Homo sapiens (human): 1056 Help Entry 1056              CDS       T01001                                  Symbol CEL, BAL, BSDL, BSSL, CELL, CEase, FAP, FAPP, LIPA, MODY8 Name (RefSeq) carboxyl ester lipase   KO K12298   bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13] Organism hsa  Homo sapiens (human) Pathway hsa00100   Steroid biosynthesis hsa00561   Glycerolipid metabolism hsa01100   Metabolic pathways hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Module hsa_M00098   Acylglycerol degradation Disease H00410   Maturity onset diabetes of the young (MODY) Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00100 Steroid biosynthesis     1056 (CEL)    00561 Glycerolipid metabolism     1056 (CEL)  09150 Organismal Systems   09154 Digestive system    04972 Pancreatic secretion     1056 (CEL)    04975 Fat digestion and absorption     1056 (CEL)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     1056 (CEL) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.3  triacylglycerol lipase      1056 (CEL)     3.1.1.13  sterol esterase      1056 (CEL) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of breast milk    1056 (CEL) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  COesterase Mucin-like BD-FAE Abhydrolase_3 Say1_Mug180 Motif Other DBs NCBI-GeneID:  1056 NCBI-ProteinID:  NP_001798 OMIM:  114840 HGNC:  1848 Ensembl:  ENSG00000170835 UniProt:  B4DSX9 Q86SR3 O75612 LinkDB All DBs Position 9:133061981..133071861 Genome browser AA seq 753 aa AA seqDB search MGRLQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTK ALENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGDEDCLYLNIWVPQGRKQVSRDLPV MIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPG NYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQS GVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYP MLHYVGFVPVIDGDFIPADPINLYANAADIDYIAGTNNMDGHIFASIDMPAINKGNKKVT EEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIA LAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRPQDRTV SKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLR YWTLTYLALPTVTDQEATPVPPTGDSEATPVPPTGDSETAPVPPTGDSGAPPVPPTGDSG APPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVPPTGDSGAPPVP PTGDSGAPPVPPTGDAGPPPVPPTGDSGAPPVPPTGDSGAPPVTPTGDSETAPVPPTGDS GAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIRF NT seq 2262 nt NT seq  +upstreamnt  +downstreamnt atggggcgcctgcaactggttgtgttgggcctcacctgctgctgggcagtggcgagtgcc gcgaagctgggcgccgtgtacacagaaggtgggttcgtggaaggcgtcaataagaagctc ggcctcctgggtgactctgtggacatcttcaagggcatccccttcgcagctcccaccaag gccctggaaaatcctcagccacatcctggctggcaagggaccctgaaggccaagaacttc aagaagagatgcctgcaggccaccatcacccaggacagcacctacggggatgaagactgc ctgtacctcaacatttgggtgccccagggcaggaagcaagtctcccgggacctgcccgtt atgatctggatctatggaggcgccttcctcatggggtccggccatggggccaacttcctc aacaactacctgtatgacggcgaggagatcgccacacgcggaaacgtcatcgtggtcacc ttcaactaccgtgtcggcccccttgggttcctcagcactggggacgccaatctgccaggt aactatggccttcgggatcagcacatggccattgcttgggtgaagaggaatatcgcggcc ttcgggggggaccccaacaacatcacgctcttcggggagtctgctggaggtgccagcgtc tctctgcagaccctctccccctacaacaagggcctcatccggcgagccatcagccagagc ggcgtggccctgagtccctgggtcatccagaaaaacccactcttctgggccaaaaaggtg gctgagaaggtgggttgccctgtgggtgatgccgccaggatggcccagtgtctgaaggtt actgatccccgagccctgacgctggcctataaggtgccgctggcaggcctggagtacccc atgctgcactatgtgggcttcgtccctgtcattgatggagacttcatccccgctgacccg atcaacctgtacgccaacgccgccgacatcgactatatagcaggcaccaacaacatggac ggccacatcttcgccagcatcgacatgcctgccatcaacaagggcaacaagaaagtcacg gaggaggacttctacaagctggtcagtgagttcacaatcaccaaggggctcagaggcgcc aagacgacctttgatgtctacaccgagtcctgggcccaggacccatcccaggagaataag