cortical dysplasia with other brain malformations
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    7846 (TUBA1A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    7846 (TUBA1A)
  09143 Cell growth and death
   04210 Apoptosis
    7846 (TUBA1A)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    7846 (TUBA1A)
   04540 Gap junction
    7846 (TUBA1A)
  09142 Cell motility
   04814 Motor proteins
    7846 (TUBA1A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    7846 (TUBA1A)
   05132 Salmonella infection
    7846 (TUBA1A)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    7846 (TUBA1A)
   05012 Parkinson disease
    7846 (TUBA1A)
   05014 Amyotrophic lateral sclerosis
    7846 (TUBA1A)
   05016 Huntington disease
    7846 (TUBA1A)
   05020 Prion disease
    7846 (TUBA1A)
   05022 Pathways of neurodegeneration - multiple diseases
    7846 (TUBA1A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    7846 (TUBA1A)
   03036 Chromosome and associated proteins [BR:hsa03036]
    7846 (TUBA1A)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    7846 (TUBA1A)
   04147 Exosome [BR:hsa04147]
    7846 (TUBA1A)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     7846 (TUBA1A)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     7846 (TUBA1A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    7846 (TUBA1A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   7846 (TUBA1A)
  Exosomal proteins of other body fluids (saliva and urine)
   7846 (TUBA1A)
  Exosomal proteins of colorectal cancer cells
   7846 (TUBA1A)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281
Other DBs
NCBI-GeneID: 7846
NCBI-ProteinID: NP_001257328
OMIM: 602529
HGNC: 20766
UniProt: Q71U36
Structure
LinkDB
Position
12:complement(49184795..49189080)
AA seq 451 aa
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGVDSVEGEGEEEGEEY
NT seq 1356 nt   +upstreamnt  +downstreamnt
atgcgtgagtgcatctccatccacgttggccaggctggtgtccagattggcaatgcctgc
tgggagctctactgcctggaacacggcatccagcccgatggccagatgccaagtgacaag
accattgggggaggagatgattccttcaacaccttcttcagtgagacgggggctggcaag
catgtgccccgggcagtgtttgtagacttggaacccacagtcattgatgaagttcgcact
ggcacctaccgccagctcttccaccctgagcaacttatcacaggcaaagaagatgctgcc
aataactatgcccgagggcactacaccattggcaaggagatcattgacctcgtgttggac
cgaattcgcaagctggccgaccagtgcacgggtctccagggcttcttggttttccacagc
tttggtgggggaactggttctgggttcacctcgctgctcatggaacgtctctcagttgat
tatggcaagaagtccaagctggagttctctatttacccggcgccccaggtttccacagct
gtagttgagccctacaactccatcctcaccacccacaccaccctggagcactctgattgt
gccttcatggtagacaatgaggccatctatgacatctgtcgtagaaacctcgatattgag
cgtccaacctatactaacctgaataggttaataggtcaaattgtgtcctccatcactgct
tccctgagatttgatggagccctgaatgttgacctgacagaattccagaccaacctggtg
ccctatccccgcatccacttccctctggccacatatgcccctgtcatctctgctgagaaa
gcctaccatgaacagctttctgtagcagagatcaccaatgcttgctttgagccagccaac
cagatggtgaaatgtgaccctcgccatggtaaatacatggcttgctgcctgttgtaccgt
ggtgacgtggttcccaaagatgtcaatgctgccattgccaccatcaagaccaagcgtacc
atccagtttgtggattggtgccccactggcttcaaggttggcatcaactaccagcctccc
actgtggtgcctggtggagacctggccaaggtacagagagctgtgtgcatgctgagcaac
accacagccattgctgaggcctgggctcgcctggaccacaagtttgacctgatgtatgcc
aaacgtgcctttgttcactggtacgttggggaggggatggaggaaggtgagttttcagag
gcccgtgaggacatggctgcccttgagaaggattatgaggaggttggtgtggattctgtt
gaaggagagggtgaggaagaaggagaggaatactaa

KEGG   Homo sapiens (human): 79861
Entry
