Homo sapiens (human): 10825 Help Entry 10825             CDS       T01001                                  Symbol NEU3, SIAL3 Name (RefSeq) neuraminidase 3   KO K12357   sialidase-2/3/4 [EC:3.2.1.18] Organism hsa  Homo sapiens (human) Pathway hsa00511   Other glycan degradation hsa00600   Sphingolipid metabolism hsa01100   Metabolic pathways Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     10825 (NEU3)   09107 Glycan biosynthesis and metabolism    00511 Other glycan degradation     10825 (NEU3) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.18  exo-alpha-sialidase      10825 (NEU3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  BNR_2 BNR_3 BNR Motif Other DBs NCBI-GeneID:  10825 NCBI-ProteinID:  NP_006647 OMIM:  604617 HGNC:  7760 Ensembl:  ENSG00000162139 Pharos:  Q9UQ49(Tbio) UniProt:  Q9UQ49 A0A024R5N6 LinkDB All DBs Position 11:74980515..75020676 Genome browser AA seq 461 aa AA seqDB search MRPADLPPRPMEESPASSSAPTETEEPGSSAEVMEEVTTCSFNSPLFRQEDDRGITYRIP ALLYIPPTHTFLAFAEKRSTRRDEDALHLVLRRGLRIGQLVQWGPLKPLMEATLPGHRTM NPCPVWEQKSGCVFLFFICVRGHVTERQQIVSGRNAARLCFIYSQDAGCSWSEVRDLTEE VIGSELKHWATFAVGPGHGIQLQSGRLVIPAYTYYIPSWFFCFQLPCKTRPHSLMIYSDD LGVTWHHGRLIRPMVTVECEVAEVTGRAGHPVLYCSARTPNRCRAEALSTDHGEGFQRLA LSRQLCEPPHGCQGSVVSFRPLEIPHRCQDSSSKDAPTIQQSSPGSSLRLEEEAGTPSES WLLYSHPTSRKQRVDLGIYLNQTPLEAACWSRPWILHCGPCGYSDLAALEEEGLFGCLFE CGTKQECEQIAFRLFTHREILSHLQGDCTSPGRNPSQFKSN NT seq 1386 nt NT seq  +upstreamnt  +downstreamnt atgagacctgcggacctgcccccgcgccccatggaagaatccccggcgtccagctctgcc ccgacagagacggaggagccggggtccagtgcagaggtcatggaagaagtgacaacatgc tccttcaacagccctctgttccggcaggaagatgacagagggattacctaccggatccca gccctgctctacataccccccacccacaccttcctggcctttgcagagaagcgttctacg aggagagatgaggatgctctccacctggtgctgaggcgagggttgaggattgggcagttg gtacagtgggggcccctgaagccactgatggaagccacactaccggggcatcggaccatg aacccctgtcctgtatgggagcagaagagtggttgtgtgttcctgttcttcatctgtgtg cggggccatgtcacagagcgtcaacagattgtgtcaggcaggaatgctgcccgcctttgc ttcatctacagtcaggatgctggatgttcatggagtgaggtgagggacttgactgaggag gtcattggctcagagctgaagcactgggccacatttgctgtgggcccaggtcatggcatc cagctgcagtcagggagactggtcatccctgcgtatacctactacatcccttcctggttc ttttgcttccagctaccatgtaaaaccaggcctcattctctgatgatctacagtgatgac ctaggggtcacatggcaccatggtagactcattaggcccatggttacagtagaatgtgaa gtggcagaggtgactgggagggctggccaccctgtgctatattgcagtgcccggacacca aacaggtgccgggcagaggcgctcagcactgaccatggtgaaggctttcagagactggcc ctgagtcgacagctctgtgagcccccacatggttgccaagggagtgtggtaagtttccgg cccctggagatcccacataggtgccaggactctagcagcaaagatgcacccaccattcag cagagctctccaggcagttcactgaggctggaggaggaagctggaacaccgtcagaatca tggctcttgtactcacacccaaccagtaggaaacagagggttgacctaggtatctatctc aaccagacccccttggaggctgcctgctggtcccgcccctggatcttgcactgtgggccc tgtggctactctgatctggctgctctggaggaggagggcttgtttgggtgtttgtttgaa tgtgggaccaagcaagagtgtgagcagattgccttccgcctgtttacacaccgggagatc ctgagtcacctgcagggggactgcaccagccctggtaggaacccaagccaattcaaaagc aattaa

Homo sapiens (human): 129807 Help Entry 129807            CDS       T01001                                  Symbol NEU4 Name (RefSeq) neuraminidase 4   KO K12357   sialidase-2/3/4 [EC:3.2.1.18] Organism hsa  Homo sapiens (human) Pathway hsa00511   Other glycan degradation hsa00600   Sphingolipid metabolism hsa01100   Metabolic pathways Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     129807 (NEU4)   09107 Glycan biosynthesis and metabolism    00511 Other glycan degradation     129807 (NEU4) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.18  exo-alpha-sialidase      129807 (NEU4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  BNR_2 BNR_3 BNR Motif Other DBs NCBI-GeneID:  129807 NCBI-ProteinID:  NP_001161072 OMIM:  608527 HGNC:  21328 Ensembl:  ENSG00000204099 Pharos:  Q8WWR8(Tchem) UniProt:  Q8WWR8 B3KR54 LinkDB All DBs Position 2:241809193..241817413 Genome browser AA seq 484 aa AA