aagaagactgtggtggactttgagaccgatgtcctcttcctggtgcccaccgagattgcc ctagcccagcacagagccaatgccaagagtgccaagacctacgcctacctgttttcccat ccctctcggatgcccgtctaccccaaatgggtgggggccgaccatgcagatgacattcag tacgttttcgggaagcccttcgccacccccacgggctaccggccccaagacaggacagtc tctaaggccatgatcgcctactggaccaactttgccaaaacaggggaccccaacatgggc gactcggctgtgcccacacactgggaaccctacactacggaaaacagcggctacctggag atcaccaagaagatgggcagcagctccatgaagcggagcctgagaaccaacttcctgcgc tactggaccctcacctatctggcgctgcccacagtgaccgaccaggaggccacccctgtg ccccccacaggggactccgaggccactcccgtgccccccacgggtgactccgagaccgcc cccgtgccgcccacgggtgactccggggccccccccgtgccgcccacgggtgactccggg gccccccccgtgccgcccacgggtgactccggggccccccccgtgccgcccacgggtgac tccggggccccccccgtgccgcccacgggtgactccggggccccccccgtgccgcccacg ggtgactccggggccccccccgtgccgcccacgggtgactccggggccccccccgtgccg cccacgggtgactccggcgccccccccgtgccgcccacgggtgacgccgggccccccccc gtgccgcccacgggtgactccggcgccccccccgtgccgcccacgggtgactccggggcc ccccccgtgacccccacgggtgactccgagaccgcccccgtgccgcccacgggtgactcc ggggccccccctgtgccccccacgggtgactctgaggctgcccctgtgccccccacagat gactccaaggaagctcagatgcctgcagtcattaggttttag

Homo sapiens (human): 26279 Help Entry 26279             CDS       T01001                                  Symbol PLA2G2D, PLA2IID, SPLASH, sPLA2-IID, sPLA2S Name (RefSeq) phospholipase A2 group IID   KO K01047   secretory phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04014   Ras signaling pathway hsa04270   Vascular smooth muscle contraction hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Drug target Varespladib (DG01394):  D06283 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     26279 (PLA2G2D)    00565 Ether lipid metabolism     26279 (PLA2G2D)    00590 Arachidonic acid metabolism     26279 (PLA2G2D)    00591 Linoleic acid metabolism     26279 (PLA2G2D)    00592 alpha-Linolenic acid metabolism     26279 (PLA2G2D)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     26279 (PLA2G2D)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     26279 (PLA2G2D)   09154 Digestive system    04972 Pancreatic secretion     26279 (PLA2G2D)    04975 Fat digestion and absorption     26279 (PLA2G2D)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     26279 (PLA2G2D) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      26279 (PLA2G2D) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centriole proteins     26279 (PLA2G2D) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phospholip_A2_1 DUF5460 Motif Other DBs NCBI-GeneID:  26279 NCBI-ProteinID:  NP_036532 OMIM:  605630 HGNC:  9033 Ensembl:  ENSG00000117215 Pharos:  Q9UNK4(Tchem) UniProt:  Q9UNK4 LinkDB All DBs Position 1:complement(20111939..20119536) Genome browser AA seq 145 aa AA seqDB search MELALLCGLVVMAGVIPIQGGILNLNKMVKQVTGKMPILSYWPYGCHCGLGGRGQPKDAT DWCCQTHDCCYDHLKTQGCSIYKDYYRYNFSQGNIHCSDKGSWCEQQLCACDKEVAFCLK RNLDTYQKRLRFYWRPHCRGQTPGC NT seq 438 nt NT seq  +upstreamnt  +downstreamnt atggaacttgcactgctgtgtgggctggtggtgatggctggtgtgattccaatccagggc gggatcctgaacctgaacaagatggtcaagcaagtgactgggaaaatgcccatcctctcc tactggccctacggctgtcactgcggactaggtggcagaggccaacccaaagatgccacg gactggtgctgccagacccatgactgctgctatgaccacctgaagacccaggggtgcagc atctacaaggactattacagatacaacttttcccaggggaacatccactgctctgacaag ggaagctggtgtgagcagcagctgtgtgcctgtgacaaggaggtggccttctgcctgaag cgcaacctggacacctaccagaagcgactgcgtttctactggcggccccactgccggggg cagacccctgggtgctag

