Homo sapiens (human): 1138
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Entry
1138 CDS
T01001
Symbol
CHRNA5, LNCR2
Name
(RefSeq) neuronal acetylcholine receptor subunit alpha-5 isoform 1 precursor
KO
K04807
nicotinic acetylcholine receptor alpha-5
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
Drug target
Acetylcholine (
DG01133
):
D00999
<JP/US>
Atracurium (
DG00771
):
D00758
<US>
Cisatracurium:
D00759
<US>
Cytisinicline:
D07770
Dimethyltubocurarine:
D07272
Doxacurium chloride:
D00760
Fazadinium bromide:
D07273
Hexamethonium bromide:
D02204
Lobeline (
DG01287
):
D02202
D02364
D08138
Mecamylamine (
DG00252
):
D00611
<US>
Mivacurium chloride:
D00763
Nicotine (
DG00994
):
D03365
<JP/US>
D05156
D05157
Pancuronium (
DG00769
):
D00492
Pipecuronium bromide:
D00764
Rocuronium bromide:
D00765
<JP/US>
Tubocurarine (
DG00767
):
D02207
D08655
Vecuronium (
DG00770
):
D00767
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
1138 (CHRNA5)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
1138 (CHRNA5)
Ion channels [BR:
hsa04040
]
Ligand-gated channels
Acetylcholine (nicotinic)
1138 (CHRNA5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Neur_chan_LBD
Neur_chan_memb
Cadherin_5
Motif
Other DBs
NCBI-GeneID:
1138
NCBI-ProteinID:
NP_000736
OMIM:
118505
HGNC:
1959
Ensembl:
ENSP00000299565.5
UniProt:
P30532
Q6EWN4
LinkDB
All DBs
Position
15:78565520..78595269
Genome browser
AA seq
468 aa
AA seq
DB search
MAARGSGPRALRLLLLVQLVAGRCGLAGAAGGAQRGLSEPSSIAKHEDSLLKDLFQDYER
WVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDYGGIKV
IRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTIDVTFFPFD
LQNCSMKFGSWTYDGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYV
TYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEGEKICLCTSVLVSLTVFLLVIE
EIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAMAPLVRKIFLHTL
PKLLCMRSHVDRYFTQKEETESGSGPKSSRNTLEAALDSIRYITRHIMKENDVREVVEDW
KFIAQVLDRMFLWTFLFVSIVGSLGLFVPVIYKWANILIPVHIGNANK
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgcgggggtcagggccccgcgcgctccgcctgctgctcttggtccagctggtc
gcggggcgctgcggtctagcgggcgcggcgggcggcgcgcagagaggattatctgaacct
tcttctattgcaaaacatgaagatagtttgcttaaggatttatttcaagactacgaaaga
tgggttcgtcctgtggaacacctgaatgacaaaataaaaataaaatttggacttgcaata
tctcaattggtggatgtggatgagaaaaatcagttaatgacaacaaacgtctggttgaaa
caggaatggatagatgtaaaattaagatggaaccctgatgactatggtggaataaaagtt
atacgtgttccttcagactctgtctggacaccagacatcgttttgtttgataatgcagat
ggacgttttgaagggaccagtacgaaaacagtcatcaggtacaatggcactgtcacctgg
actccaccggcaaactacaaaagttcctgtaccatagatgtcacgtttttcccatttgac
cttcagaactgttccatgaaatttggttcttggacttatgatggatcacaggttgatata
attctagaggaccaagatgtagacaagagagatttttttgataatggagaatgggagatt
gtgagtgcaacagggagcaaaggaaacagaaccgacagctgttgctggtatccgtatgtc
acttactcatttgtaatcaagcgcctgcctctcttttataccttgttccttataataccc
tgtattgggctctcatttttaactgtacttgtcttctatcttccttcaaatgaaggtgaa
aagatttgtctctgcacttcagtacttgtgtctttgactgtcttccttctggttattgaa
gagatcataccatcatcttcaaaagtcatacctctaattggagagtatctggtatttacc
atgatttttgtgacactgtcaattatggtaaccgtcttcgctatcaacattcatcatcgt
tcttcctcaacacataatgccatggcgcctttggtccgcaagatatttcttcacacgctt
cccaaactgctttgcatgagaagtcatgtagacaggtacttcactcagaaagaggaaact
gagagtggtagtggaccaaaatcttctagaaacacattggaagctgcgctcgattctatt
cgctacattacaagacacatcatgaaggaaaatgatgtccgtgaggttgttgaagattgg
aaattcatagcccaggttcttgatcggatgtttctgtggacttttcttttcgtttcaatt
gttggatctcttgggctttttgttcctgttatttataaatgggcaaatatattaatacca
gttcatattggaaatgcaaataagtga
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