Homo sapiens (human): 122042 Help Entry 122042            CDS       T01001                                  Symbol RXFP2, GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2 Name (RefSeq) relaxin family peptide receptor 2   KO K04307   relaxin family peptide receptor 2 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04926   Relaxin signaling pathway Drug target Volenrelaxin:  D12783 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     122042 (RXFP2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     122042 (RXFP2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     122042 (RXFP2) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Relaxin     122042 (RXFP2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 7tm_1 LRR_5 LRR_4 Ldl_recept_a LRR_9 LRR_1 Motif Other DBs NCBI-GeneID:  122042 NCBI-ProteinID:  NP_570718 OMIM:  606655 HGNC:  17318 Ensembl:  ENSG00000133105 UniProt:  Q8WXD0 Structure PDBPDBj LinkDB All DBs Position 13:31739526..31803389 Genome browser AA seq 754 aa AA seqDB search MIVFLVFKHLFSLRLITMFFLLHFIVLINVKDFALTQGSMITPSCQKGYFPCGNLTKCLP RAFHCDGKDDCGNGADEENCGDTSGWATIFGTVHGNANSVALTQECFLKQYPQCCDCKET ELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKA FFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSM VNNYLEALPKQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKT FSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDL ERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRI FVWVIAFITCFGNLFVIGMRSFIKAENTTHAMSIKILCCADCLMGVYLFFVGIFDIKYRG QYQKYALLWMESVQCRLMGFLAMLSTEVSVLLLTYLTLEKFLVIVFPFSNIRPGKRQTSV ILICIWMAGFLIAVIPFWNKDYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLL AFLIIVFSYITMFCSIQKTALQTTEVRNCFGREVAVANRFFFIVFSDAICWIPVFVVKIL SLFRVEIPDTMTSWIVIFFLPVNSALNPILYTLTTNFFKDKLKQLLHKHQRKSIFKIKKK SLSTSIVWIEDSSSLKLGVLNKITLGDSIMKPVS NT seq 2265 nt NT seq  +upstreamnt  +downstreamnt atgattgtttttctggtttttaaacatctcttcagcctcagattgattacaatgttcttt ctacttcatttcatcgttctgatcaatgtcaaagattttgcactgactcaaggtagcatg atcactccttcatgccaaaaaggatattttccctgtgggaatcttaccaagtgcttaccc cgagcttttcactgtgatggcaaggatgactgtgggaacggggcggacgaagagaactgt ggtgacactagtggatgggcgaccatatttggcacagtgcatggaaatgctaacagcgtg gccttaacacaggagtgctttctaaaacagtatccacaatgctgtgactgcaaagaaact gaattggaatgtgtaaatggtgacttaaagtctgtgccgatgatttctaacaatgtgaca ttactgtctcttaagaaaaacaaaatccacagtcttccagataaagttttcatcaaatac acaaaacttaaaaagatatttcttcagcataattgcattagacacatatccaggaaagca ttttttggattatgtaatctgcaaatattatatctcaaccacaactgcatcacaaccctc agacctggaatattcaaagacttacatcagctaacttggctaattctagatgacaatcca ataaccagaatttcacagcgcttgtttacgggattaaattccttgtttttcctgtctatg gttaataactacttagaagctcttcccaagcagatgtgtgcccaaatgcctcaactcaac tgggtggatttggaaggcaatagaataaagtatctcacaaattctacgtttctgtcgtgc gattcgctcacagtgctgtttctgcctagaaatcaaattggttttgttccagagaagaca ttttcttcattaaaaaatttaggagaactggatctgtctagcaatacgataacggaacta tcacctcacctttttaaagacttgaagcttctacaaaagctgaacctgtcatccaatcct cttatgtatcttcacaagaaccagtttgaaagtcttaaacaacttcagtctctagacctg gaaaggatagagattccaaatataaacacacgaatgtttcaacccatgaagaatctttct cacatttatttcaaaaactttcgatactgctcctatgctccccatgtccgaatatgtatg cccttgacggacggcatttcttcatttgaggacctcttggctaacaatatcctcagaata tttgtctgggttatagctttcattacctgctttggaaatctttttgtcattggcatgaga tctttcattaaagctgaaaatacaactcacgctatgtccatcaaaatcctttgttgtgct gattgcctgatgggtgtttacttgttctttgttggcattttcgatataaaataccgaggg cagtatcagaagtatgccttgctgtggatggagagcgtgcagtgccgcctcatggggttc ctggccatgctgtccaccgaagtctctgttctgctactgacctacttgactttggagaag ttcctggtcattgtcttccccttcagtaacattcgacctggaaaacggcagacctcagtc