Homo sapiens (human): 30814 Help Entry 30814             CDS       T01001                                  Symbol PLA2G2E, GIIE_sPLA2, sPLA2-IIE Name (RefSeq) phospholipase A2 group IIE   KO K01047   secretory phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04014   Ras signaling pathway hsa04270   Vascular smooth muscle contraction hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Drug target Varespladib (DG01394):  D06283 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     30814 (PLA2G2E)    00565 Ether lipid metabolism     30814 (PLA2G2E)    00590 Arachidonic acid metabolism     30814 (PLA2G2E)    00591 Linoleic acid metabolism     30814 (PLA2G2E)    00592 alpha-Linolenic acid metabolism     30814 (PLA2G2E)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     30814 (PLA2G2E)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     30814 (PLA2G2E)   09154 Digestive system    04972 Pancreatic secretion     30814 (PLA2G2E)    04975 Fat digestion and absorption     30814 (PLA2G2E)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     30814 (PLA2G2E) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      30814 (PLA2G2E) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centriole proteins     30814 (PLA2G2E) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phospholip_A2_1 Motif Other DBs NCBI-GeneID:  30814 NCBI-ProteinID:  NP_055404 OMIM:  618320 HGNC:  13414 Ensembl:  ENSG00000188784 Pharos:  Q9NZK7(Tchem) UniProt:  Q9NZK7 Structure PDB LinkDB All DBs Position 1:complement(19920009..19923617) Genome browser AA seq 142 aa AA seqDB search MKSPHVLVFLCLLVALVTGNLVQFGVMIEKMTGKSALQYNDYGCYCGIGGSHWPVDQTDW CCHAHDCCYGRLEKLGCEPKLEKYLFSVSERGIFCAGRTTCQRLTCECDKRAALCFRRNL GTYNRKYAHYPNKLCTGPTPPC NT seq 429 nt NT seq  +upstreamnt  +downstreamnt atgaaatctccccacgtgctggtgttcctttgcctcctggtggctctggtcaccgggaac ctggttcagtttggggtgatgatcgagaagatgacaggcaagtccgccctgcagtacaac gactatggctgttactgcggcatcggtggctcccactggccggtggaccagactgactgg tgctgccacgcccacgactgctgctacgggcgtctggagaagctgggctgtgagcccaaa ctggaaaagtatcttttctctgtcagcgaacgtggcattttctgcgccggcaggaccacc tgccagcggctgacctgcgagtgtgacaagagggctgccctctgctttcgccgcaacctg ggcacctacaaccgcaaatatgcccattatcccaacaagctgtgcaccgggcccaccccg ccctgctga

Homo sapiens (human): 391013 Help Entry 391013            CDS       T01001                                  Symbol PLA2G2C, UBXN10-AS1 Name (RefSeq) phospholipase A2 group IIC   KO K01047   secretory phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04014   Ras signaling pathway hsa04270   Vascular smooth muscle contraction hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Drug target Varespladib (DG01394):  D06283 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     391013 (PLA2G2C)    00565 Ether lipid metabolism     391013 (PLA2G2C)    00590 Arachidonic acid metabolism     391013 (PLA2G2C)    00591 Linoleic acid metabolism     391013 (PLA2G2C)    00592 alpha-Linolenic acid metabolism     391013 (PLA2G2C)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     391013 (PLA2G2C)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     391013 (PLA2G2C)   09154 Digestive system    04972 Pancreatic secretion     391013 (PLA2G2C)    04975 Fat digestion and absorption     391013 (PLA2G2C)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     391013 (PLA2G2C) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      391013 (PLA2G2C) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centriole proteins     391013 (PLA2G2C) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phospholip_A2_1 Motif Other DBs NCBI-GeneID:  391013 NCBI-ProteinID:  NP_001354898 HGNC:  9032 Ensembl:  ENSG00000187980 UniProt:  Q5R387 LinkDB All DBs Position 1:complement(20163055..20186518) Genome browser AA seq 149 aa AA seqDB search MKVIAILTLLLFCSPTHSSFWQFQRRVKHITGRSAFFSYYGYGCYCGLGDKGIPVDDTDR HSPSSPSPYEKLKEFSCQPVLNSYQFHIVNGAVVCGCTLGPGASCHCRLKACECDKQSVH CFKESLPTYEKNFKQFSSQPRCGRHKPWC NT seq 450 nt NT seq  +upstreamnt  +downstreamnt atgaaggtcattgccatcctcaccctcctcctcttctgctcccccacccacagcagtttc tggcagtttcagaggagggtcaaacacatcacggggcgaagtgccttcttctcatattac ggatatggctgctactgtgggcttggggataaagggatccccgtggatgacactgacagg cacagcccctcatctccctctccctacgagaagctgaaggagttcagctgccagcctgtg ttgaacagctaccagttccacatcgtcaatggcgcagtggtttgtggatgcacccttggt cctggtgccagctgccactgcaggctgaaggcctgtgagtgtgacaagcaatccgtgcac tgcttcaaagagagcctgcccacctatgagaaaaacttcaagcagttctccagccagccc aggtgtggcagacataagccctggtgctag

