Homo sapiens (human): 116085
Help
Entry
116085 CDS
T01001
Symbol
SLC22A12, OAT4L, RST, UAT, URAT1, hURAT1
Name
(RefSeq) solute carrier family 22 member 12
KO
K08208
MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 12
Organism
hsa
Homo sapiens (human)
Disease
H00948
Renal hypouricemia
Drug target
Benzbromarone:
D01056
<JP>
Lesinurad (
DG01388
):
D09921
D09922
Verinurad:
D11129
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
116085 (SLC22A12)
04147 Exosome [BR:
hsa04147
]
116085 (SLC22A12)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC22: Organic cation/anion/zwitterion transporter
116085 (SLC22A12)
Major facilitator superfamily (MFS)
Organic acid transporters
Organic cation transporter (OCT) family [TC:
2.A.1.19
]
116085 (SLC22A12)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
116085 (SLC22A12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MFS_1
Sugar_tr
Motif
Other DBs
NCBI-GeneID:
116085
NCBI-ProteinID:
NP_653186
OMIM:
607096
HGNC:
17989
Ensembl:
ENSG00000197891
Pharos:
Q96S37
(Tclin)
UniProt:
Q96S37
LinkDB
All DBs
Position
11:64591220..64602344
Genome browser
AA seq
553 aa
AA seq
DB search
MAFSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAPLLDNSTAQ
ASILGSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATATSWSEADTEPCVDGW
VYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILVGAAACGPASDRFGRRLVLTWSY
LQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLG
FSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFLYSWWLAESARWLLTTGRLDWGLQELW
RVAAINGKGAVQDTLTPEVLLSAMREELSMGQPPASLGTLLRMPGLRFRTCISTLCWFAF
GFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRRPTLAASLLLAGLCI
LANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTVLRMTAVGLGQMAARGGA
ILGPLVRLLGVHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLPDTIQDVQNQAVKKATH
GTLGNSVLKSTQF
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atggcattttctgaactcctggacctcgtgggtggcctgggcaggttccaggttctccag
acgatggctctgatggtctccatcatgtggctgtgtacccagagcatgctggagaacttc
tcggccgccgtgcccagccaccgctgctgggcacccctcctggacaacagcacggctcag
gccagcatcctagggagcttgagtcctgaggccctcctggctatttccatcccgccgggc
cccaaccagaggccccaccagtgccgccgcttccgccagccacagtggcagctcttggac
cccaatgccacggccaccagctggagcgaggccgacacggagccgtgtgtggatggctgg
gtctatgaccgcagcatcttcacctccacaatcgtggccaagtggaacctcgtgtgtgac
tctcatgctctgaagcccatggcccagtccatctacctggctgggattctggtgggagct
gctgcgtgcggccctgcctcagacaggtttgggcgcaggctggtgctaacctggagctac
cttcagatggctgtgatgggtacggcagctgccttcgcccctgccttccccgtgtactgc
ctgttccgcttcctgttggcctttgccgtggcaggcgtcatgatgaacacgggcactctc
ctgatggagtggacggcggcacgggcccgacccttggtgatgaccttgaactctctgggc
ttcagcttcggccatggcctgacagctgcagtggcctacggtgtgcgggactggacactg
ctgcagctggtggtctcggtccccttcttcctctgctttttgtactcctggtggctggca
gagtcggcacgatggctcctcaccacaggcaggctggattggggcctgcaggagctgtgg
agggtggctgccatcaacggaaagggggcagtgcaggacaccctgacccctgaggtcttg
ctttcagccatgcgggaggagctgagcatgggccagcctcctgccagcctgggcaccctg
ctccgcatgcccggactgcgcttccggacctgtatctccacgttgtgctggttcgccttt
ggcttcaccttcttcggcctggccctggacctgcaggccctgggcagcaacatcttcctg
ctccaaatgttcattggtgtcgtggacatcccagccaagatgggcgccctgctgctgctg
agccacctgggccgccgccccacgctggccgcatccctgttgctggcagggctctgcatt
ctggccaacacgctggtgccccacgaaatgggggctctgcgctcagccttggccgtgctg
gggctgggcggggtgggggctgccttcacctgcatcaccatctacagcagcgagctcttc
cccactgtgctcaggatgacggcagtgggcttgggccagatggcagcccgtggaggagcc
atcctggggcctctggtccggctgctgggtgtccatggcccctggctgcccttgctggtg
tatgggacggtgccagtgctgagtggcctggccgcactgcttctgcccgagacccagagc
ttgccgctgcccgacaccatccaagatgtgcagaaccaggcagtaaagaaggcaacacat
ggcacgctggggaactctgtcctaaaatccacacagttttag
DBGET
integrated database retrieval system
