KEGG   Homo sapiens (human): 103910
Entry
103910            CDS       T01001                                 
Symbol
MYL12B, MLC-B, MRLC2
Name
(RefSeq) myosin light chain 12B
  KO
K12757  myosin regulatory light chain 12
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04530  Tight junction
hsa04611  Platelet activation
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06182  Shigella
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103910 (MYL12B)
   04520 Adherens junction
    103910 (MYL12B)
   04530 Tight junction
    103910 (MYL12B)
  09142 Cell motility
   04814 Motor proteins
    103910 (MYL12B)
   04810 Regulation of actin cytoskeleton
    103910 (MYL12B)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103910 (MYL12B)
   04670 Leukocyte transendothelial migration
    103910 (MYL12B)
  09158 Development and regeneration
   04360 Axon guidance
    103910 (MYL12B)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103910 (MYL12B)
   05131 Shigellosis
    103910 (MYL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    103910 (MYL12B)
   04147 Exosome [BR:hsa04147]
    103910 (MYL12B)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     103910 (MYL12B)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   103910 (MYL12B)
SSDB
Motif
Pfam: EF-hand_7 EF-hand_1 EF-hand_6 AIF-1 EF-hand_5 EF-hand_8 EF-hand_11 EF-hand_9 DUF2666 SPARC_Ca_bdg 2-Hacid_dh_C
Other DBs
NCBI-GeneID: 103910
NCBI-ProteinID: NP_001138416
OMIM: 609211
HGNC: 29827
Ensembl: ENSG00000118680
UniProt: O14950
LinkDB
Position
18:3262133..3278461
AA seq 172 aa
MSSKKAKTKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLAS
LGKNPTDAYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQE
DYLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
NT seq 519 nt   +upstreamnt  +downstreamnt
atgtcgagcaaaaaggcaaagaccaagaccaccaagaagcgccctcagcgtgcaacatcc
aatgtgtttgccatgtttgaccagtcacagattcaggagttcaaagaggccttcaacatg
attgatcagaacagagatggcttcatcgacaaggaagatttgcatgatatgcttgcttct
ctagggaagaatcccactgatgcataccttgatgccatgatgaatgaggccccagggccc
atcaatttcaccatgttcctgaccatgtttggtgagaagttaaatggcacagatcctgaa
gatgtcatcagaaacgcctttgcttgctttgatgaagaagcaacaggcaccattcaggaa
gattacctaagagagctgctgacaaccatgggggatcggtttacagatgaggaagtggat
gagctgtacagagaagcacctattgacaaaaaggggaatttcaattacatcgagttcaca
cgcatcctgaaacatggagccaaagacaaagatgactga

KEGG   Homo sapiens (human): 10627
Entry
10627             CDS       T01001                                 
Symbol
MYL12A, HEL-S-24, MLC-2B, MLCB, MRCL3, MRLC3, MYL2B
Name
(RefSeq) myosin light chain 12A
  KO
K12757  myosin regulatory light chain 12
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04530  Tight junction
hsa04611  Platelet activation
hsa04670  Leukocyte transendothelial migration
hsa04810  Regulation of actin cytoskeleton
hsa04814  Motor proteins
hsa05131  Shigellosis
hsa05132  Salmonella infection
Network
nt06181  Salmonella
nt06182  Shigella
  Element
N01074  Shigella IpaA to ITGA/B-RhoGEF-RhoA signaling pathway
N01130  Salmonella SopB to RhoA signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    10627 (MYL12A)
   04520 Adherens junction
    10627 (MYL12A)
   04530 Tight junction
    10627 (MYL12A)
  09142 Cell motility
   04814 Motor proteins
    10627 (MYL12A)
   04810 Regulation of actin cytoskeleton
    10627 (MYL12A)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    10627 (MYL12A)
   04670 Leukocyte transendothelial migration
    10627 (MYL12A)
  09158 Development and regeneration
   04360 Axon guidance
    10627 (MYL12A)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    10627 (MYL12A)
   05131 Shigellosis
    10627 (MYL12A)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10627 (MYL12A)
   04147 Exosome [BR:hsa04147]
    10627 (MYL12A)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     10627 (MYL12A)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   10627 (MYL12A)
SSDB
Motif
Pfam: EF-hand_7 EF-hand_1 EF-hand_6 AIF-1 EF-hand_11 EF-hand_5 EF-hand_8 EF-hand_9 DUF2666 SPARC_Ca_bdg
Other DBs
NCBI-GeneID: 10627
NCBI-ProteinID: NP_001289976
HGNC: 16701
Ensembl: ENSG00000101608
UniProt: P19105
LinkDB
Position
18:3247482..3256237
AA seq 171 aa
MSSKRTKTKTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASL
GKNPTDEYLDAMMNEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEATGTIQED
YLRELLTTMGDRFTDEEVDELYREAPIDKKGNFNYIEFTRILKHGAKDKDD
NT seq 516 nt   +upstreamnt  +downstreamnt
atgtcgagcaaaagaacaaagaccaagaccaagaagcgccctcagcgtgcaacatccaat
gtgtttgctatgtttgaccagtcacagattcaggagttcaaagaggccttcaacatgatt
gatcagaacagagatggtttcatcgacaaggaagatttgcatgatatgcttgcttcattg
gggaagaatccaactgatgagtatctagatgccatgatgaatgaggctccaggccccatc
aatttcaccatgttcctcaccatgtttggtgagaagttaaatggcacagatcctgaagat
gtcatcagaaatgcctttgcttgctttgatgaagaagcaactggcaccatacaggaagat
tacttgagagagctgctgacaaccatgggggatcggtttacagatgaggaagtggatgag
ctgtacagagaagcacctattgataaaaaggggaatttcaattacatcgagttcacacgc
atcctgaaacatggagccaaagacaaagatgactga

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