Homo sapiens (human): 50487 Help Entry 50487             CDS       T01001                                  Symbol PLA2G3, GIII-SPLA2, SPLA2III, sPLA2-III Name (RefSeq) phospholipase A2 group III   KO K01047   secretory phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04014   Ras signaling pathway hsa04270   Vascular smooth muscle contraction hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Drug target Varespladib (DG01394):  D06283 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     50487 (PLA2G3)    00565 Ether lipid metabolism     50487 (PLA2G3)    00590 Arachidonic acid metabolism     50487 (PLA2G3)    00591 Linoleic acid metabolism     50487 (PLA2G3)    00592 alpha-Linolenic acid metabolism     50487 (PLA2G3)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     50487 (PLA2G3)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     50487 (PLA2G3)   09154 Digestive system    04972 Pancreatic secretion     50487 (PLA2G3)    04975 Fat digestion and absorption     50487 (PLA2G3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     50487 (PLA2G3) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      50487 (PLA2G3) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centriole proteins     50487 (PLA2G3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phospholip_A2_2 Chromadorea_ALT Motif Other DBs NCBI-GeneID:  50487 NCBI-ProteinID:  NP_056530 OMIM:  611651 HGNC:  17934 Ensembl:  ENSG00000100078 Pharos:  Q9NZ20(Tbio) UniProt:  Q9NZ20 LinkDB All DBs Position 22:complement(31134807..31140508) Genome browser AA seq 509 aa AA seqDB search MGVQAGLFGMLGFLGVALGGSPALRWYRTSCHLTKAVPGNPLGYLSFLAKDAQGLALIHA RWDAHRRLQSCSWEDEPELTAAYGALCAHETAWGSFIHTPGPELQRALATLQSQWEACRA LEESPAGARKKRAAGQSGVPGGGHQREKRGWTMPGTLWCGVGDSAGNSSELGVFQGPDLC CREHDRCPQNISPLQYNYGIRNYRFHTISHCDCDTRFQQCLQNQHDSISDIVGVAFFNVL EIPCFVLEEQEACVAWYWWGGCRMYGTVPLARLQPRTFYNASWSSRATSPTPSSRSPAPP KPRQKQHLRKGPPHQKGSKRPSKANTTALQDPMVSPRLDVAPTGLQGPQGGLKPQGARWV CRSFRRHLDQCEHQIGPREIEFQLLNSAQEPLFHCNCTRRLARFLRLHSPPEVTNMLWEL LGTTCFKLAPPLDCVEGKNCSRDPRAIRVSARHLRRLQQRRHQLQDKGTDERQPWPSEPL RGPMSFYNQCLQLTQAARRPDRQQKSWSQ NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggggttcaggcagggctgtttgggatgctgggcttcctgggggtggccctggggggc tcccctgccctccgctggtacaggacctcctgccacttgaccaaggccgtccctggcaac ccactggggtacctgagcttcctggccaaggatgctcagggactggccctgatccatgcc cgctgggatgcgcataggaggctgcagtcatgtagctgggaggatgagccggagctcacc gcagcctacggtgctctctgtgctcatgagactgcctggggctccttcatccacaccccc ggacccgagctgcagagagcactggccactcttcagagtcagtgggaggcatgccgagcg cttgaggagagtccagcaggggccaggaagaagcgagcagcagggcagagtggagtccct ggtggagggcaccagcgagagaagagaggatggaccatgcctggcacactgtggtgtgga gttggagattctgctgggaactcctcggagctgggggtcttccagggacctgatctctgt tgccgggaacatgaccgctgcccacagaacatctcacccttgcagtacaactatggcatc cgaaactaccgattccacaccatctcccactgtgactgtgacaccaggtttcagcaatgc ctacagaatcagcacgactccatctcggacatcgtgggcgtggccttcttcaacgtgctg gagatcccctgctttgtgctggaggagcaggaggcgtgtgtggcgtggtactggtggggc gggtgtaggatgtacggcacagtgcccctcgctcgcctgcagcccaggaccttctacaat gcctcctggagctcccgggccacctccccaactcccagctcccggagcccagcccctccc