79861             CDS       T01001                                 
Symbol
TUBAL3
Name
(RefSeq) tubulin alpha chain-like 3 isoform 1
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    79861 (TUBAL3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    79861 (TUBAL3)
  09143 Cell growth and death
   04210 Apoptosis
    79861 (TUBAL3)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    79861 (TUBAL3)
   04540 Gap junction
    79861 (TUBAL3)
  09142 Cell motility
   04814 Motor proteins
    79861 (TUBAL3)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    79861 (TUBAL3)
   05132 Salmonella infection
    79861 (TUBAL3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    79861 (TUBAL3)
   05012 Parkinson disease
    79861 (TUBAL3)
   05014 Amyotrophic lateral sclerosis
    79861 (TUBAL3)
   05016 Huntington disease
    79861 (TUBAL3)
   05020 Prion disease
    79861 (TUBAL3)
   05022 Pathways of neurodegeneration - multiple diseases
    79861 (TUBAL3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    79861 (TUBAL3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    79861 (TUBAL3)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    79861 (TUBAL3)
   04147 Exosome [BR:hsa04147]
    79861 (TUBAL3)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     79861 (TUBAL3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     79861 (TUBAL3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    79861 (TUBAL3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   79861 (TUBAL3)
  Exosomal proteins of other body fluids (saliva and urine)
   79861 (TUBAL3)
  Exosomal proteins of colorectal cancer cells
   79861 (TUBAL3)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281 DUF8666
Other DBs
NCBI-GeneID: 79861
NCBI-ProteinID: NP_079079
OMIM: 620835
HGNC: 23534
Ensembl: ENSP00000369784.3
UniProt: A6NHL2
LinkDB
Position
10:complement(5393101..5404828)
AA seq 446 aa
MRECLSIHIGQAGIQIGDACWELYCLEHGIQPNGVVLDTQQDQLENAKMEHTNASFDTFF
CETRAGKHVPRALFVDLEPTVIDGIRTGQHRSLFHPEQLLSGKEDAANNYARGRYSVGSE
VIDLVLERTRKLAEQCGGLQGFLIFRSFGGGTGSGFTSLLMERLTGEYSRKTKLEFSVYP
APRISTAVVEPYNSVLTTHSTTEHTDCTFMVDNEAVYDICHRKLGVECPSHASINRLVVQ
VVSSITASLRFEGPLNVDLIEFQTNLVPYPRIHFPMTAFAPIVSADKAYHEQFSVSDITT
ACFESSNQLVKCDPRLGKYMACCLLYRGDVVPKEVNAAIAATKSRHSVQFVDWCPTGFKV
GINNRPPTVMPGGDLAKVHRSICMLSNTTAIVEAWARLDHKFDLMYAKRAFLHWYLREGM
EEAEFLEAREDLAALERDYEEVAQSF
NT seq 1341 nt   +upstreamnt  +downstreamnt
atgagggagtgcctttccatccacatcggtcaagctggcatccagattggggacgcctgc
tgggaactctattgcctggaacatggaatccagccaaatggcgttgttcttgacactcaa
caggatcagctggaaaatgcaaaaatggagcacacaaatgcatctttcgataccttcttc
tgtgagacaagagctgggaagcatgtgcctagagcactcttcgtggacttggagccaact
gttatagatgggatccggacgggccagcaccgttcactcttccaccccgagcagctcctt
agcggaaaggaggatgctgctaacaattacgcgcgaggccgttactctgtggggtcggag
gtcatcgaccttgtgctggagaggacccggaagctggcagaacagtgtggtggacttcag
ggatttttgattttccgaagctttggaggaggcactggttcagggtttacgtctctctta
atggagaggctcacaggagaatatagcagaaagactaagctggagttctcggtctaccca
gcccccaggatctccactgctgtggtagagccttataactctgtcctcaccacccactcc
accacagagcacacggactgtaccttcatggtggacaacgaggccgtctatgatatatgc
catcgtaaactcggtgttgaatgcccctctcatgccagcatcaatagattggtggttcag
gtggtatcttccatcactgcctccctccggtttgaagggcccttgaatgtagacctaatt
gaattccagaccaacctggtaccttatccgagaatacatttccccatgacagccttcgcc
cccatcgtctctgctgacaaagcctaccatgagcagttctctgtgtcagacatcaccact
gcctgctttgagtcctccaaccagctggtcaagtgtgatcctcggcttgggaagtacatg