atcctcatttgcatctggatggcgggatttttaatagctgtaattccattttggaataag gattattttggaaacttttatgggaaaaatggagtatgtttcccactttattatgaccaa acagaagatattggaagcaaagggtattctcttggaattttcctaggtgtgaacttgctg gcttttctcatcattgtgttttcctatattactatgttctgttccattcaaaaaaccgcc ttgcagaccacagaagtaaggaattgttttggaagagaggtggctgttgcaaatcgtttc ttttttatagtgttctctgatgccatctgctggattcctgtatttgtagttaaaatcctt tccctcttccgggtggaaataccagacacaatgacttcctggatagtgatttttttcctt ccagttaacagtgctttgaatccaatcctctatactctcacaaccaacttttttaaggac aagttgaaacagctgctgcacaaacatcagaggaaatcaattttcaaaattaaaaaaaaa agtttatctacatccattgtgtggatagaggactcctcttccctgaaacttggggttttg aacaaaataacacttggagacagtataatgaaaccagtttcctag

Homo sapiens (human): 339403 Help Entry 339403            CDS       T01001                                  Symbol RXFP4, GPCR142, GPR100, RLN3R2, RXFPR4 Name (RefSeq) relaxin family peptide/INSL5 receptor 4   KO K08398   relaxin family peptide receptor 4 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04926   Relaxin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     339403 (RXFP4)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     339403 (RXFP4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     339403 (RXFP4) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Relaxin     339403 (RXFP4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 7TM_GPCR_Srsx Motif Other DBs NCBI-GeneID:  339403 NCBI-ProteinID:  NP_871001 OMIM:  609043 HGNC:  14666 Ensembl:  ENSG00000173080 UniProt:  Q8TDU9 Structure PDBPDBj LinkDB All DBs Position 1:155941638..155943087 Genome browser AA seq 374 aa AA seqDB search MPTLNTSASPPTFFWANASGGSVLSADDAPMPVKFLALRLMVALAYGLVGAIGLLGNLAV LWVLSNCARRAPGPPSDTFVFNLALADLGLALTLPFWAAESALDFHWPFGGALCKMVLTA TVLNVYASIFLITALSVARYWVVAMAAGPGTHLSLFWARIATLAVWAAAALVTVPTAVFG VEGEVCGVRLCLLRFPSRYWLGAYQLQRVVLAFMVPLGVITTSYLLLLAFLQRRQRRRQD SRVVARSVRILVASFFLCWFPNHVVTLWGVLVKFDLVPWNSTFYTIQTYVFPVTTCLAHS NSCLNPVLYCLLRREPRQALAGTFRDLRLRLWPQGGGWVQQVALKQVGRRWVASNPRESR PSTLLTNLDRGTPG NT seq 1125 nt NT seq  +upstreamnt  +downstreamnt atgcccacactcaatacttctgcctctccacccacattcttctgggccaatgcctccgga ggcagtgtgctgagtgctgatgatgctccgatgcctgtcaaattcctagccctgaggctc atggttgccctggcctatgggcttgtgggggccattggcttgctgggaaatttggcggtg ctgtgggtactgagtaactgtgcccggagagcccctggcccaccttcagacaccttcgtc ttcaacctggctctggcggacctgggactggcactcactctccccttttgggcagccgag tcggcactggactttcactggcccttcggaggtgccctctgcaagatggttctgacggcc actgtcctcaacgtctatgccagcatcttcctcatcacagcgctgagcgttgctcgctac tgggtggtggccatggctgcggggccaggcacccacctctcactcttctgggcccgaata gccaccctggcagtgtgggcggcggctgccctggtgacggtgcccacagctgtcttcggg gtggagggtgaggtgtgtggtgtgcgcctttgcctgctgcgtttccccagcaggtactgg ctgggggcctaccagctgcagagggtggtgctggctttcatggtgcccttgggcgtcatc accaccagctacctgctgctgctggccttcctgcagcggcggcaacggcggcggcaggac agcagggtcgtggcccgctctgtccgcatcctggtggcttccttcttcctctgctggttt cccaaccatgtggtcactctctggggtgtcctggtgaagtttgacctggtgccctggaac agtactttctatactatccagacgtatgtcttccctgtcactacttgcttggcacacagc aatagctgcctcaaccctgtgctgtactgtctcctgaggcgggagccccggcaggctctg gcaggcaccttcagggatctgcggttgaggctgtggccccagggcggaggctgggtgcaa caggtggccctaaagcaggtaggcaggcggtgggtcgcaagcaacccccgggagagccgc ccttctaccctgctcaccaacctggacagagggacacccgggtga