aagcctcgacagaagcagcaccttcggaaggggccaccacatcagaaagggtccaagcgc cccagcaaagccaacaccacagccctccaggaccctatggtctctcccaggcttgatgtg gcccccacaggcctccagggcccacagggtggcctaaaacctcagggtgcccgctgggtc tgccgcagcttccgccgccacctggaccagtgtgagcaccagattgggccccgggaaatc gagttccagctgctcaacagcgcccaagagcccctcttccactgcaactgcacgcgccgt ctggcacgcttcctgaggctccacagcccacccgaggttaccaacatgctttgggagctg ctgggcacaacctgcttcaagctggcccctccactggactgtgtggaaggcaaaaactgt tccagagaccctagggccatcagggtgtcagcccggcacttgcggaggcttcagcagagg cgacaccagctccaggataaaggcacagatgagaggcagccatggccttcagagcccctg agaggccccatgtcattctacaaccagtgcctgcagctaacccaggcagccaggagaccc gacaggcagcagaagtcctggagccagtga

Homo sapiens (human): 5319 Help Entry 5319              CDS       T01001                                  Symbol PLA2G1B, PLA2, PLA2A, PPLA2 Name (RefSeq) phospholipase A2 group IB   KO K01047   secretory phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04014   Ras signaling pathway hsa04270   Vascular smooth muscle contraction hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Drug target Varespladib (DG01394):  D06283 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     5319 (PLA2G1B)    00565 Ether lipid metabolism     5319 (PLA2G1B)    00590 Arachidonic acid metabolism     5319 (PLA2G1B)    00591 Linoleic acid metabolism     5319 (PLA2G1B)    00592 alpha-Linolenic acid metabolism     5319 (PLA2G1B)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     5319 (PLA2G1B)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     5319 (PLA2G1B)   09154 Digestive system    04972 Pancreatic secretion     5319 (PLA2G1B)    04975 Fat digestion and absorption     5319 (PLA2G1B)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     5319 (PLA2G1B) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      5319 (PLA2G1B) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centriole proteins     5319 (PLA2G1B) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phospholip_A2_1 Phospholip_A2_4 Phospholip_A2_2 DUF1644 Motif Other DBs NCBI-GeneID:  5319 NCBI-ProteinID:  NP_000919 OMIM:  172410 HGNC:  9030 Ensembl:  ENSG00000170890 Pharos:  P04054(Tchem) UniProt:  P04054 Structure PDB LinkDB All DBs Position 12:complement(120322115..120327779) Genome browser AA seq 148 aa AA seqDB search MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPV DELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNC DRNAAICFSKAPYNKAHKNLDTKKYCQS NT seq 447 nt NT seq  +upstreamnt  +downstreamnt atgaaactccttgtgctagctgtgctgctcacagtggccgccgccgacagcggcatcagc cctcgggccgtgtggcagttccgcaaaatgatcaagtgcgtgatcccggggagtgacccc ttcttggaatacaacaactacggctgctactgtggcttggggggctcaggcacccccgtg gatgaactggacaagtgctgccagacacatgacaactgctatgaccaggccaagaagctg gacagctgtaaatttctgctggacaacccgtacacccacacctattcatactcgtgctct ggctcggcaatcacctgtagcagcaaaaacaaagagtgtgaggccttcatttgcaactgc gaccgcaacgctgccatctgcttttcaaaagctccatataacaaggcacacaagaacctg gacaccaagaagtattgtcagagttga

Homo sapiens (human): 5320 Help Entry 5320              CDS       T01001                                  Symbol PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2 Name (RefSeq) phospholipase A2 group IIA   KO K01047   secretory phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04014   Ras signaling pathway hsa04270   Vascular smooth muscle contraction hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Drug target Varespladib (DG01394):  D06283 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     5320 (PLA2G2A)    00565 Ether lipid metabolism     5320 (PLA2G2A)    00590 Arachidonic acid metabolism     5320 (PLA2G2A)    00591 Linoleic acid metabolism     5320 (PLA2G2A)    00592 