KEGG   Homo sapiens (human): 10975
Entry
10975             CDS       T01001                                 
Symbol
UQCR11, 0710008D09Rik, QCR10, UQCR
Name
(RefSeq) ubiquinol-cytochrome c reductase, complex III subunit XI
  KO
K00420  ubiquinol-cytochrome c reductase subunit 10
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04260  Cardiac muscle contraction
hsa04714  Thermogenesis
hsa04932  Non-alcoholic fatty liver disease
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05415  Diabetic cardiomyopathy
Module
hsa_M00152  Cytochrome bc1 complex
Network
nt06252  Mitochondrial ROS formation (cancer)
nt06461  Huntington disease
nt06463  Parkinson disease
nt06466  Pathways of neurodegeneration
  Element
N00990  Electron transfer in Complex III
N00991  Mutation-caused aberrant Htt to electron transfer in Complex III
N01046  Maneb to electron transfer in Complex III
N01395  Cadmium to electron transfer in complex III
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    10975 (UQCR11)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    10975 (UQCR11)
  09159 Environmental adaptation
   04714 Thermogenesis
    10975 (UQCR11)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    10975 (UQCR11)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    10975 (UQCR11)
   05012 Parkinson disease
    10975 (UQCR11)
   05014 Amyotrophic lateral sclerosis
    10975 (UQCR11)
   05016 Huntington disease
    10975 (UQCR11)
   05020 Prion disease
    10975 (UQCR11)
   05022 Pathways of neurodegeneration - multiple diseases
    10975 (UQCR11)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    10975 (UQCR11)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    10975 (UQCR11)
SSDB
Motif
Pfam: UCR_6-4kD QCR10
Other DBs
NCBI-GeneID: 10975
NCBI-ProteinID: NP_006821
OMIM: 609711
HGNC: 30862
Ensembl: ENSG00000127540
Pharos: O14957(Tdark)
UniProt: O14957
Structure
LinkDB
Position
19:complement(1597169..1605462)
AA seq 56 aa
MVTRFLGPRYRELVKNWVPTAYTWGAVGAVGLVWATDWRLILDWVPYINGKFKKDN
NT seq 171 nt   +upstreamnt  +downstreamnt
atggtgacccggttcctgggcccacgctaccgggagctggtcaagaactgggtcccgacg
gcctacacatggggcgctgtgggcgccgtggggctggtgtgggccaccgattggcggctg
atcctggactgggtaccttacatcaatggcaagtttaagaaggataattaa

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