Homo sapiens (human): 51289 Help Entry 51289             CDS       T01001                                  Symbol RXFP3, GPCR135, RLN3R1, RXFPR3, SALPR Name (RefSeq) relaxin family peptide receptor 3   KO K08397   relaxin family peptide receptor 3 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04926   Relaxin signaling pathway Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     51289 (RXFP3)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     51289 (RXFP3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     51289 (RXFP3) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Relaxin     51289 (RXFP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  7tm_1 DUF8676 Motif Other DBs NCBI-GeneID:  51289 NCBI-ProteinID:  NP_057652 OMIM:  609445 HGNC:  24883 Ensembl:  ENSG00000182631 UniProt:  Q9NSD7 Structure PDBPDBj LinkDB All DBs Position 5:33936386..33938918 Genome browser AA seq 469 aa AA seqDB search MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGA PPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLF VTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTR YHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVK VMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAA GTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFS QEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTA TTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY NT seq 1410 nt NT seq  +upstreamnt  +downstreamnt atgcagatggccgatgcagccacgatagccaccatgaataaggcagcaggcggggacaag ctagcagaactcttcagtctggtcccggaccttctggaggcggccaacacgagtggtaac gcgtcgctgcagcttccggacttgtggtgggagctggggctggagttgccggacggcgcg ccgccaggacatcccccgggcagcggcggggcagagagcgcggacacagaggcccgggtg cggattctcatcagcgtggtgtactgggtggtgtgcgccctggggttggcgggcaacctg ctggttctctacctgatgaagagcatgcagggctggcgcaagtcctctatcaacctcttc gtcaccaacctggcgctgacggactttcagtttgtgctcaccctgcccttctgggcggtg gagaacgctcttgacttcaaatggcccttcggcaaggccatgtgtaagatcgtgtccatg gtgacgtccatgaacatgtacgccagcgtgttcttcctcactgccatgagtgtgacgcgc taccattcggtggcctcggctctgaagagccaccggacccgaggacacggccggggcgac tgctgcggccggagcctgggggacagctgctgcttctcggccaaggcgctgtgtgtgtgg atctgggctttggccgcgctggcctcgctgcccagtgccattttctccaccacggtcaag gtgatgggcgaggagctgtgcctggtgcgtttcccggacaagttgctgggccgcgacagg cagttctggctgggcctctaccactcgcagaaggtgctgctgggcttcgtgctgccgctg ggcatcattatcttgtgctacctgctgctggtgcgcttcatcgccgaccgccgcgcggcg gggaccaaaggaggggccgcggtagccggaggacgcccgaccggagccagcgcccggaga ctgtcgaaggtcaccaaatcagtgaccatcgttgtcctgtccttcttcctgtgttggctg cccaaccaggcgctcaccacctggagcatcctcatcaagttcaacgcggtgcccttcagc caggagtatttcctgtgccaggtatacgcgttccctgtgagcgtgtgcctagcgcactcc aacagctgcctcaaccccgtcctctactgcctcgtgcgccgcgagttccgcaaggcgctc aagagcctgctgtggcgcatcgcgtctccttcgatcaccagcatgcgccccttcaccgcc actaccaagccggagcacgaggatcaggggctgcaggccccggcgccgccccacgcggcc gcggagccggacctgctctactacccacctggcgtcgtggtctacagcggggggcgctac gacctgctgcccagcagctctgcctactga

Homo sapiens (human): 59350 Help Entry 59350             CDS       T01001                                  Symbol RXFP1, LGR7, RXFPR1 Name (RefSeq) relaxin family peptide receptor 1   KO K04306   relaxin family peptide receptor 1 Organism hsa  Homo sapiens (human) Pathway hsa04080   Neuroactive ligand-receptor interaction hsa04926   Relaxin signaling pathway Drug target Serelaxin:  D10488 Brite KEGG Orthology (KO) [BR:hsa00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04080 Neuroactive ligand-receptor interaction     59350 (RXFP1)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     59350 (RXFP1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04030 G protein-coupled receptors [BR:hsa04030]     59350 (RXFP1) G protein-coupled receptors [BR:hsa04030]  Rhodopsin family   Peptide    Relaxin     59350 (RXFP1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 7tm_1 LRR_4 LRR_5 LRR_1 LRR_9 Ldl_recept_a LRRNT LRR_EndoS