alpha-Linolenic acid metabolism     5320 (PLA2G2A)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     5320 (PLA2G2A)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     5320 (PLA2G2A)   09154 Digestive system    04972 Pancreatic secretion     5320 (PLA2G2A)    04975 Fat digestion and absorption     5320 (PLA2G2A)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     5320 (PLA2G2A) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      5320 (PLA2G2A) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centriole proteins     5320 (PLA2G2A) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phospholip_A2_1 Motif Other DBs NCBI-GeneID:  5320 NCBI-ProteinID:  NP_000291 OMIM:  172411 HGNC:  9031 Ensembl:  ENSG00000188257 Pharos:  P14555(Tchem) UniProt:  P14555 A0A024RA96 Structure PDB LinkDB All DBs Position 1:complement(19975431..19980434) Genome browser AA seq 144 aa AA seqDB search MKTLLLLAVIMIFGLLQAHGNLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDAT DRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFAR NKTTYNKKYQYYSNKHCRGSTPRC NT seq 435 nt NT seq  +upstreamnt  +downstreamnt atgaagaccctcctactgttggcagtgatcatgatctttggcctactgcaggcccatggg aatttggtgaatttccacagaatgatcaagttgacgacaggaaaggaagccgcactcagt tatggcttctacggctgccactgtggcgtgggtggcagaggatcccccaaggatgcaacg gatcgctgctgtgtcactcatgactgttgctacaaacgtctggagaaacgtggatgtggc accaaatttctgagctacaagtttagcaactcggggagcagaatcacctgtgcaaaacag gactcctgcagaagtcaactgtgtgagtgtgataaggctgctgccacctgttttgctaga aacaagacgacctacaataaaaagtaccagtactattccaataaacactgcagagggagc acccctcgttgctga

Homo sapiens (human): 5322 Help Entry 5322              CDS       T01001                                  Symbol PLA2G5, FRFB, GV-PLA2, PLA2-10, hVPLA(2) Name (RefSeq) phospholipase A2 group V   KO K01047   secretory phospholipase A2 [EC:3.1.1.4] Organism hsa  Homo sapiens (human) Pathway hsa00564   Glycerophospholipid metabolism hsa00565   Ether lipid metabolism hsa00590   Arachidonic acid metabolism hsa00591   Linoleic acid metabolism hsa00592   alpha-Linolenic acid metabolism hsa01100   Metabolic pathways hsa04014   Ras signaling pathway hsa04270   Vascular smooth muscle contraction hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Disease H02440   Fleck retina, familial benign Drug target Varespladib (DG01394):  D06283 Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     5322 (PLA2G5)    00565 Ether lipid metabolism     5322 (PLA2G5)    00590 Arachidonic acid metabolism     5322 (PLA2G5)    00591 Linoleic acid metabolism     5322 (PLA2G5)    00592 alpha-Linolenic acid metabolism     5322 (PLA2G5)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     5322 (PLA2G5)  09150 Organismal Systems   09153 Circulatory system    04270 Vascular smooth muscle contraction     5322 (PLA2G5)   09154 Digestive system    04972 Pancreatic secretion     5322 (PLA2G5)    04975 Fat digestion and absorption     5322 (PLA2G5)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:hsa03036]     5322 (PLA2G5) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      5322 (PLA2G5) Chromosome and associated proteins [BR:hsa03036]  Eukaryotic type   Centrosome formation proteins    Centriole proteins     5322 (PLA2G5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Phospholip_A2_1 Phospholip_A2_2 Motif Other DBs NCBI-GeneID:  5322 NCBI-ProteinID:  NP_000920 OMIM:  601192 HGNC:  9038 Ensembl:  ENSG00000127472 Pharos:  P39877(Tchem) UniProt:  P39877 LinkDB All DBs Position 1:20028408..20091911 Genome browser AA seq 138 aa AA seqDB search MKGLLPLAWFLACSVPAVQGGLLDLKSMIEKVTGKNALTNYGFYGCYCGWGGRGTPKDGT DWCCWAHDHCYGRLEEKGCNIRTQSYKYRFAWGVVTCEPGPFCHVNLCACDRKLVYCLKR NLRSYNPQYQYFPNILCS NT seq 417 nt NT seq  +upstreamnt  +downstreamnt atgaaaggcctcctcccactggcttggttcctggcttgtagtgtgcctgctgtgcaagga ggcttgctggacctaaaatcaatgatcgagaaggtgacagggaagaacgccctgacaaac tacggcttctacggctgttactgcggctggggcggccgaggaacccccaaggatggcacc gattggtgctgttgggcgcatgaccactgctatgggcggctggaggagaagggctgcaac attcgcacacagtcctacaaatacagattcgcgtggggcgtggtcacctgcgagcccggg cccttctgccatgtgaacctctgtgcctgtgaccggaagctcgtctactgcctcaagaga aacctacggagctacaacccacagtaccaatactttcccaacatcctctgctcctag