seqDB search MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGT LAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRN AARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYR VDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCN ARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGP GSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSW TLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYS DLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGC CWPS NT seq 1455 nt NT seq  +upstreamnt  +downstreamnt atgggggtccctcgtaccccttcacggacagtgctcttcgagcgggagaggacgggcctg acctaccgcgtgccctcgctgctccccgtgccccccgggcccaccctgctggcctttgtg gagcagcggctcagccctgacgactcccacgcccaccgcctggtgctgaggaggggcacg ctggccgggggctccgtgcggtggggtgccctgcacgtgctggggacagcagccctggcg gagcaccggtccatgaacccctgccctgtgcacgatgctggcacgggcaccgtcttcctc ttcttcatcgcggtgctgggccacacgcctgaggccgtgcagatcgccacgggaaggaac gccgcgcgcctctgctgtgtggccagccgtgacgccggcctctcgtggggcagcgcccgg gacctcaccgaggaggccatcggtggtgccgtgcaggactgggccacattcgctgtgggt cccggccacggtgtgcagctgccctcaggccgcctgctggtacccgcctacacctaccgc gtggaccgccgagagtgttttggcaagatctgccggaccagccctcactccttcgccttc tacagcgatgaccacggccgcacctggcgctgtggaggcctcgtgcccaacctgcgctca ggcgagtgccagctggcagcggtggacggtgggcaggccggcagcttcctctactgcaat gcccggagcccactgggcagccgtgtgcaggcgctcagcactgacgagggcacctccttc ctgcccgcagagcgcgtggcttccctgcccgagactgcctggggctgccagggcagcatc gtgggcttcccagcccccgcccccaacaggccacgggatgacagttggtcagtgggcccc gggagtcccctccagcctccactcctcggtcctggagtccacgaacccccagaggaggct gctgtagacccccgtggaggccaggtgcctggtgggcccttcagccgtctgcagcctcgg ggggatggccccaggcagcctggccccaggcctggggtcagtggggatgtggggtcctgg accctggcactccccatgccctttgctgccccgccccagagccccacgtggctgctgtac tcccacccagtggggcgcagggctcggctacacatgggtatccgcctgagccagtccccg ctggacccgcgcagctggacagagccctgggtgatctacgagggccccagcggctactcc gacctggcgtccatcgggccggcccctgaggggggcctggtttttgcctgcctgtacgag agcggggccaggacctcctatgatgagatttccttttgtacattctccctgcgtgaggtc ctggagaacgtgcccgccagccccaaaccgcccaaccttggggacaagcctcgggggtgc tgctggccctcctga

Homo sapiens (human): 4758 Help Entry 4758              CDS       T01001                                  Symbol NEU1, NANH, NEU, SIAL1 Name (RefSeq) neuraminidase 1   KO K01186   sialidase-1 [EC:3.2.1.18] Organism hsa  Homo sapiens (human) Pathway hsa00511   Other glycan degradation hsa00600   Sphingolipid metabolism hsa01100   Metabolic pathways hsa04142   Lysosome Disease H00142   Sialidosis H00422   Glycoproteinoses Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     4758 (NEU1)   09107 Glycan biosynthesis and metabolism    00511 Other glycan degradation     4758 (NEU1)  09140 Cellular Processes   09141 Transport and catabolism    04142 Lysosome     4758 (NEU1) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.18  exo-alpha-sialidase      4758 (NEU1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  BNR_2 BNR_3 MupG_C Motif Other DBs NCBI-GeneID:  4758 NCBI-ProteinID:  NP_000425 OMIM:  608272 HGNC:  7758 Ensembl:  ENSG00000204386 Pharos:  Q99519(Tbio) UniProt:  Q99519 Q5JQI0 LinkDB All DBs Position 6:complement(31857659..31862821) Genome browser AA seq 415 aa AA seqDB search MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTM EQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGST WSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVS WSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASW RYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACD TLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKET VQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL NT seq 1248 nt NT seq  +upstreamnt  +downstreamnt atgactggggagcgacccagcacggcgctcccggacagacgctgggggccgcggattctg ggcttctggggaggctgtagggtttgggtgtttgccgcgatcttcctgctgctgtctctg gcagcctcctggtccaaggctgagaacgacttcggtctggtgcagccgctggtgaccatg