gcctgctgcctactctatagaggggatgtggtccccaaggaagtgaatgcagcaatcgca
gccacgaagtcgaggcactctgttcagtttgtagattggtgtccaactggtttcaaggtg
ggcatcaacaatcggccgcccacggtgatgccgggtggggacctggccaaagtccaccgg
tccatctgcatgctgagcaacaccacggcgattgtggaggcctgggcccgcctggaccac
aagtttgacctcatgtacgccaagagagcatttctgcactggtacctcagagaaggcatg
gaagaagcagagttcttggaggccagggaagatctggcagccctggagagggactatgag
gaagtggcgcaaagtttctga

KEGG   Homo sapiens (human): 80086
Entry
80086             CDS       T01001                                 
Symbol
TUBA4B, TUBA4
Name
(RefSeq) tubulin-like protein alpha-4B
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    80086 (TUBA4B)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    80086 (TUBA4B)
  09143 Cell growth and death
   04210 Apoptosis
    80086 (TUBA4B)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    80086 (TUBA4B)
   04540 Gap junction
    80086 (TUBA4B)
  09142 Cell motility
   04814 Motor proteins
    80086 (TUBA4B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    80086 (TUBA4B)
   05132 Salmonella infection
    80086 (TUBA4B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    80086 (TUBA4B)
   05012 Parkinson disease
    80086 (TUBA4B)
   05014 Amyotrophic lateral sclerosis
    80086 (TUBA4B)
   05016 Huntington disease
    80086 (TUBA4B)
   05020 Prion disease
    80086 (TUBA4B)
   05022 Pathways of neurodegeneration - multiple diseases
    80086 (TUBA4B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    80086 (TUBA4B)
   03036 Chromosome and associated proteins [BR:hsa03036]
    80086 (TUBA4B)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    80086 (TUBA4B)
   04147 Exosome [BR:hsa04147]
    80086 (TUBA4B)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     80086 (TUBA4B)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     80086 (TUBA4B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    80086 (TUBA4B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   80086 (TUBA4B)
  Exosomal proteins of other body fluids (saliva and urine)
   80086 (TUBA4B)
  Exosomal proteins of colorectal cancer cells
   80086 (TUBA4B)
SSDB
Motif
Pfam: Tubulin Tubulin_3
Other DBs
NCBI-GeneID: 80086
NCBI-ProteinID: NP_001342150
HGNC: 18637
Ensembl: ENSP00000487719.1
UniProt: Q9H853
LinkDB
Position
2:219253243..219272197
AA seq 241 aa
MRHQQTERQDPSQPLSRQHGTYRQIFHPEQLITGKEDAANNYAWGHYTIGKEFIDLLLDR
IRKLADQCTGLQGFLVFHSLGRGTGSDVTSFLMEWLSVNYGKKSKLGFSIYPAPQVSTAM
VQPYNSILTTHTTLEHSDCAFMVDNKAIYDICHCNLDIERPTYTNLNRLISQIVSSITAS
LRFDGALNVDLTEFQTNLVSYLTSTSPWPPMHQSSLQKRYTTSSCWWQRLPMPALSLPTR
W
NT seq 726 nt   +upstreamnt  +downstreamnt
atgcggcaccagcagacagagagacaagaccccagccagcccctgtccaggcagcatggc
acataccgccagatcttccatccagagcagctcatcacaggcaaggaagatgctgccaat
aactatgcctggggccactacaccattgggaaggagttcatcgacctgctactggaccgg
attcggaagctggctgaccagtgcacaggacttcagggcttcctggtgttccacagcctt
ggtcggggcactggctctgacgtcacctcattcctgatggagtggctttctgttaactat
ggcaagaaatccaagctgggattctccatctacccagccccccaggtgtctacagccatg
gtccagccctacaactctatcctgaccacccacaccaccctggagcactcagactgtgcc
ttcatggtggacaacaaagcaatctatgacatctgccactgcaacctagacatcgagcgc
ccaacctacaccaacctcaatcgcctcattagccaaattgtctcctccatcacagcttct
ctgcgctttgacggggccctcaatgtggacctgacagagttccagaccaacctggtgtcc
tacctcacatccacttccccctggccacctatgcaccagtcatctctgcagaaaaggtat
accacgagcagctgttggtggcagagattaccaatgcctgctttgagcctgccaaccaga
tggtga