Homo sapiens (human): 5406 Help Entry 5406              CDS       T01001                                  Symbol PNLIP, PL, PNLIPD, PTL Name (RefSeq) pancreatic lipase   KO K14073   pancreatic triacylglycerol lipase [EC:3.1.1.3] Organism hsa  Homo sapiens (human) Pathway hsa00561   Glycerolipid metabolism hsa01100   Metabolic pathways hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption hsa04977   Vitamin digestion and absorption Module hsa_M00098   Acylglycerol degradation Disease H02330   Pancreatic lipase deficiency Drug target Cetilistat:  D09208<JP> Orlistat:  D04028<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00561 Glycerolipid metabolism     5406 (PNLIP)  09150 Organismal Systems   09154 Digestive system    04972 Pancreatic secretion     5406 (PNLIP)    04975 Fat digestion and absorption     5406 (PNLIP)    04977 Vitamin digestion and absorption     5406 (PNLIP) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.3  triacylglycerol lipase      5406 (PNLIP) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipase PLAT Abhydrolase_6 Hydrolase_4 Abhydrolase_1 Motif Other DBs NCBI-GeneID:  5406 NCBI-ProteinID:  NP_000927 OMIM:  246600 HGNC:  9155 Ensembl:  ENSG00000175535 Pharos:  P16233(Tclin) UniProt:  P16233 Structure PDB LinkDB All DBs Position 10:116545931..116567855 Genome browser AA seq 465 aa AA seqDB search MLPLWTLSLLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTN ENPNNFQEVAADSSSISGSNFKTNRKTRFIIHGFIDKGEENWLANVCKNLFKVESVNCIC VDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGR RTNGTIGRITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGH LDFFPNGGVEMPGCKKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPDGFAGF PCASYNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVS VTLSGKKVTGHILVSLFGNKGNSKQYEIFKGTLKPDSTHSNEFDSDVDVGDLQMVKFIWY NNVINPTLPRVGASKIIVETNVGKQFNFCSPETVREEVLLTLTPC NT seq 1398 nt NT seq  +upstreamnt  +downstreamnt atgctgccactttggactctttcactgctgctgggagcagtagcaggaaaagaagtttgc tacgaaagactcggctgcttcagtgatgactccccatggtcaggaattacggaaagaccc ctccatatattgccttggtctccaaaagatgtcaacacccgcttcctcctatatactaat gagaacccaaacaactttcaagaagttgccgcagattcatcaagcatcagtggctccaat ttcaaaacaaatagaaaaactcgctttattattcatggattcatagacaagggagaagaa aactggctggccaatgtgtgcaagaatctgttcaaggtggaaagtgtgaactgtatctgt gtggactggaaaggtggctcccgaactggatacacacaagcctcgcagaacatcaggatc gtgggagcagaagtggcatattttgttgaatttcttcagtcggcgttcggttactcacct tccaatgtgcatgtcattggccacagcctgggtgcccacgctgctggggaggctggaagg agaaccaatgggaccattggacgcatcacagggttggacccagcagaaccttgctttcag ggcacacctgaattagtccgattggaccccagcgatgccaaatttgtggatgtaattcac acggatggtgcccccatagtccccaatttggggtttggaatgagccaagtcgtgggccac ctagatttctttccaaatggaggagtggaaatgcctggatgtaaaaagaacattctctct cagattgtggacatagacggaatctgggaagggactcgagactttgcggcctgtaatcac ttaagaagctacaaatattacactgatagcatcgtcaaccctgatggctttgctggattc ccctgtgcctcttacaacgtcttcactgcaaacaagtgtttcccttgtccaagtggaggc tgcccacagatgggtcactatgctgatagatatcctgggaaaacaaatgatgtgggccag aaattttatctagacactggtgatgccagtaattttgcacgttggaggtataaggtatct gtcacactgtctggaaaaaaggttacaggacacatactagtttctttgttcggaaataaa ggaaactctaagcagtatgaaattttcaagggcactctcaaaccagatagtactcattcc aatgaatttgactcagatgtggatgttggggacttgcagatggttaaatttatttggtat aacaatgtgatcaacccaactttacctagagtgggagcatccaagattatagtggagaca aatgttggaaaacagttcaacttctgtagtccagaaaccgtcagggaggaagttctgctc accctcacaccgtgttag