gagcaactgctgtgggtgagcgggagacagatcggctcagtggacaccttccgcatcccg ctcatcacagccactccgcggggcactcttctcgcctttgctgaggcgaggaaaatgtcc tcatccgatgagggggccaagttcatcgccctgcggaggtccatggaccagggcagcaca tggtctcctacagcgttcattgtcaatgatggggatgtccccgatgggctgaaccttggg gcagtagtgagcgatgttgagacaggagtagtatttcttttctactccctttgtgctcac aaggccggctgccaggtggcctctaccatgttggtatggagcaaggatgatggtgtttcc tggagcacaccccggaatctctccctggatattggcactgaagtgtttgcccctggaccg ggctctggtattcagaaacagcgggagccacggaagggccgcctcatcgtgtgtggccat gggacgctggagcgggacggagtcttctgtctcctcagcgatgatcatggtgcctcctgg cgctacggaagtggggtcagcggcatcccctacggtcagcccaagcaggaaaatgatttc aatcctgatgaatgccagccctatgagctcccagatggctcagtcgtcatcaatgcccga aaccagaacaactaccactgccactgccgaattgtcctccgcagctatgatgcctgtgat acactaaggccccgtgatgtgaccttcgaccctgagctcgtggaccctgtggtagctgca ggagctgtagtcaccagctccggcattgtcttcttctccaacccagcacatccagagttc cgagtgaacctgaccctgcgatggagcttcagcaatggtacctcatggcggaaagagaca gtccagctatggccaggccccagtggctattcatccctggcaaccctggagggcagcatg gatggagaggagcaggccccccagctctacgtcctgtatgagaaaggccggaaccactac acagagagcatctccgtggccaaaatcagtgtctatgggacactctga

Homo sapiens (human): 4759 Help Entry 4759              CDS       T01001                                  Symbol NEU2, SIAL2 Name (RefSeq) neuraminidase 2   KO K12357   sialidase-2/3/4 [EC:3.2.1.18] Organism hsa  Homo sapiens (human) Pathway hsa00511   Other glycan degradation hsa00600   Sphingolipid metabolism hsa01100   Metabolic pathways Brite KEGG Orthology (KO) [BR:hsa00001]  09100 Metabolism   09103 Lipid metabolism    00600 Sphingolipid metabolism     4759 (NEU2)   09107 Glycan biosynthesis and metabolism    00511 Other glycan degradation     4759 (NEU2) Enzymes [BR:hsa01000]  3. Hydrolases   3.2  Glycosylases    3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds     3.2.1.18  exo-alpha-sialidase      4759 (NEU2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  BNR_2 BNR_3 BNR Motif Other DBs NCBI-GeneID:  4759 NCBI-ProteinID:  NP_005374 OMIM:  605528 HGNC:  7759 Ensembl:  ENSG00000115488 Pharos:  Q9Y3R4(Tbio) UniProt:  Q9Y3R4 Structure PDB LinkDB All DBs Position 2:233032672..233035057 Genome browser AA seq 380 aa AA seqDB search MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYD APTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRAN VTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYA YRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHL RARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTH SWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYE EIVFLMFTLKQAFPAEYLPQ NT seq 1143 nt NT seq  +upstreamnt  +downstreamnt atggcgtcccttcctgtcctgcagaaggagagcgtgttccagtcgggagcccatgcctac agaatccctgccctgctctacctgcctgggcagcagtccctgctggccttcgcggaacag cgggcaagcaagaaggatgagcacgcagagctgattgtcctgcgcagaggagactacgac gcacccacccaccaggttcagtggcaagctcaggaggtggtggcccaggcccggctggat ggccaccggtccatgaacccatgccccttgtatgacgcgcagacggggaccctcttcctc ttcttcattgccatccctgggcaagtcacggagcaacagcagctgcagaccagggccaat gtgacgcggctgtgccaagtcaccagcactgaccacgggaggacctggagctcccccaga gacctcactgatgcggccatcggcccagcctaccgggagtggtccacctttgcagtgggc ccggggcattgtttgcagcttcacgacagggcccggagcctggtggtgcccgcctacgcc taccggaaacttcaccccatccaaaggccgatcccctctgccttctgcttcctcagccat gaccatgggcgcacgtgggcgcgagggcactttgtggcccaggacaccctggagtgccag gtggccgaagtcgagactggggagcagagggtggtgaccctcaacgcgagaagccacctc cgagccagggtccaggcccagagcaccaatgacgggcttgatttccaggagtctcagctg gtgaagaagctggtggagccgccgccccagggctgccaggggagcgtcatcagcttcccc agcccccgctcggggcctggctccccagcccagtggctgctctacactcaccccacacac tcctggcagagggccgacctgggtgcctacctcaacccgcgacctccagcccctgaggcc tggtcagagccggtactgctggccaagggcagctgtgcctactcagacctccagagcatg ggcaccggccctgatgggtcccccttgtttgggtgtctgtacgaagccaatgattacgag gagattgtctttctcatgttcaccctgaagcaagccttcccagctgagtacctgcctcag tga

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