KEGG   Homo sapiens (human): 84790
Entry
84790             CDS       T01001                                 
Symbol
TUBA1C, OZEMA24, TUBA6, bcm948
Name
(RefSeq) tubulin alpha-1C chain isoform c
  KO
K07374  tubulin alpha
Organism
hsa  Homo sapiens (human)
Pathway
hsa04145  Phagocytosis
hsa04210  Apoptosis
hsa04517  IgSF CAM signaling
hsa04530  Tight junction
hsa04540  Gap junction
hsa04814  Motor proteins
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05130  Pathogenic Escherichia coli infection
hsa05132  Salmonella infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06460  Alzheimer disease
nt06461  Huntington disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06465  Prion disease
nt06466  Pathways of neurodegeneration
nt06515  Regulation of kinetochore-microtubule interactions
nt06541  Cytoskeleton in neurons
nt06546  IgSF CAM signaling
  Element
N00976  Retrograde axonal transport
N00977  Mutation-caused aberrant Htt to retrograde axonal transport
N00978  Anterograde axonal transport
N00979  Mutation-caused aberrant Htt to anterograde axonal transport
N01018  Mutation-caused aberrant Abeta to anterograde axonal transport
N01055  Mutation-caused aberrant SNCA to anterograde axonal transport
N01158  Mutation-caused aberrant DCTN1 to retrograde axonal transport
N01285  Microtubule-RHOA signaling pathway
N01286  Escherichia EspG to Microtubule-RHOA signaling pathway
N01295  Rab7-regulated microtubule minus-end directed transport
N01297  Arl8-regulated microtubule plus-end directed transport
N01298  Salmonella SifA to microtubule plus-end directed transport
N01299  Salmonella PipB2 to microtubule plus-end directed transport
N01403  Zn to anterograde axonal transport
N01414  Iron to anterograde axonal transport
N01535  Kinetochore microtubule attachment
N01544  Microtubule nucleation
N01547  Kinetochore fiber organization
N01549  Branching microtubule nucleation
N01553  Promotion of microtubule growth
N01561  Microtubule depolymerization
N01562  Microtubule depolymerization at the minus ends
N01832  NTN1-MAP1B axon guidance signaling
N01833  DRAXIN-MAP1B axon guidance signaling
N01834  SEMA3A-MAP1B axon guidance signaling
N01835  SEMA3-CRMP2/MAPT axon guidance signaling
N01836  Microtubule plus end regulation network
N01837  Regulation of neurite extension, NAV1-TRIO
N01838  Regulation of synaptic plasticity, p140Cap
N01839  Severing of microtubule, SPAST/KATN
N01840  Severing of microtubule, KIF2A
N01841  Anterograde axonal transport, Kinesin-2
N01842  Anterograde axonal/dendrite transport, Kinesin-3
N01843  Anterograde dendrite transport, Kinesin-4
N01844  Anterograde dendrite transport, Kinesin-6
N01845  Anterograde axonal/dendrite transport, Kinesin-12
N01846  Retrograde axonal/dendrite transport, Dynein
N01847  Regulation of dynein-mediated retrograde transport
N01857  SEMA3A-DCX axon guidance signaling
N01858  EFNB1-MAPT axon guidance signaling
N01859  Anterograde axonal/dendrite transport, Kinesin-1
N01934  L1CAM interactions
N01939  Ganglioside-MAG signaling
Disease
H01897  Oocyte/zygote/embryo maturation arrest
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    84790 (TUBA1C)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagocytosis
    84790 (TUBA1C)
  09143 Cell growth and death
   04210 Apoptosis
    84790 (TUBA1C)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    84790 (TUBA1C)