Homo sapiens (human): 5407 Help Entry 5407              CDS       T01001                                  Symbol PNLIPRP1, PLRP1 Name (RefSeq) pancreatic lipase related protein 1   KO K14074   pancreatic lipase-related protein 1 [EC:3.1.1.3] Organism hsa  Homo sapiens (human) Pathway hsa00561   Glycerolipid metabolism hsa01100   Metabolic pathways hsa04972   Pancreatic secretion hsa04975   Fat digestion and absorption Module hsa_M00098   Acylglycerol degradation Drug target Orlistat:  D04028<US> Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00561 Glycerolipid metabolism     5407 (PNLIPRP1)  09150 Organismal Systems   09154 Digestive system    04972 Pancreatic secretion     5407 (PNLIPRP1)    04975 Fat digestion and absorption     5407 (PNLIPRP1) Enzymes [BR:hsa01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.3  triacylglycerol lipase      5407 (PNLIPRP1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Lipase PLAT Abhydrolase_6 Palm_thioest Abhydrolase_3 Abhydrolase_1 Lipase_3 LIDHydrolase DUF900 DUF676 Hydrolase_4 Motif Other DBs NCBI-GeneID:  5407 NCBI-ProteinID:  NP_001290064 OMIM:  604422 HGNC:  9156 Ensembl:  ENSG00000187021 Pharos:  P54315(Tbio) UniProt:  P54315 Structure PDB LinkDB All DBs Position 10:116590959..116609175 Genome browser AA seq 467 aa AA seqDB search MLIFWTITLFLLGAAKGKEVCYEDLGCFSDTEPWGGTAIRPLKILPWSPEKIGTRFLLYT NENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKKLFEVEEVNC ICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEA GSKTPGLSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMG HLDFFPNGGESMPGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESILNPDGFAA YPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFFLNTGEASNFARWRYGV SITLSGRTATGQIKVALFGNKGNTHQYSIFRGILKPGSTHSYEFDAKLDVGTIEKVKFLW NNNVINPTLPKVGATKITVQKGEEKTVYNFCSEDTVREDTLLTLTPC NT seq 1404 nt NT seq  +upstreamnt  +downstreamnt atgctgatcttctggacaatcacacttttcctgctgggagcagccaaaggaaaagaagtt tgctatgaggacctcgggtgcttttctgacactgagccctggggcgggacagcaatcagg cccctgaaaattctcccctggagccctgagaagatcggcacccgcttcctgctgtacacc aatgaaaacccaaacaactttcaaattctcctcctctctgatccatcaacaattgaggca tcaaattttcaaatggacagaaagacccggttcatcatccatggcttcatagacaaagga gatgagagctgggtgacagacatgtgcaagaaactgttcgaggtggaggaggtgaactgc atctgcgtggactggaagaagggctcccaagccacctacacacaggctgccaacaacgtg cgagtggtgggcgcccaggtggcccagatgctcgacatcctcttgacagagtatagctac cccccttccaaagttcacctcattggccacagcctgggagcccacgtggctggagaggca ggaagcaagactccaggcctgagcaggattacagggttggatcctgtagaagcaagtttc gagagtactcctgaagaggtgcgacttgatccctctgatgctgactttgttgatgtgatt cacacggatgcagctcccctgatcccattcttgggttttggaacgaaccaacagatgggt catcttgacttcttccccaatggaggagagagcatgccgggatgcaagaagaatgccctg tctcagatcgtggatctagatggcatctgggcgggaacccgggactttgtggcttgcaat cacctaagaagctacaagtattacttggaaagcatcctcaatcccgatgggtttgctgca tatccctgcacttcctacaagtcctttgagtctgacaagtgcttcccgtgtccagatcaa ggatgcccacagatgggtcactatgctgataaatttgctggcaggacaagtgaagagcag cagaaattcttcttgaacacaggagaggctagcaatttcgctcgctggagatatggggtt tccatcacactgtctggaagaacagccactggtcagatcaaagttgctttgtttggaaat aagggaaacactcaccagtacagtatcttcagggggattctcaaaccaggctcaacccat tcctatgagtttgatgcaaagctggatgttggaacaattgagaaagtcaagtttctttgg aataacaatgtgataaatccaaccctccccaaagtgggtgccaccaagatcactgtgcaa aagggagaagagaagacagtgtacaacttctgtagcgaagacacagtgcgggaagacacg ctgctcaccctcacgccctgctaa

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