LRR_LRWD1 LRR_Zer-1 Motif Other DBs NCBI-GeneID:  59350 NCBI-ProteinID:  NP_067647 OMIM:  606654 HGNC:  19718 Ensembl:  ENSG00000171509 UniProt:  Q9HBX9 Structure PDBPDBj LinkDB All DBs Position 4:158521714..158653372 Genome browser AA seq 757 aa AA seqDB search MTSGSVFFYILIFGKYFSHGGGQDVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED NCGDNNGWSLQFDKYFASYYKMTSQYPFEAETPECLVGSVPVQCLCQGLELDCDETNLRA VPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLY LSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDK PLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDEL DLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQ RMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTC FGNIFVICMRPYIRSENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWM ESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFRCVRPGKCRTITVLILIWITGF IVAFIPLSNKEFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYG SMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGT ITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKGQKTYAPSFIWV EMWPLQEMPPELMKPDLFTYPCEMSLISQSTRLNSYS NT seq 2274 nt NT seq  +upstreamnt  +downstreamnt atgacatctggttctgtcttcttctacatcttaatttttggaaaatatttttctcatggg ggtggacaggatgtcaagtgctcccttggctatttcccctgtgggaacatcacaaagtgc ttgcctcagctcctgcactgtaacggtgtggacgactgcgggaatcaggccgatgaggac aactgtggagacaacaatggatggtctctgcaatttgacaaatattttgccagttactac aaaatgacttcccaatatccttttgaggcagaaacacctgaatgtttggtcggttctgtg ccagtgcaatgtctttgccaaggtctggagcttgactgtgatgaaaccaatttacgagct gttccatcggtttcttcaaatgtgactgcaatgtcacttcagtggaacttaataagaaag cttcctcctgattgcttcaagaattatcatgatcttcagaagctgtacctgcaaaacaat aagattacatccatctccatctatgctttcagaggactgaatagccttactaaactgtat ctcagtcataacagaataaccttcctgaagccgggtgtttttgaagatcttcacagacta gaatggctgataattgaagataatcacctcagtcgaatttccccaccaacattttatgga ctaaattctcttattctcttagtcctgatgaataacgtcctcacccgtttacctgataaa cctctctgtcaacacatgccaagactacattggctggaccttgaaggcaaccatatccat aatttaagaaatttgacttttatttcctgcagtaatttaactgttttagtgatgaggaaa aacaaaattaatcacttaaatgaaaatacttttgcacctctccagaaactggatgaattg gatttaggaagtaataagattgaaaatcttccaccgcttatattcaaggacctgaaggag ctgtcacaattgaatctttcctataatccaatccagaaaattcaagcaaaccaatttgat tatcttgtcaaactcaagtctctcagcctagaagggattgaaatttcaaatatccaacaa aggatgtttagacctcttatgaatctctctcacatatattttaagaaattccagtactgt gggtatgcaccacatgttcgcagctgtaaaccaaacactgatggaatttcatctctagag aatctcttggcaagcattattcagagagtatttgtctgggttgtatctgcagttacctgc tttggaaacatttttgtcatttgcatgcgaccttatatcaggtctgagaacaagctgtat gccatgtcaatcatttctctctgctgtgccgactgcttaatgggaatatatttattcgtg atcggaggctttgacctaaagtttcgtggagaatacaataagcatgcgcagctgtggatg gagagtactcattgtcagcttgtaggatctttggccattctgtccacagaagtatcagtt ttactgttaacatttctgacattggaaaaatacatctgcattgtctatccttttagatgt gtgagacctggaaaatgcagaacaattacagttctgattctcatttggattactggtttt atagtggctttcattccattgagcaataaggaatttttcaaaaactactatggcaccaat ggagtatgcttccctcttcattcagaagatacagaaagtattggagcccagatttattca gtggcaatttttcttggtattaatttggccgcatttatcatcatagttttttcctatgga agcatgttttatagtgttcatcaaagtgccataacagcaactgaaatacggaatcaagtt aaaaaagagatgatccttgccaaacgttttttctttatagtatttactgatgcattatgc tggatacccatttttgtagtgaaatttctttcactgcttcaggtagaaataccaggtacc ataacctcttgggtagtgatttttattctgcccattaacagtgctttgaacccaattctc tatactctgaccacaagaccatttaaagaaatgattcatcggttttggtataactacaga caaagaaaatctatggacagcaaaggtcagaaaacatatgctccatcattcatctgggtg gaaatgtggccactgcaggagatgccacctgagttaatgaagccggaccttttcacatac ccctgtgaaatgtcactgatttctcaatcaacgagactcaattcctattcatga

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