   04540 Gap junction
    84790 (TUBA1C)
  09142 Cell motility
   04814 Motor proteins
    84790 (TUBA1C)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    84790 (TUBA1C)
   05132 Salmonella infection
    84790 (TUBA1C)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    84790 (TUBA1C)
   05012 Parkinson disease
    84790 (TUBA1C)
   05014 Amyotrophic lateral sclerosis
    84790 (TUBA1C)
   05016 Huntington disease
    84790 (TUBA1C)
   05020 Prion disease
    84790 (TUBA1C)
   05022 Pathways of neurodegeneration - multiple diseases
    84790 (TUBA1C)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    84790 (TUBA1C)
   03036 Chromosome and associated proteins [BR:hsa03036]
    84790 (TUBA1C)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    84790 (TUBA1C)
   04147 Exosome [BR:hsa04147]
    84790 (TUBA1C)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     84790 (TUBA1C)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Microtubules and associated factors
    Other tubulins
     84790 (TUBA1C)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulins
    84790 (TUBA1C)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   84790 (TUBA1C)
  Exosomal proteins of other body fluids (saliva and urine)
   84790 (TUBA1C)
  Exosomal proteins of colorectal cancer cells
   84790 (TUBA1C)
SSDB
Motif
Pfam: Tubulin Tubulin_C Tubulin_3 DUF7281
Other DBs
NCBI-GeneID: 84790
NCBI-ProteinID: NP_116093
OMIM: 621161
HGNC: 20768
Ensembl: ENSP00000301072.7
UniProt: Q9BQE3
LinkDB
Position
12:49227926..49274600
AA seq 449 aa
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD
RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA
VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA
SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPAN
QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE
AREDMAALEKDYEEVGADSADGEDEGEEY
NT seq 1350 nt   +upstreamnt  +downstreamnt
atgcgtgagtgcatctccatccacgttggccaggctggtgtccagattggcaatgcctgc
tgggagctctactgcctggaacacggcatccagcccgatggccagatgccaagtgacaag
accattgggggaggagatgattccttcaacaccttcttcagtgaaacgggtgctggcaag
catgtgccccgggcagtgtttgtagacttggaacccacagtcattgatgaagttcgcact
ggcacttaccgccagctcttccaccctgagcaactcatcacaggcaaggaagatgctgcc
aataactatgcccgagggcactacaccattggcaaggagatcattgacctcgtgttggac
cgaattcgcaagctggctgaccagtgcaccggtcttcagggcttcttggttttccacagc
tttggtgggggaactggttctgggttcacctcgctgctcatggaacgtctctcagttgat
tatggcaagaagtccaagctggagttctccatttacccggcgccccaggtttccacagct
gtagttgagccctacaactccatcctcaccacccacaccaccctggagcactctgattgt
gccttcatggtagacaatgaggccatctatgacatctgtcgtagaaacctcgatatcgag
cgcccaacctacactaaccttaaccgccttattagccagattgtgtcctccatcactgct
tccctgagatttgatggagccctgaatgttgacctgacagaattccagaccaacctggtg
ccctacccccgcatccacttccctctggccacatatgcccctgtcatctctgctgagaaa
gcctaccacgaacagcttactgtagcagagatcaccaatgcttgctttgagccagccaac
cagatggtgaaatgtgaccctcgccatggtaaatacatggcttgctgcctgttataccgt
ggtgacgtggttcccaaagatgtcaatgctgccattgccaccatcaaaaccaagcgtacc
atccagtttgtggattggtgccccactggcttcaaggttggcattaattaccagcctccc
actgtggtgcctggcggagacctggccaaggtacagagagctgtgtgcatgctgagcaat
accacagctgttgccgaggcctgggctcgcctggaccacaagtttgacctgatgtatgcc
aagcgtgcctttgttcactggtacgtgggtgaggggatggaggaaggcgagttttcagag
gcccgtgaggacatggctgcccttgagaaggattatgaggaggttggagcagatagtgct
gacggagaggatgagggtgaagagtattaa

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